Discovery of biological networks from diverse functional genomic data

We have developed a general probabilistic system for query-based discovery of pathway-specific networks through integration of diverse genome-wide data. This framework was validated by accurately recovering known networks for 31 biological processes in Saccharomyces cerevisiae and experimentally verifying predictions for the process of chromosomal segregation. Our system, bioPIXIE, a public, comprehensive system for integration, analysis, and visualization of biological network predictions for S. cerevisiae, is freely accessible over the worldwide web

2005 Myers et Volume al. 6, Issue 13, Article R114 Open Access Method Discovery of biological networks from diverse functional genomic

dat

Patterns of morphological variation of extant sloth skulls and their implication for future conservation efforts

International audienc