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Elective Cancer Surgery in COVID-19-Free Surgical Pathways During the SARS-CoV-2 Pandemic: An International, Multicenter, Comparative Cohort Study.

Author: Aawsaj Y.
Abad Gurumeta A.
Abad-Motos A.
Abate E.
Abatini C.
Abbadessa F.
Abbas A. M.
Abbassi-Ghadi N.
Abbott D.
Abbott T.
Abd Elazeem H. A. S.
Abdalla M.
Abdallah M.
Abdel Al S.
Abdel Jalil R.
Abdeldayem H.
Abdelkader Salama I.
Abdelkarem M. M.
Abdelkarim M.
Abdelmajeed A.
Abdelrahman A.
Abdelrahman S.
Abdelsamed A.
Abdou M.
Abdulkareem A.
Abdulwahed E.
Abdur-Rahman L.
Abel M. K.
Abellan M.
Aboelkassem Ibrahim A.
Abosamak N. E.
Abou Chaar M. K.
Abou-Khalil J.
Abouassi A.
Aboulkassem H.
Abreu Da Silva A.
Abu J.
Abu Za'nouneh F. J.
Abu-Nayla I.
Abubakar A.
Acebes Garcia F.
Achalandabaso Boira M.
Acher A.
Acrich E.
Adamina M.
Adamoli L.
Addae-Boateng E.
Aderombi A.
Adeyeye A.
Adiamah A.
Adishesh M.
Agapov M.
Aggarwal A.
Aghayeva A.
Agilinko J.
Agnes A.
Agostini C.
Agoston P.
Agrawal A.
Agresta F.
Aguado H.
Aguilar Gonzalez M.
Aguzzoli L.
Ahad S.
Ahmadi N.
Ahmeidat A.
Ahn J. H.
Aiken T.
Aime A.
Ajlan A.
Akalin M.
Akaydin E.
Akeel N.
Akgor U.
Akhtar M. A.
Akhter Rahman M. M.
Akilli H.
Akin E.
Akkour K.
Akmenkalne L.
Al Abdallah M.
Al Awwad S.
Al Habes H.
Al Maadany F. S.
Al Raddadi R.
Al-Habib A.
Al-Habsi R.
Al-Ishaq Z.
Al-Khayal K.
Al-Masri M.
Al-Mohammad A.
Al-Mukhtar A.
Al-Najjar H.
Al-Omishy H.
Al-Sarireh B.
AL-Sayed M.
Al-Tamimi Y.
Alaa S.
AlAamer O.
Aladeojebi A.
Alam F.
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Alamri A.
Alanbuki A.
Alatar A.
Alawneh F.
Alazawi D.
Albertsmeier M.
Albi Martin B.
Alburakan A.
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Publication venue: J Clin Oncol
Publication date: 01/01/2020
Field of study

PURPOSE: As cancer surgery restarts after the first COVID-19 wave, health care providers urgently require data to determine where elective surgery is best performed. This study aimed to determine whether COVID-19-free surgical pathways were associated with lower postoperative pulmonary complication rates compared with hospitals with no defined pathway. PATIENTS AND METHODS: This international, multicenter cohort study included patients who underwent elective surgery for 10 solid cancer types without preoperative suspicion of SARS-CoV-2. Participating hospitals included patients from local emergence of SARS-CoV-2 until April 19, 2020. At the time of surgery, hospitals were defined as having a COVID-19-free surgical pathway (complete segregation of the operating theater, critical care, and inpatient ward areas) or no defined pathway (incomplete or no segregation, areas shared with patients with COVID-19). The primary outcome was 30-day postoperative pulmonary complications (pneumonia, acute respiratory distress syndrome, unexpected ventilation). RESULTS: Of 9,171 patients from 447 hospitals in 55 countries, 2,481 were operated on in COVID-19-free surgical pathways. Patients who underwent surgery within COVID-19-free surgical pathways were younger with fewer comorbidities than those in hospitals with no defined pathway but with similar proportions of major surgery. After adjustment, pulmonary complication rates were lower with COVID-19-free surgical pathways (2.2% v 4.9%; adjusted odds ratio [aOR], 0.62; 95% CI, 0.44 to 0.86). This was consistent in sensitivity analyses for low-risk patients (American Society of Anesthesiologists grade 1/2), propensity score-matched models, and patients with negative SARS-CoV-2 preoperative tests. The postoperative SARS-CoV-2 infection rate was also lower in COVID-19-free surgical pathways (2.1% v 3.6%; aOR, 0.53; 95% CI, 0.36 to 0.76). CONCLUSION: Within available resources, dedicated COVID-19-free surgical pathways should be established to provide safe elective cancer surgery during current and before future SARS-CoV-2 outbreaks

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Elective cancer surgery in COVID-19-free surgical pathways during the SARS-CoV-2 pandemic: An international, multicenter, comparative cohort study

Author: Aawsaj Y.
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Abad-Motos A.
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Whelan P.
Whisker L.
Whitehall E.
Whitmore H.
Wilkin R.
Wilkins A.
Williams G.
Williams J.
Williams K.
Williams M. A.
Williams T.
Williamson K.
Wilson M.
Wimberger P.
Wimmer A.
Winnand P.
Winter D.
Winter S.
Wolfer S.
Wong M. P. K.
Wong S.
Wong W. J.
Woodham A.
Woodun H.
Worku D.
Wright G.
Wullschleger M.
Wustrack R.
Xenaki S.
Xu M. J.
Xyda S. E.
Xynos E.
Yahaya A. S.
Yanez C.
Yang W.
Yassin N.
Ye G.
Yesantharao P.
Yesilyurt D.
Yetkin G.
Yiallourou A.
Yildirim A.
Yildiz A.
Ying Y.
Yip V.
Yordanov S.
Young R.
Yousof E. A.
Youssef A.
Youssef M.
Yuksel E.
Yurttas C.
Zacharoulis D.
Zafar S. N.
Zakai D.
Zakaria A. D.
Zakaria R.
Zakaria Z.
Zambelli M. F.
Zambon M.
Zamora L.
Zamvar V.
Zani S.
Zanotti S.
Zanus G.
Zapardiel I.
Zarabini A. G.
Zatecky J.
Zegarac M.
Zelic M.
Zeller N.
Zengin A. K.
Zerbib P.
Zervas K.
Zese M.
Zhang H.
Zivanovic M.
Zivkovic M.
Zizzo M.
Zografos C.
Zonta S.
Zorrilla Ortuzar J.
Zourntou S.
Zouzoulas D.
Zubaidi A.
Zullo A.
Publication venue: 'American Society of Clinical Oncology (ASCO)'
Publication date: 01/01/2021
Field of study

