794 research outputs found
Connecting RS OPh to [some] Type Ia Supernovae
Aims: Recurrent nova systems like RS Oph have been proposed as a possible
channel to Type Ia Supernova explosions, based on the high mass of the
accreting white dwarf. Additional support to this hypothesis has been recently
provided by the detection of circumstellar material around SN2006X and
SN2007le, showing a structure compatible with that expected for recurrent nova
outbursts.In this paper we investigate the circumstellar environment of RS Oph
and its structure, with the aim of establishing a firmer and independent link
between this class of objects and Type Ia SN progenitors.
Methods: We study the time evolution of CaII, NaI and KI absorption features
in RS Oph, before, during, and after the last outburst, using multi-epoch,
high-resolution spectroscopy, and applying the same method adopted for SN2006X
and SN2007le.
Results: A number of components, blue-shifted with respect to the systemic
velocity of RS Oph, are detected. In particular, one feature strongly weakens
in the first two weeks after the outburst, simultaneously with the
disappearance of very narrow P-Cyg profiles overimposed on the much wider nova
emission lines of H, He, FeII and other elements.
Conclusions: We interpret these facts as the signature of density
enhancements in the circumstellar material, suggesting that the recurrent
eruptions might indeed create complex structures within the material lost by
the donor star. This establishes a strong link between RS Oph and the
progenitor system of the Type Ia SN2006X, for which similar features have been
detected.Comment: 8 pages, 10 figures. Accepted for publication in Astronomy and
Astrophysic
Massless D-strings and moduli stabilization in type I cosmology
We consider the cosmological evolution induced by the free energy F of a gas
of maximally supersymmetric heterotic strings at finite temperature and weak
coupling in dimension D>=4. We show that F, which plays the role of an
effective potential, has minima associated to enhanced gauge symmetries, where
all internal moduli can be attracted and dynamically stabilized. Using the fact
that the heterotic/type I S-duality remains valid at finite temperature and can
be applied at each instant of a quasi-static evolution, we find in the dual
type I cosmology that all internal NS-NS and RR moduli in the closed string
sector and the Wilson lines in the open string sector can be stabilized. For
the special case of D=6, the internal volume modulus remains a flat direction,
while the dilaton is stabilized. An essential role is played by light D-string
modes wrapping the internal manifold and whose contribution to the free energy
cannot be omitted, even when the type I string is at weak coupling. As a
result, the order of magnitude of the internal radii expectation values on the
type I side is (lambda_I alpha')^{1/2}, where lambda_I is the ten-dimensional
string coupling. The non-perturbative corrections to the type I free energy can
alternatively be described as effects of "thermal E1-instantons", whose
worldsheets wrap the compact Euclidean time cycle.Comment: 39 pages, 1 figur
Development of a core outcome set for orthodontic trials using a mixed-methods approach: Protocol for a multicentre study
© 2017 The Author(s). Background: Orthodontic treatment is commonly undertaken in young people, with over 40% of children in the UK needing treatment and currently one third having treatment, at a cost to the National Health Service in England and Wales of £273 million each year. Most current research about orthodontic care does not consider what patients truly feel about, or want, from treatment, and a diverse range of outcomes is being used with little consistency between studies. This study aims to address these problems, using established methodology to develop a core outcome set for use in future clinical trials of orthodontic interventions in children and young people. Methods/design: This is a mixed-methods study incorporating four distinct stages. The first stage will include a scoping review of the scientific literature to identify primary and secondary outcome measures that have been used in previous orthodontic clinical trials. The second stage will involve qualitative interviews and focus groups with orthodontic patients aged 10 to 16 years to determine what outcomes are important to them. The outcomes elicited from these two stages will inform the third stage of the study in which a long-list of outcomes will be ranked in terms of importance using electronic Delphi surveys involving clinicians and patients. The final stage of the study will involve face-to-face consensus meetings with all stakeholders to discuss and agree on the outcome measures that should be included in the final core outcome set. Discussion: This research will help to inform patients, parents, clinicians and commissioners about outcomes that are important to young people undergoing orthodontic treatment. Adoption of the core outcome set in future clinical trials of orthodontic treatment will make it easier for results to be compared, contrasted and combined. This should translate into improved decision-making by all stakeholders involved. Trial registration: The project has been registered on the Core Outcome Measures in Effectiveness Trials (COMET) website, January 2016
Home Range Use and Movement Patterns of Non-Native Feral Goats in a Tropical Island Montane Dry Landscape
Advances in wildlife telemetry and remote sensing technology facilitate studies of broad-scale movements of ungulates in relation to phenological shifts in vegetation. In tropical island dry landscapes, home range use and movements of non-native feral goats (Capra hircus) are largely unknown, yet this information is important to help guide the conservation and restoration of some of the world’s most critically endangered ecosystems. We hypothesized that feral goats would respond to resource pulses in vegetation by traveling to areas of recent green-up. To address this hypothesis, we fitted six male and seven female feral goats with Global Positioning System (GPS) collars equipped with an Argos satellite upload link to examine goat movements in relation to the plant phenology using the Normalized Difference Vegetation Index (NDVI). Movement patterns of 50% of males and 40% of females suggested conditional movement between non-overlapping home ranges throughout the year. A shift in NDVI values corresponded with movement between primary and secondary ranges of goats that exhibited long-distance movement, suggesting that vegetation phenology as captured by NDVI is a good indicator of the habitat and movement patterns of feral goats in tropical island dry landscapes. In the context of conservation and restoration of tropical island landscapes, the results of our study identify how non-native feral goats use resources across a broad landscape to sustain their populations and facilitate invasion of native plant communities
High Speed and High Efficiency Travelling Wave Single-Photon Detectors Embedded in Nanophotonic Circuits
Ultrafast, high quantum efficiency single photon detectors are among the most
sought-after elements in modern quantum optics and quantum communication. High
photon detection efficiency is essential for scalable measurement-based quantum
computation, quantum key distribution, and loophole-free Bell experiments.
