26 research outputs found
Patrick Henry and John Jay: True Patriots and Advocates for Civil and Religious Liberty
- Author
- Publication venue
- Scholars Crossing
- Publication date
- 01/12/2021
- Field of study
Patrick Henry and John Jay had a significant impact in the founding of the United States of America as two of the principal and most influential Founders. They were also among the most public Christians of all the Founding Fathers. Their dedication in their fight for civic and religious freedom as a means to maintaining liberty was well-known. Despite these similarities, they opposed each other on most every major issue. Each envisioned different governments in which to obtain liberty and to keep the American republic. This thesis seeks to explore the differences and similarities between Henry, as a leader of the Anti-Federalists, and Jay, as a leader of the Federalists, in order to highlight some of the major issues throughout the founding period given their close religious similarity when American evangelicalism was in its infancy
Mapping genomic loci implicates genes and synaptic biology in schizophrenia
- Author
- Adams Mark
- Adolfsson Rolf
- Agartz Ingrid
- Agerbo Esben
- Al Eissa Mariam
- Albus Margot
- Alexander Madeline
- Alizadeh Behrooz Z
- Alptekin Köksal
- Als Thomas D
- Amin Farooq
- Andreassen Ole A
- Arango Celso
- Arolt Volker
- Arrojo Manuel
- Atbaşoğlu Eşref Cem
- Athanasiu Lavinia
- Atkinson Elizabeth G
- Awasthi Swapnil
- Ayub Muhammad
- Azevedo Maria Helena
- Bacanu Silviu A
- Bass Nicholas J
- Baune Bernhard T
- Begemann Martin
- Belangero Sintia Iole
- Belliveau Richard A
- Bene Judit
- Benner Christian
- Benyamin Beben
- Bergen Sarah E
- Bertolino Alessandro
- Bigdeli Tim B
- Black Donald W
- Blasi Giuseppe
- Bobes Julio
- Bonassi Stefano
- Braff David
- Bramon Elvira
- Braun Alice
- Bray Nicholas J
- Breen Gerome
- Bressan Rodrigo Affonseca
- Bromet Evelyn J
- Bruggeman Richard
- Bryois Julien
- Buccola Nancy G
- Buckley Peter F
- Buckner Randy L
- Buxbaum Joseph D
- Bybjerg-Grauholm Jonas
- Byerley William F
- Børglum Anders D
- Cahn Wiepke
- Cairns Murray J
- Calkins Monica E
- Campion Dominique
- Carr Vaughan J
- Castle David
- Catts Stanley V
- Cervilla Jorge A
- Chambert Kimberley D
- Chan Raymond CK
- Chaumette Boris
- Chen Chia-Yen
- Chen Wei J
- Cheng Wei
- Cheung Eric FC
- Chong Siow Ann
- Cichon Sven
- Cloninger C Robert
- Cohen David
- Collier David A
- Consoli Angèle
- Cordeiro Quirino
- Corvin Aiden
- Costas Javier
- Crespo-Facorro Benedicto
- Curtis Charles
- Curtis David
- Daly Mark J
- Davidson Michael
- Davis Kenneth L
- de Haan Lieuwe
- Degenhardt Franziska
- DeLisi Lynn E
- Demontis Ditte
- Dennison Charlotte A
- Dickerson Faith
- Dikeos Dimitris
- Dinan Timothy
- Djurovic Srdjan
- Domenici Enrico
- Donohoe Gary
- Duan Jubao
- Ducci Giuseppe
- Dudbridge Frank
- Ehrenreich Hannelore
- Eriksson Johan G
- Escott-Price Valentina
- Esko Tõnu
- Fanous Ayman H
- Faraone Stephen V
- Fañanás Lourdes
- Fiorentino Alessia
- Forstner Andreas
- Forti Marta Di
- Frank Josef
- Freedman Robert
- Frei Oleksandr
- Freimer Nelson B
- Fromer Menachem
- Frustaci Alessandra
- Gadelha Ary
- Galletly Cherrie
- Gandal Michael J
- Gareeva Anna
- Gawlik Micha
- Ge Tian
- Gejman Pablo V
- Gennarelli Massimo
- Genovese Giulio
- Gershon Elliot S
- Giannitelli Marianna
- Giegling Ina
- Gill Michael
- Giusti-Rodríguez Paola
- Glatt Stephen J
- Godard Stephanie
- Goldstein Jacqueline I
- Golimbet Vera
- González Peñas Javier
- González-Pinto Ana
- Gopal Srihari
- Gratten Jacob
- Green Michael F
- Greenwood Tiffany A
- Grove Jakob
- Guillin Olivier
- Gur Raquel E
- Gur Ruben C
- Gutiérrez Blanca
- Gülöksüz Sinan
- Hahn Eric
- Hakonarson Hakon
- Hall Lynsey S
- Haroutunian Vahram
- Hartmann Annette M
- Harvey Carol
- Harwood Janet C
- Hayward Caroline
- Henskens Frans A
- Herms Stefan
- Hoffmann Per
- Holmans Peter A
- Hong Kyung Sue
- Hougaard David M
- Howrigan Daniel P
- Huang Hailiang
- Hultman Christina M
- Hwu Hai-Gwo
- Hyman Steven E
- Ikeda Masashi
- Indonesia Schizophrenia Consortium
- Iwata Nakao
- Iyegbe Conrad
- Jablensky Assen V
- Joa Inge
- Julià Antonio
- Jönsson Erik G
- Kahn René S
- Kam-Thong Tony
- Kamatani Yoichiro
- Karachanak-Yankova Sena
- Kebir Oussama
- Keller Matthew C
- Kelly Brian J
- Kendler Kenneth S
- Kennedy James L
- Khrunin Andrey
- Khusnutdinova Elza
- Kim Minsoo
- Kim Sung-Wan
- Kirov George
- Klovins Janis
- Knowles James A
- Kondratiev Nikolay
- Konte Bettina
- Koopmans Frank
- Kraft Julia
- Krebs Marie-Odile
- Kubo Michiaki
- Kusumawardhani Agung
- Kuzelova-Ptackova Hana
- Kučinskas Vaidutis
- Kučinskiene Zita Ausrele
- Kähler Anna K
- Lam Max
- Landi Stefano
- Laurent-Levinson Claudine
- Lazzeroni Laura C
- Lee Jimmy
- Lee Phil H
- Legge Sophie E
- Lehrer Douglas S
- Lencer Rebecca
- Lencz Todd
- Lerer Bernard
- Levinson Douglas F
- Li Miaoxin
- Li Qingqin S
- Li Zhiqiang
- Lieberman Jeffrey
- Light Gregory A
- Limborska Svetlana
- Liu Chih-Min
- Liu Jianjun
- Loughland Carmel M
- Lubinski Jan
- Luykx Jurjen J
- Lynham Amy
- Lönnqvist Jouko
- Macek Milan
- Mackinnon Andrew
- Magnusson Patrik KE
- Magnusson Sigurdur
- Maher Brion S
- Maier Wolfgang
- Malaspina Dolores
- Malhotra Anil K
- Malhotra Dheeraj
- Mallet Jacques
- Marder Stephen R
- Marsal Sara
- Martin Alicia R
- Martorell Lourdes
- Mattheisen Manuel
- McCarley Robert W
- McCarroll Steven A
- McDonald Colm
- McGrath John J
- McIntosh Andrew
- McQuillin Andrew
- Medeiros Helena
- Meier Sandra
- Melegh Bela
- Melle Ingrid
- Menezes Paulo R
- Mesholam-Gately Raquelle I
- Metspalu Andres
- Michie Patricia T
- Milani Lili
- Milanova Vihra
- Mitjans Marina
- Molden Espen
- Molina Esther
- Molto María Dolores
- Mondelli Valeria
- Moran Jennifer L
- Moreno Carmen
- Morgan Vera A
- Morley Christopher P
- Morris Derek W
- Mors Ole
- Mortensen Preben B
- Mowry Bryan J
- Muntané Gerard
- Murphy Kieran C
- Murray Robin M
- Myin-Germeys Inez
- Müller-Myhsok Bertram
- Neale Benjamin M
- Neil Amanda L
- Nenadić Igor
- Nestadt Gerald
- Nikitina-Zake Liene
- Nimgaonkar Vishwajit
- Nordentoft Merete
- Noto Cristiano
- Nuechterlein Keith H
- Nöthen Markus M
- O'Brien Niamh Louise
- O'Donovan Michael C
- O'Neill F Anthony
- Oh Sang-Yun
- Olincy Ann
- Ophoff Roel A
- Ota Vanessa Kiyomi
- Owen Michael J
- Paciga Sara A
- Palotie Aarno
