Minimally invasive esophageal surgery-standard of care-our experience

Background: Surgery is the most effective treatment for the resectable esophageal cancer of the middle & lower third and gastro-esophageal junction (GEJ) tumors. We hereby scrutinise our experience in minimally invasive esophageal surgery (MIES) to evaluate its safety and efficacy as an oncosurgical procedure.Methods: The study included99consecutive patients. Depending on the location of the tumor, either thoracoscopic transthoracic esophagectomy (TTE) in prone position or laparoscopic transhiatal esophagectomy (THE) was planned. 2 field comprehensive nodal dissection were part of both the surgical procedures.Results: 05 patients were excluded, 18 were inoperable and 12 had open surgery.64 underwent MIES (THE-37, TTE-27), Male: Female-31:33. Nodal Harvest (nodes): THE-14.27, TTE-14.77. Margins (cm): THE-proximal (P) - 6.70, distal (D) -2.51, TTE: (P)-5.41, (D)-5.11.30 days Morbidity (26): cervical leak-05, left vocal cord palsy-05, tracheostomy-03, respiratory insufficiency-03, aspiration-01, chyle leak-01, exploratory laparotomy-01, cardiac-02, stroke-01, surgical emphysema -01, abdominal wound Infection -0330 days Mortality (1) –pulmonary embolus. Operative time (minutes): THE-234, TTE-322. Blood loss (ml/patient): THE-265, TTE-380. Hospital stays (days): THE-7.3, TTE-10.Conclusions: 79% of properly selected & evaluated cases underwent MIES, with one Mortality and 26 events of morbidity.  6% required conversion. The procedure detected inoperability in 16% cases. The nodal yield, status of margins, operative time, blood loss and hospital stay indicates that MIES has a future to become a standard of care in the treatment of esophageal cancers.

Psychometric Properties and Correlates of Precarious Manhood Beliefs in 62 Nations

Precarious manhood beliefs portray manhood, relative to womanhood, as a social status that is hard to earn, easy to lose, and proven via public action. Here, we present cross-cultural data on a brief measure of precarious manhood beliefs (the Precarious Manhood Beliefs scale [PMB]) that covaries meaningfully with other cross-culturally validated gender ideologies and with country-level indices of gender equality and human development. Using data from university samples in 62 countries across 13 world regions (N = 33,417), we demonstrate: (1) the psychometric isomorphism of the PMB (i.e., its comparability in meaning and statistical properties across the individual and country levels); (2) the PMB’s distinctness from, and associations with, ambivalent sexism and ambivalence toward men; and (3) associations of the PMB with nation-level gender equality and human development. Findings are discussed in terms of their statistical and theoretical implications for understanding widely-held beliefs about the precariousness of the male gender role

Transcriptome analysis of air-breathing land slug, Incilaria fruhstorferi reveals functional insights into growth, immunity, and reproduction

