Search for the Standard Model Higgs boson production in association with top quarks in pp collisions at 8 TeV with the ATLAS detector

The search for the production of the Higgs boson associated with a pair of top quarks in the ATLAS experiment is presented. It focuses on Higgs bosons decaying to $b\bar{b}$ and events containing two leptons (electrons and/or muons). It uses 20.3 fb$^{-1}$ of $pp$ collision data at $\sqrt{s}$ = 8 TeV collected with the ATLAS detector at the LHC in 2012. No significant excess of events is found and the 95% CL observed (expected) limit is 7.0xSM (4.3xSM). After combining with the single lepton final state an observed (expected) limit of 4.1xSM (2.6xSM) with a best fit of $\mu=1.7\pm1.4$ is obtained.Comment: TOP 2014 workshop, ATL-PHYS-PROC-2014-26

Commissioning of the ATLAS reconstruction software with first data

Looking towards first LHC collisions, the ATLAS detector is being commissioned using the physics data available: cosmic rays and data taken during the LHC single beam operations at 450 GeV. During the installation of the ATLAS detector in the cavern, cosmic rays were collected with the different parts of the detector that were available. Combined cosmic runs taken with the full installed detector with and without magnetic field as well as a few single beam events recently recorded are being used to commission the full system prior to the first proton collisions.Comment: ICHEP08, 5 pages, 11 figure

RADIOGIS software that can be incorporated to ArcView 9 as a new toolbar for the calculation of radioelectric coverage of radiocommunication systems.