- Panagiotaropoulou Georgia
- Pantelis Christos
- Papadimitriou George N
- Pardiñas Antonio F
- Parellada Mara
- Pato Carlos N
- Pato Michele T
- Paunio Tiina
- Pellegrino Renata
- Periyasamy Sathish
- Perkins Diana O
- Petryshen Tracey L
- Pfuhlmann Bruno
- Pietiläinen Olli
- Pimm Jonathan
- Pirinen Matti
- Pocklington Andrew J
- Porteous David
- Posthuma Danielle
- Powell John
- PsychENCODE
- Psychosis Endophenotypes International Consortium
- Pulver Ann E
- Qi Ting
- Qin Shengying
- Quattrone Diego
- Quested Digby
- Radant Allen D
- Rampino Antonio
- Rapaport Mark H
- Rautanen Anna
- Reichenberg Abraham
- Richards Alexander L
- Rietschel Marcella
- Riley Brien P
- Ripke Stephan
- Rivera Margarita
- Roe Cheryl
- Roffman Joshua L
- Roth Julian
- Rothermundt Matthias
- Roussos Panos
- Rujescu Dan
- Rutten Bart PF
- Saka Meram C
- Saker-Delye Safaa
- Salomaa Veikko
- Sanders Alan R
- Sanjuan Julio
- Santoro Marcos Leite
- Savitz Adam
- Schall Ulrich
- Schizophrenia Working Group of the Psychiatric Genomics Consorti
- Schulze Thomas G
- Schwab Sibylle G
- Scott Rodney J
- Seidman Larry J
- Serretti Alessandro
- Sham Pak C
- Sharp Sally Isabel
- Shi Jianxin
- Shi Yongyong
- Sidorenko Julia
- Siever Larry J
- Sigurdsson Engilbert
- Silverman Jeremy M
- Sim Kang
- Skarabis Nora
- Slominsky Petr
- Smoller Jordan W
- So Hon-Cheong
- Sobell Janet L
- St Clair David
- Stahl Eli A
- Stain Helen J
- Steen Nils Eiel
- Stefansson Kari
- Stefánsson Hreinn
- Steixner-Kumar Agnes A
- Stone William S
- Straub Richard E
- Streit Fabian
- Strengman Eric
- Stroup T Scott
- Stögmann Elisabeth
- Subramaniam Mythily
- Sugar Catherine A
- Sullivan Patrick F
- Suvisaari Jaana
- Svrakic Dragan M
- Swerdlow Neal R
- SynGO Consortium
- Szatkiewicz Jin P
- Söderman Erik
- Ta Thi Minh Tam
- Takahashi Atsushi
- Terao Chikashi
- Thibaut Florence
- Toncheva Draga
- Tooney Paul A
- Torretta Silvia
- Tosato Sarah
- Trubetskoy Vassily
- Tsuang Debby W
- Tsuang Ming T
- Tura Gian Battista
- Turetsky Bruce I
- Vaaler Arne
- van Amelsvoort Therese
- van Os Jim
- van Winkel Ruud
- Vassos Evangelos
- Vawter Marquis P
- Veijola Juha
- Verhage Matthijs
- Vilella Elisabet
- Visscher Peter M
- Voloudakis Georgios
- Waddington John
- Walter Henrik
- Walters James TR
- Wang Shi-Heng
- Watanabe Kyoko
- Waterreus Anna
- Webb Bradley T
- Weinberger Daniel R
- Weiser Mark
- Werge Thomas
- Wildenauer Dieter B
- Williams Nigel M
- Witt Stephanie H
- Wormley Brandon K
- Wray Naomi R
- Wu Jing Qin
- Wu Yang
- Xu Shuhua
- Xu Zhida
- Yang Jian
- Yolken Robert
- Yu Xin
- Yue Weihua
- Zai Clement C
- Zeng Jian
- Zhang Wen
- Zhou Wei
- Zhu Feng
- Zimprich Fritz
- Üçok Alp
- Publication venue
- NATURE PORTFOLIO
- Publication date
- 21/04/2022
- Field of study
Schizophrenia has a heritability of 60-80%1, much of which is attributable to common risk alleles. Here, in a two-stage genome-wide association study of up to 76,755 individuals with schizophrenia and 243,649 control individuals, we report common variant associations at 287 distinct genomic loci. Associations were concentrated in genes that are expressed in excitatory and inhibitory neurons of the central nervous system, but not in other tissues or cell types. Using fine-mapping and functional genomic data, we identify 120 genes (106 protein-coding) that are likely to underpin associations at some of these loci, including 16 genes with credible causal non-synonymous or untranslated region variation. We also implicate fundamental processes related to neuronal function, including synaptic organization, differentiation and transmission. Fine-mapped candidates were enriched for genes associated with rare disruptive coding variants in people with schizophrenia, including the glutamate receptor subunit GRIN2A and transcription factor SP4, and were also enriched for genes implicated by such variants in neurodevelopmental disorders. We identify biological processes relevant to schizophrenia pathophysiology; show convergence of common and rare variant associations in schizophrenia and neurodevelopmental disorders; and provide a resource of prioritized genes and variants to advance mechanistic studies
Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders
- Author
- Adams Mark J
- Adan Roger A H
- Adolfsson Annelie Nordin
- Adolfsson Rolf
- Agartz Ingrid
- Agerbo Esben
- Akil Huda
- Albani Diego
- Alda Martin
- Alexander Madeline
- Alfredsson Lars
- Als Thomas D
- Andlauer Till F M
- Ando Tetsuya
- Andreassen Ole A
- Androutsos Christos
- Anjorin Adebayo
- Anney Richard J L
- Anttila Verneri
- Arking Dan E
- Arnold Paul D
- Arranz M. J.
- Artigas Maria Soler
- Aschauer Harald
- Asherson Philip
- Backlund Lena
- Baker Jessica H
- Baldursson Gísli
- Banaschewski Tobias
- Barr Cathy L
- Barta Csaba
- Bass Nicholas
- Bauer Michael
- Baune Bernhard T
- Begemann Martin
- Belangero Sintia
- Bellgrove Mark
- Belliveau Richard A
- Bellivier Frank
- Bencko Vladimir
- Bergen Andrew W
- Bergen Sarah E
- Berger Klaus
- Berrettini Wade H
- Bettella Francesco
- Bey Katharina
- Bienvenu O Joseph
- Biernacka Joanna M
- Binder Elisabeth B
- Birgegård Andreas
- Black Donald W
- Blackwood Douglas H R
- Boomsma Dorret I
- Bramon Elvira
- Brandt Harry
- Breen Gerome
- Brown Lawrence W
- Buccola Nancy G
- Budde Monika
- Budman Cathy
- Buitelaar Jan
- Bulik Cynthia M
- Bunney William
- Burghardt Roland
- Burmeister Margit
- Burton Christie L
- Buxbaum Joseph D
- Bybjerg-Grauholm Jonas
- Byerley William
- Byrne Enda M
- Bækvad-Hansen Marie
- Bøen Erlend
- Børglum Anders D
- Cairns Murray J
- Campion Dominique
- Carlberg Laura
- Carr Vaughan J
- Casas Miquel
- Cassina Matteo
- Castelao Enrique
- Cath Danielle
- Cerrato Felecia
- Chambert Kimberly
- Cheon Keun-Ah
- Christensen Jane H
- Churchhouse Claire
- Cichon Sven
- Ciullo Valentina
- Clarke Toni-Kim
- Clementi Maurizio
- Cloninger C Robert
- Coffey Barbara J
- Cohen David
- Coleman Jonathan R I
- Collier David A
- Collins Ryan L
- Colodro-Conde Lucía
- Cook Edwin H
- Coon Hilary
- Coppola Giovanni
- Cormand Bru
- Corvin Aiden
- Courtet Philippe
- Craddock Nicholas
- Crawford Steven
- Crosbie Jennifer
- Crow Scott
- Crowley James J
- Curtis David
- Cusi Daniele
- Czerski Piotr M
- Dale Anders M
- Dalkner Nina
- Dalsgaard Søren
- Daly Mark J
- Danner Unna N
- Dannlowski Udo
- Davis Lea K
- Davis Oliver S P
- de Geus E. J. C.