PURPOSE As cancer surgery restarts after the first COVID-19 wave, health care providers urgently require data to determine where elective surgery is best performed. This study aimed to determine whether COVID-19–free surgical pathways were associated with lower postoperative pulmonary complication rates compared with hospitals with no defined pathway. PATIENTS AND METHODS This international, multicenter cohort study included patients who underwent elective surgery for 10 solid cancer types without preoperative suspicion of SARS-CoV-2. Participating hospitals included patients from local emergence of SARS-CoV-2 until April 19, 2020. At the time of surgery, hospitals were defined as having a COVID-19–free surgical pathway (complete segregation of the operating theater, critical care, and inpatient ward areas) or no defined pathway (incomplete or no segregation, areas shared with patients with COVID-19). The primary outcome was 30-day postoperative pulmonary complications (pneumonia, acute respiratory distress syndrome, unexpected ventilation). RESULTS Of 9,171 patients from 447 hospitals in 55 countries, 2,481 were operated on in COVID-19–free surgical pathways. Patients who underwent surgery within COVID-19–free surgical pathways were younger with fewer comorbidities than those in hospitals with no defined pathway but with similar proportions of major surgery. After adjustment, pulmonary complication rates were lower with COVID-19–free surgical pathways (2.2% v 4.9%; adjusted odds ratio [aOR], 0.62; 95% CI, 0.44 to 0.86). This was consistent in sensitivity analyses for low-risk patients (American Society of Anesthesiologists grade 1/2), propensity score–matched models, and patients with negative SARS-CoV-2 preoperative tests. The postoperative SARS-CoV-2 infection rate was also lower in COVID-19–free surgical pathways (2.1% v 3.6%; aOR, 0.53; 95% CI, 0.36 to 0.76). CONCLUSION Within available resources, dedicated COVID-19–free surgical pathways should be established to provide safe elective cancer surgery during current and before future SARS-CoV-2 outbreaks

Archivio istituzionale della Ricerca - Università degli Studi di Parma

Area-Specific Synapse Structure in Branched Posterior Nucleus Axons Reveals a New Level of Complexity in Thalamocortical Networks

Author: Alonso-Nanclares Lidia
Casas-Torremocha D.
Clascá Francisco
DeFelipe Javier
Lübke J.H.R.
Merchán-Pérez Ángel
Porrero C.
Rodriguez-Moreno J.
Rollenhagen A.
Rubio-Teves M.
Santuy Muñoz Andrea
Yakoubi R.
Publication venue: 'Society for Neuroscience'
Publication date: 03/08/2020
Field of study

Thalamocortical posterior nucleus (Po) axons innervating the vibrissal somatosensory (S1) and motor (MC) cortices are key links in the brain neuronal network that allows rodents to explore the environment whisking with their motile snout vibrissae. Here, using fine-scale high-end 3D electron microscopy, we demonstrate in adult male C57BL/6 wild-type mice marked differences between MC versus S1 Po synapses in (1) bouton and active zone size, (2) neurotransmitter vesicle pool size, (3) distribution of mitochondria around synapses, and (4) proportion of synapses established on dendritic spines and dendritic shafts. These differences are as large, or even more pronounced, than those between Po and ventro-posterior thalamic nucleus synapses in S1. Moreover, using single-axon transfection labeling, we demonstrate that the above differences actually occur on the MC versus the S1 branches of individual Po cell axons that innervate both areas. Along with recently-discovered divergences in efficacy and plasticity, the synaptic structure differences reported here thus reveal a new subcellular level of complexity. This is a finding that upends current models of thalamocortical circuitry, and that might as well illuminate the functional logic of other branched projection axon systems.SIGNIFICANCE STATEMENT Many long-distance brain connections depend on neurons whose branched axons target separate regions. Using 3D electron microscopy and single-cell transfection, we investigated the mouse Posterior thalamic nucleus (Po) cell axons that simultaneously innervate motor and sensory areas of the cerebral cortex involved in whisker movement control. We demonstrate significant differences in the size of the boutons made in each area by individual Po axons, as well as in functionally-relevant parameters in the composition of their synapses. In addition, we found similarly large differences between the synapses of Po versus ventral posteromedial thalamic nucleus axons in the whisker sensory cortex. Area-specific synapse structure in individual axons implies a new, unsuspected level of complexity in long-distance brain connections

Digital.CSIC

The determination of earthquake location and magnitude from macroseismic data in Europe

Author: A Giesecke
A Johnston
A Udías
A. A. Gomez-Capera
A. Rovida
AA Gómez Capera
B Baptie
B Efron
C Pasolini
D Mayer-Rosa
D Stich
D. Viganò
DL Wells
E Baroux
E Buforn
EM Scordilis
F Bernardi
F Carletti
G Grünthal
H Bungum
J Batlló
J Havskov
J Mezcua
KG Hinzen
L Costantinescu
M Gisler
M Locati
M Meghraoui
M Stucchi
M. Stucchi
MA Torres-Vera
MC Oncescu
MS Sibol
NN Ambraseys
P Albini
P Gasperini
P Gasperini
P Hall
P Teves-Costa
P. Gasperini
R Azzaro
RMW Musson
RMW Musson
S Pondrelli
S Pondrelli
S Pondrelli
S Pondrelli
S Álvarez-Rubio
SL Sargeant
SP Vilanova
WH Bakun
WH Bakun
WH Bakun
Publication venue: 'Springer Science and Business Media LLC'
Publication date: 01/01/2015
Field of study

This paper describes how the earthquake parameters of historical earthquakes have been determined in Europe from macroseismic data by means of the so-called \u201cBoxer\u201d method, in the frame of the European Commission 2009\u20132012 Project SHARE (Seismic Hazard Harmonization in Europe). The problems related to the assessment of magnitude are described with more detail; the methodological issues are developed with special reference to the \u201cstable continental region\u201d. The paper first describes how the coefficients of the Boxer method are determined in five tectonic regions of the European area from the relevant calibration data sets, and discusses the problems dealt with while performing this task. Then it describes how the results have been checked against data different from those used in the previous phase. Finally, the application of the new coefficients to nearly a thousand of European earthquakes before 1900 is described. Stressing that, for the first time in Europe, homogeneous results have been obtained at such a large scale, the final part of the paper is devoted to analyse such results, with special reference to the general trends and to some case-histories

Crossref

Archivio istituzionale della ricerca - Alma Mater Studiorum Università di Bologna

The determination of earthquake location and magnitude from macroseismic data in Europe

