75 research outputs found
Jet energy measurement with the ATLAS detector in proton-proton collisions at root s=7 TeV
- Author
- Aad G
- Abbott B
- Abdallah J
- Abdelalim AA
- Abdesselam A
- Abdinov O
- Abi B
- Abolins M
- Abramowicz H
- Abreu H
- Acerbi E
- Acharya BS
- Adams DL
- Addy TN
- Adelman J
- Aderholz M
- Adomeit S
- Adragna P
- Adye T
- Aefsky S
- Aguilar-Saavedra JA
- Aharrouche M
- Ahlen SP
- Ahles F
- Ahmad A
- Ahsan M
- Aielli G
- Akdogana T
- Akesson TPA
- Akimoto G
- Akimov AV
- Akiyama A
- Aktas A
- Alam MA
- Alam MS
- Albert J
- Albrand S
- Aleksa M
- Aleksandrov IN
- Alessandria F
- Alexa C
- Alexander G
- Alexandre G
- Alexopoulos T
- Alhroob M
- Aliev M
- Alimonti G
- Alison J
- Aliyev M
- Allport PP
- Allwood-Spiers SE
- Almenar CC
- Almond J
- Aloisio A
- Alon R
- Alonso A
- Alviggi MG
- Amako K
- Amaral P
- Amelung C
- Ammosov VV
- Amorim A
- Amoros G
- Amram N
- Anastopoulos C
- Ancu LS
- Andari N
- Andeen T
- Anders CF
- Anders G
- Anderson KJ
- Andreazza A
- Andrei V
- Andrieux M-L
- Anduaga XS
- Angerami A
- Anghinolfi F
- Anh TV
- Anjos N
- Annovi A
- Antonaki A
- Antonelli M
- Antonov A
- Antos J
- Anulli F
- Aoun S
- Apolle R
- Arabidze G
- Aracena I
- Arai Y
- Aranda CP
- Arce ATH
- Archambault JP
- Arfaoui S
- Arguin J-F
- Arik E
- Arik M
- Armbruster AJ
- Arnaez O
- Arnault C
- Artamonov A
- Artoni G
- Arutinov D
- Asai S
- Asfandiyarov R
- Ask S
- Asman B
- Asner D
- Asquith L
- Assamagan K
- Astbury A
- Astvatsatourov A
- Atoian G
- Aubert B
- Auge E
- Augsten K
- Aurousseau M
- Austin N
- Avolio G
- Avramidou R
- Axen D
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- Azuelos G
- Azuma Y
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- Baccaglioni G
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- Bach AM
- Bachacou H
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- Backhaus M
- Badescu E
- Bagnaia P
- Bahinipati S
- Bai Y
- Bailey DC
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- Baker MD
- Baker OK
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- Buckingham RM
- Buckley AG
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- Budagov IA
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- Bueso XP
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- Buira-Clark D
- Bulekov O
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- Chapman JD
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- Charlton DG
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- Cheatham S
- Chekanov S
- Chekulaev SV
- Chelkov GA
- Chelstowska MA
- Chen C
- Chen H
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- Chen X
- Cheng S
- Cheong ALF
- Cheplakov A
- Chepurnov VF
- Chernyatin V
- Cheu E
- Cheung SL
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- Chiefari G
- Chikovani L
- Childers JT
- Chilingarov A
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- Chizhov MV
- Choudalakis G
- Chouridou S
- Christidi IA
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- Damazio DO
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- De la Taille C
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- Degenhardt J
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- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/03/2013
- Field of study
