411 research outputs found
Numerical simulation and experimental validation of the hydrodynamics in a 350 kW bubbling fluidized bed combustor
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 29/01/2016
- Field of study
This paper presents experimentally validated three-dimensional numerical simulation of a 350 kW pilotscale bubbling fluidized bed combustor, which has been developed by using commercial CFD software package, Fluent 14.5. The solid particle distribution has been simulated by using the multiphase Euler–Euler Approach. The gas–solid momentum exchange coefficients were calculated by using Syamlal and O’Brien drag functions. The CFD model is created as the realistic representation of the actual pilot-scale bubbling fluidized bed. All simulations are performed in transient mode for an operation time of about 350 s. The experimental study is performed with silica sand particles with mean particle size of 0.6 mm and density of 1639 kg/m3. The bed was filled with particles up to a height of 0.30 m. The same conditions are used for the simulations. The present work combines both experimental and computational studies, where the CFD-Simulation results are compared to those obtained by experiments. The predicted simulation results of minimum fluidization velocity and pressure drop values of the pilot-scale bubbling fluidized bed combustor have good agreement with the experimental measurements
Intercostal nerve mononeuropathy: study of 14 cases
- Author
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- Field of study
Nucleolin Inhibits G4 Oligonucleotide Unwinding by Werner Helicase
- Author
- A De
- A Pollice
- A Scherl
- AA Cohen
- AK Leung
- Brosh RM Jr
- C von Kobbe
- C von Kobbe
- C Yang
- C Yang
- CE Ogburn
- CE Yu
- CF Semenkovich
- Chakravarty Devulapalli
- D Hernandez-Verdun
- D Sen
- F Rossi
- FE Indig
- France Carrier
- Fred E. Indig
- H Ginisty
- H Sun
- Haiqing Fu
- Ivana Rybanska
- J Shen
- JA Harrigan
- JC Shen
- JJ Partridge
- JP Laine
- JS Andersen
- K Kim
- Kerstin Borgmann
- L Bjergbaek
- LA Dempsey
- LA Hanakahi
- M Fromont-Racine
- M Fry
- M Otterlei
- M Poot
- M Poot
- M Shiratori
- MD Gray
- MD Gray
- MD Huber
- MD Huber
- MK Danks
- N Nalabothula
- N Suzuki
- N Suzuki
- P Karmakar
- P Pichierri
- P Pourquier
- Parimal Karmakar
- PL Opresko
- PL Opresko
- R Ochs
- R Vaitiekunaite
- RA Borer
- RA Marciniak
- RJ Schulte
- S Huang
- S Sakamoto
- S Zhang
- SA Gerbi
- SP Linke
- T Pederson
- T Suzuki
- V Gonzalez
- Vilhelm A. Bohr
- Y Daniely
- Y Daniely
- Y Pommier
- Y Wang
- YW Lam
- Z Mi
- Publication venue
- Public Library of Science
- Publication date
- 04/06/2012
- Field of study
The Werner protein (WRNp), a member of the RecQ helicase family, is strongly associated with the nucleolus, as is nucleolin (NCL), an important nucleolar constituent protein. Both WRNp and NCL respond to the effects of DNA damaging agents. Therefore, we have investigated if these nuclear proteins interact and if this interaction has a possible functional significance in DNA damage repair.Here we report that WRNp interacts with the RNA-binding protein, NCL, based on immunoprecipitation, immunofluorescent co-localization in live and fixed cells, and direct binding of purified WRNp to nucleolin. We also map the binding region to the C-terminal domains of both proteins. Furthermore, treatment of U2OS cells with 15 µM of the Topoisomerase I inhibitor, camptothecin, causes the dissociation of the nucleolin-Werner complex in the nucleolus, followed by partial re-association in the nucleoplasm. Other DNA damaging agents, such as hydroxyurea, Mitomycin C, and aphidicolin do not have these effects. Nucleolin or its C-terminal fragment affected the helicase, but not the exonuclease activity of WRNp, by inhibiting WRN unwinding of G4 tetraplex DNA structures, as seen in activity assays and electrophoretic mobility shift assays (EMSA).These data suggest that nucleolin may regulate G4 DNA unwinding by WRNp, possibly in response to certain DNA damaging agents. We postulate that the NCL-WRNp complex may contain an inactive form of WRNp, which is released from the nucleolus upon DNA damage. Then, when required, WRNp is released from inhibition and can participate in the DNA repair processes
