204 research outputs found
Susceptibility of clinical isolates of bacteria to cefamandole, cefoxitin and cephalothin
The in vitro susceptibility was determined of 274 isolates to cephalothin and two new antibiotics, cefamandole and cefoxitin. Cefamandole was comparable to cephalothin in preventing growth of cultures of the gram positive organisms except for penicillin-resistant Staphylococcus aureus which was more sensitive to cephalothin. Cefamandole was more active than cephalothin against all the gram negative bacteria including Haemophilus influenzae and in addition it was active against many strains of Enterobacter sp. Cefoxitin was less active than cephalothin against the gram positive organisms but it was more active against most of the gram negative bacteria. In addition. It was active against Serratia and indole positive Proteus which are uniformly resistant to cephalothin
Testing Beam-Induced Quench Levels of LHC Superconducting Magnets
In the years 2009-2013 the Large Hadron Collider (LHC) has been operated with
the top beam energies of 3.5 TeV and 4 TeV per proton (from 2012) instead of
the nominal 7 TeV. The currents in the superconducting magnets were reduced
accordingly. To date only seventeen beam-induced quenches have occurred; eight
of them during specially designed quench tests, the others during injection.
There has not been a single beam- induced quench during normal collider
operation with stored beam. The conditions, however, are expected to become
much more challenging after the long LHC shutdown. The magnets will be
operating at near nominal currents, and in the presence of high energy and high
intensity beams with a stored energy of up to 362 MJ per beam. In this paper we
summarize our efforts to understand the quench levels of LHC superconducting
magnets. We describe beam-loss events and dedicated experiments with beam, as
well as the simulation methods used to reproduce the observable signals. The
simulated energy deposition in the coils is compared to the quench levels
predicted by electro-thermal models, thus allowing to validate and improve the
models which are used to set beam-dump thresholds on beam-loss monitors for Run
2.Comment: 19 page
Nuevas estrategias de digitalización dentro del megalitismo cantábrico: modelos 3d, visitas y aproximaciones virtuales del proyecto de La Cobertoria (Salas, Asturias)
This paper reports on the main methodological aspects developed during the Cobertoria’s Project, which aims to study the architecture and the landscapes linked with the prehistoric barrows in mid-western Asturias. The two main lines of the project are focused on digging remarkable sites (Cobertoria’s dolmen), as well as in updating the Sites and Monuments Record of Salas council. Regarding excavations, the archaeological record gathered in the dolmen of the Cobertoria allowed us to do several 3D photogrammetries. Two drone flights were developed over the tumulus for taking information in the two main stages of the excavations. As a result, several 3D models of different parts of the excavated area are accesible now on the web for purposes of interpretation and research. Finally, two virtual tours and two approachings to the necropolises are already available as part of a broader analysis of the landscape.El presente texto sintetiza las novedosas metodologías de registro, así como el modo de elaboración de materiales de divulgación, puestos en marcha en el proyecto de la Cobertoria, orientado al estudio de los paisajes megalíticos del área centro-occidental asturiana. Las dos líneas de trabajo preferentes son, en la actualidad, la excavación de sitios de especial interés, como el dolmen de la Cobertoria, y la actualización del catálogo de túmulos prehistóricos de todo el concejo de Salas. Durante la primera, se reunió un registro tridimensional a través de técnicas fotogramétricas y se realizaron dos vuelos de dron sobre la estructura megalítica, en 2016 y 2019, que permitieron el montaje de varios modelos 3D que ya están disponibles en web. Además, dos aproximaciones y dos visitas (ambas virtuales) a las necrópolis de San Juan y Penausén completan el lote de materiales empleados para el análisis del paisaje arqueológico, sirviendo también de itinerarios virtuales por estos lugares
A novel observation of pubic osteomyelitis due to Streptococcus viridans after dental extraction: a case report
<p>Abstract</p> <p>Introduction</p> <p>Pubic osteomyelitis should be suspected in athletic individuals with sudden groin pain, painful restriction of hip movements and fever. It is an infrequent and confusing disorder, which is often heralded by atypical gait disturbance and diffuse pain in the pelvic girdle. The most common pathogen is <it>Staphylococcus aureus </it>but, on occasions, efforts to identify infectious agents sometimes prove negative. Pubic osteomyelitis due to <it>Streptococcus viridans </it>has not been reported previously in the literature.</p> <p>Case presentation</p> <p>We describe the case of a fit 24-year-old athlete, who had a wisdom tooth extracted 2 weeks prior to the presentation, which could have served as a port of entry and predisposed the patient to transient bacteraemia.</p> <p>Conclusion</p> <p><it>S. viridans </it>is well known for causing infective endocarditis of native damaged heart valves, but to the best of the authors' knowledge it has not been reported previously as a cause of pubic osteomyelitis. We believe that this case should alert physicians to the association between dental procedures and osteomyelitis of the pubis secondary to <it>S. viridans</it>.</p
A First Search for coincident Gravitational Waves and High Energy Neutrinos using LIGO, Virgo and ANTARES data from 2007
We present the results of the first search for gravitational wave bursts
associated with high energy neutrinos. Together, these messengers could reveal
new, hidden sources that are not observed by conventional photon astronomy,