Author: A Giesecke
A Johnston
A Udías
A. A. Gomez-Capera
A. Rovida
AA Gómez Capera
B Baptie
B Efron
C Pasolini
D Mayer-Rosa
D Stich
D. Viganò
DL Wells
E Baroux
E Buforn
EM Scordilis
F Bernardi
F Carletti
G Grünthal
H Bungum
J Batlló
J Havskov
J Mezcua
KG Hinzen
L Costantinescu
M Gisler
M Locati
M Meghraoui
M Stucchi
M. Stucchi
MA Torres-Vera
MC Oncescu
MS Sibol
NN Ambraseys
P Albini
P Gasperini
P Gasperini
P Hall
P Teves-Costa
P. Gasperini
R Azzaro
RMW Musson
RMW Musson
S Pondrelli
S Pondrelli
S Pondrelli
S Pondrelli
S Álvarez-Rubio
SL Sargeant
SP Vilanova
WH Bakun
WH Bakun
WH Bakun
Publication venue: 'Springer Science and Business Media LLC'
Publication date
Field of study

Crossref

Candida bloodstream infections in intensive care units: analysis of the extended prevalence of infection in intensive care unit study

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Abbruzzese C.
Abel P.
Abulmagd M.
Adén F.
Afonso S.
Aguilar G.
Aguilar L.
Aguirre G.
Alan Javier Z.
Alansary A.
Albaya A.
Aldrighi J.
Alemparte-Pardavila E.
Alhashemi J.
Alheira-Rocha R.
Ali A.
Almeida E.
Alvarez M.
Alves A.
Alves M.
Amador Amerigo J.
Amaro P.
Ambike D.
Amin P.
Ammann J.
Anane S.
Andrade C.
Angstwurm Matthias
Antonelli M.
Antón Caraballo E.
Arabi Y.
Arias Antun A.
Armaganidis A.
Arribas M.
Arroyo A.
Assuncao M.
Avila C.
Azoulay Elie
Azoulay Elie
Bach F.
Bakker J.
Bakondy R.
Bakshi C.
Balasini S.
Balciunas M.
Banerjee A.
Baptista M.
Barahona D.
Barbosa A.
Barbosa A.
Barcenilla-Gaite F.
Barry B.
Barsic B.
Bartkowska-Sniatkowska A.
Bartosik T.
Bass F.
Bassetti M.
Bassols A.
Bates J.
Beca J.
Becerra R.
Bechtold A.
Beer R.
Belohlavek J.
Benad H.
Berezowicz P.
Berghmans T.
Bergmans D.
Berlet T.
Bermudez Aceves E.
Bernardez D.
Bersten A.
Betsch H.
Bevilacqua C.
Bhagwanjee S.
Bhagwanjee S.
Bhome A.
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Bingold T.
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Bitencourt W.
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Deutschmann C.
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di Filippo A.
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Duranteau Jacques
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Dörr F.
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Eftimova B.
Eickmeyer H.
El-Dash S.
Emmi V.
Engel J.
Eric P.
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Extended Prevalence of Infection in ICU Study (EPIC II) Group of Investigators
Fang Li J.
Fantini M.
Farkas J.
Faybik P.
Febra C.
Feijó J.
Ferguson N.
Fernandez-Ponce O.
Fernández R.
Ferraro F.
Ferreira D.
Ferreira F.
Ferreira L.
Ferro L.
Festa M.
Fiedler F.
Filipescu D.
Filos K.
Filzwieser G.
Fiore G.
Firlinger F.
Firment J.
Fischer B.
Fischer F.
Fitzal S.
Fitzgerald R.
Fleury R.
Fogh B.
Forte D.
Forêt F.
Fraipont V.
Francois B.
Frans E.
França C.
Frederic V.
Freebairn R.
Freysz M.
Fricke G.
Friederich P.
Friedman G.
Friedrich T.
Fulgencio J.
Gabriel C.
Gadisseux P.
Galdos-Anuncibay P.
Gales M.
Galvez Ruiz J.
Galvez S.
Garba P.
Garcia Del Valle S.
Garcia F.
Garrigues B.
Garro P.
Gaszynski T.
Geiseler J.
Geldner G.
Gerlach Herwig
Germano A.
Gianesello L.
Giannellis C.
Giarratano A.
Gille A.
Giuseppe N.
Glaser M.
Gleissner J.
Glück T.
Goethe J. W.
Goethe J. W.
Goetz J.
Gomersall C.
Gomes A.
Gomez J.
Gonzalez Salazar F.
Goosen J.
Gopal P.
Goraj R.
Gornik I.
Gottwalles Y.
Govil D.
Granados M.
Greco S.
Green R.
Greive C.
Grigoras I.
Grilo M.
Grion C.
Grljusic M.
Groeneveld J.
Groeschel A.
Groves N.
Grozdanovski K.
Gründling Matthias
Guadagnucci A.
Guberti A.
Guerrero Gomez F.
Guerrero F.
Guerrero F.
Guimarães H.
Gullo A.
Guralnik V.
Gurjar M.
Gusu D.
Gutierrez Morales H.
Gutierrez P.
Guérin C.
Gérard J.
Harjola V.
Hartwig T.
Hashimoto Shunichi
Hatum R.
Hawker F.
Heffernan C.
Heinemeyer D.
Heintz M.
Helmes T.
Henn-Beilharz A.
Henneberg T.
Henning F.
Henry L.
Hering R.
Hermann C.
Herold I.
Herridge M.
Hidalgo J.
Hien S.
Hiesmayr M.
Hildegard J.
Hinz M.
Holland R.
Holst D.
Holubarsch T.
Hon P.
Hopf H.
Houly J.
Hovnanian A.
Huber T.
Huettemann E.
Huylenbroeck G.
Hájek R.
Hérvé O.
Ibañez A.
Ibrahim A.
Idris N.
Iglesias Fraile L.
Ihle B.
Ikeda T.
Ilutovich S.
Imanaka H.
Insausti J.
Ioannidou E.
Iolster T.
Ionita V.
Iraola Ferrer M.
Iyer S.
Jacek K.
Jacobs F.
Jacobsen Klaus Uwe
Jani C.
Jankovic R.
Jannello G.
Janssens U.
Japiassú A.
Japiassú A.
Jaschinski Ulrich
Javed I.
Jelen-Esselborn S.
Jensen Niels-Henrik
Jibaja M.
Jing Y.
Joannes-Boyau O.
Joannidis M.
Jog S.
Jokiel M.
Jorda R.
Jordan F.
Joseph R.
Jost V.
João H. S.
João S.
Julien H.
Junker A.
Jürgen B.
Kaisers Udo
Kalkoff M.
Kapadia F.
Karampela I.
Karipparambath V.
Karpel E.
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Publication venue: 'Ovid Technologies (Wolters Kluwer Health)'
Publication date: 01/01/2011
Field of study

