12 research outputs found

    French Roadmap for complex Systems 2008-2009

    Get PDF
    This second issue of the French Complex Systems Roadmap is the outcome of the Entretiens de Cargese 2008, an interdisciplinary brainstorming session organized over one week in 2008, jointly by RNSC, ISC-PIF and IXXI. It capitalizes on the first roadmap and gathers contributions of more than 70 scientists from major French institutions. The aim of this roadmap is to foster the coordination of the complex systems community on focused topics and questions, as well as to present contributions and challenges in the complex systems sciences and complexity science to the public, political and industrial spheres

    Finishing the euchromatic sequence of the human genome

    Get PDF
    The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead

    Barriere de potentiel aux joints de grains dans une ceramique conductrice : cas du titanate de strontium

    No full text
    SIGLECNRS T Bordereau / INIST-CNRS - Institut de l'Information Scientifique et TechniqueFRFranc

    Paracapsulapagurus poponguinensis, a new hermit crab (Decapoda, Anomura, Paguroidea) from the Maastrichtian of Senegal

    No full text
    Based on a single right cheliped from the Cape de Naze Formation (middle-upper Maastrichtian), Senegal, a new genus and species of hermit crab with capsulated setae is described. Paracapsulapagurus poponguinensis n. gen. n. sp. is characterized by platy, scale-like, non-spinose tubercles with setae arranged in curved rows. This is only the third record of a fossil hermit crab with capsulated setae. These are documented in detail using SEM-imaging. For the first time, capsulated setae are also figured for the Early Jurassic hermit crab Schobertella

    Oncogenic role and therapeutic target of leptin signaling in breast cancer and cancer stem cells

    No full text
    corecore