Acute onset of renal colic from bilateral ureterolithiasis: a case report

We report a case of a 32-year-old man, who presented to the emergency department with severe abdominal pain, with radiation to his back. An ultrasound examination revealed mild hydronephrosis bilaterally. A non-enhanced computer tomography was then performed and showed a 9 mm hyperdense image in the left ureter topography along together with an 8-mm hyperdense image in the right ureter topography, allowing us to establish the diagnosis of bilateral ureterolithiasis. The patient was taken to the operating room in order to perform ureteroscopy for endoscopic removal of the stones

Aplicação de Séries Temporais para Previsão de Despesas de Energia Elétrica do Tribunal Regional Eleitoral do Rio Grande do Norte / Time Series Application for Forecasting Electricity Expenses at the Rio Grande do Norte Regional Electoral Court

Prever antecipadamente despesas possibilita que as instituições consigam alocar recursos em ações e projetos de forma mais planejada, reduzam o trabalho operacional para realocação de recursos não utilizados e reservados para pagamento de despesas que tiveram valor maior ou menor do que o originalmente reservado, possam planejar melhor as contratações pois conseguem definir de forma antecipada como os recursos serão alocados, além de priorizar demandas com maior qualidade, uma vez que os recursos serão alocados antecipadamente e o planejamento não será feito no momento que sobra os recursos decorrentes de subutilização. O objetivo desse trabalho foi analisar, através de uma aplicação prática, o uso dos algoritmos de séries temporais como ferramenta para previsão de despesas de energia elétrica para auxiliar os gestores na elaboração do orçamento e no acompanhamento da execução orçamentária. Por fim, são demonstrados os resultados práticos entre as previsões com e sem a aplicação do algoritmo de séries temporais

BIODEGRADABILITY STARCH-BASED FILMS FROM DIFFERENT SOURCES:

A biodegradabilidade determina por quanto tempo o filme pode ser totalmente degradado no ambiente. No entanto, as metodologias atuais demandam tempo e alto custo e ignoram a interferência do solo. Portanto, este trabalho teve como objetivo avaliar o efeito dos fatores edáfico e amido em filmes elaborados e a introdução da análise de imagem como ferramenta para medir a biodegradabilidade de filmes. Amidos de raízes de parreira-do-mato, fruta-lobo, rizomas de lírio-do-brejo, mandioca, milho, inhame e glicerol foram utilizados para preparar filmes de amido por meio da técnica de casting. A partir dos filmes foi determinada sua solubilidade e biodegradação. Os testes de biodegradação foram realizados aleatoriamente, em esquema fatorial 6 x 5, em triplicata. Os fatores foram o tipo de amido utilizado para preparar os filmes e o tipo de solo utilizado para o processo de biodegradação. Os filmes de fécula de inhame e mandioca foram os mais suscetíveis à biodegradabilidade, enquanto os filmes de amido de lírio-do-brejo e parreira-do-mato apresentaram melhor desempenho, resistindo ao processo de biodegradação por mais tempo. O solo de textura franca foi o ambiente mais favorável para a ocorrência de biodegradabilidade. Diante deste estudo, verificou-se que a área degradada foi um bom indicador de biodegradabilidade e os atributos do solo juntamente com o tipo de amido mostraram uma clara interferência na evolução da biodegradação dos filmes de amido.Palavras-chaves: Filmes biodegradáveis; Propriedades do solo; Análise de imagem.Biodegradability determines how long the film can be fully degraded in the environment. However, current methodologies require time and high cost and ignore the interference of the soil. Therefore, this work aimed to evaluate the effect of the edaphic and starch factors on elaborated films, and the introduction of image analysis as a tool to measure the biodegradability of films. Starches from parreira-do-mato roots, wolf-fruit, butterfly lily rhizomes, cassava, corn, yam, and glycerol were used to prepare starch films by means of the casting technique. From the films were determined their solubility and biodegradation. The biodegradation tests were carried out at random, in a 6 x 5 factorial scheme, in triplicate. The factors being the type of starch used to prepare the films and the type of soil used for the biodegradation process. The yam and cassava starch films were the ones that were more susceptible to biodegradability, while the butterfly lily and parreira-do-mato starch films showed better performance, resisting the biodegradation process for a longer time. Loose textured soil was the most favorable environment for the occurrence of biodegradability. In view of this study, it was verified that the degraded area was a good indicator of biodegradability and the attributes of the soil together with the type of starch showed a clear interference in the evolution of biodegradation of the starch films. Keywords: Biodegradable films; Soil properties; Image analysis