Item does not contain fulltextOBJECTIVES: To provide a global, up-to-date picture of the prevalence, treatment, and outcomes of Candida bloodstream infections in intensive care unit patients and compare Candida with bacterial bloodstream infection. DESIGN: A retrospective analysis of the Extended Prevalence of Infection in the ICU Study (EPIC II). Demographic, physiological, infection-related and therapeutic data were collected. Patients were grouped as having Candida, Gram-positive, Gram-negative, and combined Candida/bacterial bloodstream infection. Outcome data were assessed at intensive care unit and hospital discharge. SETTING: EPIC II included 1265 intensive care units in 76 countries. PATIENTS: Patients in participating intensive care units on study day. INTERVENTIONS: None. MEASUREMENT AND MAIN RESULTS: Of the 14,414 patients in EPIC II, 99 patients had Candida bloodstream infections for a prevalence of 6.9 per 1000 patients. Sixty-one patients had candidemia alone and 38 patients had combined bloodstream infections. Candida albicans (n = 70) was the predominant species. Primary therapy included monotherapy with fluconazole (n = 39), caspofungin (n = 16), and a polyene-based product (n = 12). Combination therapy was infrequently used (n = 10). Compared with patients with Gram-positive (n = 420) and Gram-negative (n = 264) bloodstream infections, patients with candidemia were more likely to have solid tumors (p < .05) and appeared to have been in an intensive care unit longer (14 days [range, 5-25 days], 8 days [range, 3-20 days], and 10 days [range, 2-23 days], respectively), but this difference was not statistically significant. Severity of illness and organ dysfunction scores were similar between groups. Patients with Candida bloodstream infections, compared with patients with Gram-positive and Gram-negative bloodstream infections, had the greatest crude intensive care unit mortality rates (42.6%, 25.3%, and 29.1%, respectively) and longer intensive care unit lengths of stay (median [interquartile range]) (33 days [18-44], 20 days [9-43], and 21 days [8-46], respectively); however, these differences were not statistically significant. CONCLUSION: Candidemia remains a significant problem in intensive care units patients. In the EPIC II population, Candida albicans was the most common organism and fluconazole remained the predominant antifungal agent used. Candida bloodstream infections are associated with high intensive care unit and hospital mortality rates and resource use

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Candida bloodstream infections in intensive care units: analysis of the extended prevalence of infection in intensive care unit study

Author: 't Kindt H
Abbruzzese C
Abel P
Abulmagd M
Ad\ue9n F
Adanir T
Afessa B
Afifi S
Afonso S
Agabani H
Aguilar G
Aguilar L
Aguirre G
Agvald Ohman C
Akan M
Akinci I
Al rahma H
Alan Javier Z
Alansary A
Albaya A
Albornoz H
Aldrighi J
Alemparte Pardavila E
Alhashemi J
Alheira Rocha R
Ali A
Almeida E
Alsabbah A
Alvarez M
Alves A
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Amador Amerigo J
Amaro P
Ambike D
Amin P
Ammann J
Ammons L
Anane S
Andrade C
Angstwurm M
Ant\uf3n Caraballo E
Antonelli M
Appadu B
Arabi Y
Arias Antun A
Armaganidis A
Arribas M
Arroyo A
Arvidsson S
Assuncao M
Atalan K
Ates C
Avila C
AZOULAY E
Azoulay E
B\ue1rtolo A
Bach F
Badr A
Bagnulo H
Bakker J
Bakondy R
Bakshi C
Balasini S
Balciunas M
Baldwin F
Banerjee A
Baptista M
Barahona D
Baraibar J
Barbosa A
Barbosa A
Barcenilla Gaite F
Barrera Groba C
Barrera groba C
Barry B
Barsic B
Bartkowska Sniatkowska A
Bartosik T
Bass F
BASSETTI MATTEO
Bassols A
Bates J
Beca J
Becerra R
Bechtold A
Beer R
Belohlavek J
Belzberg H
Benad H
Berezowicz P
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Bermudez Aceves E
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Betsch H
Bevilacqua C
Bewley J
Bhagwanjee S
Bhagwanjee S
Bhome A
Biancofiore G
Bingold T
Binning A
Biston P
Bitencourt W
Bitencourt W
Bittinger M
Bitzani M
Blahut L
Blanco Vicente A
Blank E
Blanloeil Y
Bleier H
Blesa Malpica A
Blom H
Blomqvist H
Blosser S
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Bodmann K
Bodur H
Bogdanski R
Booth M
Borelli M
Borg M
Borges M
Borrelli F
Bosnak M
Bothma P
Boulanger C
Bourgeois M
Bouw M
Boyden J
Bozzetti C
Braga M
Brand\ue3o da Silva N
Brandt W
Branson R
Breen D
Breyer M
Briegel J
Briones Lopez M
Bronchard R
Browne B
Bruhn A
Brunain J
Bruzzi de Carvalho F
Buckley T
Buehner U
Bui T
Bumbasirevic V
Burgue\uf1o Campi\uf1ez M
Burnstein R
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Chawla R
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Conte V
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Cook D
Copotoiu S
Coral M
Corea M
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Costa H
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Cottini S
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Crerar Gilbert A
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Cubrilo Turek M
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Restrepo M
Rezende A
Rhodes A
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Richards G
Rico Feijoo J
Riessen R
Rijckaert D
Rios Picaza G
Risch T
Rivera R
Roberto F
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Robinson S
Rocha M
Rodgers M
Rodriguez Gonzalez D
Rodriguez D
Rodriguez W
Roman A
Rosano A
Rosi R
Rosseel P
Rothhammer A
Routsi C
Rovira A
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Rubio O
Rudenstam J
Rudolph M
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Ruiz J
Rummo G
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Russell M
Rutsaert R
Ruyffelaere P
Ryan A
S\ue1nchez Olmedo J
Sad R
Sahu S
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Salgado D
Salgado E
Salluh J
Salmen Z
Samavedam S
Sanchez Garcia M
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Santagostino G
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Santos C
Santos I
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Shyam Sunder T
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Sole viol\ue1n J
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Soto Ib\ue1\uf1ez J
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Souza Dantas V
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Spapen H
Speelberg B
Spies C
Sprung C
Squara P
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Steingrub J
Stelian E
Stephanova L
Stepinska J
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Stocker R
Stolt C
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Treu T
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Tsarianski G
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Turkmen A
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Tyl D
Udwadia F
Udwadia F
Ugarte Pe\uf1a P
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Vegas Pinto R
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Villagomez A
Villela D
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VINCENT JL
Vincent JL
Voegeler S
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Vuylsteke A
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Z\uf6llei \uc9
Zahn P
Zakynthinos E
Zasmeta G
Zavala E
Zender H
Zhan Q
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Zhao Y
Zimmermann R
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Zuckermann Becker H
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Publication venue
Publication date: 01/01/2011
Field of study

