295 research outputs found
Editorial
We use a linear FROG technique based on electro-optic modulation to fully characterise for the first time pulses from a 1.06 ”m FP laser diode and design a grating to provide optimum pulse compression
Aminopyrrolic synthetic receptors for monosaccharides: A class of carbohydrate-binding agents endowed with antibiotic activity versus pathogenic yeasts
Calculation of bending losses in dielectric waveguides using eigenmode expansion and perfectly matched layers
Advances in high power short pulse fiber laser systems and technology
We review recent advances in Yb fiber lasers and amplifiers for high power short pulse systems. We go on to describe associated recent developments in fiber components for use in such systems. Examples include microstructured optical fibers for pulse compression and supercontinuum generation, and advanced fiber grating technology for chirped-pulse amplifier systems
<i>Gaia</i> Data Release 1. Summary of the astrometric, photometric, and survey properties
Context. At about 1000 days after the launch of Gaia we present the first Gaia data release, Gaia DR1, consisting of astrometry and photometry for over 1 billion sources brighter than magnitude 20.7.
Aims. A summary of Gaia DR1 is presented along with illustrations of the scientific quality of the data, followed by a discussion of the limitations due to the preliminary nature of this release.
Methods. The raw data collected by Gaia during the first 14 months of the mission have been processed by the Gaia Data Processing and Analysis Consortium (DPAC) and turned into an astrometric and photometric catalogue.
Results. Gaia DR1 consists of three components: a primary astrometric data set which contains the positions, parallaxes, and mean proper motions for about 2 million of the brightest stars in common with the HIPPARCOS and Tycho-2 catalogues â a realisation of the Tycho-Gaia Astrometric Solution (TGAS) â and a secondary astrometric data set containing the positions for an additional 1.1 billion sources. The second component is the photometric data set, consisting of mean G-band magnitudes for all sources. The G-band light curves and the characteristics of âŒ3000 Cepheid and RR-Lyrae stars, observed at high cadence around the south ecliptic pole, form the third component. For the primary astrometric data set the typical uncertainty is about 0.3 mas for the positions and parallaxes, and about 1 mas yrâ1 for the proper motions. A systematic component of âŒ0.3 mas should be added to the parallax uncertainties. For the subset of âŒ94 000 HIPPARCOS stars in the primary data set, the proper motions are much more precise at about 0.06 mas yrâ1. For the secondary astrometric data set, the typical uncertainty of the positions is âŒ10 mas. The median uncertainties on the mean G-band magnitudes range from the mmag level to âŒ0.03 mag over the magnitude range 5 to 20.7.
Conclusions. Gaia DR1 is an important milestone ahead of the next Gaia data release, which will feature five-parameter astrometry for all sources. Extensive validation shows that Gaia DR1 represents a major advance in the mapping of the heavens and the availability of basic stellar data that underpin observational astrophysics. Nevertheless, the very preliminary nature of this first Gaia data release does lead to a number of important limitations to the data quality which should be carefully considered before drawing conclusions from the data
Gaia Data Release 2: All-sky classification of high-amplitude pulsating stars
Out of the 1.69 billion sources in the Gaia Data Release 2 (DR2), more than half a million are published with photometric time series that exhibit light variations during 22 months of observation. An all-sky classification of common high-amplitude pulsators (Cepheids, long-period variables, Delta Scuti / SX Phoenicis, and RR Lyrae stars) is provided for stars with brightness variations greater than 0.1 mag in the G band. A semi-supervised classification approach was employed, firstly training multi-stage Random Forest classifiers with sources of known types in the literature, followed by a preliminary classification of the Gaia data and a second training phase that included a selection of the first classification results to improve the representation of some classes, before the application of the improved classifiers to the Gaia data. Dedicated validation classifiers were used to reduce the level of contamination in the published results. A relevant fraction of objects were not yet sufficiently sampled for reliable Fourier series decomposition, so classifiers were based on features derived from statistics of photometric time series in the G, BP, and RP bands, as well as from some astrometric parameters. The published classification results include 195,780 RR Lyrae stars, 150,757 long-period variables, 8550 Cepheids, and 8882 Delta Scuti / SX Phoenicis stars. All of these results represent candidates, whose completeness and contamination are described as a function of variability type and classification reliability. Results are expressed in terms of class labels and classification scores, which are available in the vari_classifier_result table of the Gaia archive
Antiseptics and disinfectants for the treatment of bacterial vaginosis: a systematic review
Background: The study objective was to assess the available data on efficacy and tolerability of antiseptics and disinfectants in treating bacterial vaginosis (BV).
Methods: A systematic search was conducted by consulting PubMed (1966-2010), CINAHL (1982-2010), IPA (1970-2010), and the Cochrane CENTRAL databases. Clinical trials were searched for by the generic names of all antiseptics and disinfectants listed in the Anatomical Therapeutic Chemical (ATC) Classification System under the code D08A. Clinical trials were considered eligible if the efficacy of antiseptics and disinfectants in the treatment of BV was assessed in comparison to placebo or standard antibiotic treatment with metronidazole or clindamycin and if diagnosis of BV relied on standard criteria such as Amsel\u27s and Nugent\u27s criteria.
Results: A total of 262 articles were found, of which 15 reports on clinical trials were assessed. Of these, four randomised controlled trials (RCTs) were withheld from analysis. Reasons for exclusion were primarily the lack of standard criteria to diagnose BV or to assess cure, and control treatment not involving placebo or standard antibiotic treatment. Risk of bias for the included studies was assessed with the Cochrane Collaboration\u27s tool for assessing risk of bias. Three studies showed non-inferiority of chlorhexidine and polyhexamethylene biguanide compared to metronidazole or clindamycin. One RCT found that a single vaginal douche with hydrogen peroxide was slightly, though significantly less effective than a single oral dose of metronidazole.
Conclusion: The use of antiseptics and disinfectants for the treatment of BV has been poorly studied and most studies are somehow methodologically flawed. There is insufficient evidence at present to advocate the use of these agents, although some studies suggest that some antiseptics may have equal efficacy compared to clindamycin or metronidazole. Further study is warranted with special regard to the long-term efficacy and safety of antiseptics and disinfectants for vaginal use
The relative importance of dispersal limitation and habitat preference in shaping spatial distribution of saplings in a tropical moist forest: a case study along a combination of hydromorphic and canopy disturbance gradients
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