Perfil epidemiológico das pacientes em unidade saúde da família em Goiânia (Goiás, Brasil)

Objective: Describe the epidemiological clinical profile of women undergoing pap smear assisted in Health School Unit Family in Goiânia, Goiás. This is an epidemiological cross-sectional study, descriptive, using data from the "Women Monitoring Registry Books in Control of Cervical Cancer" of the six teams of Unity Village Family Health School Effort of the city of Goiania, Goiás, in the period from January 1 to December 31, 2013. Of the 765 women who make up this study were aged between 15-84 years with a mean of 40.84 ± 14.85 years. Of these 34.90% were white, 51.90% had primary school education, 1.05% were pregnant women, 98.04% had no intrauterine device, 97.25% did not use hormone replacement and 80.13% said no make use of contraceptivo. Found a frequency of 86.80% of benign cellular changes, 2.09% of cervical intraepithelial neoplasia (CIN) grade I and 1.44% of CIN II and III. The most adopted approach was following routine cytological screening and treatment if necessary. The epidemiological profile is composed of white young adult women up to 40 years of low education, non-pregnant and non-use of contraception.Objetivo: Describir el perfil clínico epidemiológico de las mujeres que se someten a la prueba de Papanicolaou asistido en la Unidad Familiar de la Escuela de Salud de Goiânia, Goiás. Se trata de un estudio epidemiológico transversal, descriptivo, a partir de los datos de los Livros de Registro de Acompanhamento de Mulheres no Controle do Câncer do Colo do Útero de los seis equipos de la Unidade Escola Saúde da Família Vila Mutirão de la ciudad de Goiania, Goiás, en el período comprendido entre el 1 de enero y el 31 de diciembre de 2013. Las 765 mujeres que conforman este estudio tenían entre 15 y 84 años de edad, con una media de 40,84 ± 14,85 años. De estas 34.90% eran blancas, 51.90% tenían educación primaria, 1.05% eran mujeres embarazadas, 98.04% no tenían dispositivo intrauterino, 97.25% no usaban reemplazo hormonal y 80.13% dijeron que no usaban anticonceptivos. Se encontró una frecuencia de 86.80% de cambios celulares benignos, 2.09% de neoplasia intraepitelial cervical (NIC) grado I y 1.44% de NIC II y III. La conducta más adoptada fue seguir la rutina de rastreo citológico y tratamiento se necesario. El perfil epidemiológico está compuesto por mujeres jóvenes blancas adultas de hasta 40 años de bajo nivel educativo, sin embarazo y sin uso de anticonceptivos.Objetivo: Descrever o perfil clínico epidemiológico de mulheres submetidas ao exame colpocitológico assistidas em Unidade Escola de Saúde da Família em Goiânia, Goiás. Trata-se de um estudo epidemiológico de corte transversal, descritivo, utilizando dados dos “Livros de Registro de Acompanhamento de Mulheres no Controle do Câncer do Colo do Útero” das seis equipes da UESF da Vila Mutirão do município de Goiânia, Goiás, no período entre 1º de janeiro a 31 de dezembro de 2013. Das 765 mulheres que compõe este estudo, a idade variou de 15 a 84 anos, com média de 40,84 ± 14,85 anos. Dessas 34,90% eram brancas, 51,90% tinham primeiro grau completo, 1,05% eram gestantes, 98,04% não possuíam dispositivo intrauterino, 97,25% não faziam uso de reposição hormonal e 80,13% afirmaram não fazerem uso de contraceptivo. Foi encontrada uma frequência de 86,80% de alterações celulares benignas, 2,09% de neoplasia intraepitelial cervical (NIC) grau I e 1,44% de NIC II e III. A conduta mais adotada foi seguir rotina de rastreamento citológico e tratamento se necessário. O perfil epidemiológico é composto por mulheres jovens adultas brancas com até 40 anos de baixa escolaridade, não gestantes e sem uso de contraceptivo