- De Rubeis Silvia
- Degenhardt Franziska
- Degortes Daniela
- DeLisi Lynn E
- Delorme Richard
- Demontis Ditte
- Denys Damiaan
- Depienne Christel
- Derks Eske M
- DeSocio Janiece E
- Di Florio Arianna
- Dick Danielle M
- Dietrich Andrea
- Dina Christian
- Direk Nese
- Docampo Elisa
- Docherty Anna R
- Domenici Enrico
- Domschke Katharina
- Donohoe Gary
- Doyle Alysa E
- Duan Jubao
- Dudbridge Frank
- Dumont Ashley
- Duncan Laramie E
- Dunn Erin C
- Eapen Valsamma
- Edenberg Howard J
- Egberts Karin
- Ehrenreich Hannelore
- Ehrlich Stefan
- Elia Josephine
- Elvsåshagen Torbjørn
- Espeseth Thomas
- Etain Bruno
- Falkai Peter
- Fanous Ayman H
- Faraone Stephen V
- Feng Yen-Chen A
- Fernandez Thomas V
- Fernández-Aranda Fernando
- Fichter Manfred M
- Fischer Sascha B
- Foo Jerome C
- Foretova Lenka
- Forstner Andreas J
- Forty Liz
- Forzan Monica
- Frank Josef
- Franke Barbara
- Freedman Robert
- Frye Mark
- Fullerton Janice M
- Gade Katrin
- Gambaro Giovanni
- Garcia-Delgar Blanca
- Gaspar Héléna A
- Ge Tian
- Gejman Pablo V
- Gelernter Joel
- Geller Daniel A
- Gershon Elliot S
- Geschwind Daniel H
- Giegling Ina
- Gilbert Donald L
- Gill Michael
- Godard Stephanie
- Goes Fernando S
- Golimbet Vera
- Gonidakis Fragiskos
- Gordon Scott D
- Gordon-Smith Katherine
- Gorwood Philip
- Grabe Hans J
- Grados Marco A
- Green Melissa J
- Greenberg Erica
- Greenwood Tiffany A
- Grice Dorothy E
- Grigoroiu-Serbanescu Maria
- Grotzinger Andrew D
- Grove Jakob
- Grünblatt Edna
- Gudmundsson Olafur O
- Guo Yiran
- Guzman-Parra José
- Haavik Jan
- Hagstrøm Julie
- Hakonarson Hakon
- Halmi Katherine A
- Hamilton Steven P
- Hanna Gregory L
- Hansen Christine S
- Hansen Thomas F
- Hartman Catharina A
- Hartmann Andreas
- Hartmann Annette M
- Hatzikotoulas Konstantinos
- Hauser Joanna
- Hautzinger Martin
- Hawi Ziarih
- Hebebrand Johannes
- Hedderly Tammy
- Heilbronner Urs
- Heiman Gary A
- Helder Sietske G
- Henskens Frans A
- Herms Stefan
- Herpertz-Dahlmann Beate
- Hervás Amaia
- Herzog Wolfgang
- Heyman Isobel
- Hinney Anke
- Hoekstra Pieter J
- Hoffmann Per
- Holland Dominic
- Holmans Peter A
- Hong Hyun Ju
- Hope Sigrun
- Horn Carsten
- Hottenga Jouke-Jan
- Hougaard David M
- Howard David
- Howrigan Daniel P
- Huang Alden
- Huang Hailiang
- Hultman Christina M
- Huyser Chaim
- Ibanez-Gomez Laura
- Ikeda Masashi
- Imgart Hartmut
- Ising Marcus
- Iwata Nakao
- Jablensky Assen V
- Jamain Stéphane
- Jiménez-Murcia Susana
- Joa Inge
- Joachim Oedegaard Ketil
- Johnson Craig
- Jones Ian
- Jones Lisa A
- Jordan Jennifer
- Julià Antonio
- Jönsson Erik G
- Kaminská Deborah
- Kandaswamy Radhika
- Kaprio Jaakko
- Karhunen Leila
- Karwautz Andreas
- Kas Martien J H
- Kaye Walter H
- Kelly Brian J
- Kelsoe John R
- Kendler Kenneth S
- Kennedy James L
- Kennedy Martin A
- Keski-Rahkonen Anna
- Khramtsova Ekaterina A
- Kim Youl-Ri
- Kim Young Key
- Kim Young-Shin
- King Robert A
- Kirov George
- Kittel-Schneider Sarah
- Klareskog Lars
- Klei Lambertus
- Kloiber Stefan
- Klump Kelly L
- Knight Jo
- Knudsen Gun Peggy S
- Kogevinas Manolis
- Koh Yun-Joo
- Koller Anna C
- Konstantinidis Anastasios
- Konte Bettina
- Kook Sodahm
- Kranzler Henry R
- Kuntsi Jonna
- Kuperman Samuel
- Ladd-Acosta Christine
- Landén Mikael
- Langley Kate
- Laurent-Levinson Claudine
- Lavebratt Catharina
- Le Hellard Stephanie
- Lee Jimmy
- Lee Phil H
- Lencz Todd
- Lerer Bernard
- Lesch Klaus-Peter
- Leung Patrick W L
- Leventhal Bennett L
- Levinson Douglas F
- Levitan Robert D
- Lewis Cathryn M
- Lewis Cathryn M
- Lewis Glyn
- Li Dong
- Li Qingqin S
- Lichtenstein Paul
- Lissowska Jolanta
- Lochner Christine
- Loo Sandra K
- Loohuis Loes M O
- Loughland Carmel M
- Lucae Susanne
- Ludolph Andrea G
- Luykx Jurjen J
- Maaser Anna
- Madruga-Garrido Marcos
- Magnusson Pall
- Magnusson Patrik K E
- Maj Mario
- Malaty Irene
- Malhotra Anil K
- Mallet Jacques
- Malt Ulrik F
- Maras Athanasios
- Marsal Sara
- Martin Alicia R
- Martin Joanna
- Martin Nicholas G
- Martinsson Lina
- Mathews Carol A
- Mattheisen Manuel
- Mayora Monica Gratacos
- Mbarek Hamdi
- McCracken James T
- McDevitt Sara
- McDonald Colm
- McElroy Susan L
- McGough James J
- McIntosh Andrew M
- McMahon Francis J
- McQuillin Andrew
- Medland Sarah E
- Meijer Inge A
- Melle Ingrid
- Metspalu Andres
- Middeldorp Christel M
- Millischer Vincent
- Mir Pablo
- Mitchell James
- Mitchell Karen S
- Mitchell Philip B
- Mitjans Marina
- Monteleone Alessio Maria
- Monteleone Palmiero
- Montgomery Grant W
- Moran Jennifer L
- Morer Astrid
- Morken Gunnar
- Morris Derek W
- Mors Ole
- Mortensen Preben B
- Mostafavi Sara
- Mowry Bryan J
- Mullins Niamh
- Munn-Chernoff Melissa A
- Murphy Kieran C
- Murphy Tara L
- Murray Robin M
- Myers Richard M
- Müller-Myhsok Bertram
- Müller-Vahl Kirsten R
- Münchau Alexander
- Naarden Allan
- Nacmias Benedetta
- Nagy Peter
- Navratilova Marie
- Neale Benjamin M
- Neale Michael C
- Nestadt Gerald
- Nestadt Paul S
- Nicolini Humberto
- Nievergelt Caroline M
- Nivard Michel G
- Nordentoft Merete
- Nurmi Erika L
- Nurnberger John I
- Nyegaard Mette
- Nyholt Dale R
- Nærland Terje
- Nöthen Markus M
- O'Donovan Michael C
- O'Neill F Anthony
- O'Toole Julie K
- Oades Robert D
- Oh Sang-Yun
- Okun Michael S
- Ophoff Roel A
- Owen Michael J
- Paciga Sara A
- Padyukov Leonid
- Palmer Duncan S
- Palotie Aarno
- Pantel Jacques
- Pantelis Christos
- Papezova Hana
- Paschou Peristera
- Pato Carlos N
- Pato Michele T
- Pedersen Carsten B
- Pedersen Marianne G
- Penninx Brenda Wjh
- Perica Vesna Boraska
- Perlis Roy H
- Perry Amy
- Peters Triinu
- Peterson Roseann E
- Petryshen Tracey L
- Pinto Dalila
- Piras Fabrizio
- Piras Federica
- Pistis Giorgio
- Pittenger Christopher
- Plessen Kerstin J
- Porteous David J
- Posthuma Danielle
- Potash James B
- Poterba Timothy
- Poulsen Jesper B
- Preisig Martin
- Pulver Ann E
- Quested Digby J
- Quiroz Jorge A
- Qvist Per
- Rabionet Raquel
- Raevuori Anu
- Ramos-Quiroga Josep Antoni
- Ramoz Nicolas
- Rehnström Karola
- Reichborn-Kjennerud Ted
- Reichenberg Abraham
- Reichert Jennifer
- Reif Andreas
- Reinbold Céline S
- Ribasés Marta
- Ricca Valdo
- Richter Margaret A
- Rietschel Marcella
- Riley Brien
- Ripke Stephan
- Rivera Margarita
- Rizzo Renata
- Roberson Mary
- Roberts Marion
- Robertson Mary
- Roeder Kathryn
- Roessner Veit
- Rohde Luis A
- Rosenthal Jacob
- Rothenberger Aribert
- Rouleau Guy A
- Rovira Paula
- Ruhrmann Stephan
- Rujescu Dan
- Rybakowski Filip
- Saemundsen Evald
- Samuels Jack F
- Sanders Alan R
- Sanders Stephan J
- Sandin Sven
- Sandor Paul
- Santangelo Susan L
- Satterstrom F Kyle
- Schachar Russell
- Schaefer Catherine
- Schall Ulrich
- Schalling Martin
- Scharf Jeremiah M
- Scherag André
- Schlögelhofer Monika
- Schmidt Ulrike
- Schofield Peter R
- Schulte Eva C
- Schulze Thomas G
- Schwab Sibylle G
- Scott Laura J
- Scott Rodney J
- Seitz Jochen
- Serretti Alessandro
- Sham Pak C
- Shi Jianxin
- Shin Eun-Young
- Sigurdsson Engilbert
- Silverman Jeremy M
- Sim Kang
- Singer Harvey
- Slachtova Lenka
- Slof-Op't Landt Margarita C T
- Slopien Agnieszka
- Smeland Olav B
- Smith Daniel J
- Smoller Jordan W
- Song Dong-Ho
- Song Jungeun
- Sorbi Sandro
- Southam Lorraine
- Spalletta Gianfranco
- St Pourcain Beate
- Stahl Eli A
- Stefansson Hreinn
- Stefansson Kari
- Stein Dan J
- Stein Murray B
- Steinberg Stacy
- Steixner Agnes A
- Stewart S Evelyn
- Storch Eric A
- Stordal Eystein
- Stranger Barbara
- Streit Fabian
- Strober Michael
- Strohmaier Jana
- Stuhrmann Manfred
- Sullivan Patrick F
- Sutcliffe James S
- Sánchez-Mora Cristina
- Talkowski Michael E
- Tarnok Zsanett
- Thomson Pippa A
- Thorgeirsson Thorgeir E
- Thornton Laura M
- Tiemeier Henning
- Tischfield Jay A
- Tooney Paul A
- Tortorella Alfonso
- Tozzi Federica
- Treasure Janet
- Treutlein Jens
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- Tübing Jennifer
- Uher Rudolf
- Vaaler Arne E
- van der Auwera Sandra
- van Elburg Annemarie A
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- Vieta Eduard
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- Weiser Mark
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- Werge Thomas
- Wichmann H-Erich
- Wildenauer Dieter B
- Williams Nigel M
- Willsey A Jeremy
- Witt Stephanie H
- Won Hyejung
- Woods Martin
- Woodside D Blake
- Worbe Yulia
- Wormley Brandon K
- Wray Naomi R
- Yu Dongmei
- Zai Clement C
- Zai Gwyneth
- Zandi Peter
- Zayats Tetyana
- Zeggini Eleftheria
- Zerwas Stephanie
- Zhang Fuquan
- Zheutlin Amanda
- Zhu Zhaozhong
- Zinner Samuel H
- Zipfel Stephan
