Seroprevalencia de la toxoplasmosis humana en Córdoba

Se realiza un estudio sobre seroprevalencia de la toxoplasmosis humana en Córdoba, mediante inmunofluorescencia indirecta y hemaglutinación indirecta. La muestra encuestada se compone de 443 sueros, 356 personas supuestamente sanas (estudiantes fundamentalmente) y 87, consideradas de “alto riesgo” (enfermos del Hospital “Reina Sofía”). La positividad obtenida para el total de la muestra ha sido del 43,79 % con IFI y 53,50 % para HAI. Con respecto al sexo, la prevalencia es superior en mujeres con un 54,36 % y 70,47 % con IFI y HAI, respectivamente, en varones el 38,43 % y 44,90 % para las mismas pruebas. En relación con la procedencia de la muestra, 31,lB % con IFI y 43,25 % para HAI sobre la población normal, en la de “alto riesgo” para ambas pruebas el 95,40 %. Entre ambas pruebas hay diferencias significativas a títulos bajos, no así en diluciones altas, Concluimos que la toxoplasmosis humana está presente y difundida en las poblaciones estudiadasA seroprevalency study of human toxoplasmosis was carried out in Córdoba, using indirect immunofluorescence and indirect haemoglutination. The sample of people interviewed was made up of 443 serums, 356 supposedly healthy people (mainly students) and 87, considered “high risk” (pafients from the “Reina Sofia” Hospital). The positiveness obtained for the total of the sample was 43,79 % with IFI and 53,59 % for HAI. As regards sex of the person tested, prevalence is higher in women, with 54,36 % and 70,47 % with IFI and HAI respectively, in men the scores were 38,43 % and 44,90 % for the same tests. As far as the origin of the sample was concerned, there were 31,lB % with IFI and 43,25 % for HAI of the nornal population, in the “high risk” sample, for both tests it was 9540 %. With both tests there are significative differences in low amounts, but not in high dilutions. We conclude that human toxoplasmosis is present and widespread in the studied population

The Mexican consensus on the diagnosis, treatment, and prevention of NSAID-induced gastropathy and enteropathy

Más de 30 millones de personas consumen diariamente antiinflamatorios noesteroideos (AINE) en el mundo, y este consumo se ve incrementado anualmente. Aunque losAINE poseen propiedades analgésicas y antiinflamatorias, sus eventos adversos gastrointesti-nales son bien reconocidos. En nuestro país no existía un consenso respecto al diagnóstico,tratamiento y prevención de la gastropatía y la enteropatía por AINE, por lo que la AsociaciónMexicana de Gastroenterología reunió a un grupo de expertos para establecer recomendacionesde utilidad para la comunidad médica. En este consenso se emitieron 33 recomendaciones. Elconsenso destaca que el riesgo de toxicidad gastrointestinal de los AINE varía según el fármacoempleado y su farmacocinética, lo cual debe ser considerado al momento de su prescripción. Losfactores de riesgo de complicación gastroduodenal por AINE son: antecedente de úlcera pép-tica, edad mayor a 65 a˜nos, dosis altas del AINE, infección por Helicobacter pylori (H.pylori), ypresencia de comorbilidades graves. Los síntomas y el da˜no gastroduodenal inducido por AINEson variables ya que puede cursar asintomático o manifestarse como anemia por deficiencia dehierro, hemorragia, estenosis y perforación. La cápsula endoscópica y la enteroscopia son méto-dos diagnósticos directos en la enteropatía por AINE. Respecto a la prevención, se recomiendaprescribir la dosis mínima necesaria de un AINE para obtener el efecto deseado y durante elmenor tiempo. Finalmente, los inhibidores de la bomba de protones (IBP) representan el están-dar de oro para la profilaxis y tratamiento de los efectos gastroduodenales, mas no son útilesen la enteropatía

Consenso mexicano sobre diagnóstico, prevención y tratamiento de la gastropatía y enteropatía por antiinflamatorios no esteroideos

Más de 30 millones de personas consumen diariamente antiinflamatorios no este-roideos (AINE) en el mundo y este consumo se ve incrementado a˜no tras a˜no. Aunque los AINEposeen propiedades analgésicas y antiinflamatorias, sus eventos adversos gastrointestinales sonbien reconocidos. En nuestro país no existía un consenso respecto al diagnóstico, tratamientoy prevención de la gastropatía y la enteropatía por AINE, por lo que la Asociación Mexicana deGastroenterología reunió a un grupo de expertos para establecer recomendaciones de utilidadpara la comunidad médica. En este consenso se emitieron 33 recomendaciones. El consensodestaca que el riesgo de toxicidad gastrointestinal de los AINE varía según el fármaco empleadoy su farmacocinética, lo cual debe ser considerado al momento de su prescripción. Los factoresde riesgo de complicación gastroduodenal por AINE son: antecedente de úlcera péptica, edadmayor de 65 a˜nos, dosis altas del AINE, infección por Helicobacter pylori y presencia de comor-bilidades graves. Los síntomas y el da˜no gastroduodenal inducido por AINE son variables, ya quepuede cursar asintomático o manifestarse como anemia por deficiencia de hierro, hemorragia,estenosis y perforación. La cápsula endoscópica y la enteroscopia son métodos diagnósticosdirectos en la enteropatía por AINE. Respecto a la prevención, se recomienda prescribir la dosismínima necesaria de un AINE para obtener el efecto deseado y durante el menor tiempo. Porúltimo, los inhibidores de la bomba de protones representan el estándar de oro para la profilaxisy tratamiento de los efectos gastroduodenales, mas no son útiles en la enteropatí

