Understanding Early Intervention Services for Hispanic Children with Autism Spectrum Disorders

Clear communication between speech-language pathologists and their clients and client’s families is essential for the success of therapy. A common language between therapist and client also facilitates the exchange of information, however this is not always possible. The purpose of this study was to develop a Fotonovela as an informative tool for Hispanic parents with children in the autism spectrum to use as an early intervention guide, to provide information on therapy services and to promote the understanding between professionals and culturally diverse populations. A Fotonovela is a pamphlet with photographs in the comic-book format that usually depicts a story with a soap-opera type plot with short dialogue bubbles. The Fotonovela created was adapted to serve as an informative tool for families and speech-language pathologists working with culturally and linguistically diverse populations. The booklet focused mainly on a basic depiction of the diagnostic process beginning with commonly known symptoms of autism, then it depicted three commonly used early intervention therapy techniques for ASD that were found useful from evidence based practice research. The therapy techniques were described in a simple manner in order to reach low literacy Latino audiences. A second product was also created as a companion piece of an online document offered by the Autism Speaks website. The purpose of this piece was to simplify a lengthy document into a simple and user-friendly introductory booklet for the benefit of low literacy Latino families as well. It was originally created in Spanish and then translated into English for the benefit non-Spanish speaking families and professionals

Estudios de los materiales cerámicos históricos procedentes del Área Fundacional de la Ciudad de Mendoza

En este trabajo, editado en la revista NAyA ( noticias de Antropología y Arqueología) se describen los contextos alfareros de períodos históricos procedentes de la ciudad de Mendoza

Excavación arqueológica y análisis bioarqueológico en el cementerio de la capital (Mendoza): Repatriación de los restos de Santos Ortiz e Inés Vélez de Ortiz

En este trabajo se dan a conocer los resultados de las excavaciones arqueológicas realizadas en dos sepulturas del Cementerio de la Ciudad de Mendoza y de los análisis bioarqueológicos efectuados sobre los restos óseos de los cinco individuos exhumados. Estos estudios se realizaron en el marco del pedido de repatriación de los restos de Don José Santos Ortiz y Doña Inés Vélez de Ortiz, por parte del gobierno de la provincia de San Luis y los familiares. La exhumación y el estudio de los restos óseos fue autorizada por la dirección general de patrimonio de Mendoza. Se presenta la metodología empleada para la identificación de los individuos, así como también, las técnicas empleadas para el re-ensamblaje anatómico de los conjuntos desarticulados. Las altas frecuencias de pérdidas dentales registradas se asocian probablemente con una dieta rica en carbohidratos y con las edades avanzadas de los individuos. Por otro lado, la combinación de la evidencia bioarqueológica con la información de diferentes fuentes documentales permitieron realizar interpretaciones más ajustadas sobre las relaciones familiares de los individuos así como también sobre la causa de muerte de uno de los individuos que presentaba señales de violencia.Este artigo revela os resultados de escavações arqueológicas em duas sepulturas no cemitério da cidade de Mendoza e análise bioarchaeological realizadas em restos de esqueletos de cinco indivíduos exumados. Estes estudos foram conduzidos sob o pedido de repatriação dos restos mortais de Dom José Santos Ortiz e Inês Velez de Ortiz, pelo governo da província de San Luis e familiares. A exumação e estudo de restos de esqueletos foi autorizado pela direção geral do património de Mendoza. Ele apresenta a metodologia para a identificação de indivíduos, bem como as técnicas utilizadas para anatômica sets remontagem desarticulada. A alta freqüência de perda dentária registrados provavelmente está associado com uma dieta rica em carboidratos e com idosos. Por outro lado, a combinação de provas com fontes de informação bioarchaeological documentário permitiu a interpretações diferentes, ajustados nas relações familiares dos indivíduos, bem como a causa da morte de indivíduos que apresentavam sinais de violência.This paper discloses the results of archaeological excavations in two graves in the cemetery of the city of Mendoza and bioarchaeological analysis carried out on skeletal remains of five individuals exhumed. These studies were conducted under the request for repatriation of the remains of Don Jose Santos Ortiz and Doña Ines Velez de Ortiz, by the government of the province of San Luis and family members. The exhumation and study of skeletal remains was authorized by the general direction of the heritage of Mendoza. It presents the methodology for the identification of individuals, as well as the techniques used for anatomical reassembly disjointed sets. The high frequency of tooth loss recorded is probably associated with a diet rich in carbohydrates and with elderly individuals. On the other hand, the combination of evidence with information bioarchaeological documentary sources allowed for different interpretations adjusted on family relationships of individuals as well as the cause of death of individuals who showed signs of violence.Fil: Mansegosa, Daniela Alit. Universidad Nacional de la Plata. Facultad de Ciencias Naturales y Museo; ArgentinaFil: Zorrilla, Valeria. Universidad Nacional de Cuyo. Facultad de Filosofia y Letras; ArgentinaFil: Prieto Olavarría, Cristina Alejandra. Consejo Nacional de Investigaciones Científicas y Técnicas. Científico Tecnológico Mendoza. Instituto Argentino de Nivologia, Glaciologia y Ciencias Ambientales; Argentina. Universidad Nacional de Cuyo. Facultad de Filosofia y Letras; ArgentinaFil: Giannotti, Pablo Sebastián. Universidad Nacional de Cuyo. Facultad de Filosofia y Letras; Argentin