A comparative study on gaseous fuel generation capability of biomass materials by thermo-chemical gasification using stoichiometric quasi-steady-state model
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Gene switching rate determines response to extrinsic perturbations in the self-activation transcriptional network motif
- Author
- A Becskei
- A Becskei
- A d’Onofrio
- A Eldar
- A Graudenzi
- A Raj
- B Verd
- BE Stranger
- C Van den Broeck
- CV Rao
- CV Rao
- D Frigola
- DF Chu
- DM Suter
- DT Gillespie
- DT Gillespie
- F Bertaux
- F Cappuzzo
- F Schoegl
- G Cai
- G Caravagna
- G Caravagna
- G Nicolis
- H Ge
- HH Chang
- HS Wio
- I Prigogine
- J Garcia-Ojalvo
- J Hasty
- J Jaruszewicz
- J Simicevic
- JS Griffith
- K Puszynski
- K Puszynski
- L Cai
- L Wang
- LS Tsimring
- M Acar
- M Assaf
- M Ko
- M Shiino
- M Thattai
- M Thattai
- M Weber
- MB Elowitz
- MK M
- NI Markevich
- NR Zabet
- NR Zabet
- NV Mantzaris
- O Cinquin
- P Paszek
- P Smolen
- P Smolen
- P Smolen
- PB Detwiler
- PS Gutierrez
- Q Liu
- R Barbuti
- R Karmakar
- R Karmakar
- R Losick
- RV Bobryk
- S de Franciscis
- T Lipniacki
- TB Kepler
- TS Gardner
- V Shahrezaei
- VP Zhdanov
- W Xiong
- WJ Blake
- WJ Blake
- X-M Liu
- Y Li
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2016
- Field of study
International audienc
Large expert-curated database for benchmarking document similarity detection in biomedical literature search
- Author
- Aanei CM
- Abid MB
- Abramowitz MK
- Abu-Zaid A
- Afnan M
- Agarabi C
- Ahmad R
- Aizat WM
- Al-Farha AA
- Al-Lawama M
- Alanio A
- Alaux C
- Albiol J
- Albrecht DR
- Albuquerque LG
- Alimba CG
- Allardyce J
- Almeida GMF
- Alonso-Caneiro D
- Alper OM
- Amer SEDR
- Amiya E
- Ammerman BA
- Amorim RM
- An Q
- Andersen SU
- Aplin JD
- Argyropoulos C
- Armitage C
- Ascher DB
- Ashry M
- Asmann YW
- Assaeed AM
- Atack JM
- Atanasov AG
- Atchison DA
- Atkins GJ
- Atlas L
- Avery SV
- Avillach P
- Baade PD
- Backman L
- Badie C
- Bae T
- Baier D
- Baker CI
- Bakkach J
- Baldi A
- Ball E
- Bannon R
- Bansal A
- Bardot O
- Barnett AG
- Barraud P
- Basharat Z
- Basner M
- Batra J
- Baumert P
- Bazanova OM
- Beale A
- Beck CR
- Becker D
- Beddoe T
- Bell ML
- Benezeth Y
- Bengtsson-Palme J
- Berbesque C
- Berezikov E
- Bergsland N
- Berners-Price S
- Bernhardt P
- Berrevoet F
- Berry E
- Berthold M
- Bessa TB
- Beyene TJ
- Biedermann PHW
- Bijleveld E
- Billington C
- Birch J
- Bittner F
- Bitzer M
- Blakely RD
- Blanck O
- Blaskovich MAT
- Bleackley M
- Blombach F
- Blum R
- Boehme KA
- Boelaert M
- Bogdanos D
- Bonvin AMJJ
- Bosch C
- Bosch O
- Boudreau SA
- Bourgoin T
- Bourke E
- Bouvard D
- Boykin LM
- Bradley G
- Bradshaw W
- Bramoweth AD
- Brand T
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- Braun RJ
- Brenneisen P
- Bridges KM
- Brown JAL
- Brown P
- Browngardt C
- Brownlie J
- Bruhl A
- Bukowy-Bieryllo Z
- Bull JA
- Burt A
- Bush SJ
- Butler LM
- Byrareddy SN
- Byrne HJ
- Cabantous S
- Cai Y
- Calatayud S
- Campana LG
- Campbell M
- Candal E
- Cao Z
- Cao Z
- Cardoso P
- Carlson K
- Carter D
- Cascella M
- Casillas S
- Castelvetro V
- Caswell PT
- Catry T
- Cavalli G
- Cernava T
- Cerovsky V
- Chacko G
- Chagoyen M
- Chakraborty S
- Chan SS
- Chandrasekaran AR
- Chatzitheochari S
- Chavez-Fumagalli MA
- Chen B
- Chen C-E
- Chen C-S
- Chen DF
- Chen H
- Chen H
- Chen J-T
- Chen X
- Chen Y
- Cheng C
- Cheng J
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- Cheung JTK
- Chinapaw M
- Chinopoulos C
- Cho WCS
- Chong L
- Chowdhury D
- Chung H-J
- Chwalibog A
- Ciresi A
- Cobine PA
- Cockcroft S
- Coelho LP
- Colella V
- Conesa A
- Conway A
- Cook PA
- Cooper DN
- Cooper J
- Coqueret O
- Corea EM
- Cosacak MI
- Costa BM
- Costa E
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- Coupland C
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- Cruz AD
- Cui H
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- Cuiv PO
- Culver DC
- Cuypers M
- Cyr N
- D'Angiulli A
- Dahms TES
- Dai Z
- Daigle F
- Dalgleish R
- Dalrymple BP
- Danchin A
- Danielsen HE
- Darras S
- Daulatabad SV
- Davidson SM
- Day DA
- de Keersmaecker K
- de Leeuw F-E
- Dean LT
- Debrabant B
- Degirmenci V
- del Tredici AL
- Delahay RM
- Demaison L
- Denzel MS
- Deschodt M
- Devkota HP
- Devriendt K
- Dhariwal R
- Diao J
- Ding J
- Dings RPM
- Diouf B
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- Dlamini SV
- Dogan Y