To provide a global, up-to-date picture of the prevalence, treatment, and outcomes of Candida bloodstream infections in intensive care unit patients and compare Candida with bacterial bloodstream infection. DESIGN: A retrospective analysis of the Extended Prevalence of Infection in the ICU Study (EPIC II). Demographic, physiological, infection-related and therapeutic data were collected. Patients were grouped as having Candida, Gram-positive, Gram-negative, and combined Candida/bacterial bloodstream infection. Outcome data were assessed at intensive care unit and hospital discharge. SETTING: EPIC II included 1265 intensive care units in 76 countries. PATIENTS: Patients in participating intensive care units on study day. INTERVENTIONS: None. MEASUREMENT AND MAIN RESULTS: Of the 14,414 patients in EPIC II, 99 patients had Candida bloodstream infections for a prevalence of 6.9 per 1000 patients. Sixty-one patients had candidemia alone and 38 patients had combined bloodstream infections. Candida albicans (n = 70) was the predominant species. Primary therapy included monotherapy with fluconazole (n = 39), caspofungin (n = 16), and a polyene-based product (n = 12). Combination therapy was infrequently used (n = 10). Compared with patients with Gram-positive (n = 420) and Gram-negative (n = 264) bloodstream infections, patients with candidemia were more likely to have solid tumors (p < .05) and appeared to have been in an intensive care unit longer (14 days [range, 5-25 days], 8 days [range, 3-20 days], and 10 days [range, 2-23 days], respectively), but this difference was not statistically significant. Severity of illness and organ dysfunction scores were similar between groups. Patients with Candida bloodstream infections, compared with patients with Gram-positive and Gram-negative bloodstream infections, had the greatest crude intensive care unit mortality rates (42.6%, 25.3%, and 29.1%, respectively) and longer intensive care unit lengths of stay (median [interquartile range]) (33 days [18-44], 20 days [9-43], and 21 days [8-46], respectively); however, these differences were not statistically significant. CONCLUSION: Candidemia remains a significant problem in intensive care units patients. In the EPIC II population, Candida albicans was the most common organism and fluconazole remained the predominant antifungal agent used. Candida bloodstream infections are associated with high intensive care unit and hospital mortality rates and resource use

