53 research outputs found
Avaliação da propaganda de medicamentos veiculada em emissoras de rádio
- Author
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- Field of study
Testing the Efficacy of a Multi-Component DNA-Prime/DNA-Boost Vaccine against Trypanosoma cruzi Infection in Dogs
- Author
- A Barbabosa-Pliego
- A Barbabosa-Pliego
- A Endmann
- A Rassi Jr
- AA Portela-Lindoso
- AC Moore
- Alberto Barbabosa-Pliego
- B Basso
- BC de Alencar
- C Junqueira
- CM Carneiro
- EL Silveira
- ER Lopes
- FC Goble
- FS Laranja
- FS Laranja
- JC Vázquez-Chagoyán
- JE Cohen
- JJ Donnelly
- José Antonio Zepeda-Escobar
- José E. Aparicio-Burgos
- José Simón Martínez
- JR Coura
- Juan C. Vázquez-Chagoyán
- JV Cruz-Chan
- KM Meurs
- L Piacenza
- Laucel Ochoa-García
- M de Lana
- M Dhiman
- M Weinberg
- MA Zacks
- Margarita Val Arreola
- MN Alvarez
- Monisha Dhiman
- N Garg
- N Garg
- N Garg
- Nisha Jain Garg
- NOM NOM-033-ZOO
- NOM NOM-062-ZOO
- OA Saldarriaga
- PM Guedes
- PM Guedes
- PM Guedes
- PP Bradley
- R Reithinger
- R Reithinger
- RE Gurtler
- RE Gurtler
- RE Gurtler
- RE Gurtler
- RL Cardoni
- Roberto Montes de Oca-Jiménez
- Rodrigo Correa-Oliveira
- S Gupta
- SC Barr
- SC Gilbert
- Shivali Gupta
- SI Cazorla
- T Sakai
- V Bhatia
- V Bhatia
- V Bhatia
- VM Veloso
- W Coura-Vital
- WL Tafuri
- Y Miyahira
- ZA Andrade
- ZA Andrade
- Publication venue
- Public Library of Science
- Publication date
- Field of study
Immunization of dogs with DNA-prime/DNA-boost vaccine (TcVac1) enhanced the
Trypanosoma cruzi-specific type 1 antibody and
CD8+ T cell responses that resulted in an early control of
acute parasitemia and a moderate decline in pathological symptoms during chronic
phase. Further improvement of vaccine-induced immunity would be required to
achieve clinical and epidemiological benefits and prevent transmission of
parasites from vaccinated/infected dogs to triatomines
Systemic sclerosis and idiopathic interstitial pneumonia: histomorphometric differences in lung biopsies
- Author
- Alexandre Ab'Saber
- Beon M
- Cheema GS
- Corrin B
- Cottin V
- Daniil ZD
- Edwin Roger Parra
- Erika Franco de Carvalho
- Fireman E
- Flaherty KR
- Gundersen HJ
- Katzenstein AL
- Katzenstein AL
- Leandro Hideki Otani
- Minai OA
- Montes GS
- Myers JL
- Nicholson AG
- Okada A
- Park JH
- Parra ER
- Parra ER
- Phan SH
- Presta M
- Ramirez A
- Renzoni EA
- Rozin GF
- Shahin AA
- Silver RM
- Travis WD
- Vera Luiza Capelozzi
- Wells AU
- Wells AU
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- Field of study
Spontaneous Breathing in Early Acute Respiratory Distress Syndrome: Insights From the Large Observational Study to UNderstand the Global Impact of Severe Acute Respiratory FailurE Study
- Author
- Abad RD
- Abe T
- Abroug F
- Adams JC
- Adamsson RO
- Adolfsson A
- Aguilar RZ
- Aguirre JS
- Aguirre-Bermeo H
- Aisa TM
- Aisiku I
- Ajetunmobi OO
- Aker M
- Akyol OO
- Al Dorzi HM
- Al Jabbary AS
- Albaiceta GM
- Albarrak MM
- Albiero D
- Alda RS
- Alejandro RV
- Alexander P
- Algaba Á
- Aliaga FA
- Alisasis AU
- Allan RM
- Allue RM
- Almekhlaf G
- Alonso JG
- Altaf W
- Alvarez AM
- Alvarez J
- Amin P
- Amir F
- Amor M
- An Y
- Andersen FH
- Andoh K
- Andruszkiewicz P
- Aneman A
- Antonelli MM
- Antônio ACP
- Aoki N
- Appelberg H
- Arabi Y
- Arabi YM
- Araujo AM
- Arizmendi A
- Arnal JM
- Artiga MJD
- Artigas A
- Ascoli A
- Au SM
- Avila LE
- Azad R
- Azevedo LC
- Baboi L
- Badie JC
- Bailey IM
- Bailey MB
- Bajwa E
- Balkhi H
- Baltus T
- Banner-Goodspeed VM
- Barberet G
- Baron RM
- Baronia AK
- Barratt-Due A
- Barros FM
- Barros NC
- Batra H
- Battle CE
- Bauer PR
- Beck E
- Beck O
- Bedreag OH
- Beegle SH
- Beitler JR
- Bellani G
- Bellani G.