Abstract Background Incilaria (= Meghimatium) fruhstorferi is an air-breathing land slug found in restricted habitats of Japan, Taiwan and selected provinces of South Korea (Jeju, Chuncheon, Busan, and Deokjeokdo). The species is on a decline due to depletion of forest cover, predation by natural enemies, and collection. To facilitate the conservation of the species, it is important to decide on a number of traits related to growth, immunity and reproduction addressing fitness advantage of the species. Results The visceral mass transcriptome of I. fruhstorferi was enabled using the Illumina HiSeq 4000 sequencing platform. According to BUSCO (Benchmarking Universal Single-Copy Orthologs) method, the transcriptome was considered complete with 91.8% of ortholog genes present (Single: 70.7%; Duplicated: 21.1%). A total of 96.79% of the raw read sequences were processed as clean reads. TransDecoder identified 197,271 contigs that contained candidate-coding regions. Of a total of 50,230 unigenes, 34,470 (68.62% of the total unigenes) annotated to homologous proteins in the Protostome database (PANM-DB). The GO term and KEGG pathway analysis indicated genes involved in metabolism, phosphatidylinositol signalling system, aminobenzoate degradation, and T-cell receptor signalling pathway. Many genes associated with molluscan innate immunity were categorized under pathogen recognition receptor, TLR signalling pathway, MyD88 dependent pathway, endogenous ligands, immune effectors, antimicrobial peptides, apoptosis, and adaptation-related. The reproduction-associated unigenes showed homology to protein fem-1, spermatogenesis-associated protein, sperm associated antigen, and testis expressed sequences, among others. In addition, we identified key growth-related genes categorized under somatotrophic axis, muscle growth, chitinases and collagens. A total of 4822 Simple Sequence Repeats (SSRs) were also identified from the unigene sequences of I. fruhstorferi. Conclusions This is the first available genomic information for non-model land slug, I. fruhstorferi focusing on genes related to growth, immunity, and reproduction, with additional focus on microsatellites and repeating elements. The transcriptome provides access to greater number of traits of unknown relevance in the species that could be exploited for in-depth analyses of evolutionary plasticity and making informed choices during conservation planning. This would be appropriate for understanding the dynamics of the species on a priority basis considering the ecological, health, and social benefits

Country‐level and individual‐level predictors of men's support for gender equality in 42 countries

International audienc

Gendered Self-Views across 62 Countries: A Test of Competing Models

Social role theory posits that binary gender gaps in agency and communion should be larger in less egalitarian countries, reflecting these countries’ more pronounced sex-based power divisions. Conversely, evolutionary and self-construal theorists suggest that gender gaps in agency and communion should be larger in more egalitarian countries, reflecting the greater autonomy support and flexible self-construction processes present in these countries. Using data from 62 countries (N = 28,640), we examine binary gender gaps in agentic and communal self-views as a function of country-level objective gender equality (the Global Gender Gap Index) and subjective distributions of social power (the Power Distance Index). Findings show that in more egalitarian countries, gender gaps in agency are smaller and gender gaps in communality are larger. These patterns are driven primarily by cross-country differences in men’s self-views and by the Power Distance Index (PDI) more robustly than the Global Gender Gap Index (GGGI). We consider possible causes and implications of these findings

Gendered Self-Views Across 62 Countries: A Test of Competing Models

Social role theory posits that binary gender gaps in agency and communion should be larger in less egalitarian countries, reflecting these countries’ more pronounced sex-based power divisions. Conversely, evolutionary and self-construal theorists suggest that gender gaps in agency and communion should be larger in more egalitarian countries, reflecting the greater autonomy support and flexible self-construction processes present in these countries. Using data from 62 countries (N = 28,640), we examine binary gender gaps in agentic and communal self-views as a function of country-level objective gender equality (the Global Gender Gap Index) and subjective distributions of social power (the Power Distance Index). Findings show that in more egalitarian countries, gender gaps in agency are smaller and gender gaps in communality are larger. These patterns are driven primarily by cross-country differences in men’s self-views and by the Power Distance Index (PDI) more robustly than the Global Gender Gap Index (GGGI). We consider possible causes and implications of these findings

sj-docx-1-spp-10.1177_19485506221129687 – Supplemental material for Gendered Self-Views Across 62 Countries: A Test of Competing Models

