A pattern reconfigurable antenna using eight-dipole configuration for energy harvesting applications

A pattern reconfigurable antenna, composed of eight elements, is proposed for energy harvesting applications. Pattern reconfigurable antennas are a promising technique for harvesting from different wireless sources. The radiation pattern of the proposed antenna can be steered electronically using an RF switch matrix, covering an angle range from 0 to 360 degrees with a step size of 45 degrees. The proposed antenna primarily consists of an eight-dipole configuration that shares the same excitation. Each dipole is excited using a balun comprising a quarter-wavelength grounded stub and a quarter-wavelength open-circuit stub. The proposed antenna operates in the frequency range of 4.17 to 4.5 GHz, with an impedance bandwidth of 7.6%. By switching between the different switches, the antenna can be steered with a narrower rotational angle. In addition, the antenna can work in an omnidirectional mode when all switches are in the ON state simultaneously. The results demonstrate a good agreement between the numerical and experimental findings for the reflection coefficient and radiation characteristics of the proposed reconfigurable antenna

Characteristics and economic value of the rejected brine at Al-Khobar desalination plant in KSA

This paper presents the characteristics of seawater and rejected brine, and the economic value of the rejected brine at Al-Khobar desalination plant, KSA. The rejected brine may be discharged to sea/ocean contains of different salts and dissolved minerals in high concentrations, which carry considerable economic value in relevant industries. It is found that the rejected brine contains huge amount of SO42-, Cl-, Na+, Ca2+, Mg2+, K+, Fe2- and Cu2+, which have high economic value. Therefore, these minerals can be recovered directly from the rejected brine. This study estimated the quantities of these minerals and the revenue income according to their current market prices. Moreover, this study may help the policy/decision makers to assess the economic value of the brine to establish new industries for brine processing. Seawater and brine samples collected from the Al-Khobar plant. Various physical and chemical properties were observed in order to find economic value of minerals

Molecular generation and characterization of an efficient recombinant vaccine for avian influenza A/H5N8 in Saudi Arabia

Purpose: To characterize a highly pathogenic avian influenza (HPAI) H5N8 for engineering recombinant 6-+ 2 vaccine strain based on reverse genetic technology. Methods: A total of 135 swab samples from various birds were collected from different parts of Saudi Arabia as part of an influenza surveillance activity. The samples were checked for influenza virus infection using reverse transcriptase-polymerase chain reaction (RT-PCR). Furthermore, Avian influenza H5N8 (A/chicken/KSA/1-NRC/2018), was used for the generation of H5N8 vaccine strain. The vaccine was tested on specific pathogen-free (SPF) chicken purchased from a local market. Results: The results indicate that the candidate vaccine (rgH5N8/KSA) induced specific neutralizing antibodies in chicken, and thereby protected the chickens from subsequent infections of H5N8. Conclusion: The study reinforces the development of a vaccine against avian influenza H5N8 virus isolated in Saudi Arabia, suggesting its possible application against the influenza virus associated with bird fl

Antimicrobial resistance among migrants in Europe: a systematic review and meta-analysis

BACKGROUND: Rates of antimicrobial resistance (AMR) are rising globally and there is concern that increased migration is contributing to the burden of antibiotic resistance in Europe. However, the effect of migration on the burden of AMR in Europe has not yet been comprehensively examined. Therefore, we did a systematic review and meta-analysis to identify and synthesise data for AMR carriage or infection in migrants to Europe to examine differences in patterns of AMR across migrant groups and in different settings. METHODS: For this systematic review and meta-analysis, we searched MEDLINE, Embase, PubMed, and Scopus with no language restrictions from Jan 1, 2000, to Jan 18, 2017, for primary data from observational studies reporting antibacterial resistance in common bacterial pathogens among migrants to 21 European Union-15 and European Economic Area countries. To be eligible for inclusion, studies had to report data on carriage or infection with laboratory-confirmed antibiotic-resistant organisms in migrant populations. We extracted data from eligible studies and assessed quality using piloted, standardised forms. We did not examine drug resistance in tuberculosis and excluded articles solely reporting on this parameter. We also excluded articles in which migrant status was determined by ethnicity, country of birth of participants' parents, or was not defined, and articles in which data were not disaggregated by migrant status. Outcomes were carriage of or infection with antibiotic-resistant organisms. We used random-effects models to calculate the pooled prevalence of each outcome. The study protocol is registered with PROSPERO, number CRD42016043681. FINDINGS: We identified 2274 articles, of which 23 observational studies reporting on antibiotic resistance in 2319 migrants were included. The pooled prevalence of any AMR carriage or AMR infection in migrants was 25·4% (95% CI 19·1-31·8; I2 =98%), including meticillin-resistant Staphylococcus aureus (7·8%, 4·8-10·7; I2 =92%) and antibiotic-resistant Gram-negative bacteria (27·2%, 17·6-36·8; I2 =94%). The pooled prevalence of any AMR carriage or infection was higher in refugees and asylum seekers (33·0%, 18·3-47·6; I2 =98%) than in other migrant groups (6·6%, 1·8-11·3; I2 =92%). The pooled prevalence of antibiotic-resistant organisms was slightly higher in high-migrant community settings (33·1%, 11·1-55·1; I2 =96%) than in migrants in hospitals (24·3%, 16·1-32·6; I2 =98%). We did not find evidence of high rates of transmission of AMR from migrant to host populations. INTERPRETATION: Migrants are exposed to conditions favouring the emergence of drug resistance during transit and in host countries in Europe. Increased antibiotic resistance among refugees and asylum seekers and in high-migrant community settings (such as refugee camps and detention facilities) highlights the need for improved living conditions, access to health care, and initiatives to facilitate detection of and appropriate high-quality treatment for antibiotic-resistant infections during transit and in host countries. Protocols for the prevention and control of infection and for antibiotic surveillance need to be integrated in all aspects of health care, which should be accessible for all migrant groups, and should target determinants of AMR before, during, and after migration. FUNDING: UK National Institute for Health Research Imperial Biomedical Research Centre, Imperial College Healthcare Charity, the Wellcome Trust, and UK National Institute for Health Research Health Protection Research Unit in Healthcare-associated Infections and Antimictobial Resistance at Imperial College London