- Beloncle F
- Ben Souissi A
- Benslama A
- Beraldo DO
- Berghe C
- Berkelmans F
- Besset SL
- Bettini LR
- Beuret P
- Bezzi MG
- Bhardwaj VK
- Bhowmick K
- Biehler J
- Bigot C
- Bihari S
- Biondi RS
- Biscione RR
- Bisso MC
- Black CS
- Blakeman TC
- Blanco J
- Bolon S
- Borello SA
- Borotto EE
- Botteri M
- Bouchoucha S
- Boukhazna M
- Bouw MJ
- Boyd O
- Bramall J
- Braschi A
- Brazzi L
- Breen DM
- Briquet A
- Brito VA
- Brizuela M
- Brochard L
- Brochard L.
- Broman LM
- Brown SM
- Browne TS
- Bruhn AR
- Brunettini B
- Bruns MM
- Buensuseso JA
- Bugedo G
- Buise MP
- Bulpa PA
- Bumbasierevic V
- Bumbasirevic V
- Burtenshaw AJ
- Burtin P
- Buzancais G
- Béduneau G
- Camsooksai J
- Canestrini S
- Cani A
- Carbayo-Gorriz C
- Cardonnet LP
- Careless JP
- Carpentier D
- Carreño NG
- Carteaux G
- Casalena P
- Casement J
- Castro AG
- Castro S
- Catorze NT
- Cazorla-Barranquero FG
- Ceniceros-Barros A
- Cereijo E
- Cerny V
- Cerrato VI
- Cesar PS
- Ceunen H
- Ceylan I
- Chabanne R
- Chapman R
- Chau SK
- Chelly J
- Chen K
- Chena A
- Cheng MP
- Chiche JD
- Chouchene I
- Choudry S
- Christiansen A
- Cimic N
- Cinnella G
- Cirone R
- Citalán JE
- Claraco-Vega LM
- Clarkson K
- Clarkson KP
- Claverias L
- Cohen JE
- Cole JM
- Collins DV
- Collyer T
- Colombo R
- Combaux DM
- Combes A
- Cooper R
- Coppadoro A
- Corneci DE
- Cortegiani A
- Cortez CA
- Coxo CM
- Cracchiolo AN
- Cranshaw JH
- Crapelli G
- Crouch DR
- Crova PJ
- Csabi P
- Curley G
- Curto EG
- Daldin J
- Dangers L
- Danin PE
- Daubin C
- Daviaud F
- Davies KG
- Dawson H
- De Cima-Iglesias S
- De Gordoa LO
- De Haro C
- De Pablo R
- de Prost N
- Dean MN
- Declercq PM
- Dector D
- Dector DM
- Deicas A
- Dellamonica J
- Dellera C
- Delsing A
- Demirkiran O
- Demoule A
- Dempsey G
- Dendane T
- Depuyd P
- Depuydt P
- Derman SS
- Di Tomasso NN
- Di YD
- Diaz-Rodriguez E
- Dive AM
- Dixit SB
- Dolva MS
- Donnelly A
- Dowling AT
- Doyen D
- Dres M
- Dres M.
