Flexible and scalable software defined radio based testbed for large scale body movement

Human activity (HA) sensing is becoming one of the key component in future healthcare system. The prevailing detection techniques for IHA uses ambient sensors, cameras and wearable devices that primarily require strenuous deployment overheads and raise privacy concerns as well. This paper proposes a novel, non-invasive, easily-deployable, flexible and scalable test-bed for identifying large-scale body movements based on Software Defined Radios (SDRs). Two Universal Software Radio Peripheral (USRP) models, working as SDR based transceivers, are used to extract the Channel State Information (CSI) from continuous stream of multiple frequency subcarriers. The variances of amplitude information obtained from CSI data stream are used to infer daily life activities. Different machine learning algorithms namely K-Nearest Neighbour, Decision Tree, Discriminant Analysis and Naïve Bayes are used to evaluate the overall performance of the test-bed. The training, validation and testing processes are performed by considering the time-domain statistical features obtained from CSI data. The K-nearest neighbour outperformed all aforementioned classifiers, providing an accuracy of 89.73%. This preliminary non-invasive work will open a new direction for design of scalable framework for future healthcare systems

An Intelligent Non-Invasive Real-Time Human Activity Recognition System for Next-Generation Healthcare

Human motion detection is getting considerable attention in the field of Artificial Intelligence (AI) driven healthcare systems. Human motion can be used to provide remote healthcare solutions for vulnerable people by identifying particular movements such as falls, gait and breathing disorders. This can allow people to live more independent lifestyles and still have the safety of being monitored if more direct care is needed. At present wearable devices can provide real-time monitoring by deploying equipment on a person’s body. However, putting devices on a person’s body all the time makes it uncomfortable and the elderly tend to forget to wear them, in addition to the insecurity of being tracked all the time. This paper demonstrates how human motions can be detected in a quasi-real-time scenario using a non-invasive method. Patterns in the wireless signals present particular human body motions as each movement induces a unique change in the wireless medium. These changes can be used to identify particular body motions. This work produces a dataset that contains patterns of radio wave signals obtained using software-defined radios (SDRs) to establish if a subject is standing up or sitting down as a test case. The dataset was used to create a machine learning model, which was used in a developed application to provide a quasi-real-time classification of standing or sitting state. The machine-learning model was able to achieve 96.70% accuracy using the Random Forest algorithm using 10 fold cross-validation. A benchmark dataset of wearable devices was compared to the proposed dataset and results showed the proposed dataset to have similar accuracy of nearly 90%. The machine-learning models developed in this paper are tested for two activities but the developed system is designed and applicable for detecting and differentiating x number of activities

Software Defined Radio Based Testbed for Large Scale Body Movements

Monitoring Activities of Daily Livings (ADLs) has opened doors for numerous applications including patient monitoring, search & rescue, intrusion detection and so on. However, the parameterssuch as operating frequency, transmitting power, and antenna design are static where each application requires particular hardware applications. This paper lays the foundation for ADLs and presents the design of the testbed based on Universal Software Radio Peripheral (USRP) in conjunction with omni directional antenna, that can be used for detecting large scale body movements such as walking, sitting, standing, and critical events such as falls and small-scale movements. The core idea is to extract the channel state information (CSI) from the received signal since each body motion produces a unique CSI signature. In this context, we have performed various human activities such as walking, sitting on a chair etc. in indoor environment using two USRPs. The experimental results indicate that each body motion can be visually identified by examining the CSI data

COMPARATIVE STUDY OF A BIOPESTICIDE WITH SOME SYNTHETIC PESTICIDES USED AGAINST MUSTARD APHIDS (Lipephis erysimi Kalt)

ABSTRACT The experiment was conducted to compare effectiveness of (BtA) Bacillus thuringiensis and Abamectin @ 1gm/l with chlorpyrifos @ 5ml/l, megamos @ 1.25 ml/l and trend @ 4ml/l in controlling aphids (Lipaphis erysimi) on mustard (Eruca sativa) at Agricultural Research Farm, NWFP Agricultural University, Peshawar during 2004-05. These compounds were first sprayed to the point of runoff when the density of the aphids reached to 10 per leaf and repeated at 15 days after the first spray. There were 5 treatments along with one control and replicated 4 times. On mustard after two sprays all the pesticides (being non significant from one another) resulted in significant control of aphids over the check. Mean yield of mustard seed was significantly higher in chlorpyrifos treatment with 581 kg/ha, against 477 kg/ha in BtA treatment

p62-Keap1-NRF2-ARE Pathway: A Contentious Player for Selective Targeting of Autophagy, Oxidative Stress and Mitochondrial Dysfunction in Prion Diseases