Archivio istituzionale della ricerca - Università degli Studi di Udine

Delaying surgery for patients with a previous SARS-CoV-2 infection

Author: A A Ali Karar
A A Kerawala
A A Marra
A Abad Gurumeta
A Abad-Motos
A Abdelmajeed
A Abdelrahman
A Abdelsamed
A Abdulkareem
A Aboelkassem Ibrahim
A Abouassi
A Abreu da Silva
A Abubakar
A Acher
A Aderombi
A Adeyeye
A Adiamah
A Aggarwal
A Aghayeva
A Agnes
A Agrawal
A Ahmeidat
A Aimé
A Ajlan
A Al-Habib
A Al-Mohammad
A Al-Mukhtar
A Aladeojebi
A Alamri
A Alanbuki
A Alatar
A Alburakan
A Alfaro-Goldaracena
A Alhamed
A Alhefdhi
A Almeciga
A Almeida
A Alomair
A Alonso Poza
A Alsaif
A Anastasi
A Antic
A Anzak
A Aprile
A Arminio
A Arulanantham
A Askari
A Asqalan
A Athanasiou
A Ayhan
A Ayman
A Ayubi
A Azizi
A B Martins
A Bacon
A Baker
A Balakrishnan
A Bandiera
A Banerjee
A Barrabe
A Beamish
A Bellacci
A Belli
A Belvedere
A Benkabbou
A Bhalla
A Bhangu
A Billè
A Bin Nasser
A Biondi
A Blatt
A Blazquez Martin
A Boddy
A Bokhari
A Bondurri
A Boulton
A Boutall
A Branquinho
A Brunelli
A Brunt
A Bruscino
A Budacan
A Burahee
A Böttcher
A C Almeida
A C Deus
A C Roslani
A C Soares
A C Vieira Paiva Lopes
A Caiado
A Camillo
A Canas-Martinez
A Cano
A Carabias
A Chandock
A Charalabopoulos
A Che Jusoh
A Chebaro
A Chessa
A Chiappini
A Chitul
A Choudhry
A Chowdhury
A Colquhoun
A Conesa
A Cordova
A Costanzi
A Cotoia
A Cotter
A Crichton
A Cuadrado-García
A Currie
A Cvetkovic
A D Bueno Cañones
A D Rajgor
A D Zakaria
A D'Amore
A D'Urso
A Daly
A Davies
A Day
A De Gea Rico
A De Manzoni Garberini
A De Pablo García-Cuenca
A De Troia
A De Virgilio
A Dehal
A Desai
A Di Bartolomeo
A Di Bella
A Di Somma
A Diamantis
A Doyle
A Durrani
A E Arikan
A E Sherif
A Eastmond
A El Ouahabi
A Elawad
A Eldaly
A Elhamshary
A Esposito
A Esteban
A Ezanno
A Fadzli
A Fagotti
A Fancellu
A Farsi
A Faustino
A Fazenda
A Fernández-López
A Ferrero
A Ferrés
A Fiorini
A Fisher
A Fletcher
A Fowler
A Fox
A Frampton
A Frankel
A Frati
A Freitas
A Frena
A Fuson
A G Carta
A G Zarabini
A Gabre-Kidan
A Gagliano
A Gainza
A Gatti
A Gattolin
A Gaunt
A Geddes
A Gegúndez Simón
A Ghanbari
A Ghannam
A Giaglaras
A Gianni
A Giblin
A Gillis
A Gklavas
A Glencer
A Gomes da Costa
A Gori
A Goyal
A Gronchi
A Gueutier
A Guglielmi
A Guimarães
A Gupta
A Gutierrez Calvo
A Gvaramadze
A Gómez-Pedraza
A H Hussain
A H Khan
A Habeeb
A Hainsworth
A Hamad
A Hannah
A Hanson
A Harky
A Hasenburg
A Hawkins
A Haynes
A Haynes
A Henry
A Herman
A Hernández Gutierrez
A Heuer
A Hmedat
A Hogan
A Hunt
A I Gutiérrez Fernández
A I Kilani
A I Soriano
A I Tercero-Uribe
A Ibrahim
A Ionescu
A Jah
A Jain
A Jamal
A Jibril
A Jiménez
A Joshi
A Jotic
A K Ali
A K Andrade
A K Lala
A K Scafa
A K Zengin
A Kahn
A Kamocka
A Kanatas
A Kappenberger
A Karamarkovic
A Karim
A Kattakayam
A Kaufmann
A Kawai
A Kent
A Khajuria
A Khan
A Khoja
A Kirk
A Kisiel
A Kler
A Kocataş
A Koh
A Kolias
A Kollàr
A Kolusarı
A Kourdouli
A Kouyoumdjian
A Kredan
A Kumar
A Königsrainer
A L De Oliveira López
A L Ebbehøj
A L Picardo
A Laforest
A Lagares
A Laios
A Laird
A Landaluce-Olavarria
A Lanzon
A Larentzakis
A Lauretta
A Lim
A Loayza
A Loehrer
A Lopez Abad
A Louvrier
A Lovece
A Lowery
A Lyons
A Lázaro
A López Campillo
A M Abbas
A M Baietti
A M Castaño-Leon
A M Correia
A M Lacy
A M Majbar
A M Minaya Bravo
A M Ntziovara
A M Pathanki
A M Perrone
A M Scanu
A Macchi
A Madhavan
A Madkhali
A Maffioli
A Maffuz-Aziz
A Maghrabi
A Maiga
A Majkowska
A Mansuri
A Mantevas
A Marano
A Marchbank
A Marco Garrido
A Margalit
A Martin-Ucar
A Martinez German
A Marçal
A Mashat
A Maw
A McCanny
A Mccarthy
A McLennan
A McMillan
A Melo
A Menon
A Merchan
A Merdrignac
A Miljković
A Millan
A Mingoli
A Minicozzi
A Mirabella
A Modabber
A Mohammad
A Moro
A Morris
A Morsi
A Morton
A Mosca
A Moumen
A Muratore
A Mustafa
A N Sanli
A Nabil
A Nakas
A Nawawi
A Nobre Pinto
A Nogués
A Oar
A Oliveira
A Osorio
A Otero
A Ovaitt
A P Ferreira Pinto
A P Pezzuto
A Parello
A Parente
A Parseliunas
A Patel
A Patel
A Paunovic
A Pearce
A Pereira
A Pereira-Neves
A Peryt
A Petrillo
A Piras
A Pisani Ceretti
A Pisanu
A Polydorou
A Popoola
A Porcu
A Provozina
A Pucar
A Pérez Núñez
A Qasem
A Quennell
A Qureshi
A Ramachandran
A Ramos Bonilla
A Ramwell
A Ribeiro
A Rizzi
A Robinson
A Robson
A Rodolakis
A Rodrigues
A Rodriguez Fraga
A Rogers
A Rogers
A Romero de Diego
A Rowcroft
A Ruivo
A Ruiz Escobar
A Ruzzenente
A S Bodla
A S Coonar
A S Crugnale
A S Memon
A S Mohamed Sidek
A S Yahaya
A Sabry
A Sachdeva
A Sagnotta
A Said Bayazeed
A Salamah
A Salazar
A Saleem
A Samih
A Samir Abdelaal
A Samkari
A Samy
A Santoro
A Sanz Larrainzar
A Saratziotis
A Sarin
A Sayasneh
A Scalabre
A Schache
A Seguin-Givelet
A Seleim
A Sgrò
A Shabana
A Sharkey
A Sharma
A Sheel
A Shenfine
A Sherif
A Shuwayyah
A Singh
A Soares
A Solth
A Souadka
A Spinelli
A Ssentongo
A Stanimirovic
A Stavroglou
A Stefanovic
A Stepanyan
A Subocius
A Sultana
A Sutherland
A Syllaios
A Sánchez-Pernaute
A Taddei
A Taibi
A Tailor
A Tang
A Tedde
A Thomas
A Thompson
A Tojal
A Tooulias
A Torne
A Torres
A Townson
A Trivic
A Tufo
A Turnbull
A Urbani
A Urbieta
A Usai
A Valente da Costa
A Vallance
A Valle Rubio
A Varazzani
A Vazquez Fernandez
A Vezakis
A Vieira
A Vignali
A Vitali
A Wali
A Wilkins
A Wimmer
A Woodham
A Y Azzam
A Yiallourou
A Yıldırım
A Yildiz
A Youssef
A Zubaidi
A Zullo
A Älgå
Abd Elazeem Has
Abhinav Tiwari
Abigail Vallance
Adesoji Ademuyiwa
Adesoji O Ademuyiwa
Adrian Marchbank
Ahmad Qureshi
Akshay Patel
Alan McNeill
Alessandro Brunelli
Alessandro Gronchi
Alex Alamri
Alex Wilkins
Alexandra Colquhoun
Alexis P Arnaud
Aman S Coonar
Amanpreet Brar
Ana Minaya-Bravo
Ana Minaya-Bravo
Ana Minaya-Bravo
Ana Minaya-Bravo
Anant Desai
Anant Desai
Andreas A Schnitzbauer
Andreas K Demetriades
Andrew G Schache
Andrew Knight
Andrew Loehrer
Andrew Schache
Andrey Litvin
Aneel A Bhangu
Aneel A Bhangu
Aneel Bhangu
Angelos Kolias
Angelos Kolias
Anna Fagotti