- Publication venue
- Publication date
- 01/01/2019
- Field of study
Genetic influences on psychiatric disorders transcend diagnostic boundaries, suggesting substantial pleiotropy of contributing loci. However, the nature and mechanisms of these pleiotropic effects remain unclear. We performed analyses of 232,964 cases and 494,162 controls from genome-wide studies of anorexia nervosa, attention-deficit/hyper-activity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, and Tourette syndrome. Genetic correlation analyses revealed a meaningful structure within the eight disorders, identifying three groups of inter-related disorders. Meta-analysis across these eight disorders detected 109 loci associated with at least two psychiatric disorders, including 23 loci with pleiotropic effects on four or more disorders and 11 loci with antagonistic effects on multiple disorders. The pleiotropic loci are located within genes that show heightened expression in the brain throughout the lifespan, beginning prenatally in the second trimester, and play prominent roles in neurodevelopmental processes. These findings have important implications for psychiatric nosology, drug development, and risk prediction.Peer reviewe
Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes
- Author
- Adolfsson Rolf
- Agartz Ingrid
- Agerbo Esben
- Akil Huda
- Albani Diego
- Albus Margot
- Alda Martin
- Alexander Madeline
- Alliey-Rodriguez Ney
- Als Thomas D
- Amin Farooq
- Andreassen Ole A
- Anjorin Adebayo
- Arranz Maria J
- Awasthi Swapnil
- Bacanu Silviu A
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- Baekvad-Hansen Marie
- Bakker Steven
- Band Gavin
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- Barroso Ines
- Bass Nicholas
- Bauer Michael
- Baune Bernhard T
- Begemann Martin
- Bellenguez Celine
- Bellivier Frank
- Bender Stephan
- Bene Judit
- Bergen Sarah E
- Berrettini Wade H
- Bevilacqua Elizabeth
- Biernacka Joanna M
- Bigdeli Tim B
- Black Donald W
- Blackburn Hannah
- Blackwell Jenefer M
- Blackwood Douglas HR
- Boehnke Michael
- Boks Marco
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- Bramon Elvira
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- Buckner Randy L
- Budde Monika
- Bulik-Sullivan Brendan
- Bumpstead Suzannah J
- Bunney William
- Burmeister Margit
- Buxbaum Joseph D
- Bybjerg-Grauholm Jonas
- Byerley William
- Cahn Wiepke
- Cai Guiqing
- Cairns Murray J
- Campion Dominique
- Cantor Rita M
- Carr Vaughan J
- Carrera Noa
- Casas Juan P
- Casas Miquel
- Case-Control Wellcome Trust
- Catts Stanley V
- Cervantes Pablo
- Chambert Kimberley D
- Chan Raymond CK
- Charney Alexander W
- Chen Eric YH
- Chen Ronald YL
- Cheng Wei
- Cheung Eric FC
- Chong Siow Ann
- Cichon Sven
- Clarke Toni-Kim
- Cloninger C Robert
- Cohen David
- Cohen Nadine
- Coleman Jonathan RI
- Collier David A
- Consortium Psychiat Genomics
- Consortium Psychiat Genomics
- Cormican Paul
- Corvin Aiden
- Coryell William
- Craddock Nicholas
- Craig David W
- Crespo-Facorro Benedicto
- Crowley James J
- Cruceanu Cristiana
- Cuellar-Barboza Alfredo B
- Curtis David
- Czerski Piotr M
- Dale Anders M
- Daly Mark J
- Dannlowski Udo
- Darvasi Ariel
- Davidson Michael
- Davis Kenneth L
- de Haan Lieuwe
- de Leeuw Christiaan A
- Degenhardt Franziska
- Del Favero Jurgen
- DeLisi Lynn E
- Deloukas Panos
- Demontis Ditte
- DePaulo J Raymond
- Di Florio Arianna
- di Forti Marta
- Dikeos Dimitris
- Dinan Timothy
- Djurovic Srdjan
- Dobbyn Amanda L
- Domenici Enrico
- Donnelly Peter
- Donohoe Gary
- Drapeau Elodie
- Dronov Serge
- Duan Jubao
- Dudbridge Frank
- Duncanson Audrey
- Edenberg Howard
- Edkins Sarah
- Ehrenreich Hannelore
- Eichhammer Peter
- Elvsashagen Torbjorn
- Eriksson Johan
- Escott-Price Valentina
- Esko Tonu
- Essioux Laurent
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- Fan Chun Chieh
- Fanous Ayman H
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- Webb Brad-Ley T
- Weickert Cynthia Shannon
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- Weisbrod Matthias
- Weiser Mark
- Werge Thomas
- Weston Paul
- Whittaker Pamela
- Widaa Sara
- Wiersma Durk
- Wildenauer Dieter B
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- Wong Emily HM
- Wood Nicholas W
- Wormley Brandon K
- Wray Naomi R
- Wu Jing Qin
- Xi Simon
- Xu Wei
- Young Allan H
- Zai Clement C
- Zandi Peter
- Zhang Peng
- Zheng Xuebin
- Zimprich Fritz
- Zollner Sebastian
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2018
- Field of study
publisher: Elsevier articletitle: Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes journaltitle: Cell articlelink: https://doi.org/10.1016/j.cell.2018.05.046 content_type: article copyright: © 2018 Elsevier Inc
Multiorgan MRI findings after hospitalisation with COVID-19 in the UK (C-MORE): a prospective, multicentre, observational cohort study
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- Yasmin S
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- Zawia Amira
- Zeidan Lisa
- Zhao Bang
- Zheng Bang
- Zongo O.
- Publication venue
- Elsevier
- Publication date
- 22/09/2023
- Field of study
Introduction:
The multiorgan impact of moderate to severe coronavirus infections in the post-acute phase is still poorly understood. We aimed to evaluate the excess burden of multiorgan abnormalities after hospitalisation with COVID-19, evaluate their determinants, and explore associations with patient-related outcome measures.
Methods:
In a prospective, UK-wide, multicentre MRI follow-up study (C-MORE), adults (aged ≥18 years) discharged from hospital following COVID-19 who were included in Tier 2 of the Post-hospitalisation COVID-19 study (PHOSP-COVID) and contemporary controls with no evidence of previous COVID-19 (SARS-CoV-2 nucleocapsid antibody negative) underwent multiorgan MRI (lungs, heart, brain, liver, and kidneys) with quantitative and qualitative assessment of images and clinical adjudication when relevant. Individuals with end-stage renal failure or contraindications to MRI were excluded. Participants also underwent detailed recording of symptoms, and physiological and biochemical tests. The primary outcome was the excess burden of multiorgan abnormalities (two or more organs) relative to controls, with further adjustments for potential confounders. The C-MORE study is ongoing and is registered with ClinicalTrials.gov, NCT04510025.
Findings:
Of 2710 participants in Tier 2 of PHOSP-COVID, 531 were recruited across 13 UK-wide C-MORE sites. After exclusions, 259 C-MORE patients (mean age 57 years [SD 12]; 158 [61%] male and 101 [39%] female) who were discharged from hospital with PCR-confirmed or clinically diagnosed COVID-19 between March 1, 2020, and Nov 1, 2021, and 52 non-COVID-19 controls from the community (mean age 49 years [SD 14]; 30 [58%] male and 22 [42%] female) were included in the analysis. Patients were assessed at a median of 5·0 months (IQR 4·2–6·3) after hospital discharge. Compared with non-COVID-19 controls, patients were older, living with more obesity, and had more comorbidities. Multiorgan abnormalities on MRI were more frequent in patients than in controls (157 [61%] of 259 vs 14 [27%] of 52; p<0·0001) and independently associated with COVID-19 status (odds ratio [OR] 2·9 [95% CI 1·5–5·8]; padjusted=0·0023) after adjusting for relevant confounders. Compared with controls, patients were more likely to have MRI evidence of lung abnormalities (p=0·0001; parenchymal abnormalities), brain abnormalities (p<0·0001; more white matter hyperintensities and regional brain volume reduction), and kidney abnormalities (p=0·014; lower medullary T1 and loss of corticomedullary differentiation), whereas cardiac and liver MRI abnormalities were similar between patients and controls. Patients with multiorgan abnormalities were older (difference in mean age 7 years [95% CI 4–10]; mean age of 59·8 years [SD 11·7] with multiorgan abnormalities vs mean age of 52·8 years [11·9] without multiorgan abnormalities; p<0·0001), more likely to have three or more comorbidities (OR 2·47 [1·32–4·82]; padjusted=0·0059), and more likely to have a more severe acute infection (acute CRP >5mg/L, OR 3·55 [1·23–11·88]; padjusted=0·025) than those without multiorgan abnormalities. Presence of lung MRI abnormalities was associated with a two-fold higher risk of chest tightness, and multiorgan MRI abnormalities were associated with severe and very severe persistent physical and mental health impairment (PHOSP-COVID symptom clusters) after hospitalisation.