The jet energy scale and its systematic uncertainty are determined for jets measured with the ATLAS detector at the LHC in proton-proton collision data at a centre-of-mass energy of √s = 7TeV corresponding to an integrated luminosity of 38 pb-1. Jets are reconstructed with the anti-kt algorithm with distance parameters R=0. 4 or R=0. 6. Jet energy and angle corrections are determined from Monte Carlo simulations to calibrate jets with transverse momenta pT≥20 GeV and pseudorapidities {pipe}η{pipe}<4. 5. The jet energy systematic uncertainty is estimated using the single isolated hadron response measured in situ and in test-beams, exploiting the transverse momentum balance between central and forward jets in events with dijet topologies and studying systematic variations in Monte Carlo simulations. The jet energy uncertainty is less than 2. 5 % in the central calorimeter region ({pipe}η{pipe}<0. 8) for jets with 60≤pT<800 GeV, and is maximally 14 % for pT<30 GeV in the most forward region 3. 2≤{pipe}η{pipe}<4. 5. The jet energy is validated for jet transverse momenta up to 1 TeV to the level of a few percent using several in situ techniques by comparing a well-known reference such as the recoiling photon pT, the sum of the transverse momenta of tracks associated to the jet, or a system of low-pT jets recoiling against a high-pT jet. More sophisticated jet calibration schemes are presented based on calorimeter cell energy density weighting or hadronic properties of jets, aiming for an improved jet energy resolution and a reduced flavour dependence of the jet response. The systematic uncertainty of the jet energy determined from a combination of in situ techniques is consistent with the one derived from single hadron response measurements over a wide kinematic range. The nominal corrections and uncertainties are derived for isolated jets in an inclusive sample of high-pT jets. Special cases such as event topologies with close-by jets, or selections of samples with an enhanced content of jets originating from light quarks, heavy quarks or gluons are also discussed and the corresponding uncertainties are determined. © 2013 CERN for the benefit of the ATLAS collaboration
Measurement of the inclusive and dijet cross-sections of b-jets in pp collisions at sqrt(s) = 7 TeV with the ATLAS detector
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- Willocq S
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- Wilson JA
- Wilson MG
- Wingerter-Seez I
- Winkelmann S
- Winklmeier F
- Wittgen M
- Wolter MW
- Wolters H
- Wooden G
- Wosiek BK
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- Woudstra MJ
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- Yamazaki T
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- Yao W-M
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- Yilmaz M
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- Zhan Z
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- Zhao L
- Zhao T
- Zhao Z
- Zhemchugov A
- Zheng S
- Zhong J
- Zhou B
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- Zhu CG
- Zhu H
- Zhu Y
- Zhuang X
- Zhuravlov V
- Zieminska D
- Zilka B
- Zimmermann R
- Zimmermann S
- Zimmermann S
- Ziolkowski M
- Zitoun R
- Zivkovic L
- Zmouchko VV
- Zobernig G
- Zoccoli A
- Zolnierowski Y
- Zsenei A
- zur Nedden M
- Zutshi V
- Zwalinski L
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 31/12/2010
- Field of study
The inclusive and dijet production cross-sections have been measured for jets
containing b-hadrons (b-jets) in proton-proton collisions at a centre-of-mass
energy of sqrt(s) = 7 TeV, using the ATLAS detector at the LHC. The
measurements use data corresponding to an integrated luminosity of 34 pb^-1.