- Domingues HS
- Dong XC
- Donner CF
- Dono M
- Doxey AC
- Dressick W
- Drevon CA
- Duan H
- Ducho C
- Ducommun B
- Dudley KJ
- Dufies M
- Duijf PHG
- Dumaz N
- Dwarakanath BS
- Ebell MH
- Echeverria N
- Ecke T
- Eckweiler D
- Eerola T
- Effiong A
- Ehret F
- Eisenhardt S
- Eixarch E
- El-Adawy H
- El-Esawi MA
- Elkum N
- Emmrich JV
- Engel MS
- Engel N
- Epp T
- Erickson TB
- Esfahlani SS
- Eskelinen E-L
- Eskew EA
- Esnakul AK
- Eustace AJ
- Evangelou E
- Fairhead M
- Falk S
- Fallah M
- Falter-Wagner CM
- Fan X
- Farber DB
- Faville MJ
- Feghali KA
- Fejzo MS
- Fernandez-Triana J
- Festa F
- Feteira A
- Feyerabend F
- Fierz W
- Filipp FV
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- Flegel WA
- Flood-Page P
- Florio T
- Forano E
- Forsayeth J
- Fox SA
- Franks SJ
- Frentiu FD
- Friebe M
- Frilander MJ
- Fu X
- Fujita S
- Furuta S
- Fuss J
- Gabrielsen M
- Gajda M
- Galea I
- Galluzzi L
- Gani F
- Ganpule AP
- Gao J
- Garcia-Alix A
- Gatchell M
- Gaullier G
- Gedye K
- Gelfer Y
- Ghelardi E
- Gill MR
- Gilliham M
- Giordano M
- Giunta C
- Gladue DP
- Gleeson PA
- Gloyn L
- Gnasso A
- Goarant C
- Gobet A
- Goggs R
- Gong H
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- Goodin A
- Goodyear CS
- Gora D
- Gough MJ
- Govender P
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- Goyal R
- Graham EB
- Graham KE
- Grande-Perez A
- Graves PM
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- Greidanus H
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- Grice D
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- Groen EJN
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- Grunau C
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- Gruneberg P
- Grybos M
- Guisado JL
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- Gumulya Y
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- Gurevich VV
- Gurney-Champion OJ
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- Gutierrez-Sacristan A
- Habes M
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- Hage SR
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- Haller DM
- Hammerschmidt S
- Han H
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- Handfield M
- Hanson J
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- Hapuarachchi HC
- Harder T
- Hardingham JE
- Harrison P
- Hartmann MD
- Harvey DJ
- Haston S
- Heck M
- Heers M
- Heffler E
- Heinrich M
- Helantera H
- Herbelet S
- Hew KF
- Higginbottom DB
- Higuchi Y
- Hilton R
- Hiroi N
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- Hodzic E
- Hoenner X
- Hojsgaard D
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- Ikonomopoulou MP
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- Jibb LA
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- Jonscher KR
- Jorens PG
- Jorgensen JOL
- Josse C
- Joubert JW
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- Junior AM
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- Kamagata K
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- Kasian O
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- Khalid JM
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- Kijanka GS
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- Klempnauer K-H
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- Klump H
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- Korpela KM
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- Krebsbach PH
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- Kueberuwa G
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- Kurdak H
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- Kurniawan NA
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- Lachat C
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- Lagisz M
- Lai HM
- Laky B
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- Lloyd VK
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- Locci E
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- Lopez-Ruiz FJ
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- Luengo GS
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- Lundh L-G
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- Yeung AWK
- Yin C-C
- Yli-Kauhaluoma J
- Yoneyama H
- Yu Y
- Yuan G-C
- Yuh C-H
- Zabetakis I
- Zaccolo M
- Zaucha J
- Zeng C
- Zeng E
- Zevnik B
- Zhang C
- Zhang C
- Zhang J
- Zhang L
- Zhang L
