STUDY OF EARLY AND LATE ONSET COMPLICATIONS OF TRANSSPHENOIDAL PITUITARY ADENOMA RESECTION: AN INSTITUITIONAL EXPERIENCE.

Introduction:Considering the unique anatomical location and important role of pituitary gland in regulation of various endocrine functions, various postoperative complications are expected resulting from surgery on pituitary tumor. In this study, we analyzed various complications of transsphenoidal pituitary surgery and factors affecting it. Material and method:Study was conducted between September 2015 to November 2016 on a total of 60 patients. All clinical and surgical data were collected regarding tumor size, symptoms, and residual tumor after surgery, functional remission, symptom relief, and complications. All patients underwent neurological, ophthalmological, and endocrinological examinations before and after resection. Result:Out of 60 patients 43 were operated endoscopically and 17 were operated microscopically. Perioperatively, arachnoid tear was present in 20(33.33%) patients. 23(38.34%) cases were having total resection post-operatively, 20(33.33%) cases were having subtotal resection and in 17 (28.33%) cases either partial resection done or biopsy was taken. Grade of tumor resection was significantly associated with preoperative extent of tumor (p-value-0.003). CSF -leak was associated with Perioperative arachnoid tear significantly (p- value <0.001). Conclusion:Some complications are there in immediate post operative period, but on follow up, both endoscopic and microscopic procedures have fewer side effects and there was no statistical significant difference in complication rate in both types of surgery

Once in a blue moon: detection of ‘bluing’ during debris transits in the white dwarf WD 1145+017

The first transiting planetesimal orbiting a white dwarf was recently detected in K2 data of WD 1145+017 and has been followed up intensively. The multiple, long and variable transits suggest the transiting objects are dust clouds, probably produced by a disintegrating asteroid. In addition, the system contains circumstellar gas, evident by broad absorption lines, mostly in the u΄ band, and a dust disc, indicated by an infrared excess. Here we present the first detection of a change in colour of WD 1145+017 during transits, using simultaneous multiband fast-photometry ULTRACAM measurements over the u΄g΄r΄i΄ bands. The observations reveal what appears to be ‘bluing' during transits; transits are deeper in the redder bands, with a u΄ − r΄ colour difference of up to ∼−0.05 mag. We explore various possible explanations for the bluing, including limb darkening or peculiar dust properties. ‘Spectral' photometry obtained by integrating over bandpasses in the spectroscopic data in and out of transit, compared to the photometric data, shows that the observed colour difference is most likely the result of reduced circumstellar absorption in the spectrum during transits. This indicates that the transiting objects and the gas share the same line of sight and that the gas covers the white dwarf only partially, as would be expected if the gas, the transiting debris and the dust emitting the infrared excess are part of the same general disc structure (although possibly at different radii). In addition, we present the results of a week-long monitoring campaign of the system using a global network of telescopes

Search for a W' boson decaying to a bottom quark and a top quark in pp collisions at sqrt(s) = 7 TeV

Results are presented from a search for a W' boson using a dataset corresponding to 5.0 inverse femtobarns of integrated luminosity collected during 2011 by the CMS experiment at the LHC in pp collisions at sqrt(s)=7 TeV. The W' boson is modeled as a heavy W boson, but different scenarios for the couplings to fermions are considered, involving both left-handed and right-handed chiral projections of the fermions, as well as an arbitrary mixture of the two. The search is performed in the decay channel W' to t b, leading to a final state signature with a single lepton (e, mu), missing transverse energy, and jets, at least one of which is tagged as a b-jet. A W' boson that couples to fermions with the same coupling constant as the W, but to the right-handed rather than left-handed chiral projections, is excluded for masses below 1.85 TeV at the 95% confidence level. For the first time using LHC data, constraints on the W' gauge coupling for a set of left- and right-handed coupling combinations have been placed. These results represent a significant improvement over previously published limits.Comment: Submitted to Physics Letters B. Replaced with version publishe

Search for the standard model Higgs boson decaying into two photons in pp collisions at sqrt(s)=7 TeV