Prion diseases are a group of fatal and debilitating neurodegenerative diseases affecting humans and animal species. The conversion of a non-pathogenic normal cellular protein (PrPc) into an abnormal infectious, protease-resistant, pathogenic form prion protein scrapie (PrPSc), is considered the etiology of these diseases. PrPSc accumulates in the affected individual’s brain in the form of extracellular plaques. The molecular pathways leading to neuronal cell death in prion diseases are still unclear. The free radical damage, oxidative stress and mitochondrial dysfunction play a key role in the pathogenesis of the various neurodegenerative disorders including prion diseases. The brain is very sensitive to changes in the redox status. It has been demonstrated that PrPc behaves as an antioxidant, while the neurotoxic prion peptide PrPSc increases hydrogen peroxide toxicity in the neuronal cultures leading to mitochondrial dysfunction and cell death. The nuclear factor erythroid 2-related factor 2 (NRF2) is an oxidative responsive pathway and a guardian of lifespan, which protect the cells from free radical stress-mediated cell death. The reduced glutathione, a major small molecule antioxidant present in all mammalian cells, and produced by several downstream target genes of NRF2, counterbalances the mitochondrial reactive oxygen species (ROS) production. In recent years, it has emerged that the ubiquitin-binding protein, p62-mediated induction of autophagy, is crucial for NRF2 activation and elimination of mitochondrial dysfunction and oxidative stress. The current review article, focuses on the role of NRF2 pathway in prion diseases to mitigate the disease progression

Machine Learning Driven Approach Towards the Quality Assessment of Fresh Fruits Using Non-invasive Sensing

In agriculture science, accurate information of moisture content (MC) in fruits and vegetables in an automated fashion can be vital for astute quality and grading evaluation. This demands for a viable, feasible and cost-effective technique for the defect recognition using timely detection of MC in fruits and vegetables to maintain a healthy sensory characteristic of fruits. Here we propose a non-invasive machine learning (ML) driven technique to monitor variations of MC in fruits using the terahertz (THz) waves with Swissto12 material characterization kit (MCK) in the frequency range of 0.75 THz to 1.1 THz. In this regard, multi-domain features are extracted from time-, frequency-, and time-frequency domains, and applied three ML algorithms such as support vector machine (SVM), knearest neighbour (KNN) and Decision Tree (D-Tree) for the precise assessment of MC in both apple and mango slices. The results illustrated that the performance of SVM exceeded other classifiers results using 10-fold validation and leave-oneobservation-out-cross-validation techniques. Moreover, all three classifiers exhibited 100 accuracy for day 1 and 4 with 80% MC value (freshness) and 2% MC value (staleness) of both fruits’ slices, respectively. Similarly, for day 2 and 3, an accuracy of 95% was achieved with intermediate MC values in both fruits’ slices. This study will pave a new direction for the real-time quality evaluation of fruits in a non-invasive manner by incorporating ML with THz sensing at a cellular level. It also has a strong potential to optimize economic benefits by the timely detection of fruits quality in an automated fashion

An Ongoing Futuristic Career of Metal–Organic Frameworks and Ionic Liquids, A Magical Gateway to Capture CO₂; A Critical Review

Carbon capture and storage (CCS) technologies are the “knight in shining armor” that can save humanity from burnout in the longer term, minimizing damage from CO2 emissions by keeping them out of the atmosphere. Metal–organic frameworks (MOFs) have received a promising career for CO2 capture due to their high porosity, surface area, excellent metal-to-ligand interaction, and good affinity to capture CO2 molecules. On the other hand, Ionic liquids (ILs) as emerging solvents have reported a significant influence on CO2 solubility due to their wide range of tunability in the selection of a variety of cations and anions along with the advantage of nonvolatility, high thermal stability, and nonflammability. The current Review highlights the recent progress and ongoing careers of employing MOFs and ILs in carbon capture technologies before their commercialization on a large scale. A brief overview of CO2 capturing using MOFs and ILs is given under the influence of their possible functionalization to enhance their CO2 separation. Information on the possible integration of MOFs-ILs as a composite system or membrane-based gas separation is also presented in detail. The integration has a high potential to capture CO2 while minimizing the unit operation costs for a stable, efficient, and smooth industrial gas separation operation. Present work attempts to link the chemistry of MOF and IL and their successful hybridization (MOF-IL composite) to process the economics for CO2 capture

Spatial, temporal, and demographic patterns in prevalence of chewing tobacco use in 204 countries and territories, 1990-2019 : a systematic analysis from the Global Burden of Disease Study 2019