Microchannel cooling for the LHCb VELO Upgrade I

The LHCb VELO Upgrade I, currently being installed for the 2022 start of LHC Run 3, uses silicon microchannel coolers with internally circulating bi-phase \cotwo for thermal control of hybrid pixel modules operating in vacuum. This is the largest scale application of this technology to date. Production of the microchannel coolers was completed in July 2019 and the assembly into cooling structures was completed in September 2021. This paper describes the R\&D path supporting the microchannel production and assembly and the motivation for the design choices. The microchannel coolers have excellent thermal peformance, low and uniform mass, no thermal expansion mismatch with the ASICs and are radiation hard. The fluidic and thermal performance is presented.Comment: 31 pages, 27 figure

A influência da transição alimentar e nutricional sobre o aumento da prevalência de doenças crônicas não transmissíveis / The influence of food and nutritional transition on the increase in the prevalence of chronic non-communicable diseases

Seguindo a tendência mundial, nas últimas décadas, o Brasil vem passando por um processo de transição demográfica, epidemiológica e nutricional, caracterizado pelo declínio da taxa de fecundidade, diminuição no ritmo do crescimento populacional, aumento da longevidade, progressiva urbanização, maior exposição a comportamento alimentar e estilo de vida inadequado além de mudanças nos padrões saúde/doença. As modificações na estrutura da dieta da população têm levado a um aumento significativo do consumo de alimentos processados e ultraprocessados, ricos em açúcares, gorduras, corantes e sódio e também na redução do consumo de alimentos naturais. A alimentação inadequada associada ao estilo de vida sedentário tem resultado em um aumento de indivíduos com excesso de peso e susceptíveis a Doenças Crônicas Não Transmissíveis (DCNTs). Diante disso, o objetivo do estudo foi identificar evidências disponíveis na literatura acerca da influência da transição alimentar e nutricional sobre o aumento da prevalência das DCNTs. Para tanto, foi realizada uma revisão narrativa com dimensão temporal entre 2000 e 2021 nos idiomas português e inglês. Os dados obtidos evidenciaram que as mudanças no padrão alimentar associadas com o sedentarismo tem repercutido em um aumento considerável da prevalência de obesidade, Diabetes Mellitus (DM), Doenças Cardiovasculares (DCVs), Hipertensão Arterial Sistêmica (HAS) e dislipidemias. Em consequência dos hábitos alimentares inadequados e estilo de vida sedentário, verifica-se a necessidade das pessoas serem orientadas quanto a uma alimentação saudável, e também estimuladas a praticarem exercício físico regularmente para ter uma melhor qualidade de vida

Role of NAFLD on the Health Related QoL Response to Lifestyle in Patients With Metabolic Syndrome: The PREDIMED Plus Cohort

ObjectiveTo evaluate the effect of Non-alcoholic fatty liver disease (NAFLD) status in the impact of lifestyle over Health-related quality of life (HRQoL) in patients with metabolic syndrome (MetS). MethodsBaseline and 1 year follow up data from the PREDIMED-plus cohort (men and women, 55-75 years old with overweight/obesity and MetS) were studied. Adherence to an energy-restricted Mediterranean Diet (er-MeDiet) and Physical Activity (PA) were assessed with a validated screeners. Hepatic steatosis index (HSI) was implemented to evaluate NAFLD while the SF-36 questionnaire provided HRQoL evaluation. Statistical analyses were performed to evaluate the influence of baseline NAFLD on HRQoL as affected by lifestyle during 1 year of follow up. ResultsData from 5205 patients with mean age of 65 years and a 48% of female participants. Adjusted linear multivariate mixed regression models showed that patients with lower probability of NAFLD (HSI < 36 points) were more responsive to er-MeDiet (beta 0.64 vs beta 0.05 per er-MeDiet adherence point, p< 0.01) and PA (beta 0.05 vs beta 0.01 per MET-h/week, p = 0.001) than those with high probability for NAFLD in terms Physical SF-36 summary in the 1 year follow up. 10 points of er-MeDiet adherence and 50 MET-h/week were thresholds for a beneficial effect of lifestyle on HRQoL physical domain in patients with lower probability of NAFLD. ConclusionThe evaluation of NAFLD by the HSI index in patients with MetS might identify subjects with different prospective sensitivity to lifestyle changes in terms of physical HRQoL (http://www.isrctn.com/ISRCTN89898870)