Interpretation:
After hospitalisation for COVID-19, people are at risk of multiorgan abnormalities in the medium term. Our findings emphasise the need for proactive multidisciplinary care pathways, with the potential for imaging to guide surveillance frequency and therapeutic stratification
Measurement of the charge asymmetry in top-quark pair production in the lepton-plus-jets final state in pp collision data at s=8TeV with the ATLAS detector
- Author
- Abbott Brad
- Abdallah Jalal
- Abdinov Ovsat
- Aben Rosemarie
- Abolins Maris
- AbouZeid Ossama
- Abramowicz Halina
- Abreu Henso
- Abreu Ricardo
- Abulaiti Yiming
- Acharya Bobby Sami
- Adamczyk Leszek
- Adams David
- Adelman Jahred
- Adomeit Stefanie
- Adye Tim
- Affolder Tony
- Agatonovic-Jovin Tatjana
- Agricola Johannes
- Aguilar-Saavedra Juan Anton
- Ahlen Steven
- Ahmadov Faig
- Aielli Giulio
- Akerstedt Henrik
- Akimov Andrei
- Alberghi Gian Luigi
- Albert Justin
- Albrand Solveig
- Alconada Verzini Maria Jose
- Aleksa Martin
- Aleksandrov Igor
- Alexa Calin
- Alexander Gideon
- Alexopoulos Theodoros
- Alhroob Muhammad
- Alimonti Gianluca
- Alio Lion
- Alison John
- Alkire Steven Pat
- Allbrooke Benedict
- Allport Phillip
- Aloisio Alberto
- Alonso Alejandro
- Alonso Francisco
- Alpigiani Cristiano
- Altheimer Andrew Dav
- Alvarez Gonzalez Barbara
- Alviggi Mariagrazi
- Amadio Brian Thom
- Amako Katsuya
- Amaral Coutinho Yara
- Amelung Christoph
- Amidei Dante
- Amor Dos Santos Susana Pat
- Amorim Antonio
- Amoroso Simone
- Amram Nir
- Amundsen Glenn
- Anastopoulos Christos
- Ancu Lucian Ste
- Andari Nansi
- Andeen Timothy
- Anders Christoph
- Anders Gabriel
- Anders John Kenne
- Anderson Kelby
- Andreazza Attilio
- Andrei George Vic
- Angelidakis Stylianos
- Angelozzi Ivan
- Anger Philipp
- Angerami Aaron
- Anghinolfi Francis
- Anisenkov Alexey
- Anjos Nuno
- Annovi Alberto
- Antonelli Mario
- Antonov Alexey
- Antos Jaroslav
- Anulli Fabio
- Aoki Masato
- Aperio Bella Ludovica
- Arabidze Giorgi
- Arai Yasuo
- Araque Juan Pedro
- Arce Ayana
- Arduh Francisco
- Arguin Jean-Franc
- Argyropoulos Spyridon
- Arik Metin
- Armbruster Aaron Jame
- Arnaez Olivier
- Arnold Hannah
- Arratia Miguel
- Arslan Ozan
- Artamonov Andrei
- Artoni Giacomo
- Asai Shoji
- Asbah Nedaa
- Ashkenazi Adi
- Asquith Lily
- Assamagan Ketevi
- Astalos Robert
- Atkinson Markus
- Atlay Naim Bora
- Augsten Kamil
- Aurousseau Mathieu
- Avolio Giuseppe
- Axen Bradley
- Ayoub Mohamad Ka
- Azuelos Georges
- Baak Max
- Baas Alessandra
- Baca Matthew Jo
- Bacci Cesare
- Bachacou Henri
- Bachas Konstantin
- Backes Moritz
- Backhaus Malte
- Bagiacchi Paolo
- Bagnaia Paolo
- Bai Yu
- Bain Travis
- Baines John
- Baker Oliver Kei
- Baldin Evgenii
- Balek Petr
- Balestri Thomas
- Balli Fabrice
- Balunas William Ke
- Banas Elzbieta
- Banerjee Swagato
- Bannoura Arwa A E
- Barak Liron
- Barberio Elisabetta
- Barberis Dario
- Barbero Marlon
- Barillari Teresa
- Barisonzi Marcello
- Barklow Timothy
- Barlow Nick
- Barnes Sarah Loui
- Barnett Bruce
- Barnett Michael
- Barnovska Zuzana
- Baroncelli Antonio
- Barone Gaetano
- Barr Alan
- Barreiro Guimarães da Costa João
- Barreiro Fernando
- Barros do Vale Maria Alin
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- Barton Adam Edwar
- Bartos Pavol
- Basalaev Artem
- Bassalat Ahmed
- Basye Austin
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- Batley Richard
- Battaglia Marco
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- Beccherle Roberto
- Bechtle Philip
- Beck Hans Peter
- Becker Kathrin
- Becker Maurice
- Beckingham Matthew
- Becot Cyril
- Beddall Andrew
- Beddall Ayda
- Bednyakov Vadim
- Bee Christophe
- Beemster Lars
- Beermann Thomas
- Begel Michael
- Behr Janna Kath
- Belanger-Champagne Camille
- Bell William
- Bella Gideon
- Bellagamba Lorenzo
- Bellerive Alain
- Bellomo Massimilia
- Belotskiy Konstantin
- Beltramello Olga
- Benary Odette
- Benchekroun Driss
- Bender Michael
- Bendtz Katarina
- Benekos Nektarios
- Benhammou Yan
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- Beringer Jürg
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- Bertsche Carolyn
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- Bessidskaia Bylund Olga
- Bessner Martin Flo
- Besson Nathalie
- Betancourt Christophe
- Bethke Siegfried
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- Bhimji Wahid
- Bianchi Riccardo-M
- Bianchini Louis
- Bianco Michele
- Biebel Otmar
- Biedermann Dustin
- Bieniek Stephen Pa
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- Biglietti Michela
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- Bilokon Halina
- Bindi Marcello
- Binet Sebastien
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- Black James
- Black Kevin
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- Blanchard Jean-Bapti
- Blanco Jacobo Eze
- Blazek Tomas
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- Blocker Craig
- Blum Walter
- Blumenschein Ulrike
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- Bobrovnikov Victor
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- Bocci Andrea
- Bock Christophe
- Boehler Michael
- Bogaerts Joannes An
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- Bogdanchikov Alexander
- Bohm Christian
- Boisvert Veronique
- Bold Tomasz
- Boldea Venera
- Boldyrev Alexey
- Bomben Marco
- Bona Marcella
- Boonekamp Maarten
- Borisov Anatoly
- Borissov Guennadi
- Borroni Sara
- Bortfeldt Jonathan
- Bortolotto Valerio
- Bos Kors
- Boscherini Davide
- Bosman Martine
- Boudreau Joseph
- Bouffard Julian
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- Bourdarios Claire
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- Brau James
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- Breaden Madden William Dm
- Brendlinger Kurt
- Brennan Amelia Jea
- Brenner Lydia
- Brenner Richard
- Bressler Shikma
- Bristow Timothy Mi
- Britton Dave
- Britzger Daniel
- Brochu Frederic
- Brock Ian
- Brock Raymond
- Bronner Johanna
- Brooijmans Gustaaf
- Brooks Timothy
- Brooks William
- Brosamer Jacquelyn
- Brost Elizabeth
- Bruckman de Renstrom Pawel
- Bruncko Dusan
- Bruneliere Renaud
- Bruni Alessia
- Bruni Graziano
- Bruschi Marco
- Bruscino Nello
- Bryngemark Lene
- Buanes Trygve
- Buat Quentin
- Buchholz Peter
- Buckley Andrew
- Buda Stelian Io
- Budagov Ioulian
- Buehrer Felix
- Bugge Lars
- Bugge Magnar Kop
- Bulekov Oleg
- Bullock Daniel
- Burckhart Helfried
- Burdin Sergey
- Burgard Carsten Da
- Burghgrave Blake
- Burke Stephen
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- Bussey Peter
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- Butt Aatif Imti
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- Butterworth Jonathan
- Butti Pierfrance
- Buttinger William
- Buzatu Adrian
- Buzykaev Aleksey
- Büscher Daniel
- Büscher Volker
- Cabrera Urbán Susana
- Caforio Davide
- Cairo Valentina
- Cakir Orhan
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- Calafiura Paolo
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- Calderini Giovanni
- Calfayan Philippe
- Caloba Luiz
- Calvet David
- Calvet Samuel
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- Cameron David
