Projeto de criação de empresa no segmento de distribuição de GLP em Cascavel

Orientador: Zaki Akel SobrinhoMonografia(Especialização) - Universidade Federal do Paraná,Setor de Ciências Sociais Aplicadas, Curso de Especialização em Marketing EmpresarialInclui referênciasResumo: O mercado competitivo de distribuição de GLP cada vez mais exige ações inovadoras e meios diferentes de despertar o desejo do consumidor em escolher a sua empresa e não as demais existentes no mercado. E característico do mercado segundo a pesquisa de mercado realizada que a grande maioria dos consumidores não reconhece a marca das distribuidoras de GLP, que falta um compromisso ou atrativo maior para prender o consumidor a uma revenda de gás. Este projeto de viabilidade tem como objetivos específicos fixar a marca da revenda de gás como fornecedora de gás com alta qualidade e segurança, desenvolver a formação de um database marketing dos clientes, conhecer as expectativas do mercado de Cascavel com relações ao atendimento personalizado para o desenvolvimento de relacionamento duradouro com os clientes, coletar dados de qualificação do perfil dos consumidores e estimular o hábito de compra programada. Desta forma a Revenda de Gás quer criar e manter a fidelidade dos clientes e ter uma base de consumidores no mercado de Cascavel

Why Chloroplasts and Mitochondria Contain Genomes

Chloroplasts and mitochondria originated as bacterial symbionts. The larger, host cells acquired genetic information from their prokaryotic guests by lateral gene transfer. The prokaryotically-derived genes of the eukaryotic cell nucleus now function to encode the great majority of chloroplast and mitochondrial proteins, as well as many proteins of the nucleus and cytosol. Genes are copied and moved between cellular compartments with relative ease, and there is no established obstacle to successful import of any protein precursor from the cytosol. Yet chloroplasts and mitochondria have not abdicated all genes and gene expression to the nucleus and to cytosolic translation. What, then, do chloroplast- and mitochondrially-encoded proteins have in common that confers a selective advantage on the cytoplasmic location of their genes? The proposal advanced here is that co-location of chloroplast and mitochondrial genes with their gene products is required for rapid and direct regulatory coupling. Redox control of gene expression is suggested as the common feature of those chloroplast and mitochondrial proteins that are encoded in situ. Recent evidence is consistent with this hypothesis, and its underlying assumptions and predictions are described

ATP synthase: evolution, energetics, and membrane interactions

The synthesis of ATP, life's 'universal energy currency', is the most prevalent chemical reaction in biological systems, and is responsible for fueling nearly all cellular processes, from nerve impulse propagation to DNA synthesis. ATP synthases, the family of enzymes that carry out this endless task, are nearly as ubiquitous as the energy-laden molecule they are responsible for making. The F-type ATP synthase (F-ATPase) is found in every domain of life, and is believed to predate the divergence of these lineages over 1.5 billion years ago. These enzymes have therefore facilitated the survival of organisms in a wide range of habitats, ranging from the deep-sea thermal vents to the human intestine. In this review, we present an overview of the current knowledge of the structure and function of F-type ATPases, highlighting several adaptations that have been characterized across taxa. We emphasize the importance of studying these features within the context of the enzyme's particular lipid environment: Just as the interactions between an organism and its physical environment shape its evolutionary trajectory, ATPases are impacted by the membranes within which they reside. We argue that a comprehensive understanding of the structure, function, and evolution of membrane proteins -- including ATP synthase -- requires such an integrative approach.Comment: Review article; 29 pages, 6 figures/1 tabl