The b-jets are identified using either a lifetime-based method, where secondary
decay vertices of b-hadrons in jets are reconstructed using information from
the tracking detectors, or a muon-based method where the presence of a muon is
used to identify semileptonic decays of b-hadrons inside jets. The inclusive
b-jet cross-section is measured as a function of transverse momentum in the
range 20 < pT < 400 GeV and rapidity in the range |y| < 2.1. The bbbar-dijet
cross-section is measured as a function of the dijet invariant mass in the
range 110 < m_jj < 760 GeV, the azimuthal angle difference between the two jets
and the angular variable chi in two dijet mass regions. The results are
compared with next-to-leading-order QCD predictions. Good agreement is observed
between the measured cross-sections and the predictions obtained using POWHEG +
Pythia. MC@NLO + Herwig shows good agreement with the measured bbbar-dijet
cross-section. However, it does not reproduce the measured inclusive
cross-section well, particularly for central b-jets with large transverse
momenta.Comment: 10 pages plus author list (21 pages total), 8 figures, 1 table, final
version published in European Physical Journal
Targeting the Wolbachia Cell Division Protein FtsZ as a New Approach for Antifilarial Therapy
- Author
- A Hoerauf
- A Hoerauf
- A Hoerauf
- A Robin
- AG Holman
- Amanda L. Garner
- B Geissler
- B Lara
- C Bandi
- C Lu
- Christian Gloeckner
- Clotilde K. Carlow
- D Dasgupta
- DH Tsao
- DJ Haydon
- DJ Scheffers
- DN Margalit
- DS Weiss
- DX Kong
- E Bi
- E Lacey
- E Nogales
- EF Bi
- EJ Gentry
- G Tegos
- GW Lubega
- HF McGarry
- HH Yu
- IA Anca
- J Foster
- J Lowe
- J Stricker
- J Wang
- JD Turner
- JM Andreu
- JM Boberek
- JM Foster
- K Dai
- KH Downing
- Kim D. Janda
- KL Johnston
- L Baldo
- LD Jennings
- MJ Taylor
- MJ Taylor
- MJ Taylor
- N Rastogi
- P Domadia
- PL Graumann
- PN Domadia
- Q Huang
- R Carballido-Lopez
- R Jaiswal
- R Rao
- RA Slayden
- RK Prichard
- RL Lock
- RO McCracken
- RU Rao
- S Bennuru
- S Kumar
- S Mand
- Sara Lustigman
- SD Redick
- SG Addinall
- SG Addinall
- SJ Arends
- SL O'Neill
- T Lappchen
- T Lappchen
- TK Beuria
- TK Beuria
- W Margolin
- W Margolin
- W Vollmer
- W Vollmer
- WD Donachie
- WJ Kozek
- Y Wang
- Y Xu
- Y Xu
- Zhiru Li
- Publication venue
- Public Library of Science
- Publication date
- 01/01/2011
- Field of study
Filarial nematode parasites are responsible for a number of devastating diseases in humans and animals. These include lymphatic filariasis and onchocerciasis that afflict 150 million people in the tropics and threaten the health of over one billion. The parasites possess intracellular bacteria, Wolbachia, which are needed for worm survival. Clearance of these bacteria with certain antibiotics leads to parasite death. These findings have pioneered the approach of using antibiotics to treat and control filarial infections. In the present study, we have investigated the cell division process in Wolbachia for new drug target discovery. We have identified the essential cell division protein FtsZ, which has a GTPase activity, as an attractive Wolbachia drug target. We describe the molecular characterization and catalytic properties of the enzyme and demonstrate that the GTPase activity is inhibited by the natural product, berberine, and small molecule inhibitors identified from a high-throughput screen. We also found that berberine was effective in reducing motility and reproduction in B. malayi parasites in vitro. Our results should facilitate the discovery of selective inhibitors of FtsZ as a novel antibiotic approach for controlling filarial infection