Interpretation Chewing tobacco remains a substantial public health problem in several regions of the world, and predominantly in south Asia. We found little change in the prevalence of chewing tobacco use between 1990 and 2019, and that control efforts have had much larger effects on the prevalence of smoking tobacco use than on chewing tobacco use in some countries. Mitigating the health effects of chewing tobacco requires stronger regulations and policies that specifically target use of chewing tobacco, especially in countries with high prevalence. Findings In 2019, 273 center dot 9 million (95% uncertainty interval 258 center dot 5 to 290 center dot 9) people aged 15 years and older used chewing tobacco, and the global age-standardised prevalence of chewing tobacco use was 4 center dot 72% (4 center dot 46 to 5 center dot 01). 228 center dot 2 million (213 center dot 6 to 244 center dot 7; 83 center dot 29% [82 center dot 15 to 84 center dot 42]) chewing tobacco users lived in the south Asia region. Prevalence among young people aged 15-19 years was over 10% in seven locations in 2019. Although global agestandardised prevalence of smoking tobacco use decreased significantly between 1990 and 2019 (annualised rate of change: -1 center dot 21% [-1 center dot 26 to -1 center dot 16]), similar progress was not observed for chewing tobacco (0 center dot 46% [0 center dot 13 to 0 center dot 79]). Among the 12 highest prevalence countries (Bangladesh, Bhutan, Cambodia, India, Madagascar, Marshall Islands, Myanmar, Nepal, Pakistan, Palau, Sri Lanka, and Yemen), only Yemen had a significant decrease in the prevalence of chewing tobacco use, which was among males between 1990 and 2019 (-0 center dot 94% [-1 center dot 72 to -0 center dot 14]), compared with nine of 12 countries that had significant decreases in the prevalence of smoking tobacco. Among females, none of these 12 countries had significant decreases in prevalence of chewing tobacco use, whereas seven of 12 countries had a significant decrease in the prevalence of tobacco smoking use for the period. Summary Background Chewing tobacco and other types of smokeless tobacco use have had less attention from the global health community than smoked tobacco use. However, the practice is popular in many parts of the world and has been linked to several adverse health outcomes. Understanding trends in prevalence with age, over time, and by location and sex is important for policy setting and in relation to monitoring and assessing commitment to the WHO Framework Convention on Tobacco Control. Methods We estimated prevalence of chewing tobacco use as part of the Global Burden of Diseases, Injuries, and Risk Factors Study 2019 using a modelling strategy that used information on multiple types of smokeless tobacco products. We generated a time series of prevalence of chewing tobacco use among individuals aged 15 years and older from 1990 to 2019 in 204 countries and territories, including age-sex specific estimates. We also compared these trends to those of smoked tobacco over the same time period. Findings In 2019, 273 & middot;9 million (95% uncertainty interval 258 & middot;5 to 290 & middot;9) people aged 15 years and older used chewing tobacco, and the global age-standardised prevalence of chewing tobacco use was 4 & middot;72% (4 & middot;46 to 5 & middot;01). 228 & middot;2 million (213 & middot;6 to 244 & middot;7; 83 & middot;29% [82 & middot;15 to 84 & middot;42]) chewing tobacco users lived in the south Asia region. Prevalence among young people aged 15-19 years was over 10% in seven locations in 2019. Although global age standardised prevalence of smoking tobacco use decreased significantly between 1990 and 2019 (annualised rate of change: -1 & middot;21% [-1 & middot;26 to -1 & middot;16]), similar progress was not observed for chewing tobacco (0 & middot;46% [0 & middot;13 to 0 & middot;79]). Among the 12 highest prevalence countries (Bangladesh, Bhutan, Cambodia, India, Madagascar, Marshall Islands, Myanmar, Nepal, Pakistan, Palau, Sri Lanka, and Yemen), only Yemen had a significant decrease in the prevalence of chewing tobacco use, which was among males between 1990 and 2019 (-0 & middot;94% [-1 & middot;72 to -0 & middot;14]), compared with nine of 12 countries that had significant decreases in the prevalence of smoking tobacco. Among females, none of these 12 countries had significant decreases in prevalence of chewing tobacco use, whereas seven of 12 countries had a significant decrease in the prevalence of tobacco smoking use for the period. Interpretation Chewing tobacco remains a substantial public health problem in several regions of the world, and predominantly in south Asia. We found little change in the prevalence of chewing tobacco use between 1990 and 2019, and that control efforts have had much larger effects on the prevalence of smoking tobacco use than on chewing tobacco use in some countries. Mitigating the health effects of chewing tobacco requires stronger regulations and policies that specifically target use of chewing tobacco, especially in countries with high prevalence. Copyright (c) 2021 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license.Peer reviewe