- Dreyer KR
- Dunne ES
- Dupont H
- Duranteau J
- Dwyer R
- Démpaire G
- Elatrous S
- Elisabet GM
- Elkhayari M
- Ellis HE
- Elmasri M
- Erbabacan E
- Eriksson KE
- Esteban A
- Estenssoro E
- Esteve F
- Estilita JM
- Estrella CR
- Eugenio Luis PS
- Ezzouine H
- Fan E
- Fan E.
- Fartoukh M
- Farías PA
- Fawkes DA
- Ferguson A
- Ferguson ND
- Fernandes ADV
- Fernandez AM
- Fernandez RO
- Fierro JM
- Floris L
- Follin A
- Fontenele DC
- Formenti P
- Forteza C
- Fossali T
- Foti G
- Franco N
- Frati E
- Frendl G
- Frigyik AD
- Fusari M
- Futami S
- Gally J
- Ganesan D
- Gao Y
- Gao YN
- Garcia PH
- Gattinoni L
- Gazenkampf AA
- Gelée B
- George FG
- Ghazi M
- Gianinetto H
- Giarratano A
- Gillis S
- Girgin NK
- Gjedsted J
- Glietsch R
- Goldgran-Toledano D
- Goligher E. C.
- Goligher EC
- Gomaa D
- Gomaa D
- Gomes RM
- Gomez PE
- Gomez-Flores SS
- Gonzalez DR
- Gonzalez M
- González RM
- González Rojas MA
- González-Salamanca Á
- Gonçalves CH
- Goodson JC
- Gordo F
- Gosselin RJ
- Goubaux B
- Graziani R
- Grelon F
- Griffin RO
- Grigoriev E
- Grijalba CQ
- Grissom CK
- Gritsan AI
- Grubissich N
- Gueret RM
- Gurjar M
- Guttormsen AB
- Guérin C
- Gómez PRA
- Hacking DJ
- Haddad Y
- Hadfield D
- Hagan SJ
- Han H
- Han Y
- Hang AY
- Hanlon GC
- Harasawa T
- Harrois A
- Hashemian SM
- Hashida T
- He Z
- Hedlund L
- Heidari F
- Heines SJ
- Helleberg J
- Henderson G
- Herbrecht JE
- Hermosa C
- Hessell RJ
- Heunks L.
- Heunks LM
- Heunks LM
- Higashijima U
- Hirata A
- Holzgraefe B
- Honda H
- Honrubia T
- Hopf HF
- Hopkins P
- Hormis AP
- Hou PC
- Hou SK
- Hraiech S
- Hua MX
- Huang QQ
- Huang XB
- Huerta FP
- Huff NG
- Humphreys SK
- Hunt A
- Hurtado J
- Hurtado J
- Hurtado J
- Hutchison RA
- Hutton PJ
- Ibañez-Santacruz M
- Ichikado K
- Iglesias Moles S
- Ilaria Pattarino PT
- Ilutovich S
- Imai H
- Imma VP
- Imperio MC
- Insaurralde CS
- Inskip DM
- Ioannou N
- Iotti GA
- Irvine DA
- Ismail D
- Ismail M
- Ito F
- Izawa M
- Jaafar RF
- Jakubowska K
- Jamaati H
- Jarquin-Badiola YD
- Jassal M
- Javeed A
- Jha RR
- Jiang L
- Jibaja M
- Jimenez AG
- Jochmans S
- Jog SA
- Jovanovic B
- Judy C
- Jurado MT
- Kadaba V
- Kajtor I
- Kakar V
- Kalaitzis E
- Kalkoff M
- Kamel G
- Kameyama Y
- Kamoun S
- Kander T
- Kannan SG
- Kashiwa Y
- Kedelv H
- Kennedy B
- Khebbeb S
- Kheir F
- Kheir FM
- Kimura H
- Kiourtzieva EV
- Kitch BT
- Knapman KM
- Knoll J
- Knowles S
- Kol MR
- Kong J
- Koyama K
- Kraßler J
- Krstevski A
- Kulkarni S
- Kumar A
- Kurahashi K
- Kusumoto K
- Laake JH
- Laake JH
- Labarca EF
- Laffey J
- Laffey J.