Cultura material y sociedad en el siglo XIX: las lozas en la ciudad de Mendoza

Considerando a la ciudad de Mendoza como sitio, se analizaron las lozas procedentes de 16 excavaciones correspondientes a contextos previos y posteriores al terremoto de 1861. Las distribuciones de lozas en el espacio por categorías o clases discriminadas según su valoración y la comparación con las tendencias de las cerámicas de producción local permiten indagar las diferencias de consumo dentro de la sociedad mendocina a lo largo del siglo XIX

The hypothalamic endocannabinoid system participates in the secretion of oxytocin and tumor necrosis factor-alpha induced by lipopolysaccharide

This study investigated the participation of the hypothalamic endocannabinoid system in the response to lipopolysaccharide (LPS) challenge evaluating oxytocin (OXT) and tumor necrosis factor-alpha (TNF-a) plasma levels in vivo and their release from hypothalamic fragments in vitro. LPS increased OXT and TNF-α release through anandamide-activation of hypothalamic cannabinoid receptor CB1, since the antagonist AM251 blocked this effect. Anandamide, through its receptors, also increased hypothalamic nitric oxide (NO) which inhibited OXT release, ending the stimulatory effect of the endocannabinoid. Our findings reveal a hypothalamic interaction between oxytocin, endocannabinoid and NO-ergic systems providing a regulation of the hypothalamic-neurohypophyseal axis under basal and stress conditions.Fil: de Laurentiis, Andrea. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Centro de Estudios Farmacológicos y Botánicos. Universidad de Buenos Aires. Facultad de Medicina. Centro de Estudios Farmacológicos y Botánicos; ArgentinaFil: Fernández Solari, José Javier. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Centro de Estudios Farmacológicos y Botánicos. Universidad de Buenos Aires. Facultad de Medicina. Centro de Estudios Farmacológicos y Botánicos; ArgentinaFil: Mohn, Claudia Ester. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Centro de Estudios Farmacológicos y Botánicos. Universidad de Buenos Aires. Facultad de Medicina. Centro de Estudios Farmacológicos y Botánicos; ArgentinaFil: Burdet, Berenice. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Centro de Estudios Farmacológicos y Botánicos. Universidad de Buenos Aires. Facultad de Medicina. Centro de Estudios Farmacológicos y Botánicos; ArgentinaFil: Zorrilla Zubilete, María Aurelia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Centro de Estudios Farmacológicos y Botánicos. Universidad de Buenos Aires. Facultad de Medicina. Centro de Estudios Farmacológicos y Botánicos; ArgentinaFil: Rettori, Valeria. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Centro de Estudios Farmacológicos y Botánicos. Universidad de Buenos Aires. Facultad de Medicina. Centro de Estudios Farmacológicos y Botánicos; Argentin

Excavación arqueológica y análisis bioarqueológico en el cementerio de la capital (Mendoza) : Repatriación de los restos de Santos Ortiz e Inés Vélez de Ortiz