Supplement: "Localization and broadband follow-up of the gravitational-wave transient GW150914" (2016, ApJL, 826, L13)

This Supplement provides supporting material for Abbott et al. (2016a). We briefly summarize past electromagnetic (EM) follow-up efforts as well as the organization and policy of the current EM follow-up program. We compare the four probability sky maps produced for the gravitational-wave transient GW150914, and provide additional details of the EM follow-up observations that were performed in the different bands

Measurement of Energy Correlators inside Jets and Determination of the Strong Coupling Formula Presented

Energy correlators that describe energy-weighted distances between two or three particles in a hadronic jet are measured using an event sample of $\sqrt{s}$=13 TeV proton-proton collisions collected by the CMS experiment and corresponding to an integrated luminosity of 36.3 fb$^{−1}$. The measured distributions are consistent with the trends in the simulation that reveal two key features of the strong interaction: confinement and asymptotic freedom. By comparing the ratio of the measured three- and two-particle energy correlator distributions with theoretical calculations that resum collinear emissions at approximate next-to-next-to-leading-logarithmic accuracy matched to a next-to-leading-order calculation, the strong coupling is determined at the Z boson mass: α$_S$ (m$_Z$)=0.1229 $\frac{0.0040}{-0.0050}$ , the most precise α$_S$m$_Z$ value obtained using jet substructure observable

Search for a vector-like quark T′ → tH via the diphoton decay mode of the Higgs boson in proton-proton collisions at s \sqrt{s} = 13 TeV

A search for the electroweak production of a vector-like quark T′, decaying to a top quark and a Higgs boson is presented. The search is based on a sample of proton-proton collision events recorded at the LHC at = 13 TeV, corresponding to an integrated luminosity of 138 fb−1. This is the first T′ search that exploits the Higgs boson decay to a pair of photons. For narrow isospin singlet T′ states with masses up to 1.1 TeV, the excellent diphoton invariant mass resolution of 1–2% results in an increased sensitivity compared to previous searches based on the same production mechanism. The electroweak production of a T′ quark with mass up to 960 GeV is excluded at 95% confidence level, assuming a coupling strength κT = 0.25 and a relative decay width Γ/MT′ < 5%

Measurement of the Higgs boson inclusive and differential fiducial production cross sections in the diphoton decay channel with pp collisions at s \sqrt{s} = 13 TeV

The measurements of the inclusive and differential fiducial cross sections of the Higgs boson decaying to a pair of photons are presented. The analysis is performed using proton-proton collisions data recorded with the CMS detector at the LHC at a centre-of-mass energy of 13 TeV and corresponding to an integrated luminosity of 137 fb$^{−1}$. The inclusive fiducial cross section is measured to be $σ_{fid}$=73.4$^{+5.4}_{−5.3}$(stat)$^{+2.4}_{−2.2}$(syst) fb, in agreement with the standard model expectation of 75.4 ± 4.1 fb. The measurements are also performed in fiducial regions targeting different production modes and as function of several observables describing the diphoton system, the number of additional jets present in the event, and other kinematic observables. Two double differential measurements are performed. No significant deviations from the standard model expectations are observed

A search for new physics in central exclusive production using the missing mass technique with the CMS detector and the CMS-TOTEM precision proton spectrometer

A generic search is presented for the associated production of a Z boson or a photon with an additional unspecified massive particle X, pp → pp + Z/γ + X, in proton-tagged events from proton–proton collisions at √s = 13 TeV, recorded in 2017 with the CMS detector and the CMS-TOTEM precision proton spectrometer. The missing mass spectrum is analysed in the 600–1600 GeV range and a fit is performed to search for possible deviations from the background expectation. No significant excess in data with respect to the background predictions has been observed. odelindependent upper limits on the visible production cross section of pp → pp + Z/γ + X are set

Search for Higgs Boson Decay to a Charm Quark-Antiquark Pair in Proton-Proton Collisions at √s = 13 TeV

A search for the standard model Higgs boson decaying to a charm quark-antiquark pair, H→c¯c, produced in association with a leptonically decaying V (W or Z) boson is presented. The search is performed with proton-proton collisions at √s=13  TeV collected by the CMS experiment, corresponding to an integrated luminosity of 138  fb−1. Novel charm jet identification and analysis methods using machine learning techniques are employed. The analysis is validated by searching for Z→c¯c in VZ events, leading to its first observation at a hadron collider with a significance of 5.7 standard deviations. The observed (expected) upper limit on σ(VH)B(H→c¯c) is 0.94 (0.50+0.22−0.15)pb at 95% confidence level (C.L.), corresponding to 14 (7.6+3.4−2.3) times the standard model prediction. For the Higgs-charm Yukawa coupling modifier, κc, the observed (expected) 95% C.L. interval is 1.1<|κc|<5.5 (|κc|<3.4), the most stringent constraint to date