[ESP]1. Cálculos: • Coberturas de potencia, de campo eléctrico o de densidad de potencia. Modelos de propagación: Entorno rural: Meeks y UITR-526- Entorno urbano: Hata, COST231 y Xia-Bertoni.- Indoor: Trazado de rayos y UTD.• Porcentaje sobre umbral: utilizando una capa vectorial que contenga términos municipales, términos provinciales, carreteras, comarcas, distritos municipales, etc.; o bien sobre un polígono, línea o rectángulo.2. Gestión de Bases de Datos. • De emplazamientos.• De coberturas radioeléctricas de potencia.• De mapas de densidad de potencia o de campo eléctrico.• De sistemas de potencia. • De mapas múltiples de potencia o de campo eléctrico.• Campañas de medidas.• Operaciones de gran utilidad con información raster.[ENG] 1. Calculations • Power, electric field or power density coverage • Propagation models: - Rural environment: Meeks and UITR-526 - Urban environment: Hata, COST231 and Xia-Bertoni - Indoor: Ray tracing and UTD • Percentage over threshold using a vectorial layer which includes municipal areas, provincial areas, roads, districts, etc. or with reference to a polygon, a line or a rectangleB. Management of Databases• Location databases • Power radioelectric coverage databases • Power density or electric field maps databases• Power systems databases • Multiple power or electric field maps databases • Measurement campaigns • Highly useful operations with raster information databases[ESP]RADIOGIS es una herramienta basada en el Sistema de Información Geográfica (SIG) ARCVIEW 9 y desarrollada por el Grupo (SiCoMo) de la Universidad Politécnica de Cartagena, España. RADIOGIS aprovecha todas las facilidades de tratamiento de la información de los SIG, y es tanto un software de gestión de bases de datos de sistemas de radiocomunicaciones como una potente herramienta para el cálculo radioeléctrico. Nuestro objetivo es alcanzar acuerdos de cooperación tecnológica para ofrecer la tecnología al mercado. Los potenciales clientes son pequeñas empresas que deseen planificar sistemas de radiocomunicaciones como GSM, UMTS, TETRA, LMDS, MMDS, WiFi o TDT.[ENG]RADIOGIS is a radio planning tool based on the Geographic Information System (GIS) ARCVIEW 8.2 and developed by the SiCoMo Group at the Technical University of Cartagena, Spain. RADIOGIS takes advantage of all of the SIG facilities for treatment of information and therefore, is both a software for the management of radiocommunication systems databases and a powerful tool for radioelectric calculation. Our aim is to achieve tecnological agreement to offer this technology to the market. The potential clients are telecommunication enterprises, which need application for planning radio communication systems GSM, UMTS, TETRA, LMDS, MMDS, WiFi o TDT.[ESP]- Reducción de costes - Versatilidad [ENG] - Reduction in costs - Versatility[ESP]“Desarrollo e implementación de modelos de propagación electromagnéticos para la predicción de parámetros del canal de radiocomunicaciones.”Las medidas que se realizan están encaminadas a validar y ajustar los modelos de propagación desarrollados y a conocer las particularidades del canal de radiocomunicaciones en cada tipo de entorno (rural, urbano, interiores, etc.). Además de medidas en banda estrecha para estimar las pérdidas por propagación y que encuentran aplicación en la planificación de sistemas de comunicaciones móviles de primera y segunda generación (como el GSM), en estos momentos, se están llevando a cabo medidas de banda ancha que evalúan no sólo las pérdidas sino también la dispersión del canal en el tiempo y en el espacio y que encuentran aplicación en sistemas de tercera generación como el UMTS. Las medidas se centran en entornos microcelulares y entornos especiales como túneles.“Desarrollo de aplicaciones informáticas basadas en sistemas de información geográfica (SIG) para la planificación de sistemas de comunicaciones móviles.” Las herramientas informáticas son cada vez más necesarias para la planificación óptima y eficiente de los sistemas de comunicaciones móviles. Estas herramientas tienen que ser capaces de manejar gran volumen de información espacial (modelo digital del terreno, mapas de tráfico, mapas de cobertura radioeléctrica, etc.). Por ello, en el grupo se desarrollan aplicaciones que basadas en sistemas de información geográfica, encuentran aplicación en la planificación de sistemas de radiocomunicaciones digitales.[ENG] “Development and implementation of electromagnetic propagation models for the prediction of radio channel parameters.”This line of research concerns propagation models which forecast the propagation losses as well as the dispersion in time and space introduced by the radio channel. These models are developed from electromagnetic theories based on Physical Optics and Geometrical Optics in addition to ray tracing techniques, and are implemented in a high-level programming language such as C++. Currently, microcellular urban environments as well as special ones such as tunnels are under study, achieving MIMO-channel models (Multiple Inputs Multiple Outputs) which yield a higher speed data transmission in the radio interface without needing greater bandwidth. “Experimental radio channel measurements.” The undertaken measurements are aimed at validating and refining the developed propagation models and at studying the particularities of the radio channel in every kind of environment (rural, urban, indoor, etc.). Apart from narrow-bandwidth measurements to estimate the propagation losses, which can find application in the planning of first and second generation mobile communications systems (as GSM), at the present time, wide-bandwidth measurements as well as MIMO channel measurements are also being carried out. The wide-bandwidth measurements are undertaken in order to evaluate, not only the mentioned propagation losses, but the channel dispersion in time and space, and could be applied in third generation systems such as UMTS. The MIMO channel measurements use multiple antennas in both the transmission and reception and significantly succeed in improving the channel capacity. Both kind of measurements are focused on microcellular environments and special ones such as tunnels. “Software development based on Geographic Information Systems (GIS) for the planning of mobile communication systems.” Computing tools are turning out to be an essential step for an optimal and efficient planning of mobile communication systems. These tools must be able to handle a big amount of spatial information (digital terrain model, traffic maps, radioelectric coverage, etc.). Therefore, the research group is developing applications which, based on Geographic Information Systems, can be applied in the planning of digital radiocommunication systems

El primado del romano Pontífice en Juan de Torquemada

Como es sabido, la Summa de Ecclesia constituye la obra cumbre de la producción teológica de Juan de Torquemada, y ha ejercido notable influencia en los teólogos posteriores. Y, dentro de ella, el libro II, objeto de nuestro estudio, trata del Primado del Romano Pontífice