Antonino Spinelli
Antonio Ramos-De la Medina
April C Roslani
Arda Isik
Arnav Agarwal
B A Fahey
B Al-Sarireh
B Albi Martin
B Alhassan
B Ayub
B B Ozmen
B Baca
B Bakmaz
B Banky
B Barmayehvar
B Barrat
B Bartalucci
B Bozkırlı
B Brown
B Caimari
B Challacombe
B Chumbinho
B Cimenoglu
B Cirillo
B Citgez
B Collard
B Costeira
B Cros
B Davidson
B De Andrés Asenjo
B De Simone
B Devauchelle
B Dias
B Diéguez
B Díaz-Feijoo
B El Ahmadi
B Gil Ibañez
B Giray
B Gricks
B Griffiths
B Grotenhuis
B Gális
B Göksoy
B J Mehigan
B Jayasankar
B Johnston
B Kajmaković
B Keeler
B Kidane
B Knowles
B Kocer
B Kotlar
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B Martin-Perez
B McAree
B Narice
B Nunez-Garcia
B Patrício
B Pramodana
B Pérez-Saborido
B Rai
B S Kamera
B S Ong
B Seeliger
B Sheu
B Soyak
B Steel
B Swinson
B Tadic
B Thakur
B Ugarte-Sierra
B Vieira
B Vieira
B Wadham
Bandara Gbk
Benjamin Lamb
Brett E Dawson
Brittany K Bankhead-Kendall
C A Espinosa
C A Guariglia
C Abatini
C Agostini
C Allemand
C Alurralde
C Anthoulakis
C Arican
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C B Kulle
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C L Roland
C Langdon
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C M Chiesa-Estomba
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Carlos Jose Perez Rivera
Chai Akw
Chetan Khatri
Chris Bretherton
Christian Freyschlag
Christina Fotopoulou
Cioffi Spb
Conor S Jones
Constantine Halkias
Costa Mjma
D A Raptis
D Abbott
D Alazawi
D Angelou
D Attia
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D Barker
D Bekele
D Bergeat
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D Jones
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D M Donati
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D Miller
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D Mutter
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D Odetto
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D Parker
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D Phan
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D Rice
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D Rutherford
D Sanchez-Pelaez
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D Shrestha
D Sinha
D Sloothaak
D Snee
D Spalding
D Stavroulias
D Stevic
D Stojiljkovic
D Symeonidis
D T María Dolores
D Tartaglia
D Tatsis
D Tham
D Thekkinkattil
D Thompson
D Townend
D Tsolakidis
D Vatansever
D Veiga
D Velickovic
D Venskutonis
D Vervoort
D Vijayan
D Vimalachandran
D W Kjaer
D Walker
D Ward
D Watson
D West
D Winter
D Worku
D Yeşilyurt
D Z Khan
D Zacharoulis
D Zakai
D Zouzoulas
D Öfner
Dale Vimalachandran
Dale Vimalchandran
Daniel Cox
Daniel M Fountain
Daoud Chaudhry
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O Brown
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Piotr Major
Pronk Ajm
Q Ballouhey
R A Castillejos-Molina
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Richard Shaw
Richard Shaw
Risk Obf
Rob Bristow
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Ruth A Benson
Ruth Blanco-Colino
S A Güler
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S Abdel Al
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Salomone Di Saverio
Sameh Emile
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Samuel Ford
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T A Lawal
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T Kato
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T M Sorour
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T Vollkommer
T Walton
T Wasim
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T Williams
Tabassum Khan
Tatiana Garmanova
Thomas D Pinkney
Thomas Konney
Thomas M Drake
Tobias Klatte
Tom Ef Abbott
U Akgor
U Andaleeb
U Bork
U Bumbasirevic
U Butt
U De Andres Olabarria
U Fernandes
U Fumagalli Romario
U G Vo
U Grossi
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U M Jariod Ferrer
U Ribeiro Junior
U Ronellenfitsch
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U Speth
V Alexoudi
V Annessi
V Bascarevic
V Capizzi
V Chiarella
V Cozza
V D Mandato
V De Simone
V Devezas
V Drubay
V Duque-Mallén
V Fernandes
V Garcia Soria
V García Pineda
V Gata
V Granata
V H Baptista
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V J García Porcel
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V Jimenez
V Jokic
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V Konstantinovic
V Kubyshkin
V Lago
V Linz
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V Markovic
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V Mazzaferro
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V Miu
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V Ng
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V Quintodei
V Rizzo
V Rossi
V S Ban
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V Testa
V Tonini
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V Valbuena Jabares
V Valtzoglou
V Velchuru
V Vigorita
V Vujanac
V Yip
V Zamvar
V Šćepanović
Veeru Kasivisvanathan
W Butt
W Campbell
W Cymes
W Garrett
W H Khan
W J Wong
W Knight
W Lee
W Marx
W McCormick
W McGahan
W Mugla
W Oosterlinck
W Raby-Smith
W Smolka
W Van Houdt
W Yang
Willemijn van der Plas
Wong Mpk
X De Sousa
X Morales
X S Tan
Y Aawsaj
Y Al-Tamimi
Y Arkha
Y Ayasra
Y Bashir
Y El Bouazizi
Y Fayed
Y H Lam
Y Kanemitsu
Y Kara
Y Kirmizi
Y Levy-Zauberman
Y Litvina
Y Perez
Y T Liew
Y Tanase
Y Viswanath
Y Ying
Z Al-Ishaq
Z Aldayri
Z Aliyeva
Z Bayhan
Z Chia
Z Dzamic
Z H Belkhadir
Z Inic
Z Jawad
Z Jezdic
Z Katusic
Z Krivokapic
Z Lakkis
Z Li
Z M Barrett-Brown
Z Mahasin
Z Seymour
Z Vilendecic
Z Zakaria
Á De la Hoz Rodríguez
Á Fernández Camuñas
É Ryan
Ž Grubač
А Камалов
Publication venue: 'Wiley'
Publication date: 01/01/2020
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Archivio della ricerca - Università degli studi di Napoli Federico II