- Caminal Armadans Roger
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- Capua Marcella
- Caputo Regina
- Carbone Ryne Micha
- Cardarelli Roberto
- Cardillo Fabio
- Carli Tancredi
- Carlino Gianpaolo
- Carminati Leonardo
- Caron Sascha
- Carquin Edson
- Carrillo-Montoya German D
- Carter Janet
- Carvalho João
- Casadei Diego
- Casado Maria Pila
- Casolino Mirkoanton
- Castaneda-Miranda Elizabeth
- Castelli Angelanton
- Castillo Gimenez Victoria
- Castro Nuno Filip
- Catastini Pierluigi
- Catinaccio Andrea
- Catmore James
- Cattai Ariella
- Caudron Julien
- Cavaliere Viviana
- Cavalli Donatella
- Cavalli-Sforza Matteo
- Cavasinni Vincenzo
- Ceradini Filippo
- Cerio Benjamin
- Cerny Karel
- Cerri Alessandro
- Cerrito Lucio
- Cerutti Fabio
- Cerv Matevz
- Cervelli Alberto
- Cetin Serkant Al
- Chafaq Aziz
- Chakraborty Dhiman
- Chalupkova Ina
- Chan Yat Long
- Chang Philip
- Chapman John Derek
- Charlton Dave
- Chau Chav Chhiv
- Chavez Barajas Carlos Alb
- Cheatham Susan
- Chegwidden Andrew
- Chekanov Sergei
- Chekulaev Sergey
- Chelkov Gueorgui
- Chelstowska Magda Anna
- Chen Chunhui
- Chen Hucheng
- Chen Karen
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- Edson William
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- Grabas Herve Mari
- Graber Lars
- Grabowska-Bold Iwona
- Gradin Per Olov J
- Grafström Per
- Gramling Johanna
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- Grefe Christian
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- Grenier Philippe
- Griffiths Justin
- Grillo Alexander
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- Grinstein Sebastian
- Gris Philippe L
- Grivaz Jean-Franc
- Grohs Johannes P
- Grohsjean Alexander
- Gross Eilam
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- Harrison Paul Frase
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- Hasegawa Makoto
- Hasegawa Yoji
- Hasib A
- Hassani Samira
- Haug Sigve
- Hauser Reiner
- Hauswald Lorenz
- Havranek Miroslav
- Hawkes Christophe
- Hawkings Richard Jo
- Hawkins Anthony Da
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- Hays Chris
- Hays Jonathan M
- Hayward Helen
- Haywood Stephen
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- Henkelmann Steffen
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- Hernández Jiménez Yesenia
- Herten Gregor
- Hertenberger Ralf
- Hervas Luis
- Hesketh Gavin Gran
- Hessey Nigel
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- Johansson Per
- Johns Kenneth
- Johnson William Jo
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- Jones Roger
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- Karakostas Konstantin
- Karamaoun Andrew
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- Kareem Mohammad J
- Karentzos Efstathios
- Karnevskiy Mikhail
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- Kasahara Kota
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- Kourkoumeli-Charalampidi Athina
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- Köneke Karsten
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- Laycock Paul
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- LeCompte Thomas
- Ledroit-Guillon Fabienne A
- Lee Claire Ale
- Lee Lawrence
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- Lefebvre Guillaume
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- Legger Federica
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- Loginov Andrey
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- Willocq Stephane
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- Wingerter-Seez Isabelle
- Winklmeier Frank
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- Wittgen Matthias
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- Yabsley Bruce
- Yacoob Sahal
- Yakabe Ryota
- Yamada Miho
- Yamaguchi Daiki
- Yamaguchi Yohei
- Yamamoto Akira
- Yamamoto Shimpei
- Yamanaka Takashi
- Yamauchi Katsuya
- Yamazaki Yuji
- Yan Zhen
- Yang Haijun
- Yang Hongtao
- Yang Yi
- Yao Weiming
- Yap Yee Chinn
- Yasu Yoshiji
- Yatsenko Elena
- Yau Wong Kaven Henr
- Ye Jingbo
- Ye Shuwei
- Yeletskikh Ivan
- Yen Andy L
- Yildirim Eda
- Yorita Kohei
- Yoshida Rikutaro
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- Yu Jaehoon
- Yu Jiaming
- Yu Jie
- Yuan Li
- Yuen Stephanie
- Yurkewicz Adam
- Yusuff Imran
- Zabinski Bartlomiej
- Zaidan Remi
- Zaitsev Alexander
- Zalieckas Justas
- Zaman Aungshuman
- Zambito Stefano
- Zanello Lucia
- Zanzi Daniele
- Zeitnitz Christian
- Zeman Martin
- Zemla Andrzej
- Zeng Qi
- Zengel Keith
- Zenin Oleg
- Zerwas Dirk
- Zhang Dongliang
- Zhang Fangzhou
- Zhang Guangyi
- Zhang Huijun
- Zhang Jinlong
- Zhang Lei
- Zhang Ruiqi
- Zhang Xueyao
- Zhang Zhiqing
- Zhao Xiandong
- Zhao Yongke
- Zhao Zhengguo
- Zhemchugov Alexey
- Zhong Jiahang
- Zhou Bing
- Zhou Chen
- Zhou Lei
- Zhou Li
- Zhou Mingliang
- Zhou Ning
- Zhu Cheng Guan
- Zhu Hongbo
- Zhu Junjie
- Zhu Yingchun
- Zhuang Xuai
- Zhukov Konstantin
- Zibell Andre
- Zieminska Daria
- Zimine Nikolai
- Zimmermann Christoph
- Zimmermann Stephanie
- Zinonos Zinonas
- Zinser Markus
- Ziolkowski Michael
- Zobernig Georg
- Zoccoli Antonio
- zur Nedden Martin
- Zurzolo Giovanni
- Zwalinski Lukasz
- Åkesson Torsten Pa
- Åsman Barbro
- Ženiš Tibor
- Živković Lidija
- Άlvarez Piqueras Damián
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 19/02/2016
- Field of study
ATLAS Run 1 searches for direct pair production of third-generation squarks at the Large Hadron Collider
- Author
- Abbott Brad
- Abdallah Jalal
- Abdinov Ovsat
- Aben Rosemarie
- Abolins Maris
- AbouZeid Ossama
- Abramowicz Halina
- Abreu Henso
- Abreu Ricardo
- Abulaiti Yiming
- Acharya Bobby Sami
- Adamczyk Leszek
- Adams David
- Adelman Jahred
- Adomeit Stefanie
- Adye Tim
- Affolder Tony
- Agatonovic-Jovin Tatjana
- Agricola Johannes
- Aguilar-Saavedra Juan Anton
- Ahlen Steven
- Ahmadov Faig
- Aielli Giulio
- Akerstedt Henrik
- Akimov Andrei
- Alberghi Gian Luigi
- Albert Justin
- Albrand Solveig
- Alconada Verzini Maria Jose
- Aleksa Martin
- Aleksandrov Igor
- Alexa Calin
- Alexander Gideon
- Alexopoulos Theodoros
- Alhroob Muhammad
- Alimonti Gianluca
- Alio Lion
- Alison John
- Alkire Steven Pat
- Allbrooke Benedict
- Allport Phillip
- Aloisio Alberto
- Alonso Alejandro
- Alonso Francisco
- Alpigiani Cristiano
- Altheimer Andrew Dav
- Alvarez Gonzalez Barbara
- Alviggi Mariagrazi
- Amadio Brian Thom
- Amako Katsuya
- Amaral Coutinho Yara
- Amelung Christoph
- Amidei Dante
- Amor Dos Santos Susana Pat
- Amorim Antonio
- Amoroso Simone
- Amram Nir
- Amundsen Glenn
- Anastopoulos Christos
- Ancu Lucian Ste
- Andari Nansi
- Andeen Timothy
- Anders Christoph
- Anders Gabriel
- Anders John Kenne
- Anderson Kelby
- Andreazza Attilio
- Andrei George Vic
- Angelidakis Stylianos
- Angelozzi Ivan
- Anger Philipp
- Angerami Aaron
- Anghinolfi Francis
- Anisenkov Alexey
- Anjos Nuno
- Annovi Alberto
- Antonelli Mario
- Antonov Alexey
- Antos Jaroslav
- Anulli Fabio
- Aoki Masato
- Aperio Bella Ludovica
- Arabidze Giorgi
- Arai Yasuo
- Araque Juan Pedro
- Arce Ayana
- Arduh Francisco
- Arguin Jean-Franc
- Argyropoulos Spyridon
- Arik Metin
- Armbruster Aaron Jame
