The Physics of the B Factories

This work is on the Physics of the B Factories. Part A of this book contains a brief description of the SLAC and KEK B Factories as well as their detectors, BaBar and Belle, and data taking related issues. Part B discusses tools and methods used by the experiments in order to obtain results. The results themselves can be found in Part C

Epithelioid cell histiocytoma with SQSTM1-ALK fusion: a case report

Abstract Background Epithelioid cell histiocytoma (ECH), which is also known as epithelioid benign fibrous histiocytoma, has been classified as a rare variant of fibrous histiocytoma (FH). However, the recent detection of ALK protein expression and/or ALK gene rearrangement in ECH suggests that it might be biologically different from conventional FH. Case presentation A 27-year-old male presented with nodule on his left foot, which had been present for 5 years. A macroscopic examination revealed an exophytic, hyperkeratotic nodule on the dorsum of the left foot. Tumorectomy was performed, and a microscopic examination showed a subepidermal lesion composed of sheets of tumor cells with oval to round nuclei and ill-defined eosinophilic cytoplasm. The tumor cells were diffusely positive for factor XIIIa and ALK, but were negative for AE1/AE3 keratin, alpha-smooth muscle actin, CD30, CD34, CD68, PU.1, melan A, MITF, and S-100 protein. ALK immunostaining showed a diffuse cytoplasmic staining pattern. ALK fluorescence in situ hybridization demonstrated break-apart signals, which was suggestive of ALK rearrangement. A 5′-rapid amplification of cDNA ends assay detected SQSTM1-ALK fusion, in which exon 5 of the SQSTM1 gene was fused to exon 20 of the ALK gene. The patient was free from recurrence and distant metastasis at the 1-year of follow-up. Conclusion We were able to demonstrate the SQSTM1-ALK fusion gene in ECH. Practically, detecting immunopositivity for ALK and appropriate cell-lineage markers are the key to diagnosing ECH

スポーツ施設開放におけるトレーニング・測定室の現状 : 高精度体成分分析装置の活用・健康チェック表の結果

Although Japanese people have one of the highest life expectancies and standards of health in the world, diseases caused by life habits such as cancer, heart disease and cerebral hemorrhage rank highest as the cause of death, and the number of people who need medical treatment has also been increasing. It is anticipated that in 2020, one out of four people will be a person of advanced years, and that Japanese society will have to bear a lot of expenses for nursing care. In such a situation, Mukogawa Women\u27s University opens its sports facilities for its students and staff. In order to carry out a physically and mentally healthy campus life, the faculty members of the Department of Health and Sports have practiced activities for the purpose of extending healthy lives