Antimicrobial resistance among migrants in Europe: a systematic review and meta-analysis

BACKGROUND: Rates of antimicrobial resistance (AMR) are rising globally and there is concern that increased migration is contributing to the burden of antibiotic resistance in Europe. However, the effect of migration on the burden of AMR in Europe has not yet been comprehensively examined. Therefore, we did a systematic review and meta-analysis to identify and synthesise data for AMR carriage or infection in migrants to Europe to examine differences in patterns of AMR across migrant groups and in different settings. METHODS: For this systematic review and meta-analysis, we searched MEDLINE, Embase, PubMed, and Scopus with no language restrictions from Jan 1, 2000, to Jan 18, 2017, for primary data from observational studies reporting antibacterial resistance in common bacterial pathogens among migrants to 21 European Union-15 and European Economic Area countries. To be eligible for inclusion, studies had to report data on carriage or infection with laboratory-confirmed antibiotic-resistant organisms in migrant populations. We extracted data from eligible studies and assessed quality using piloted, standardised forms. We did not examine drug resistance in tuberculosis and excluded articles solely reporting on this parameter. We also excluded articles in which migrant status was determined by ethnicity, country of birth of participants' parents, or was not defined, and articles in which data were not disaggregated by migrant status. Outcomes were carriage of or infection with antibiotic-resistant organisms. We used random-effects models to calculate the pooled prevalence of each outcome. The study protocol is registered with PROSPERO, number CRD42016043681. FINDINGS: We identified 2274 articles, of which 23 observational studies reporting on antibiotic resistance in 2319 migrants were included. The pooled prevalence of any AMR carriage or AMR infection in migrants was 25·4% (95% CI 19·1-31·8; I2 =98%), including meticillin-resistant Staphylococcus aureus (7·8%, 4·8-10·7; I2 =92%) and antibiotic-resistant Gram-negative bacteria (27·2%, 17·6-36·8; I2 =94%). The pooled prevalence of any AMR carriage or infection was higher in refugees and asylum seekers (33·0%, 18·3-47·6; I2 =98%) than in other migrant groups (6·6%, 1·8-11·3; I2 =92%). The pooled prevalence of antibiotic-resistant organisms was slightly higher in high-migrant community settings (33·1%, 11·1-55·1; I2 =96%) than in migrants in hospitals (24·3%, 16·1-32·6; I2 =98%). We did not find evidence of high rates of transmission of AMR from migrant to host populations. INTERPRETATION: Migrants are exposed to conditions favouring the emergence of drug resistance during transit and in host countries in Europe. Increased antibiotic resistance among refugees and asylum seekers and in high-migrant community settings (such as refugee camps and detention facilities) highlights the need for improved living conditions, access to health care, and initiatives to facilitate detection of and appropriate high-quality treatment for antibiotic-resistant infections during transit and in host countries. Protocols for the prevention and control of infection and for antibiotic surveillance need to be integrated in all aspects of health care, which should be accessible for all migrant groups, and should target determinants of AMR before, during, and after migration. FUNDING: UK National Institute for Health Research Imperial Biomedical Research Centre, Imperial College Healthcare Charity, the Wellcome Trust, and UK National Institute for Health Research Health Protection Research Unit in Healthcare-associated Infections and Antimictobial Resistance at Imperial College London

Pervasive gaps in Amazonian ecological research

Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear un derstanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5–7 vast areas of the tropics remain understudied.8–11 In the American tropics, Amazonia stands out as the world’s most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepre sented in biodiversity databases.13–15 To worsen this situation, human-induced modifications16,17 may elim inate pieces of the Amazon’s biodiversity puzzle before we can use them to understand how ecological com munities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple or ganism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region’s vulnerability to environmental change. 15%–18% of the most ne glected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lostinfo:eu-repo/semantics/publishedVersio