Surgical site infection after gastrointestinal surgery in high-income, middle-income, and low-income countries: a prospective, international, multicentre cohort study

Background: Surgical site infection (SSI) is one of the most common infections associated with health care, but its importance as a global health priority is not fully understood. We quantified the burden of SSI after gastrointestinal surgery in countries in all parts of the world. Methods: This international, prospective, multicentre cohort study included consecutive patients undergoing elective or emergency gastrointestinal resection within 2-week time periods at any health-care facility in any country. Countries with participating centres were stratified into high-income, middle-income, and low-income groups according to the UN's Human Development Index (HDI). Data variables from the GlobalSurg 1 study and other studies that have been found to affect the likelihood of SSI were entered into risk adjustment models. The primary outcome measure was the 30-day SSI incidence (defined by US Centers for Disease Control and Prevention criteria for superficial and deep incisional SSI). Relationships with explanatory variables were examined using Bayesian multilevel logistic regression models. This trial is registered with ClinicalTrials.gov, number NCT02662231. Findings: Between Jan 4, 2016, and July 31, 2016, 13 265 records were submitted for analysis. 12 539 patients from 343 hospitals in 66 countries were included. 7339 (58·5%) patient were from high-HDI countries (193 hospitals in 30 countries), 3918 (31·2%) patients were from middle-HDI countries (82 hospitals in 18 countries), and 1282 (10·2%) patients were from low-HDI countries (68 hospitals in 18 countries). In total, 1538 (12·3%) patients had SSI within 30 days of surgery. The incidence of SSI varied between countries with high (691 [9·4%] of 7339 patients), middle (549 [14·0%] of 3918 patients), and low (298 [23·2%] of 1282) HDI (p < 0·001). The highest SSI incidence in each HDI group was after dirty surgery (102 [17·8%] of 574 patients in high-HDI countries; 74 [31·4%] of 236 patients in middle-HDI countries; 72 [39·8%] of 181 patients in low-HDI countries). Following risk factor adjustment, patients in low-HDI countries were at greatest risk of SSI (adjusted odds ratio 1·60, 95% credible interval 1·05–2·37; p=0·030). 132 (21·6%) of 610 patients with an SSI and a microbiology culture result had an infection that was resistant to the prophylactic antibiotic used. Resistant infections were detected in 49 (16·6%) of 295 patients in high-HDI countries, in 37 (19·8%) of 187 patients in middle-HDI countries, and in 46 (35·9%) of 128 patients in low-HDI countries (p < 0·001). Interpretation: Countries with a low HDI carry a disproportionately greater burden of SSI than countries with a middle or high HDI and might have higher rates of antibiotic resistance. In view of WHO recommendations on SSI prevention that highlight the absence of high-quality interventional research, urgent, pragmatic, randomised trials based in LMICs are needed to assess measures aiming to reduce this preventable complication

Anti-angiogenic and anti-proliferative activity of ziziphus leaf extract as a novel potential therapeutic agent for reducing hepatic injury in experimental hamster schistosomiasis.

BackgroundSchistosomiasis is one of the most prevalent helminthic infections worldwide. Praziquantel (PZQ) resistance poses a possible danger to the disease's ability to be controlled. Little is known about the role of Ziziphus spina-christi leaf extract (ZLE) in the treatment of hepatic schistosomiasis. However, no study has explored ZLE's anti-angiogenic and anti-proliferative activity as a possible mechanism for reducing hepatic injury in this context. Therefore, this study aimed to evaluate the therapeutic potential of ZLE as an anti-angiogenic, and anti-proliferative agent in hamsters infected with S. mansoni.MethodsFifty hamsters were used and divided into 5 groups (10 hamsters each); noninfected untreated (controls), noninfected treated with ZLE, infected untreated, infected treated with PZQ- and infected treated with ZLE. Anti-angiogenic and anti-fibrotic effects of the drugs were assessed pathologically through the immunohistochemical expression of VEGF, Ki-67, and TGF β1 in liver sections. Some oxidative stress parameters were measured in hepatic homogenates (NO, GSH, GST, and SOD), and serum liver enzymes were also assessed.ResultsA significant decrease in worm burden, granuloma size, granuloma area, and numbers in the ZLE- and PZQ-treated groups compared to the infected untreated group, and the decrease in granulomas number and tissue egg load was significantly lower in PZQ treated group compared to ZLE treated group (pConclusionOur results point to ZLE as a promising hepatoprotective therapeutic tool in the treatment of schistosome hepatic fibrosis as it has anti-angiogenic, anti-proliferative, anti-fibrotic, and antioxidant effects in hamsters infected with S. mansoni, providing scientific support for its use in conventional medicine