A search for a Higgs boson decaying into two photons is described. The analysis is performed using a dataset recorded by the CMS experiment at the LHC from pp collisions at a centre-of-mass energy of 7 TeV, which corresponds to an integrated luminosity of 4.8 inverse femtobarns. Limits are set on the cross section of the standard model Higgs boson decaying to two photons. The expected exclusion limit at 95% confidence level is between 1.4 and 2.4 times the standard model cross section in the mass range between 110 and 150 GeV. The analysis of the data excludes, at 95% confidence level, the standard model Higgs boson decaying into two photons in the mass range 128 to 132 GeV. The largest excess of events above the expected standard model background is observed for a Higgs boson mass hypothesis of 124 GeV with a local significance of 3.1 sigma. The global significance of observing an excess with a local significance greater than 3.1 sigma anywhere in the search range 110-150 GeV is estimated to be 1.8 sigma. More data are required to ascertain the origin of this excess.Comment: Submitted to Physics Letters

Measurement of the Lambda(b) cross section and the anti-Lambda(b) to Lambda(b) ratio with Lambda(b) to J/Psi Lambda decays in pp collisions at sqrt(s) = 7 TeV

The Lambda(b) differential production cross section and the cross section ratio anti-Lambda(b)/Lambda(b) are measured as functions of transverse momentum pt(Lambda(b)) and rapidity abs(y(Lambda(b))) in pp collisions at sqrt(s) = 7 TeV using data collected by the CMS experiment at the LHC. The measurements are based on Lambda(b) decays reconstructed in the exclusive final state J/Psi Lambda, with the subsequent decays J/Psi to an opposite-sign muon pair and Lambda to proton pion, using a data sample corresponding to an integrated luminosity of 1.9 inverse femtobarns. The product of the cross section times the branching ratio for Lambda(b) to J/Psi Lambda versus pt(Lambda(b)) falls faster than that of b mesons. The measured value of the cross section times the branching ratio for pt(Lambda(b)) > 10 GeV and abs(y(Lambda(b))) < 2.0 is 1.06 +/- 0.06 +/- 0.12 nb, and the integrated cross section ratio for anti-Lambda(b)/Lambda(b) is 1.02 +/- 0.07 +/- 0.09, where the uncertainties are statistical and systematic, respectively.Comment: Submitted to Physics Letters

Search for new physics in events with opposite-sign leptons, jets, and missing transverse energy in pp collisions at sqrt(s) = 7 TeV

A search is presented for physics beyond the standard model (BSM) in final states with a pair of opposite-sign isolated leptons accompanied by jets and missing transverse energy. The search uses LHC data recorded at a center-of-mass energy sqrt(s) = 7 TeV with the CMS detector, corresponding to an integrated luminosity of approximately 5 inverse femtobarns. Two complementary search strategies are employed. The first probes models with a specific dilepton production mechanism that leads to a characteristic kinematic edge in the dilepton mass distribution. The second strategy probes models of dilepton production with heavy, colored objects that decay to final states including invisible particles, leading to very large hadronic activity and missing transverse energy. No evidence for an event yield in excess of the standard model expectations is found. Upper limits on the BSM contributions to the signal regions are deduced from the results, which are used to exclude a region of the parameter space of the constrained minimal supersymmetric extension of the standard model. Additional information related to detector efficiencies and response is provided to allow testing specific models of BSM physics not considered in this paper.Comment: Replaced with published version. Added journal reference and DO

Measurement of isolated photon production in pp and PbPb collisions at sqrt(sNN) = 2.76 TeV

Isolated photon production is measured in proton-proton and lead-lead collisions at nucleon-nucleon centre-of-mass energies of 2.76 TeV in the pseudorapidity range |eta|<1.44 and transverse energies ET between 20 and 80 GeV with the CMS detector at the LHC. The measured ET spectra are found to be in good agreement with next-to-leading-order perturbative QCD predictions. The ratio of PbPb to pp isolated photon ET-differential yields, scaled by the number of incoherent nucleon-nucleon collisions, is consistent with unity for all PbPb reaction centralities.Comment: Submitted to Physics Letters