1,013 research outputs found

    The pediatrician and the digital clinic

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    Goal and scope in life cycle sustainability analysis: the case of hydrogen production from biomass.

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    The framework for life cycle sustainability analysis (LCSA) developed within the project CALCAS (Co-ordination Action for innovation in Life-Cycle Analysis for Sustainability) is introducing a truly integrated approach for sustainability studies. However, it needs to be further conceptually refined and to be made operational. In particular, one of the gaps still hindering the adoption of integrated analytic tools for sustainability studies is the lack of a clear link between the goal and scope definition and the modeling phase. This paper presents an approach to structure the goal and scope phase of LCSA so as to identify the relevant mechanisms to be further detailed and analyzed in the modeling phase. The approach is illustrated with an on-going study on a new technology for the production of high purity hydrogen from biomass, to be used in automotive fuel cells

    How can the European ceramic tile industry meet the EU's low-carbon targets? A life cycle perspective

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    Ceramic tile manufacturing is deemed to be an energy intensive industry, mainly based on combustion processes and, therefore, subject to European policies aiming at reducing greenhouse gas emissions. The “Roadmap for moving to a competitive low-carbon economy in 2050”, approved by the European Commission, calls for sectoral strategies to reduce CO2 emissions by 20% by 2020 and by 83–87% by 2050, compared to 1990 CO2 emissions. This study included up to 17 technological alternatives and their combination, resulting in 25 technological scenarios associated to the life cycle of porcelain stoneware tiles. In this regard, a high parametrized LCA model was developed to allow for the required flexibility. The scenario analysis can be used: a) to estimate the degree of technological innovation required; b) to define and to focus strategies and; c) to devise the lines of technological development that need to be implemented in the ceramic tile manufacturing sector in the coming years. The alternatives consisted of endogenous and exogenous sectoral technologies. The technologic alternatives involved changes in product design (thickness and decoration), changes in the manufacturing process (preparation of raw material by dry or wet route, and simultaneous implementation of thermal energy efficiency techniques), and changes in the energy sources (hybrid and/or electric driers, and kilns and decarbonization of the power grid mix). It was clearly proven that the wider the scope of the Life Cycle Assessment study is, the greater eco-innovations are necessary. In all the studied scenarios, the manufacturing stage was always the most significant from the global warming point of view. Finally, regarding the achievability of EU objectives, the results of this study show that the implementation of widespread technologies suffice for fulfilling 2020 targets; nevertheless, only some limited combinations of both widespread and ambitious breakthrough technologies may achieve the 2050 reduction targets

    Using the product environmental footprint for supply chain management : lessons learned from a case study on pork

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    Purpose: The purpose of this study was to test the chainorganization environmental footprint (chain-OEF) approach by applying it to part of a pork production chain in Belgium. The approach is supposed to provide insight into the environmental impact of a specific production chain in an efficient manner by applying pragmatic data collection throughout the chain. This is achieved by allocating the environmental impact of each of the production sites to the product of interest using straightforward allocation rules. Methods: The cradle-to-gate (up to retail) environmental impact of pork was determined by life cycle assessment (LCA), in line with the product and organisation environmental footprint guidelines (PEF and OEF; European Commission 2013b). Foreground data was gathered at a feed production site, two farmers, a slaughterhouse and a meat processing site. All foreground operations are part of the same pork production chain in Belgium. The chain was completed using background data from Ecoinvent v3.01 (Wernet et al. 2016), Agri-Footprint v1.0 (Blonk 2014), European Life Cycle Database v3.0, LCA Food Database (Nielsen et al. 2003) and OEF Sector Rules Retail (Humbert et al. 2015b). The impact was quantified using the international reference life cycle data system (ILCD) midpoint method for 14 impact categories, but focussing on climate change. Results and discussion: The total carbon footprint of the cradle-to-gate pork production system equals 0.46 kg CO2-eq. (100 g pork)−1. This result is quite similar to that of earlier studies analysing the pork production chain: 0.58 and 0.57 kg CO2-eq. (100 g pork)−1 (Bracquené et al. 2011, Agri-Footprint 2014). Most of the carbon footprint was caused by feed production and more specifically, by the feed ingredients and their transport. Grains, soy and palm oil have the largest impact contributions. The farms are responsible for most of the remaining impact. N2O and CH4 emissions are the largest cause of greenhouse gas emissions at the farms. Also, in the other 13 considered impact categories, feed production and farming are responsible for more than half of the total impact, mostly followed by meat processing. Conclusions: Applying the chain-OEF approach in this study has shown that a chain LCA can be performed successfully and pragmatic data collection allows obtaining LCA results relatively fast, especially for small or medium-sized enterprises (SMEs). Whereas data availability was not such an issue, the main bottlenecks identified are data management and the link of LCA to other disciplines such as engineering, policy, etc. which could increase the added value of LCA studies