particularly at high energy. Our search uses neutrinos detected by the
underwater neutrino telescope ANTARES in its 5 line configuration during the
period January - September 2007, which coincided with the fifth and first
science runs of LIGO and Virgo, respectively. The LIGO-Virgo data were analysed
for candidate gravitational-wave signals coincident in time and direction with
the neutrino events. No significant coincident events were observed. We place
limits on the density of joint high energy neutrino - gravitational wave
emission events in the local universe, and compare them with densities of
merger and core-collapse events.Comment: 19 pages, 8 figures, science summary page at
http://www.ligo.org/science/Publication-S5LV_ANTARES/index.php. Public access
area to figures, tables at
https://dcc.ligo.org/cgi-bin/DocDB/ShowDocument?docid=p120000
Effectiveness of rotavirus vaccination in Spain
With the aim of determining rotavirus vaccine effectiveness (RVVE) in Spain, from Oct-2008/Jun-2009, 467 consecutive children below 2 years old with acute gastroenteritis (AGE) were recruited using a pediatric research network (ReGALIP-www.regalip.org) that includes primary, emergency and hospital care settings. Of 467 enrolled children, 32.3% were rotavirus positive and 35.0% had received at least one dose of any rotavirus vaccine. RRVE to prevent any episode of rotavirus AGE was 91.5% (95% CI: 83.7%-95.6%). RVVE to prevent hospitalization by rotavirus AGE was 95.6% (85.6-98.6%). No differences in RVVE were found regarding the vaccine used. Rotavirus vaccines have showed an outstanding effectiveness in Spain
The Power Board of the KM3NeT Digital Optical Module: design, upgrade, and production
The KM3NeT Collaboration is building an underwater neutrino observatory at
the bottom of the Mediterranean Sea consisting of two neutrino telescopes, both
composed of a three-dimensional array of light detectors, known as digital
optical modules. Each digital optical module contains a set of 31 three inch
photomultiplier tubes distributed over the surface of a 0.44 m diameter
pressure-resistant glass sphere. The module includes also calibration
instruments and electronics for power, readout and data acquisition. The power
board was developed to supply power to all the elements of the digital optical
module. The design of the power board began in 2013, and several prototypes
were produced and tested. After an exhaustive validation process in various
laboratories within the KM3NeT Collaboration, a mass production batch began,
resulting in the construction of over 1200 power boards so far. These boards
were integrated in the digital optical modules that have already been produced
and deployed, 828 until October 2023. In 2017, an upgrade of the power board,
to increase reliability and efficiency, was initiated. After the validation of
a pre-production series, a production batch of 800 upgraded boards is currently
underway. This paper describes the design, architecture, upgrade, validation,
and production of the power board, including the reliability studies and tests
conducted to ensure the safe operation at the bottom of the Mediterranean Sea
throughout the observatory's lifespa
Probing invisible neutrino decay with KM3NeT-ORCA
In the era of precision measurements of the neutrino oscillation parameters,
upcoming neutrino experiments will also be sensitive to physics beyond the
Standard Model. KM3NeT/ORCA is a neutrino detector optimised for measuring
atmospheric neutrinos from a few GeV to around 100 GeV. In this paper, the
sensitivity of the KM3NeT/ORCA detector to neutrino decay has been explored. A
three-flavour neutrino oscillation scenario, where the third neutrino mass
state decays into an invisible state, e.g. a sterile neutrino, is
considered. We find that KM3NeT/ORCA would be sensitive to invisible neutrino
decays with ~ at confidence
level, assuming true normal ordering. Finally, the impact of neutrino decay on
the precision of KM3NeT/ORCA measurements for ,
and mass ordering have been studied. No significant effect of neutrino decay on
the sensitivity to these measurements has been found.Comment: 27 pages, 14 figures, bibliography updated, typos correcte
Embedded Software of the KM3NeT Central Logic Board
The KM3NeT Collaboration is building and operating two deep sea neutrino
telescopes at the bottom of the Mediterranean Sea. The telescopes consist of
latices of photomultiplier tubes housed in pressure-resistant glass spheres,
called digital optical modules and arranged in vertical detection units. The
two main scientific goals are the determination of the neutrino mass ordering
and the discovery and observation of high-energy neutrino sources in the
Universe. Neutrinos are detected via the Cherenkov light, which is induced by
charged particles originated in neutrino interactions. The photomultiplier
tubes convert the Cherenkov light into electrical signals that are acquired and
timestamped by the acquisition electronics. Each optical module houses the
acquisition electronics for collecting and timestamping the photomultiplier
signals with one nanosecond accuracy. Once finished, the two telescopes will
have installed more than six thousand optical acquisition nodes, completing one
of the more complex networks in the world in terms of operation and
synchronization. The embedded software running in the acquisition nodes has
been designed to provide a framework that will operate with different hardware
versions and functionalities. The hardware will not be accessible once in
operation, which complicates the embedded software architecture. The embedded
software provides a set of tools to facilitate remote manageability of the
deployed hardware, including safe reconfiguration of the firmware. This paper
presents the architecture and the techniques, methods and implementation of the
embedded software running in the acquisition nodes of the KM3NeT neutrino
telescopes
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