- Arnaez Olivier
- Arnal Vanessa
- Arnold Hannah
- Arratia Miguel
- Arslan Ozan
- Artamonov Andrei
- Artoni Giacomo
- Asai Shoji
- Asbah Nedaa
- Ashkenazi Adi
- Asquith Lily
- Assamagan Ketevi
- Astalos Robert
- Atkinson Markus
- Atlay Naim Bora
- Auerbach Benjamin
- Augsten Kamil
- Aurousseau Mathieu
- Avolio Giuseppe
- Axen Bradley
- Ayoub Mohamad Ka
- Azuelos Georges
- Baak Max
- Baas Alessandra
- Baca Matthew Jo
- Bacci Cesare
- Bachacou Henri
- Bachas Konstantin
- Backes Moritz
- Backhaus Malte
- Bagiacchi Paolo
- Bagnaia Paolo
- Bai Yu
- Bain Travis
- Baines John
- Baker Oliver Kei
- Baldin Evgenii
- Balek Petr
- Balestri Thomas
- Balli Fabrice
- Banas Elzbieta
- Banerjee Swagato
- Bannoura Arwa A E
- Bansil Hardeep Si
- Barak Liron
- Barberio Elisabetta
- Barberis Dario
- Barbero Marlon
- Barillari Teresa
- Barisonzi Marcello
- Barklow Timothy
- Barlow Nick
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- Barnett Bruce
- Barnett Michael
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- Baroncelli Antonio
- Barone Gaetano
- Barr Alan
- Barreiro Guimarães da Costa João
- Barreiro Fernando
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- Bartoldus Rainer
- Barton Adam Edwar
- Bartos Pavol
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- Bassalat Ahmed
- Basye Austin
- Bates Richard
- Batista Santiago J
- Batley Richard
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- Bauer Florian
- Bawa Harinder S
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- Beattie Michael Da
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- Bianchini Louis
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- Blazek Tomas
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- Carquin Edson
- Carrillo-Montoya German D
- Carter Janet
- Carvalho João
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- Casado Maria Pila
- Casolino Mirkoanton
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- Chafaq Aziz
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- Chalupkova Ina
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- Cheu Elliott
- Chevalier Laurent
- Chiarella Vitaliano
- Chiarelli Giorgio
- Childers John Taylo
- Chiodini Gabriele
- Chisholm Andrew
- Chislett Rebecca Th
- Chitan Adrian
- Chizhov Mihail
- Choi Kyungeon
- Chouridou Sofia
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- Chromek-Burckhart Doris
- Chudoba Jiri
- Chuinard Annabelle
- Chwastowski Janusz
- Chytka Ladislav
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- Ciubancan Mihai
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- Clark Brian Lee
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- Cleland Bill
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- Cochran James H
- Coffey Laurel
- Cogan Joshua God
- Colasurdo Luca
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- Cummings Jane
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- Weingarten Jens
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- Wiik-Fuchs Liv Antje
- Wildauer Andreas
- Wilkens Henric Geo
- Williams Hugh
- Williams Sarah
- Willis Christophe
- Willocq Stephane
- Wilson Alan
- Wilson John
- Wingerter-Seez Isabelle
- Winklmeier Frank
- Winter Benedict T
- Wittgen Matthias
- Wittkowski Josephine
- Wollstadt Simon Jako
- Wolter Marcin Wla
- Wolters Helmut
- Wosiek Barbara
- Wotschack Jorg
- Woudstra Martin
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- Wu Sau Lan
- Wu Xin
- Wu Yusheng
- Wyatt Terry Rich
- Wynne Benjamin
- Xella Stefania
- Xu Da
- Xu Lailin
- Yabsley Bruce
- Yacoob Sahal
- Yakabe Ryota
- Yamada Miho
- Yamaguchi Yohei
- Yamamoto Akira
- Yamamoto Shimpei
- Yamanaka Takashi
- Yamauchi Katsuya
- Yamazaki Yuji
- Yan Zhen
- Yang Haijun
- Yang Hongtao
- Yang Yi
- Yao Weiming
- Yasu Yoshiji
- Yatsenko Elena
- Yau Wong Kaven Henr
- Ye Jingbo
- Ye Shuwei
- Yeletskikh Ivan
- Yen Andy L
- Yildirim Eda
- Yorita Kohei
- Yoshida Rikutaro
- Yoshihara Keisuke
- Young Charles
- Young Christophe
- Youssef Saul
- Yu David Ren-
- Yu Jaehoon
- Yu Jiaming
- Yu Jie
- Yuan Li
- Yuen Stephanie
- Yurkewicz Adam
- Yusuff Imran
- Zabinski Bartlomiej
- Zaidan Remi
- Zaitsev Alexander
- Zalieckas Justas
- Zaman Aungshuman
- Zambito Stefano
- Zanello Lucia
- Zanzi Daniele
- Zeitnitz Christian
- Zeman Martin
- Zemla Andrzej
- Zengel Keith
- Zenin Oleg
- Zerwas Dirk
- Zhang Dongliang
- Zhang Fangzhou
- Zhang Huijun
- Zhang Jinlong
- Zhang Lei
- Zhang Ruiqi
- Zhang Xueyao
- Zhang Zhiqing
- Zhao Xiandong
- Zhao Yongke
- Zhao Zhengguo
- Zhemchugov Alexey
- Zhong Jiahang
- Zhou Bing
- Zhou Chen
- Zhou Lei
- Zhou Li
- Zhou Ning
- Zhu Cheng Guan
- Zhu Hongbo
- Zhu Junjie
- Zhu Yingchun
- Zhuang Xuai
- Zhukov Konstantin
- Zibell Andre
- Zieminska Daria
- Zimine Nikolai
- Zimmermann Christoph
- Zimmermann Stephanie
- Zinonos Zinonas
- Zinser Markus
- Ziolkowski Michael
- Zobernig Georg
- Zoccoli Antonio
- zur Nedden Martin
- Zurzolo Giovanni
- Zwalinski Lukasz
- Åkesson Torsten Pa
- Åsman Barbro
- Ženiš Tibor
- Živković Lidija
- Άlvarez Piqueras Damián
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 29/10/2015
- Field of study
Composing as an “essentialist”?: New directions for feminist composition theories
- Author
- _____
- _____
- _____
- _____
- _____
- Alcoff Linda
- Annas Pamela J.
- Bartholomae David
- Batson Lorie Goodman
- Belenky Mary
- Belenky Mary Held
- Berlin James A.
- Bizzell Patricia
- Carby Hazel
- Chodorow Nancy
- Devoney Looser
- Elbow Peter
- Faigley Lester
- Freire Paolo
- Fuss Diana
- Gallop Jane
- Gilligan Carol
- Gore Jennifer
- Greenwood Cynthia
- Jarratt Susan
- Lather Parti
- Rich Adrienne
- Riley Denise
- Ritchie Joy S.
- Spivak Gayatri Chakravorty
- Tedesco Janis
- Worsham Lynn
- Publication venue
- 'Informa UK Limited'
- Publication date
- Field of study
The Antiquity and Significance of Effigies and Representational Art in Southern California Prehistory
- Author
- Apodaca Paul
- Bright William
- Byrd Brian F.
- Cameron Constance
- Cameron Constance
- Cameron Constance
- Cassidy Jim
- Cottrell Marie G.
- Davis James T.
- de Cessac
- Desautels Nancy A.
- Drover Christopher E.
- Drover Christopher E.
- Eberhart Hal
- Erlandson Jon M.
- Fitzgerald Richard T.
- Fitzgerald Richard T.
- Gamble Lynn H.
- Gamble Lynn H.
- Gamble Lynn H.
- Gilreath A. J
- Goldberg Carol
- Golla Victor
- Greenwood Roberta S.
- Greenwood Roberta S.
- Greenwood Roberta S.
- Harrington John P.
- Harrison W
- Harrison W. M
- Herring Alika K.
- Hoover Robert L.
- Hoover Robert L.
- Howard William C.
- Hudson Travis
- Jenkins Dennis L.
- Jones Terry L.
- Jones Terry L.
- Kennett Douglas J.
- Koerper Henry C.
- Koerper Henry C.
- Koerper Henry C.
- Kroeber Alfred L.
- Lee Georgia
- Lee Georgia
- Lopez Robert
- Meighan Clement W.
- Meighan Clement W.
- Meighan Clement W.
- Porcasi F. Judith
- Raab L. Mark
- Rogers David
- Rosenthal Jeffrey S.
- Sawyer William A.
- Sutton Mark Q.
- Sutton Mark Q.
- True Delbert L.
- Vellanoweth René L.
- Wallace William J.
- Wallace William J.
- Publication venue
- 'Maney Publishing'
- Publication date
- Field of study
A polygenic resilience score moderates the genetic risk for schizophrenia.