En este trabajo se dan a conocer los resultados de las excavaciones arqueológicas realizadas en dos sepulturas del Cementerio de la Ciudad de Mendoza y de los análisis bioarqueológicos efectuados sobre los restos óseos de los cinco individuos exhumados. Estos estudios se realizaron en el marco del pedido de repatriación de los restos de Don José Santos Ortiz y Doña Inés Vélez de Ortiz, por parte del gobierno de la provincia de San Luis y los familiares. La exhumación y el estudio de los restos óseos fue autorizada por la dirección general de patrimonio de Mendoza. Se presenta la metodología empleada para la identificación de los individuos, así como también, las técnicas empleadas para el re-ensamblaje anatómico de los conjuntos desarticulados. Las altas frecuencias de pérdidas dentales registradas se asocian probablemente con una dieta rica en carbohidratos y con las edades avanzadas de los individuos. Por otro lado, la combinación de la evidencia bioarqueológica con la información de diferentes fuentes documentales permitieron realizar interpretaciones más ajustadas sobre las relaciones familiares de los individuos así como también sobre la causa de muerte de uno de los individuos que presentaba señales de violencia.Este artigo revela os resultados de escavações arqueológicas em duas sepulturas no cemitério da cidade de Mendoza e análise bioarchaeological realizadas em restos de esqueletos de cinco indivíduos exumados. Estes estudos foram conduzidos sob o pedido de repatriação dos restos mortais de Dom José Santos Ortiz e Inês Velez de Ortiz, pelo governo da província de San Luis e familiares. A exumação e estudo de restos de esqueletos foi autorizado pela direção geral do património de Mendoza. Ele apresenta a metodologia para a identificação de indivíduos, bem como as técnicas utilizadas para anatômica sets remontagem desarticulada. A alta freqüência de perda dentária registrados provavelmente está associado com uma dieta rica em carboidratos e com idosos. Por outro lado, a combinação de provas com fontes de informação bioarchaeological documentário permitiu a interpretações diferentes, ajustados nas relações familiares dos indivíduos, bem como a causa da morte de indivíduos que apresentavam sinais de violência.This paper discloses the results of archaeological excavations in two graves in the cemetery of the city of Mendoza and bioarchaeological analysis carried out on skeletal remains of five individuals exhumed. These studies were conducted under the request for repatriation of the remains of Don Jose Santos Ortiz and Doña Ines Velez de Ortiz, by the government of the province of San Luis and family members. The exhumation and study of skeletal remains was authorized by the general direction of the heritage of Mendoza. It presents the methodology for the identification of individuals, as well as the techniques used for anatomical reassembly disjointed sets. The high frequency of tooth loss recorded is probably associated with a diet rich in carbohydrates and with elderly individuals. On the other hand, the combination of evidence with information bioarchaeological documentary sources allowed for different interpretations adjusted on family relationships of individuals as well as the cause of death of individuals who showed signs of violence.Facultad de Ciencias Naturales y Muse

Excavación arqueológica y análisis bioarqueológico en el cementerio de la capital (Mendoza) : Repatriación de los restos de Santos Ortiz e Inés Vélez de Ortiz

En este trabajo se dan a conocer los resultados de las excavaciones arqueológicas realizadas en dos sepulturas del Cementerio de la Ciudad de Mendoza y de los análisis bioarqueológicos efectuados sobre los restos óseos de los cinco individuos exhumados. Estos estudios se realizaron en el marco del pedido de repatriación de los restos de Don José Santos Ortiz y Doña Inés Vélez de Ortiz, por parte del gobierno de la provincia de San Luis y los familiares. La exhumación y el estudio de los restos óseos fue autorizada por la dirección general de patrimonio de Mendoza. Se presenta la metodología empleada para la identificación de los individuos, así como también, las técnicas empleadas para el re-ensamblaje anatómico de los conjuntos desarticulados. Las altas frecuencias de pérdidas dentales registradas se asocian probablemente con una dieta rica en carbohidratos y con las edades avanzadas de los individuos. Por otro lado, la combinación de la evidencia bioarqueológica con la información de diferentes fuentes documentales permitieron realizar interpretaciones más ajustadas sobre las relaciones familiares de los individuos así como también sobre la causa de muerte de uno de los individuos que presentaba señales de violencia.Este artigo revela os resultados de escavações arqueológicas em duas sepulturas no cemitério da cidade de Mendoza e análise bioarchaeological realizadas em restos de esqueletos de cinco indivíduos exumados. Estes estudos foram conduzidos sob o pedido de repatriação dos restos mortais de Dom José Santos Ortiz e Inês Velez de Ortiz, pelo governo da província de San Luis e familiares. A exumação e estudo de restos de esqueletos foi autorizado pela direção geral do património de Mendoza. Ele apresenta a metodologia para a identificação de indivíduos, bem como as técnicas utilizadas para anatômica sets remontagem desarticulada. A alta freqüência de perda dentária registrados provavelmente está associado com uma dieta rica em carboidratos e com idosos. Por outro lado, a combinação de provas com fontes de informação bioarchaeological documentário permitiu a interpretações diferentes, ajustados nas relações familiares dos indivíduos, bem como a causa da morte de indivíduos que apresentavam sinais de violência.This paper discloses the results of archaeological excavations in two graves in the cemetery of the city of Mendoza and bioarchaeological analysis carried out on skeletal remains of five individuals exhumed. These studies were conducted under the request for repatriation of the remains of Don Jose Santos Ortiz and Doña Ines Velez de Ortiz, by the government of the province of San Luis and family members. The exhumation and study of skeletal remains was authorized by the general direction of the heritage of Mendoza. It presents the methodology for the identification of individuals, as well as the techniques used for anatomical reassembly disjointed sets. The high frequency of tooth loss recorded is probably associated with a diet rich in carbohydrates and with elderly individuals. On the other hand, the combination of evidence with information bioarchaeological documentary sources allowed for different interpretations adjusted on family relationships of individuals as well as the cause of death of individuals who showed signs of violence.Facultad de Ciencias Naturales y Muse