Measurement of the cross-section for b-jets produced in association with a Z boson at root s=7 TeV with the ATLAS detector ATLAS Collaboration
- Author
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- Wiedenmann W
- Wielers M
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- Wiglesworth C
- Wiik LAM
- Wijeratne PA
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- Wilhelm I
- Wilkens HG
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- Wilson A
- Wilson JA
- Wilson MG
- Wingerter-Seez I
- Winkelmann S
- Winklmeier F
- Wittgen M
- Wolter MW
- Wolters H
- Wong WC
- Wooden G
- Wosiek BK
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- Woudstra MJ
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- Yamaguchi H
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- Yamanaka T
- Yamaoka J
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- Yang Y
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- Yanush S
- Yao Y
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- Yildizb HD
- Yilmaz M
- Yoosoofmiya R
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- Youssef S
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- Yurkewicz A
- Zaets VG
- Zaidan R
- Zaitsev AM
- Zajacova Z
- Zalite YK
- Zanello L
- Zarzhitsky P
- Zaytsev A
- Zeitnitz C
- Zeller M
- Zeman M
- Zemla A
- Zendler C
- Zenin O
- Zenis T
- Zenonos Z
- Zenz S
- Zerwas D
- Zhan Z
- Zhang D
- Zhang H
- Zhang J
- Zhang X
- Zhang Z
- Zhao L
- Zhao T
- Zhao Z
- Zhemchugov A
- Zheng S
- Zhong J
- Zhou B
- Zhou N
- Zhou Y
- Zhu CG
- Zhu H
- Zhu J
- Zhu Y
- Zhuang X
- Zhuravlov V
- Zieminska D
- Zimmermann R
- Zimmermann S
- Zimmermann S
- Ziolkowski M
- Zitoun R
- Zivkovic L
- Zmouchko VV
- Zobernig G
- Zoccoli A
- Zolnierowski Y
- Zsenei A
- zur Nedden M
- Zutshi V
- Zwalinski L
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2011
- Field of study
A measurement is presented of the inclusive cross-section for b-jet production in association with a Z boson in pp collisions at a centre-of-mass energy of root s = 7 TeV. The analysis uses the data sample collected by the ATLAS experiment in 2010, corresponding to an integrated luminosity of approximately 36 pb(-1). The event selection requires a Z boson decaying into high P-T electrons or muons, and at least one b-jet, identified by its displaced vertex, with transverse momentum p(T) > 25 GeV and rapidity vertical bar y vertical bar < 2.1. After subtraction of background processes, the yield is extracted from the vertex mass distribution of the candidate b-jets. The ratio of this cross-section to the inclusive Z cross-section (the average number of b-jets per Z event) is also measured. Both results are found to be in good agreement with perturbative QCD predictions at next-to-leading order
Platinum-group and other traffic-related heavy metal contamination in road sediment, Guangzhou, China
- Author
- A Christoforidis
- B Gómez
- B Weiss
- C Pratt
- C Reimann
- CF Conrad
- CPR Morcelli
- CSC Wong
- CSL Lee
- D Hafeman
- DG Pearson
- E Apeagyei
- E Miguel de
- F Zereini
- FMZ Zotin
- GA Wasserman
- HF Kaiser
- HM Prichard
- HS Gandhi
- I Salma
- IM Farnham
- J Li
- J Zheng
- JH García
- JH Li
- Jie Li
- K Leopold
- K Shinotsuka
- K Simitchiev
- KG Taylor
- L Hernandez
- LID Silva da
- Lifeng Zhong
- MA Palacios
- MAS Baldanza