Nanocellulose Oxidation - Fundamentals and Application in Hydrogels

The adaptable surface chemistry of cellulose nanocrystals (CNCs) makes them outstanding; it provides colloidal stability, which is essential for engineering use, to commercially-available CNCs. Colloidal stability is achieved by the bulky negatively-charged sulfate half-ester groups on the surface that it manufactures itself via the use of sulfuric acid. The surface chemistry of CNCs can also be adapted into dialdehyde cellulose nanocrystals (DAC) by periodate oxidation in the presence of the sulfate half-ester groups. The oxidation extends the range of applications of CNCs. The objective of this thesis is to elucidate the role played by the sulfate half-ester groups on the oxidation reaction, both in the kinetics and its products. The results demonstrate that the oxidation reaction reduces the number of sulfate half-ester groups, which impacts on the colloidal stability, the size of the resulting product properties and, consequently, the DAC applications. A rheology study and a proof-of-concept demonstration are also performed to verify whether CNC derivatives could reinforce emulsions solidified by gelatin, as this could extend the range of CNCs in the field of microwave technology to be used as a fat phantom. The gelatin emulsions reinforced by CNC derivatives maintain the storage modulus above the loss modulus at temperatures above 40 \ubaC. The thermal stability of the reinforced emulsions could permit the successful implementation of these gels in the field of microwave technology. CNCs are possibly the better candidate than DAC for the reinforcement due to a combination of the ease of the phantom production and performance

TMCO1 mediates cancer cell migration through regulating microtubule assembling

Transmembrane and coiled-coil domains 1 (TMCO1) is highly conserved in amino acid sequence among species and ubiquitously expressed in all human tissues. Homozygous frameshift mutation in TMCO1 causes distinctive craniofacial dysmorphism, skeletal anomalies, and mental retardation. However, its physiological functions, particularly in cancer biology, are largely unknown. In this study, we have found that knock down of TMCO1 in HeLa cells, a human cervical cancer cell line, and U2OS cells, an osteosarcoma cell line, remarkably inhibited their migratory capability; TMCO1 was highly expressed in the cells of the invasive front of high grade lung cancer and metastatic cancer cells in the clinical specimens, and lung cancer cells at the metastatic bone site in our animal model; Immunohistostaining revealed that TMCO1 was co-localized with microtubules and was able to be co-sedimentated with microtubules in the presence of paclitaxel and GTP; and deficiency of TMCO1 in cells dramatically increased acetylation of tubulin. Further investigation demonstrated that TMCO1 impacted microtubule dynamics, which is closely correlated with cancer metastasis, TBA drug response and therapeutic prognosis. Our findings provide not only new mechanistic insights into cancer metastasis, but also critically evaluate the significance of TMCO1 as a novel target for therapeutic treatment of the disease.https://engagedscholarship.csuohio.edu/u_poster_2015/1016/thumbnail.jp

Spatial evaluation between air pollution and health in areas with limitation of data

A poluição do ar é um grave problema de saúde pública a nível mundial. Os estudos que investigam a relação entre poluição atmosférica e saúde humana são a base para a gestão que visa promover o desenvolvimento urbano e qualidade de vida. Nesse sentido, a disponibilidade de dados é uma premissa inicial para esses estudos, sobretudo, para os que têm o enfoque na avaliação espacial. O problema é que muitos centros urbanos ainda carecem de um sistema de armazenamento, consolidação e disponibilização dos dados. Diante desse cenário, este artigo teve como objetivo propor um método para avaliação espacial entre poluição do ar e saúde em áreas urbanas que têm limitações na disponibilidade de dados. O método proposto foi baseado em procedimentos de orientação a objetos para integração de um banco de dados geográficos, considerando dados de internações e inventário de poluição do ar. Posteriormente, foi realizada uma análise de correlação e regressão espacial - Ordinary Least Square (OLS). Os resultados mostraram que o método proposto é uma alternativa viável para as áreas com limitações de dados. As análises de correlação e regressão apresentaram uma relação significante (p < 0,05) entre poluição e saúde.Air pollution is a serious public health problem worldwide. Studies that investigate the relationship between air pollution and human health are fundamental for management that aims to promote the urban development and life quality. Data availability is an initial premise for these studies, especially, for it that have focus in the spatial evaluation. The problem is that many urban centers do not have a system to consolidate and storage data. Thus, this paper aimed to propose a method for spatial evaluation between air pollution and health in urban areas that have limitation in data availability. The method proposed was based on object orientation for geographic information system, considering hospital admissions data and air pollution inventories. Also, was applied a correlation analysis and a spatial regression - Ordinary Least Square (OLS). Results showed that the method proposed is an alternative for area with data availability. Correlations analysis and regression showed a significant relationship (p< 0.05) between air pollution and health