FINAHORRO

Según la Superintendencia de Banca y Seguros, el ahorro ha aumentado durante la llegada del coronavirus a Perú. Se ha podido identificar el crecimiento de este mercado del ahorro ya que, no solo han cambiado nuestras costumbres de consumo. Durante el confinamiento, se ha observado un mayor interés de las personas hacia las alternativas de ahorro que ofrece el mercado financiero. Como resultado de nuestra investigación y recolección de información, se ha determinado una oportunidad de negocio que ayudará a encontrar una solución al problema identificado. Nuestra idea corresponde a una aplicación que ayuda al consumidor peruana ha ahorrar, en esta app podrá distribuir sus gastos como mejor se le acomode, en cualquier momento y en cualquier lugar. Finahorro tendrá un concepto más colorido y amical ya que va dirigido solo para personas de 18 a 25 años. Las descargas serán por App Store y Play Store. Al entrar a la app, el usuario deberá rellenar sus datos personales y le haremos una serie de preguntas con respecto a cuáles son sus propósitos financieros y objetivos como: “viajes, ropa, estudios, un auto, entre otros”. Al tener la información del cliente y conocer su visión y expectativas, diseñaremos incentivos para que esta persona vaya logrando sus objetivos de manera más consciente.According to Superintendencia de Banca y Seguros, savings have increased during the arrival of the coronavirus in Peru. It has been possible to identify the growth of this savings market, because not only have their consumption habits changed. During the confinement, a greater interest of people towards the savings alternatives offered by the financial market has been observed. As a result of our investigation and information gathering, a business opportunity has been determined that we will help find a solution to the identified problem. Our idea is f to an app that helps the Peruvian consumer to save. In this app you can distribute your expenses as you wish, at any time and in any place. Finahorro will have a more colorful and friendly concept, because it is aimed at people between 18 and 25 years old. Downloads will be by App Store and Play Store. When entering the application, the user must complete their personal data and we will ask a series of questions about their financial goals and objectives, such as travel, clothing, studies, a car, etc. With the client's information, their goals and expectations, we will design challenges so that this person can constantly achieve their objectives.Trabajo de investigació

Antimicrobial resistance among migrants in Europe: a systematic review and meta-analysis