- Zhang X
- Zhang Y
- Zhang Y
- Zhang Z
- Zhang Z
- Zhang Z-Y
- Zhao X
- Zhao Y
- Zhou K
- Zhou M
- Zhu S
- Ziegler A
- Zinke K
- Zuberbier T
- Publication venue
- OXFORD UNIV PRESS
- Publication date
- 29/10/2019
- Field of study
Document recommendation systems for locating relevant literature have mostly relied on methods developed a decade ago. This is largely due to the lack of a large offline gold-standard benchmark of relevant documents that cover a variety of research fields such that newly developed literature search techniques can be compared, improved and translated into practice. To overcome this bottleneck, we have established the RElevant LIterature SearcH consortium consisting of more than 1500 scientists from 84 countries, who have collectively annotated the relevance of over 180 000 PubMed-listed articles with regard to their respective seed (input) article/s. The majority of annotations were contributed by highly experienced, original authors of the seed articles. The collected data cover 76% of all unique PubMed Medical Subject Headings descriptors. No systematic biases were observed across different experience levels, research fields or time spent on annotations. More importantly, annotations of the same document pairs contributed by different scientists were highly concordant. We further show that the three representative baseline methods used to generate recommended articles for evaluation (Okapi Best Matching 25, Term Frequency–Inverse Document Frequency and PubMed Related Articles) had similar overall performances. Additionally, we found that these methods each tend to produce distinct collections of recommended articles, suggesting that a hybrid method may be required to completely capture all relevant articles. The established database server located at https://relishdb.ict.griffith.edu.au is freely available for the downloading of annotation data and the blind testing of new methods. We expect that this benchmark will be useful for stimulating the development of new powerful techniques for title and title/abstract-based search engines for relevant articles in biomedical research
Search for dark matter produced in association with a single top quark or a top quark pair in proton-proton collisions at s=13 TeV
- Author
- Aarrestad TK
- Abbaneo D
- Abbiendi G
- Abbrescia M
- Abdullah WAT Wan
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- Alvarez JD Ruiz
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- Neutelings I
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- Papavergou I
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- Postiau N
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- Poyraz D
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- Preiato F
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- Prokofyev O
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- Volkov A
- Volobouev I
- Vormwald B
- Vorobiev I
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- Yu I
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- Zahid S
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- Zorbilmez C
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- Zumerle G
- Zuo X
- Zuolo D
- Publication venue
- Publication date
- 01/01/2019
- Field of study
A search has been performed for heavy resonances decaying to ZZ or ZW in 2l2q final states, with two charged leptons (l = e, mu) produced by the decay of a Z boson, and two quarks produced by the decay of a W or Z boson. The analysis is sensitive to resonances with masses in the range from 400 to 4500 GeV. Two categories are defined based on the merged or resolved reconstruction of the hadronically decaying vector boson, optimized for high- and low-mass resonances, respectively. The search is based on data collected during 2016 by the CMS experiment at the LHC in proton-proton collisions with a center-of-mass energy of root s = 13 TeV, corresponding to an integrated luminosity of 35.9 fb(-1). No excess is observed in the data above the standard model background expectation. Upper limits on the production cross section of heavy, narrow spin-1 and spin-2 resonances are derived as a function of the resonance mass, and exclusion limits on the production of W' bosons and bulk graviton particles are calculated in the framework of the heavy vector