Supplemental material, sj-docx-1-spp-10.1177_19485506221129687 for Gendered Self-Views Across 62 Countries: A Test of Competing Models by Natasza Kosakowska-Berezecka, Jennifer K. Bosson, Paweł Jurek, Tomasz Besta, Michał Olech, Joseph A. Vandello, Michael Bender, Justine Dandy, Vera Hoorens, Inga Jasinskaja-Lahti, Eric Mankowski, Satu Venäläinen, Sami Abuhamdeh, Collins Badu Agyemang, Gülçin Akbaş, Nihan Albayrak-Aydemir, Soline Ammirati, Joel Anderson, Gulnaz Anjum, Amarina Ariyanto, John Jamir Benzon R. Aruta, Mujeeba Ashraf, Aistė Bakaitytė, Maja Becker, Chiara Bertolli, Dashamir Bërxulli, Deborah L. Best, Chongzeng Bi, Katharina Block, Mandy Boehnke, Renata Bongiorno, Janine Bosak, Annalisa Casini, Qingwei Chen, Peilian Chi, Vera Cubela Adoric, Serena Daalmans, Soledad de Lemus, Sandesh Dhakal, Nikolay Dvorianchikov, Sonoko Egami, Edgardo Etchezahar, Carla Sofia Esteves, Laura Froehlich, Efrain Garcia-Sanchez, Alin Gavreliuc, Dana Gavreliuc, Ángel Gomez, Francesca Guizzo, Sylvie Graf, Hedy Greijdanus, Ani Grigoryan, Joanna Grzymała-Moszczyńska, Keltouma Guerch, Marie Gustafsson Sendén, Miriam-Linnea Hale, Hannah Hämer, Mika Hirai, Lam Hoang Duc, Martina Hřebíčková, Paul B. Hutchings, Dorthe Høj Jensen, Serdar Karabati, Kaltrina Kelmendi, Gabriella Kengyel, Narine Khachatryan, Rawan Ghazzawi, Mary Kinahan, Teri A. Kirby, Monika Kovacs, Desiree Kozlowski, Vladislav Krivoshchekov, Kuba Kryś, Clara Kulich, Tai Kurosawa, Nhan Thi Lac An, Javier Labarthe-Carrara, Mary Anne Lauri, Ioana Latu, Abiodun Musbau Lawal, Junyi Li, Jana Lindner, Anna Lindqvist, Angela T. Maitner, Elena Makarova, Ana Makashvili, Shera Malayeri, Sadia Malik, Tiziana Mancini, Claudia Manzi, Silvia Mari, Sarah E. Martiny, Claude-Hélène Mayer, Vladimir Mihić, Jasna MiloševićĐorđević, Eva Moreno-Bella, Silvia Moscatelli, Andrew Bryan Moynihan, Dominique Muller, Erita Narhetali, Félix Neto, Kimberly A. Noels, Boglárka Nyúl, Emma C. O’Connor, Danielle P. Ochoa, Sachiko Ohno, Sulaiman Olanrewaju Adebayo, Randall Osborne, Maria Giuseppina Pacilli, Jorge Palacio, Snigdha Patnaik, Vassilis Pavlopoulos, Pablo Pérez de León, Ivana Piterová, Juliana Barreiros Porto, Angelica Puzio, Joanna Pyrkosz-Pacyna, Erico Rentería Pérez, Emma Renström, Tiphaine Rousseaux, Michelle K. Ryan, Saba Safdar, Mario Sainz, Marco Salvati, Adil Samekin, Simon Schindler, A. Timur Sevincer, Masoumeh Seydi, Debra Shepherd, Sara Sherbaji, Toni Schmader, Cláudia Simão, Rosita Sobhie, Jurand Sobiecki, Lucille De Souza, Emma Sarter, Dijana Sulejmanović, Katie E. Sullivan, Mariko Tatsumi, Lucy Tavitian-Elmadjian, Suparna Jain Thakur, Quang Thi Mong Chi, Beatriz Torre, Ana Torres, Claudio V. Torres, Beril Türkoğlu, Joaquín Ungaretti, Timothy Valshtein, Colette Van Laar, Jolanda van der Noll, Vadym Vasiutynskyi, Christin-Melanie Vauclair, Neharika Vohra, Marta Walentynowicz, Colleen Ward, Anna Włodarczyk, Yaping Yang, Vincent Yzerbyt, Valeska Zanello, Antonella Ludmila Zapata-Calvente, Magdalena Zawisza, Rita Žukauskienė and Magdalena Żadkowska in Social Psychological and Personality Science</p