BACKGROUND: Rates of antimicrobial resistance (AMR) are rising globally and there is concern that increased migration is contributing to the burden of antibiotic resistance in Europe. However, the effect of migration on the burden of AMR in Europe has not yet been comprehensively examined. Therefore, we did a systematic review and meta-analysis to identify and synthesise data for AMR carriage or infection in migrants to Europe to examine differences in patterns of AMR across migrant groups and in different settings. METHODS: For this systematic review and meta-analysis, we searched MEDLINE, Embase, PubMed, and Scopus with no language restrictions from Jan 1, 2000, to Jan 18, 2017, for primary data from observational studies reporting antibacterial resistance in common bacterial pathogens among migrants to 21 European Union-15 and European Economic Area countries. To be eligible for inclusion, studies had to report data on carriage or infection with laboratory-confirmed antibiotic-resistant organisms in migrant populations. We extracted data from eligible studies and assessed quality using piloted, standardised forms. We did not examine drug resistance in tuberculosis and excluded articles solely reporting on this parameter. We also excluded articles in which migrant status was determined by ethnicity, country of birth of participants' parents, or was not defined, and articles in which data were not disaggregated by migrant status. Outcomes were carriage of or infection with antibiotic-resistant organisms. We used random-effects models to calculate the pooled prevalence of each outcome. The study protocol is registered with PROSPERO, number CRD42016043681. FINDINGS: We identified 2274 articles, of which 23 observational studies reporting on antibiotic resistance in 2319 migrants were included. The pooled prevalence of any AMR carriage or AMR infection in migrants was 25·4% (95% CI 19·1-31·8; I2 =98%), including meticillin-resistant Staphylococcus aureus (7·8%, 4·8-10·7; I2 =92%) and antibiotic-resistant Gram-negative bacteria (27·2%, 17·6-36·8; I2 =94%). The pooled prevalence of any AMR carriage or infection was higher in refugees and asylum seekers (33·0%, 18·3-47·6; I2 =98%) than in other migrant groups (6·6%, 1·8-11·3; I2 =92%). The pooled prevalence of antibiotic-resistant organisms was slightly higher in high-migrant community settings (33·1%, 11·1-55·1; I2 =96%) than in migrants in hospitals (24·3%, 16·1-32·6; I2 =98%). We did not find evidence of high rates of transmission of AMR from migrant to host populations. INTERPRETATION: Migrants are exposed to conditions favouring the emergence of drug resistance during transit and in host countries in Europe. Increased antibiotic resistance among refugees and asylum seekers and in high-migrant community settings (such as refugee camps and detention facilities) highlights the need for improved living conditions, access to health care, and initiatives to facilitate detection of and appropriate high-quality treatment for antibiotic-resistant infections during transit and in host countries. Protocols for the prevention and control of infection and for antibiotic surveillance need to be integrated in all aspects of health care, which should be accessible for all migrant groups, and should target determinants of AMR before, during, and after migration. FUNDING: UK National Institute for Health Research Imperial Biomedical Research Centre, Imperial College Healthcare Charity, the Wellcome Trust, and UK National Institute for Health Research Health Protection Research Unit in Healthcare-associated Infections and Antimictobial Resistance at Imperial College London

Surgical site infection after gastrointestinal surgery in high-income, middle-income, and low-income countries: a prospective, international, multicentre cohort study

Background: Surgical site infection (SSI) is one of the most common infections associated with health care, but its importance as a global health priority is not fully understood. We quantified the burden of SSI after gastrointestinal surgery in countries in all parts of the world. Methods: This international, prospective, multicentre cohort study included consecutive patients undergoing elective or emergency gastrointestinal resection within 2-week time periods at any health-care facility in any country. Countries with participating centres were stratified into high-income, middle-income, and low-income groups according to the UN's Human Development Index (HDI). Data variables from the GlobalSurg 1 study and other studies that have been found to affect the likelihood of SSI were entered into risk adjustment models. The primary outcome measure was the 30-day SSI incidence (defined by US Centers for Disease Control and Prevention criteria for superficial and deep incisional SSI). Relationships with explanatory variables were examined using Bayesian multilevel logistic regression models. This trial is registered with ClinicalTrials.gov, number NCT02662231. Findings: Between Jan 4, 2016, and July 31, 2016, 13 265 records were submitted for analysis. 12 539 patients from 343 hospitals in 66 countries were included. 7339 (58·5%) patient were from high-HDI countries (193 hospitals in 30 countries), 3918 (31·2%) patients were from middle-HDI countries (82 hospitals in 18 countries), and 1282 (10·2%) patients were from low-HDI countries (68 hospitals in 18 countries). In total, 1538 (12·3%) patients had SSI within 30 days of surgery. The incidence of SSI varied between countries with high (691 [9·4%] of 7339 patients), middle (549 [14·0%] of 3918 patients), and low (298 [23·2%] of 1282) HDI (p < 0·001). The highest SSI incidence in each HDI group was after dirty surgery (102 [17·8%] of 574 patients in high-HDI countries; 74 [31·4%] of 236 patients in middle-HDI countries; 72 [39·8%] of 181 patients in low-HDI countries). Following risk factor adjustment, patients in low-HDI countries were at greatest risk of SSI (adjusted odds ratio 1·60, 95% credible interval 1·05–2·37; p=0·030). 132 (21·6%) of 610 patients with an SSI and a microbiology culture result had an infection that was resistant to the prophylactic antibiotic used. Resistant infections were detected in 49 (16·6%) of 295 patients in high-HDI countries, in 37 (19·8%) of 187 patients in middle-HDI countries, and in 46 (35·9%) of 128 patients in low-HDI countries (p < 0·001). Interpretation: Countries with a low HDI carry a disproportionately greater burden of SSI than countries with a middle or high HDI and might have higher rates of antibiotic resistance. In view of WHO recommendations on SSI prevention that highlight the absence of high-quality interventional research, urgent, pragmatic, randomised trials based in LMICs are needed to assess measures aiming to reduce this preventable complication