- NS Duzgoren-Aydin
- NS Duzgoren-Aydin
- NS Duzgoren-Aydin
- P Buat-Menard
- PN Owens
- QH Chi
- QT Liu
- R Gieré
- RA Sutherland
- RA Sutherland
- RA Sutherland
- RJ Hares
- S Artelt
- SS Park
- TB Councell
- TTT Duong
- UM Joshi
- W Birmili
- Weixia Huang
- Wen Yan
- Xianglin Tu
- Xiaohua Zhang
- XW Lu
- Y Qiu
- YM Han
- ZE Gagnon
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Enhanced inhibition of clonogenic survival of human medulloblastoma cells by multimodal treatment with ionizing irradiation, epigenetic modifiers, and differentiation-inducing drugs
- Author
- A Atmaca
- A Kakarougkas
- A Kluge
- A Masoudi
- A Petitjean
- AM Adesina
- Annegret Glasow
- AR Karpf
- B Brodska
- BH Gahwiler
- BR Han
- C Blattmann
- C Di
- CE Eyler
- CH Rickert
- CI BLISS
- D Hanahan
- DY Shin
- E Scott
- F Bruzzese
- Franziska Menzel
- G Simsek
- GR Borst
- H Wang
- HR Park
- I Muqbil
- I Patties
- I Patties
- Ina Patties
- JK Christman
- JM Bont de
- JM Encinas
- JO Palmer
- JW Shay
- K Al-Romaih
- K Camphausen
- K Gumireddy
- K Harada
- K Robertson
- KK Wong
- LJ Yu
- M Akiyama
- M Al-Hajj
- M Andres-Mach
- M Asensi
- M Badiali
- M Karahoca
- M Nakamura
- M Thiemann
- MJ Peart
- MN Prichard
- MY Chen
- N Detich
- N Zhukova
- NC Whitlock
- NG Denissova
- P Gibson
- P Lefebvre
- P Neri
- P Zhang
- PC Burger
- PN Kongkham
- Q Chang
- Q Wang
- R Bai
- RL Saylors III
- Rolf-Dieter Kortmann
- S Berendsen
- S Fattet
- S Gu
- S Venturelli
- S Weller
- SH De
- SK Singh
- SS Palii
- SS Ramalingam
- SS Ramalingam
- T Yamamori
- TM Pawlik
- U Lendahl
- U Subbiah
- U Tabori
- W Wang
- XN Li
- Y Li
- Y Yang
- YS Fu
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
The Academic Achievement of Black Students in Desegregated Schools: A Critical Review
- Author
- Armor DJ
- Armor DJ
- Beers JS
- Campbell DT
- Cohen DK
- Coleman JS
- Denmark FL
- Evans CL
- Evans CL
- Felice LG
- Frary RB
- Gifford W. Bradley
- Greenwood E
- Hansen CF
- Hanushek E
- Katz I
- Laurence A. Bradley
- Mahan AM
- Mayer RR
- Maynor W
- McClelland DC
- McPartland J
- Mosteller F
- Mosteller F
- Nunnally JC
- Pettigrew TF
- Prichard PN
- Prichard PN
- Samuels JM
- Smith MS
- St John NH
- Weinberg M
- Wilson A
- Publication venue
- 'American Educational Research Association (AERA)'
- Publication date
- Field of study
The effect of three-monthly albendazole treatment on malarial parasitemia and allergy: a household-based cluster-randomized, double-blind, placebo-controlled trial
- Author
- AA Adegnika
- Adrian J. F. Luty
- AE Wiria
- Anton J. M. de Craen
- Aprilianto E. Wiria
- Bertrand Lell
- C Flohr
- C Flohr
- DC Taylor-Robinson
- EL Webb
- Erliyani Sartono
- F Hamid
- Firdaus Hamid
- Gary T. Brice
- H Alderman
- H Mpairwe
- Heri Wibowo
- Inge Sutanto
- IR Elyazar
- Iwan Ariawan
- J Bethony
- J Feary
- J Keiser
- J Utzinger
- Jaco J. Verweij
- JE Allen
- Jeanine J. Houwing-Duistermaat
- JF Bach
- L Brutus
- Linda J. Wammes
- Linda May
- Lisette van Lieshout
- M Nacher
- Margaretta A. Prasetyani
- Maria M. M. Kaisar
- Maria Yazdanbakhsh
- NM Laird
- P Endara
- P Kirwan
- PJ Cooper
- PN Harijanto
- R Dickson
- RK Prichard
- RM Maizels
- Robert Sauerwein
- Ronald van Ree
- Roula Tsonaka
- S Lau
- S Lustigman
- S Specht
- Sitti Wahyuni
- SJ Szefler
- Steffen Borrmann
- Taniawati Supali
- Y Djuardi
- Yenny Djuardi
- Publication venue
- 'Public Library of Science (PLoS)'
- Publication date
- 01/01/2013
- Field of study
Contains fulltext :