Veterinary medicine - Repository of PHD, master's thesis

Archivio della Ricerca - Università di Pisa

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Preoperative nasopharyngeal swab testing and postoperative pulmonary complications in patients undergoing elective surgery during the SARS-CoV-2 pandemic.

Author: Aawsaj Y
Abad Gurumeta A
Abad-Motos A
Abate E
Abatini C
Abbadessa F
Abbas AM
Abbassi-Ghadi N
Abbott D
Abbott T
Abbott TEF
Abd Elazeem HAS
Abdalla M
Abdallah M
Abdelaal SA
Abdeldayem H
Abdelkarem MM
Abdelkarim M
Abdelmajeed A
Abdelrahman A
Abdelrahman S
Abdelsamed A
Abdou M
Abdulkareem A
Abdulwahed E
Abdur-Rahman L
Abel MK
Abellan M
Abosamak NE
Abou Chaar MK
Abou-Khalil J
Abouassi A
Aboulkassem H
Abreu da Silva A
Abu Za'nouneh FJ
Abu J
Abu-Nayla I
Abubakar A
Abukhalaf S
Acebes Garcia F
Achalandabaso Boira M
Acher A
Acrich E
Adamina M
Adamina M
Adamoli L
Addae-Boateng E
Ademuyiwa AO
Aderombi A
Adeyeye A
Adiamah A
Adishesh M
Agapov M
Agarwal A
Aggarwal A
Aghayeva A
Agilinko J
Agnes A
Agostini C
Agoston P
Agrawal A
Agresta F
Aguado H
Aguzzoli L
Ahad S
Ahmadi N
Ahmed NR
Ahmeidat A
Ahn JH
Aiken T
Aime A
Ajlan A
Akalin M
Akaydin E
Akeel N
Akgor U
Akhtar MA
Akilli H
Akin E
Akkour K
Akkulak M
Akmenkalne L
Al Abdallah M
Al Abdel S
Al Awwad S
Al Habes H
Al Maadany FS
Al Raddadi R
AL Sayed M
Al-Habib A
Al-Habsi R
Al-Ishaq Z
Al-Khayal K
Al-Masri M
Al-Mohammad A
Al-mukhtar A
Al-Najjar H
Al-omishy H
Al-Sarireh B
Al-Tamimi Y
Alaa S
AlAamer O
Aladeojebi A
Alakaloko F
Alam F
Alam N
Alam R
Alameer E
Alamri A
Alamri A
Alanbuki A
Alatar A
Alawneh F
Alazawi D
Albertsmeier M
Albertsmeiers M
Albi Martin B
Alburakan A
Alcaide Matas F
Alconchel F
Aldayri Z
Aldecoa Ansorregui I
Alderson D
Aldokali N
Aleksic L
Alemanno G
Alexoudi V
Alfaro-Goldaracena A
Alfieri S
Alga A
Alghamdi M
Alhalal H
Alhamed A
Alharthi M
Alharthi R
Alhassan B
Alhassan N
Alhefdhi A
Ali AK
Ali M
Ali MF
Ali S
Aliyeva Z
Aljanadi F
Aljiffry M
Alkadeeki GZ
Alkarak S
Allemand C
Allison J
Almalik O
Almasri M
Almeciga A
Almeida A
Almeida AC
Almeida JI
Almgla N
Almond M
Almond M
Alnumani T
Alobeed O
Alomair A
Alonso de la Fuente N
Alonso Poza A
Alonso-Lamberti L
Alotaibi N
Alqannas M
Alresaini F
Alriyees L
Alsaif A
Alsaif F
Alsalamah R
Alsaraireh O
Alselaim N
Alser O
Alshaar M
Alshahrani M
Alshammari S
Alshareea E
Alsharif F
Alshaygy I
Alshryda S
Alsobhi S
Althobaiti W
Altintoprak F
Alurralde C
Alvarez E
Alvarez MR
Alyami M
Alzamanan M
Amaral MJ
Ameerally P
Amira G
Amonkar S
Amorim E
Ampollini L
Amrani L
Anania G
Anastasi A
Anchuelo Latorre J
Andaleeb U
Andaya V
Andrade AK
Andrade R
Andrijasevic S
Aneke IA
Ang K
Angele M
Angelo M
Angelou D
Angelou K
Annamalai S
Annessi V
Ansarin M
Anthoulakis C
Antic A
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Antonakis P
Antoniades K
Antonopoulou MI
Anula R
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Aragon Achig EJ
Aremu I
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Aresu G
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Athanasakis E
Athanasiou A
Athayde Nemesio R
Atherton R
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Balasubramaniam D
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Baloyiannis I
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Bashir Y
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Bernal-Sprekelsen JC
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Bertoglio P
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Bertoli G
Bescos C
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Bettoni J
Betz CS
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Beyer K
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Bezede C
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Bhangu AA
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Bhasin S
Bhatti MI
Biala M
Bianchi MF
Bianchini M
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Bianco F
Biasini M
Biasoni D
Bichoo R
Biel JR
Bigay K
Bilgin IA
Bille A
Bin Nasser A
Bin Traiki T
Biondi A
Bisagni P
Bisset C
Bissolotti G
Blackwell L
Blake D
Blanco-Colino R
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Blas Laina JL
Blatt A
Blazer D
Blazquez Martin A
Boal M
Bobinski M
Boccalatte L
Bocchialini G
Bocciolone L
Boddaert G
Boddy A
Bodla AS
Boeck MA
Boeker C
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Bogdanovic I
Bokhari A
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Bolster-van Eenennaam M
Bolt J
Bonavina G
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Bondurri A
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Bordenave M
Borges F
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Borgonovo G
Bork U
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Brana I
Branquinho A
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Bravo Infante R
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Breen KA
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Breik O
Bretherton C
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Brian E
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Brito da Silva F
Brixton G
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Brooke-Smith M
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Budacan A
Buddingh K
Bueno Canones AD
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Cairncross L
Caja Vivancos P
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Cano A
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Canonico G
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Cantalejo Diaz M
Cao H
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Capitan-Morales L
Capizzi V
Capoglu R
Capolupo GT
Carabias A
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Castillejos-Molina RA
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Chia Z
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Chiarella V
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Chidambaram S
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Chiozza M
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Publication venue: Br J Surg
Publication date: 11/11/2020
Field of study

BACKGROUND: Surgical services are preparing to scale up in areas affected by COVID-19. This study aimed to evaluate the association between preoperative SARS-CoV-2 testing and postoperative pulmonary complications in patients undergoing elective cancer surgery. METHODS: This international cohort study included adult patients undergoing elective surgery for cancer in areas affected by SARS-CoV-2 up to 19 April 2020. Patients suspected of SARS-CoV-2 infection before operation were excluded. The primary outcome measure was postoperative pulmonary complications at 30 days after surgery. Preoperative testing strategies were adjusted for confounding using mixed-effects models. RESULTS: Of 8784 patients (432 hospitals, 53 countries), 2303 patients (26.2 per cent) underwent preoperative testing: 1458 (16.6 per cent) had a swab test, 521 (5.9 per cent) CT only, and 324 (3.7 per cent) swab and CT. Pulmonary complications occurred in 3.9 per cent, whereas SARS-CoV-2 infection was confirmed in 2.6 per cent. After risk adjustment, having at least one negative preoperative nasopharyngeal swab test (adjusted odds ratio 0.68, 95 per cent confidence interval 0.68 to 0.98; P = 0.040) was associated with a lower rate of pulmonary complications. Swab testing was beneficial before major surgery and in areas with a high 14-day SARS-CoV-2 case notification rate, but not before minor surgery or in low-risk areas. To prevent one pulmonary complication, the number needed to swab test before major or minor surgery was 18 and 48 respectively in high-risk areas, and 73 and 387 in low-risk areas. CONCLUSION: Preoperative nasopharyngeal swab testing was beneficial before major surgery and in high SARS-CoV-2 risk areas. There was no proven benefit of swab testing before minor surgery in low-risk areas

Ezid

Crossref

AIR Universita degli studi di Milano

UCL Discovery

eScholarship - University of California

Archivio istituzionale della ricerca - Alma Mater Studiorum Università di Bologna

Apollo (Cambridge)

Bern Open Repository and Information System (BORIS)

Queen Mary Research Online

White Rose Research Online

Archivio istituzionale della ricerca - Università di Palermo