Experimental and numerical prediction of wetting fronts size created by sub-surface bubble irrigation system

A bubble irrigation system (BIS) is a subsurface irrigation method recently introduced that may provide a better mechanism in terms of flow regulation, as it involves mainly the exchange of water and air bubbles under slight negative pressure. The negative pressure flow was created using inverted closed plastic bottles (ICPB) that connected to an elevated closed tank. Understanding the characteristics of wetting fronts is key in designing this irrigation system. This paper mainly presents the principles of BIS, the experimental measurements and software simulation of BIS wetting patterns, and the development of statistical models for BIS wetting patterns dimensions estimation. Laboratory experiments were accomplished to measure the BIS’s sharp-wetting fronts variation with four diameters of contact areas of ICPB and two different soil types, namely SS1 and SS2. In addition, numerical simulations using a 2D HYDRUS were performed to explore the possibility of using the simulated non-sharp wetting fronts in predicting BIS wetting fronts. The experimental results and numerical simulations show that the soil properties and the area of contact have a significant impact on the bubble flow rate and the shape and size of the wetting patterns. The hydraulic conductivity and the density of soil SS2, which were 62 and 22 percent, respectively, higher than soil SS1, have resulted in average incremental ratios of wetted depth and width by 94 and 178 percent, respectively. Results also show that more than 50 percent of the growth of wetting fronts’ width and depth occurred rapidly at the early portion of irrigation time before flattening at the latter time, indicating the effectiveness of the air–water exchange in regulating the amount of water supplied and in controlling wetting fronts propagation. Furthermore, based on experimental and simulation results, regression models have been developed for estimation of bubble flow rates and the size of wetting fronts. The developed models can be reliably used to predict the bubble flow rate and size of wetting patterns with high accuracy

In Situ Preparation of Novel Porous Nanocomposite Hydrogel as Effective Adsorbent for the Removal of Cationic Dyes from Polluted Water

The use of some hydrogels as adsorbents for pollutants removal from wastewater is limited due to their high swelling properties and the difficulty in recovering them after the adsorption process. To overcome these problems, a new hydrogel nanocomposite based on chitosan-grafted-polyacrylic acid/oxidized electrospun carbon nanofibers (CT-g-PAA/O-ECNFs) was prepared by an in situ grafting polymerization process. The prepared hydrogel nanocomposite was used as a novel effective and highly reusable adsorbent for the removal of methylene blue (MB) from polluted water with low cost. The morphology and the structure of CT-g-PAA/O-ECNFs were investigated by numerous techniques. The effect of incorporating O-ECNFs on the swelling capability of the prepared hydrogel was explored in distillated water and MB solution at normal pH. The effect of parameters including ratio of O-ECNFs, contact time, pH, initial concentration, and temperature on adsorption process were explored. The adsorption isotherm and kinetic were studied by numerous non-linear models. The obtained results confirmed that the incorporation of O-ECNFs into the hydrogel network decreased the swelling capacity and improved its ability towards MB dye removal. The adsorption process depended on the pH value of the dye solution. Additionally, the adsorption and kinetic results were fitted using the Freundlich isotherm model and pseudo second order model (PSO), respectively. Moreover, the new adsorbents can be recycled for at least five cycles keeping its adsorption capacity and can be easily recovered without loss in its initial weight

Modeling the Uniformity of Manifold with Various Configurations

The flow distribution in manifolds is highly dependent on inlet pressure, configuration, and total inlet flow to the manifold. The flow from a manifold has many applications and in various fields of engineering such as civil, mechanical, and chemical engineering. In this study, physical and numerical models were employed to study the uniformity of the flow distribution from manifold with various configurations. The physical model consists of main manifold with uniform longitudinal section having diameter of 10.16 cm (4 in), five laterals with diameter of 5.08 cm (2 in), and spacing of 22 cm. Different inlet flows were tested and the values of these flows are 500, 750, and 1000 L/min. A manifold with tapered longitudinal section having inlet diameters of 10.16 cm (4 in) and dead end diameter of 5.08 cm (2 in) with the same above later specifications and flow rates was tested for its uniformity too. The percentage of absolute mean deviation for manifold with uniform diameter was found to be 34% while its value for the manifold with nonuniform diameter was found to be 14%. This result confirms the efficiency of the nonuniform distribution of fluids