triplet model and warped extra dimensions, respectively.A search has been performed for heavy resonances decaying to ZZ or ZW in 2l2q final states, with two charged leptons (l = e, mu) produced by the decay of a Z boson, and two quarks produced by the decay of a W or Z boson. The analysis is sensitive to resonances with masses in the range from 400 to 4500 GeV. Two categories are defined based on the merged or resolved reconstruction of the hadronically decaying vector boson, optimized for high- and low-mass resonances, respectively. The search is based on data collected during 2016 by the CMS experiment at the LHC in proton-proton collisions with a center-of-mass energy of root s = 13 TeV, corresponding to an integrated luminosity of 35.9 fb(-1). No excess is observed in the data above the standard model background expectation. Upper limits on the production cross section of heavy, narrow spin-1 and spin-2 resonances are derived as a function of the resonance mass, and exclusion limits on the production of W' bosons and bulk graviton particles are calculated in the framework of the heavy vector triplet model and warped extra dimensions, respectively.A search for dark matter produced in association with top quarks in proton-proton collisions at a center-of-mass energy of 13 TeV is presented. The data set used corresponds to an integrated luminosity of 35.9 fb(-1) recorded with the CMS detector at the LHC. Whereas previous searches for neutral scalar or pseudoscalar mediators considered dark matter production in association with a top quark pair only, this analysis also includes production modes with a single top quark. The results are derived from the combination of multiple selection categories that are defined to target either the single top quark or the top quark pair signature. No significant deviations with respect to the standard model predictions are observed. The results are interpreted in the context of a simplified model in which a scalar or pseudoscalar mediator particle couples to a top quark and subsequently decays into dark matter particles. Scalar and pseudoscalar mediator particles with masses below 290 and 300 GeV, respectively, are excluded at 95% confidence level, assuming a dark matter particle mass of 1 GeV and mediator couplings to fermions and dark matter particles equal to unity.Peer reviewe
Search for the pair production of light top squarks in the e(+/-)mu(-/+) final state in proton-proton collisions at root s=13 TeV
- Author
- Aarrestad TK
- Abbaneo D
- Abbiendi G
- Abbrescia M
- Abdullah WAT Wan
- Abdullin S
- Abdulsalam A
- Abercrombie D
- Abu Zeid S
- Ackert A
- Acosta D
- Acosta G
- Adam W
- Adams MR
- Adams T
- Adzic P
- Afanasiev S
- Agapitos A
- Agaras MN
- Aggleton R
- Agram J-L
- Ahmad A
- Ahmad M
- Ahmad M
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- Ahuja S
- Akbiyik M
- Akchurin N
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- Al-Bataineh A
- Albajar C
- Albergo S
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- Alhusseini M
- Ali MAB Md
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- Allen B
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- Alvarez JD Ruiz
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- Alves GA
- Alyari M
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- Ambrogi F
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- Kreczko L
- Kreis B
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- Pozzobon N
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- Ravera F
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- Re V
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- Rebello Teles P
- Redondo I
- Regnard S
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- Ruini D
- Ruiz-Jimeno A
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- Safonov A
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- Saggio A
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- Saha A
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- Sguazzoni G
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- Shopova M
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- Spiridonov A
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- Topaksu A Kayis
- Topsis-Giotis I
- Torassa E
- Toropin A
- Torres Da Silva De Araujo F
- Tos K