However, imperfect modal matching and finite photon absorption rates have
usually limited the maximum attainable detection efficiency of single photon
detectors. Here we demonstrate a superconducting nanowire detector atop
nanophotonic waveguides which allows us to drastically increase the absorption
length for incoming photons. When operating the detectors close to the critical
current we achieve high on-chip single photon detection efficiency up to 91% at
telecom wavelengths, with uncertainty dictated by the variation of the
waveguide photon flux. We also observe remarkably low dark count rates without
significant compromise of detection efficiency. Furthermore, our detectors are
fully embedded in a scalable silicon photonic circuit and provide ultrashort
timing jitter of 18ps. Exploiting this high temporal resolution we demonstrate
ballistic photon transport in silicon ring resonators. The direct
implementation of such a detector with high quantum efficiency, high detection
speed and low jitter time on chip overcomes a major barrier in integrated
quantum photonics
Supermassive Black Holes in Galactic Nuclei: Past, Present and Future Research
This review discusses the current status of supermassive black hole research,
as seen from a purely observational standpoint. Since the early '90s, rapid
technological advances, most notably the launch of the Hubble Space Telescope,
the commissioning of the VLBA and improvements in near-infrared speckle imaging
techniques, have not only given us incontrovertible proof of the existence of
supermassive black holes, but have unveiled fundamental connections between the
mass of the central singularity and the global properties of the host galaxy.
It is thanks to these observations that we are now, for the first time, in a
position to understand the origin, evolution and cosmic relevance of these
fascinating objects.Comment: Invited Review, 114 pages. Because of space requirements, this
version contains low resolution figures. The full resolution version can be
downloaded from http://www.physics.rutgers.edu/~lff/publications.htm
Assay for high glucose-mediated islet cell sensitization to apoptosis induced by streptozotocin and cytokines
Pancreatic β-cell apoptosis is known to participate in the β-cell destruction process that occurs in diabetes. It has been described that high glucose level induces a hyperfunctional status which could provoke apoptosis. This phenomenon is known as glucotoxicity and has been proposed that it can play a role in type 1 diabetes mellitus pathogenesis. In this study we develop an experimental design to sensitize pancreatic islet cells by high glucose to streptozotocin (STZ) and proinflammatory cytokines [interleukin (IL)-1β, tumor necrosis factor (TNF)-α and interferon (IFN)-γ]-induced apoptosis. This method is appropriate for subsequent quantification of apoptotic islet cells stained with Tdt-mediated dUTP Nick-End Labeling (TUNEL) and protein expression assays by Western Blotting (WB)
AlignNemo: A Local Network Alignment Method to Integrate Homology and Topology
Local network alignment is an important component of the analysis of protein-protein interaction networks that may lead to the identification of evolutionary related complexes. We present AlignNemo, a new algorithm that, given the networks of two organisms, uncovers subnetworks of proteins that relate in biological function and topology of interactions. The discovered conserved subnetworks have a general topology and need not to correspond to specific interaction patterns, so that they more closely fit the models of functional complexes proposed in the literature. The algorithm is able to handle sparse interaction data with an expansion process that at each step explores the local topology of the networks beyond the proteins directly interacting with the current solution. To assess the performance of AlignNemo, we ran a series of benchmarks using statistical measures as well as biological knowledge. Based on reference datasets of protein complexes, AlignNemo shows better performance than other methods in terms of both precision and recall. We show our solutions to be biologically sound using the concept of semantic similarity applied to Gene Ontology vocabularies. The binaries of AlignNemo and supplementary details about the algorithms and the experiments are available at: sourceforge.net/p/alignnemo
Measurement of χ c1 and χ c2 production with s√ = 7 TeV pp collisions at ATLAS
The prompt and non-prompt production cross-sections for the χ c1 and χ c2 charmonium states are measured in pp collisions at s√ = 7 TeV with the ATLAS detector at the LHC using 4.5 fb−1 of integrated luminosity. The χ c states are reconstructed through the radiative decay χ c → J/ψγ (with J/ψ → μ + μ −) where photons are reconstructed from γ → e + e − conversions. The production rate of the χ c2 state relative to the χ c1 state is measured for prompt and non-prompt χ c as a function of J/ψ transverse momentum. The prompt χ c cross-sections are combined with existing measurements of prompt J/ψ production to derive the fraction of prompt J/ψ produced in feed-down from χ c decays. The fractions of χ c1 and χ c2 produced in b-hadron decays are also measured
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