Spatial, temporal, and demographic patterns in prevalence of smoking tobacco use and attributable disease burden in 204 countries and territories, 1990-2019 : a systematic analysis from the Global Burden of Disease Study 2019

Background Ending the global tobacco epidemic is a defining challenge in global health. Timely and comprehensive estimates of the prevalence of smoking tobacco use and attributable disease burden are needed to guide tobacco control efforts nationally and globally. Methods We estimated the prevalence of smoking tobacco use and attributable disease burden for 204 countries and territories, by age and sex, from 1990 to 2019 as part of the Global Burden of Diseases, Injuries, and Risk Factors Study. We modelled multiple smoking-related indicators from 3625 nationally representative surveys. We completed systematic reviews and did Bayesian meta-regressions for 36 causally linked health outcomes to estimate non-linear dose-response risk curves for current and former smokers. We used a direct estimation approach to estimate attributable burden, providing more comprehensive estimates of the health effects of smoking than previously available. Findings Globally in 2019, 1.14 billion (95% uncertainty interval 1.13-1.16) individuals were current smokers, who consumed 7.41 trillion (7.11-7.74) cigarette-equivalents of tobacco in 2019. Although prevalence of smoking had decreased significantly since 1990 among both males (27.5% [26. 5-28.5] reduction) and females (37.7% [35.4-39.9] reduction) aged 15 years and older, population growth has led to a significant increase in the total number of smokers from 0.99 billion (0.98-1.00) in 1990. Globally in 2019, smoking tobacco use accounted for 7.69 million (7.16-8.20) deaths and 200 million (185-214) disability-adjusted life-years, and was the leading risk factor for death among males (20.2% [19.3-21.1] of male deaths). 6.68 million [86.9%] of 7.69 million deaths attributable to smoking tobacco use were among current smokers. Interpretation In the absence of intervention, the annual toll of 7.69 million deaths and 200 million disability-adjusted life-years attributable to smoking will increase over the coming decades. Substantial progress in reducing the prevalence of smoking tobacco use has been observed in countries from all regions and at all stages of development, but a large implementation gap remains for tobacco control. Countries have a dear and urgent opportunity to pass strong, evidence-based policies to accelerate reductions in the prevalence of smoking and reap massive health benefits for their citizens. Copyright (C) 2021 The Author(s). Published by Elsevier Ltd.Peer reviewe

The global burden of cancer attributable to risk factors, 2010-19 : a systematic analysis for the Global Burden of Disease Study 2019

Background Understanding the magnitude of cancer burden attributable to potentially modifiable risk factors is crucial for development of effective prevention and mitigation strategies. We analysed results from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 to inform cancer control planning efforts globally. Methods The GBD 2019 comparative risk assessment framework was used to estimate cancer burden attributable to behavioural, environmental and occupational, and metabolic risk factors. A total of 82 risk-outcome pairs were included on the basis of the World Cancer Research Fund criteria. Estimated cancer deaths and disability-adjusted life-years (DALYs) in 2019 and change in these measures between 2010 and 2019 are presented. Findings Globally, in 2019, the risk factors included in this analysis accounted for 4.45 million (95% uncertainty interval 4.01-4.94) deaths and 105 million (95.0-116) DALYs for both sexes combined, representing 44.4% (41.3-48.4) of all cancer deaths and 42.0% (39.1-45.6) of all DALYs. There were 2.88 million (2.60-3.18) risk-attributable cancer deaths in males (50.6% [47.8-54.1] of all male cancer deaths) and 1.58 million (1.36-1.84) risk-attributable cancer deaths in females (36.3% [32.5-41.3] of all female cancer deaths). The leading risk factors at the most detailed level globally for risk-attributable cancer deaths and DALYs in 2019 for both sexes combined were smoking, followed by alcohol use and high BMI. Risk-attributable cancer burden varied by world region and Socio-demographic Index (SDI), with smoking, unsafe sex, and alcohol use being the three leading risk factors for risk-attributable cancer DALYs in low SDI locations in 2019, whereas DALYs in high SDI locations mirrored the top three global risk factor rankings. From 2010 to 2019, global risk-attributable cancer deaths increased by 20.4% (12.6-28.4) and DALYs by 16.8% (8.8-25.0), with the greatest percentage increase in metabolic risks (34.7% [27.9-42.8] and 33.3% [25.8-42.0]). Interpretation The leading risk factors contributing to global cancer burden in 2019 were behavioural, whereas metabolic risk factors saw the largest increases between 2010 and 2019. Reducing exposure to these modifiable risk factors would decrease cancer mortality and DALY rates worldwide, and policies should be tailored appropriately to local cancer risk factor burden. Copyright (C) 2022 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license.Peer reviewe