Utility of the SENIORS elderly heart failure risk model applied to the RICA registry of acute heart failure

Background: Heart failure (HF) is predominantly a disease of the elderly. Reliable risk stratification would help in the management of this population, but no model has been well evaluated in elderly HF patients in both acute and chronic settings and not being restricted by ejection fraction. To evaluate the utility of the SENIORS risk model, developed from a clinical trial of elderly patients with chronic HF, in an independent cohort (National Spanish Registry: RICA) of elderly acute HF patients. Methods: We applied the SENIORS risk model to 926 patients in RICA to estimate risk at one year of a) composite outcome of all-cause mortality or cardiovascular hospital admission and b) all-cause mortality. Results: In the RICA registry mean age was 78 years, mean ejection fraction 51% and 87% were in NYHA II and III. At one year death/CV hospitalization occurred in 31.9% and all-cause mortality in 19.5%. The risk model provided good separation of Kaplan Meier curves stratified by tertile for death/CV hospitalization and all-cause mortality. The observed versus expected rates of death/CV hospitalization in the lowest, middle and highest risk tertiles were (%) 34/24, 45/41 and 57/67, and for death 13/16, 32/38 and 44/70 respectively. C-statistic for all-cause mortality or CV hospitalization was 0.60 and for all-cause mortality 0.66. Conclusion: The SENIORS risk model was a reliable tool for relative risk stratification among acute heart failure patients in a “real world” registry, but predicted versus observed risk showed some variability. The model provides a useful basis for clinical risk prediction

Simulation des transferts de chaleur à l'impact de jets supersoniques chauds sous-détendus

Cette étude a pour but de simuler les échanges thermiques sur une paroi plane impactée par un jet supersonique chaud sous-détendu. Divers modèles de turbulence et schémas numériques sont testés sur des configurations de jet libre et impactant afin de surmonter la combinaison de difficultés liées à ce type de simulation. Les résultats sont confrontés aux relations empiriques établies dans la littérature. Le profil de Nusselt sur la paroi, obtenu expérimentalment par le biais de la “méthode inverse”, permettra de valider finement les simulations lors de la phase finale de cette étude

Salt glands in Maledictosuchus riclaensis (Metriorhynchidae, Thalattosuchia) from the Callovian of the Iberian Peninsula

Maledictosuchus riclaensis is a Callovian metriorhynchid from the Iberian Peninsula. Metriorhynchids are marine crocodylomorphs that evolved numerous adaptations to a pelagic life-style. As well as morphological adaptations, they evolved hypertrophied salt glands, which imply a high degree of specialization. These glands were described in two metriorhynchid species. The salt glands control the ionic concentration balance in the organism. As they are soft tissue, they hardly fossilize. In the last years, computerized tomography has achieved great importance in palaeontological research, since it allows the visualization and study of the internal bone structures and the 3D digitalization in a non-invasive way and without putting the specimen at risk. The holotype of Maledictosuchus riclaensis consists on a very well preserved skull and three vertebrae. A computerized tomography of the skull shows the presence of hypertrophied salt glands in this taxonMaledictosuchus riclaensis es un metriorrínquido del Calloviense de la Península Ibérica. Los metriorrinquidos son un grupo de crocodilomorfos marinos que desarrollaron numerosas adaptaciones al medio marino pelágico. Además de adaptaciones morfológicas, desarrollaron glándulas de la sal hipertrofiadas, lo cual implica un alto grado de especialización. Estas glándulas se han descrito en dos especies de metriorrínquidos. Las glándulas de la sal se encargan de controlar el balance de la concentración de sales en el organismo. Al tratarse de tejidos blandos su preservación es muy poco frecuente. La tomografía computarizada ha alcanzado en los últimos años gran importancia en la investigación paleontológica, ya que permite la visualización y estudio de las estructuras internas de los huesos y su digitalización en 3D, de una forma no invasiva y sin poner en riesgo al ejemplar. El holotipo de Maledictosuchus riclaensis consiste en un cráneo muy bien preservado y tres vértebras. Una tomografía computarizada del cráneo reveló la presencia de glándulas de la sal hipertrofiadas en este taxó