- Author
- Adolfsson Rolf
- Agartz Ingrid
- Agerbo Esben
- Albus Margot
- Alexander Madeline
- Als Thomas D
- Amin Farooq
- Andreassen Ole A
- Arranz Maria J
- Bacanu Silviu A
- Bakker Steven
- Band Gavin
- Barroso Ines
- Begemann Martin
- Bellenguez Céline
- Belliveau Richard A
- Bender Stephan
- Bene Judit
- Bergen Sarah E
- Bevilacqua Elizabeth
- Bigdeli Tim B
- Black Donald W
- Blackburn Hannah
- Blackwell Jenefer M
- Blackwood Douglas H R
- Bramon Elvira
- Brown Matthew A
- Bruggeman Richard
- Buccola Nancy G
- Buckner Randy L
- Bulik-Sullivan Brendan
- Bumpstead Suzannah J
- Buxbaum Joseph D
- Byberg-Grauholm Jonas
- Byerley William
- Bækvad-Hansen Marie
- Børglum Anders D
- Cahn Wiepke
- Cai Guiqing
- Cairns Murray J
- Campion Dominique
- Cantor Rita M
- Carr Vaughan J
- Carrera Noa
- Casas Juan P
- Catts Stanley V
- Chambert Kimberley D
- Chan Raymond C K
- Chan Ronald Y L
- Chen Eric Y H
- Cheng Wei
- Cheung Eric F C
- Chong Siow Ann
- Cichon Sven
- Clair David St
- Cloninger C Robert
- Cohen David
- Cohen Nadine
- Collier David A
- Consortium Schizophrenia Working Group of the Psychiatric Genomics
- Cormican Paul
- Corvin Aiden
- Craddock Nick
- Crespo-Facorro Benedicto
- Crowley James J
- Curtis David
- Daly Mark J
- Darvasi Ariel
- Davidson Michael
- Davis Kenneth L
- de Haan Lieuwe
- Degenhardt Franziska
- Del Favero Jurgen
- DeLisi Lynn E
- Deloukas Panos
- Demontis Ditte
- Dikeos Dimitris
- Dinan Timothy
- Djurovic Srdjan
- Domenici Enrico
- Donnelly Peter
- Donohoe Gary
- Drapeau Elodie
- Dronov Serge
- Duan Jubao
- Dudbridge Frank
- Duncanson Audrey
- Durmishi Naser
- Edenberg Howard J
- Edkins Sarah
- Ehrenreich Hannelore
- Eichhammer Peter
- Eriksson Johan
- Escott-Price Valentina
- Esko Tõnu
- Essioux Laurent
- Fanous Ayman H
- Faraone Stephen V
- Farh Kai-How
- Farrell Martilias S
- Frank Josef
- Franke Lude
- Freedman Robert
- Freeman Colin
- Freimer Nelson B
- Friedl Marion
- Friedman Joseph I
- Fromer Menachem
- Gejman Pablo V
- Genovese Giulio
- Georgieva Lyudmila
- Gershon Elliot S
- Giannoulatou Eleni
- Giegling Ina
- Gill Michael
- Gillman Matthew
- Giusti-Rodríguez Paola
- Glatt Stephen J
- Godard Stephanie
- Goldstein Jacqueline I
- Golimbet Vera
- Gopal Srihari
- Gratten Jacob
- Gray Emma
- Greenwood Tiffany A
- Grove Jakob
- Gurling Hugh
- Gwilliam Rhian
- Hall Jeremy
- Hammer Christian
- Hammond Naomi
- Hamshere Marian L
- Hansen Mark
- Hansen Thomas
- Haroutunian Vahram
- Hartmann Annette M
- Hellenthal Garrett
- Henskens Frans A
- Herms Stefan
- Hess Jonathan L
- Hirschhorn Joel N
- Hoffmann Per
- Hofman Andrea
- Hollegaard Mads V
- Holmans Peter
- Hougaard David M
- Huang Hailiang
- Hultman Christina M
- Hunt Sarah E
- Ikeda Masashi
- Iwata Nakao
- Iyegbe Conrad
- Jablensky Assen V
- Jankowski Janusz
- Jayakumar Alagurevathi
- Joa Inge
- Julià Antonio
- Jönsson Erik G
- Kahn René S
- Kalaydjieva Luba
- Karachanak-Yankova Sena
- Karjalainen Juha
- Kavanagh David
- Keller Matthew C
- Kelly Brian J
- Kendler Kenneth S
- Kennedy James L
- Khrunin Andrey
- Kim Yunjung
- Kirov George
- Klovins Janis
- Knight Jo
- Knowles James A
- Konte Bettina
- Kucinskas Vaidutis
- Kucinskiene Zita Ausrele
- Kuzelova-Ptackova Hana
- Kähler Anna K
- Lam Max
- Langford Cordelia
- Laurent Claudine
- Lawrie Stephen
- Lee Jimmy
- Lee Phil
- Lee S Hong
- Legge Sophie E
- Lencz Todd
- Lerer Bernard
- Levinson Douglas F
- Lewis Cathryn M
- Li Miaoxin
- Li Qingqin S
- Li Tao
- Liang Kung-Yee
- Liddle Jennifer
- Lieberman Jeffrey
- Limborska Svetlana
- Lin Kuang
- Linszen Don H
- Liu Jianjun
- Loughland Carmel M
- Lubinski Jan
- Lönnqvist Jouko
- Macek Milan
- Magnusson Patrik K E
- Maher Brion S
- Maier Wolfgang
- Malhotra Anil K
- Mallet Jacques
- Markus Hugh S
- Marsal Sara
- Mata Ignacio
- Mathew Christopher G
- Mattheisen Manuel
- Mattingsdal Morten
- McCann Owen T
- McCarley Robert W
- McCarroll Steven A
- McCarthy Mark I
- McDonald Colm
- McIntosh Andrew M
- McQuillin Andrew
- Meier Sandra
- Meijer Carin J
- Melegh Bela
- Melle Ingrid
- Mesholam-Gately Raquelle I
- Metspalu Andres
- Michie Patricia T
- Milani Lili
- Milanova Vihra
- Mokrab Younes
- Moran Jennifer L
- Morris Derek W
- Mors Ole
- Mortensen Preben Bo
- Mowry Bryan J
- Murphy Kieran C
- Murray Robin M
- Myin-Germeys Inez
- Müller-Myhsok Bertram
- Neale Benjamin M
- Nelis Mari
- Nenadic Igor
- Nertney Deborah A
- Nestadt Gerald
- Nicodemus Kristin K
- Nikitina-Zake Liene
- Nisenbaum Laura
- Nordentoft Merete
- Nordin Annelie
- Norgren Nina
- Nöthen Markus M
- O'Callaghan Eadbhard
- O'Donovan Michael C
- O'Dushlaine Colm
- O'Neill F Anthony
- Oh Sang-Yun
- Olincy Ann
- Olsen Line
- Ophoff Roel A
- Owen Michael J
- Paciga Sara A
- Palmer Colin N A
- Palotie Aarno
- Pantelis Christos
- Papadimitriou George N
- Papiol Sergi
- Parkhomenko Elena
- Pato Carlos N
- Pato Michele T
- Paunio Tiina
- Pearson Richard
- Pejovic-Milovancevic Milica
- Perkins Diana O
- Pers Tune H
- Petryshen Tracey L
- Pietiläinen Olli
- Pimm Jonathan
- Pirinen Matti
- Plomin Robert
- Pocklington Andrew J
- Posthuma Danielle
- Potter Simon C
- Powell John
- Price Alkes
- Pulver Ann E
- Purcell Shaun M
- Quested Digby
- Rasmussen Henrik B
- Rautanen Anna
- Ravindrarajah Radhi
- Reichenberg Abraham
- Reimers Mark A
- Research Lundbeck Foundation Initiative for Integrative Psychiatric
- Richards Alexander L
- Ricketts Michelle
- Rietschel Marcella
- Riley Brien P
- Ripke Stephan
- Roffman Joshua L
- Roussos Panos
- Ruderfer Douglas M
- Rujescu Dan
- Salomaa Veikko
- Sanders Alan R
- Sawcer Stephen J
- Schall Ulrich
- Schubert Christian R
- Schulze Thomas G
- Schwab Sibylle G
- Scolnick Edward M
- Scott Rodney J
- Seidman Larry J
- Sham Pak C
- Shi Jianxin
- Sigurdsson Engilbert
- Sigurdsson Engilbert
- Silagadze Teimuraz
- Silverman Jeremy M
- Sim Kang
- Sklar Pamela
- Slominsky Petr
- Smoller Jordan W
- So Hon-Cheong
- Spencer Chris C A
- Stahl Eli A
- Stefánsson Hreinn
- Stefánsson Kári
- Steinberg Stacy
- Stogmann Elisabeth
- Strange Amy
- Straub Richard E
- Strengman Eric
- Strohmaier Jana
- Stroup T Scott
- Su Zhan
- Subramaniam Mythily
- Sullivan Patrick F
- Suvisaari Jaana
- Svrakic Dragan M
- Szatkiewicz Jin P
- Söderman Erik
- Tashakkori-Ghanbaria Avazeh
- Thirumalai Srinivas
- Toncheva Draga
- Tooney Paul A
- Tosato Sarah
- Trembath Richard C
- Tsuang Ming T
- Tylee Daniel S
- Van Os Jim
- Veijola Juha
- Visscher Peter M
- Viswanathan Ananth C
- Vukcevic Damjan
- Waddington John
- Waller Matthew
- Walsh Dermot
- Walshe Muriel
- Walters James T R
- Wang Dai
- Wang Qiang
- Webb Bradley T
- Weinberger Daniel R
- Weisbrod Matthias
- Weiser Mark
- Wendland Jens R
- Werge Thomas
- Weston Paul
- Whittaker Pamela
- Widaa Sara
- Wiersma Durk
- Wildenauer Dieter B
- Williams Nigel M
- Williams Stephanie
- Witt Stephanie H
- Wolen Aaron R
- Wong Emily H M
- Wood Nicholas W
- Wormley Brandon K
- Wray Naomi R
- Wu Jing Qin
- Xi Hualin Simon
- Zai Clement C
- Zheng Xuebin
- Zimprich Fritz
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2019
- Field of study
Based on the discovery by the Resilience Project (Chen R. et al. Nat Biotechnol 34:531-538, 2016) of rare variants that confer resistance to Mendelian disease, and protective alleles for some complex diseases, we posited the existence of genetic variants that promote resilience to highly heritable polygenic disorders1,0 such as schizophrenia. Resilience has been traditionally viewed as a psychological construct, although our use of the term resilience refers to a different construct that directly relates to the Resilience Project, namely: heritable variation that promotes resistance to disease by reducing the penetrance of risk loci, wherein resilience and risk loci operate orthogonal to one another. In this study, we established a procedure to identify unaffected individuals with relatively high polygenic risk for schizophrenia, and contrasted them with risk-matched schizophrenia cases to generate the first known "polygenic resilience score" that represents the additive contributions to SZ resistance by variants that are distinct from risk loci. The resilience score was derived from data compiled by the Psychiatric Genomics Consortium, and replicated in three independent samples. This work establishes a generalizable framework for finding resilience variants for any complex, heritable disorder