    Is the haematopoietic effect of testosterone mediated by erythropoietin? The results of a clinical trial in older men

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    The stimulatory effects of testosterone on erythropoiesis are very well known, but the mechanisms underlying the erythropoietic action of testosterone are still poorly understood, although erythropoietin has long been considered a potential mediator. A total of 108 healthy men >65 years old with serum testosterone concentration <475 ng/dL were recruited by direct mailings to alumni of the University of Pennsylvania and Temple University, and randomized to receive a 60-cm(2) testosterone or placebo patch for 36 months. Ninety-six subjects completed the trial. We used information and stored serum specimens from this trial to test the hypothesis that increasing testosterone increases haemoglobin by stimulating erythropoietin production. We used information of 67 men, 43 in the testosterone group and 24 in the placebo group who had banked specimens available for assays of testosterone, haemoglobin and erythropoietin at baseline and after 36 months. The original randomized clinical study was primarily designed to verify the effects of testosterone on bone mineral density. The primary outcome of this report was to investigate whether or not transdermal testosterone increases haemoglobin by increasing erythropoietin levels. The mean age +/- SD of the 67 subjects at baseline was 71.8 +/- 4.9 years. Testosterone replacement therapy for 36 months, as compared with placebo, induced a significant increase in haemoglobin (0.86 +/- 0.31 g/dL, p = 0.01), but no change in erythropoietin levels (-0.24 +/- 2.16 mIU/mL, p = 0.91). Included time-varying measure of erythropoietin did not significantly account for the effect of testosterone on haemoglobin (Treatment-by-time: beta = 0.93, SE = 0.33, p = 0.01). No serious adverse effect was observed. Transdermal testosterone treatment of older men for 36 months significantly increased haemoglobin, but not erythropoietin levels. The haematopoietic effect of testosterone does not appear to be mediated by stimulation of erythropoietin production

    Azimuthal anisotropy of charged jet production in root s(NN)=2.76 TeV Pb-Pb collisions

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    We present measurements of the azimuthal dependence of charged jet production in central and semi-central root s(NN) = 2.76 TeV Pb-Pb collisions with respect to the second harmonic event plane, quantified as nu(ch)(2) (jet). Jet finding is performed employing the anti-k(T) algorithm with a resolution parameter R = 0.2 using charged tracks from the ALICE tracking system. The contribution of the azimuthal anisotropy of the underlying event is taken into account event-by-event. The remaining (statistical) region-to-region fluctuations are removed on an ensemble basis by unfolding the jet spectra for different event plane orientations independently. Significant non-zero nu(ch)(2) (jet) is observed in semi-central collisions (30-50% centrality) for 20 <p(T)(ch) (jet) <90 GeV/c. The azimuthal dependence of the charged jet production is similar to the dependence observed for jets comprising both charged and neutral fragments, and compatible with measurements of the nu(2) of single charged particles at high p(T). Good agreement between the data and predictions from JEWEL, an event generator simulating parton shower evolution in the presence of a dense QCD medium, is found in semi-central collisions. (C) 2015 CERN for the benefit of the ALICE Collaboration. Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).Peer reviewe

    Production of He-4 and (4) in Pb-Pb collisions at root(NN)-N-S=2.76 TeV at the LHC

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    Results on the production of He-4 and (4) nuclei in Pb-Pb collisions at root(NN)-N-S = 2.76 TeV in the rapidity range vertical bar y vertical bar <1, using the ALICE detector, are presented in this paper. The rapidity densities corresponding to 0-10% central events are found to be dN/dy4(He) = (0.8 +/- 0.4 (stat) +/- 0.3 (syst)) x 10(-6) and dN/dy4 = (1.1 +/- 0.4 (stat) +/- 0.2 (syst)) x 10(-6), respectively. This is in agreement with the statistical thermal model expectation assuming the same chemical freeze-out temperature (T-chem = 156 MeV) as for light hadrons. The measured ratio of (4)/He-4 is 1.4 +/- 0.8 (stat) +/- 0.5 (syst). (C) 2018 Published by Elsevier B.V.Peer reviewe

    Forward-central two-particle correlations in p-Pb collisions at root s(NN)=5.02 TeV

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    Two-particle angular correlations between trigger particles in the forward pseudorapidity range (2.5 2GeV/c. (C) 2015 CERN for the benefit of the ALICE Collaboration. Published by Elsevier B. V.Peer reviewe

    Event-shape engineering for inclusive spectra and elliptic flow in Pb-Pb collisions at root(NN)-N-S=2.76 TeV

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    Long-range angular correlations on the near and away side in p&#8211;Pb collisions at

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