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- Traczyk P
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- Trevisani N
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- Troendle D
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- Tsipolitis G
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- Uzunian A
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- Vadruccio D
- Vagnerini A
- Vai I
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- Valencia F Vazquez
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- Vesztergombi G
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- Vila I
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- Vizan Garcia JM
- Vlasov E
- Vlimant JR
- Voevodina E
- Volkov A
- Volobouev I
- Vormwald B
- Vorobiev I
- Vorobyev A
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- Wissing C
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- Yu I
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- Yusli MN
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- Zorbilmez C
- Zotto P
- Zou D
- Zucchetta A
- Zumerle G
- Zuolo D
- Publication venue
- Publication date
- 01/01/2019
- Field of study
A search for the production of a pair of top squarks at the LHC is presented. This search targets a region of parameter space where the kinematics of top squark pair production and top quark pair production are very similar, because of the mass difference between the top squark and the neutralino being close to the top quark mass. The search is performed with 35.9 fb(-1) of proton-proton collisions at a centre-of-mass energy of root s = 13 TeV, collected by the CMS detector in 2016, using events containing one electron-muon pair with opposite charge. The search is based on a precise estimate of the top quark pair background, and the use of the M-T2 variable, which combines the transverse mass of each lepton and the missing transverse momentum. No excess of events is found over the standard model predictions. Exclusion limits are placed at 95% confidence level on the production of top squarks up to masses of 208 GeV for models with a mass difference between the top squark and the lightest neutralino close to that of the top quark.Peer reviewe
Search for the lepton flavor violating decay τ → 3μ in proton-proton collisions at s = 13 TeV
- Author
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- Zhemchugov E.
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- Zorbilmez C.
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- Álvarez Fernández A.
- Özçelik Ö.
- Publication venue
- Scuola Internazionale Superiore di Studi Avanzati
- Publication date
- 09/02/2021
- Field of study
Results are reported from a search for the lepton flavor violating decay τ → 3μ in proton-proton collisions at s = 13 TeV. The data sample corresponds to an integrated luminosity of 33.2 fb−1 recorded by the CMS experiment at the LHC in 2016. The search exploits τ leptons produced in both W boson and heavy-flavor hadron decays. No significant excess above the expected background is observed. An upper limit on the branching fraction B(τ → 3μ) of 8.0 x 10−8 at 90% confidence level is obtained, with an expected upper limit of 6.9 x 10−8
Search for strongly interacting massive particles generating trackless jets in proton-proton collisions at s = 13 TeV
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- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2022
- Field of study
A search for dark matter in the form of strongly interacting massive particles (SIMPs) using the CMS detector at the LHC is presented. The SIMPs would be produced in pairs that manifest themselves as pairs of jets without tracks. The energy fraction of jets carried by charged particles is used as a key discriminator to suppress efficiently the large multijet background, and the remaining background is estimated directly from data. The search is performed using proton-proton collision data corresponding to an integrated luminosity of 16.1 fb - 1 , collected with the CMS detector in 2016. No significant excess of events is observed above the expected background. For the simplified dark matter model under consideration, SIMPs with masses up to 100 GeV are excluded and further sensitivity is explored towards higher masses
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