117784.pdf (publisher's version ) (Open Access)BACKGROUND: Helminth infections are proposed to have immunomodulatory activities affecting health outcomes either detrimentally or beneficially. We evaluated the effects of albendazole treatment, every three months for 21 months, on STH, malarial parasitemia and allergy. METHODS AND FINDINGS: A household-based cluster-randomized, double-blind, placebo-controlled trial was conducted in an area in Indonesia endemic for STH. Using computer-aided block randomization, 481 households (2022 subjects) and 473 households (1982 subjects) were assigned to receive placebo and albendazole, respectively, every three months. The treatment code was concealed from trial investigators and participants. Malarial parasitemia and malaria-like symptoms were assessed in participants older than four years of age while skin prick test (SPT) to allergens as well as reported symptoms of allergy in children aged 5-15 years. The general impact of treatment on STH prevalence and body mass index (BMI) was evaluated. Primary outcomes were prevalence of malarial parasitemia and SPT to any allergen. Analysis was by intention to treat. At 9 and 21 months post-treatment 80.8% and 80.1% of the study subjects were retained, respectively. The intensive treatment regiment resulted in a reduction in the prevalence of STH by 48% in albendazole and 9% in placebo group. Albendazole treatment led to a transient increase in malarial parasitemia at 6 months post treatment (OR 4.16(1.35-12.80)) and no statistically significant increase in SPT reactivity (OR 1.18(0.74-1.86) at 9 months or 1.37 (0.93-2.01) 21 months). No effect of anthelminthic treatment was found on BMI, reported malaria-like- and allergy symptoms. No adverse effects were reported. CONCLUSIONS: The study indicates that intensive community treatment of 3 monthly albendazole administration for 21 months over two years leads to a reduction in STH. This degree of reduction appears safe without any increased risk of malaria or allergies. TRIAL REGISTRATION: Controlled-Trials.com ISRCTN83830814
Determination and Human Health Risk Assessment of Heavy Metals in Floodbasin Soils in Owerri, Southeastern Nigeria
- Author
- AW Verla
- AW Verla
- AW Verla
- B Hu
- BO Isiuku
- BO Isiuku
- C Bartrem
- C Kamunda
- CE Enyoh
- CK Lele
- DN Osujieke
- DS Kacholi
- E Prichard
- EA Asare
- EE Christian
- EFSA
- EN Verla
- EN Verla
- EN Verla
- EN Verla
- FC Ibe
- FC Ibe
- FC Ibe
- GA Engwa
- GD Christian
- HR Gebeyehu
- JR Gay
- M Tan
- MR Motsara
- National Environmental Protection Agency of China (NEPAC)
- PN Duru
- PNC Olemeforo
- R Xiao
- RDA
- S Wilbur
- SA Osakwe
- SS Alfaia
- SY Nurul
- UK Okoro
- USEPA
- USEPA
- USEPA
- USEPA
- USEPA
- VC Eze
- W Addis
- Y Liang
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Blood and lymphoreticular disorders
- Author
- Arowojolu MO
- Awbrey JJ
- Baer PN
- Barrett PA
- Clark RA
- Clark RA
- Cohen DW
- Crawford J
- Curtis A
- Deasy M
- Deasy MJ
- Dreizen S
- Dyke TE
- Eklund CM
- Genco RJ
- Glanzmann E
- Gorlin RJ
- Hamilton RE
- Kalkwarf KL
- Kantarci A
- Kinane DF
- Kirstila V
- Kyle RA
- Lavine WS
- Levine S
- Long LM
- Lynch MA
- Mealey BL
- Mintz U
- Page RC
- Page RC
- Peltier JR
- Petit JC
- Presant CA
- Prichard JF
- Renshaw HW
- Smith JF
- Spencer P
- Stafford R
- Sydney SB
- Temple T
- Thomas ED
- Waldrop TC
- Wolf JE
- Zucker-Franklin D
- Publication venue
- 'Wiley'
- Publication date
- Field of study
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