- Laffey JG
- Lamb KD
- Lanspa MJ
- Larsson A
- Larsson A
- Larsson N
- Le Moal C
- Lebbinck H
- Lee J
- Leemann-Refondini C
- Lemiale V
- Lemus JS
- Leon Yoshido HH
- Li B
- Li Q
- Li QJ
- Li W
- Li X
- Li XL
- Li Y
- Li YY
- Li-Xin Z
- Liew KY
- Ling LL
- Liu J
- Liu JL
- Liu L
- Llano M
- Llinares Moya DD
- Lohner R
- Loiacono FA
- Lombardo A
- Lopez EB
- Lopez-Delgado JC
- Lora FS
- Lora P
- Lorente JA
- Lorente MDC
- Losada EP
- Lovazzano P
- Lu W
- Lu Y
- Luo X
- Lynch J.
- Lynch JM
- Maazouzi W
- Macfadyen R
- MacFie CC
- Maeyama HN
- Maghrabi KA
- Magret M
- Mahto HL
- Mancebo J
- Manoharan V
- Marcos DP
- Marcu A
- Marin J
- Marin MC
- Martinez FT
- Martinho AM
- Marum SM
- Massa EV
- Mataloun S
- Matamis D
- Matsumoto S
- Mattei A
- May MM
- Mcarthur C
- McAuley D
- McAuley D
- McAuley DF
- McAuley DF
- McCalman KH
- Mckechnie S
- Mckee R
- Mckenna TE
- Mcleod A
- McNamee L
- McNamee L
- Meaney EA
- Meco BC
- Meersseman P
- Mehta S
- Mejia FJF
- Mellis C
- Memon M
- Mercat A
- Mesar T
- Mesar T
- Messias AM
- Messika J
- Meybohm P
- Michel P
- Millar RT
- Miller JJ
- Miller RR
- Mirabella L
- Mizuguchi I
- Mochizuki K
- Mohammadreza Hashemian S
- Mohr NM
- Mojoli F
- Molin A
- Montanha GM
- Monteiro JM
- Montero LA
- Montes Oscanoa FA
- Monti G
- Montini LM
- Moock M
- Morin AK
- Mortaza S
- Morton A
- Mouloudi EK
- Mukkera SR
- Mustafa GM
- Muthuchellappan R
- Máca J
- Nagy EO
- Nakamura T
- Namih M
- Nassar AP Jr
- Nasu M
- Navalpotro MAB
- Navarra L
- Navarro G
- Neal J
- Negoita SI
- Newby L
- Nichol A
- Nielsen J
- Nielsen J
- Niimi D
- Nin N
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- Nishikawa E
- Nitta K
- Nobrega D
- Noremark KAL
- Nunci L
- Nunes SL
- Nunomiya S
- Nutt C
- Nuñez E
- Nygren I
- O'Croinin D
- O'Kane SC
- O'Muircheartaigh AC
- O'Neill O
- Occhipinti G
- Oetting TW
- Ogino Y
- Oikonomou MA
- Okuda N
- Oldroyd MG
- Olga MF
- Oliveira BS
- Ortiz CA
- Osman EM
- Oss P
- Ouanes I
- Ourailogloy V
- Owens RL
- Ozcelik M
- Palaniswamy V
- Palma DM
- Palmese S
- Palo JE
- Panarello G
- Papanikolaou MN
- Papavasilopoulou TG
- Papazian L
- Papurica M
- Para LH
- Parhar K
- Parotto M
- Pasanting-Lim RAB
- Patroniti N
- Pecci E
- Pellegrini CA
- Pelletier N
- Pellicer AM
- Penuelas O
- Pereira CS
- Perez CP
- Perez MP
- Persson L
- Pesenti A
- Pg Hj Ismail DMAB
- Pham T
- Pham T
- Pham T.
- Phan NT
- Piacentini EA
- Pillai S
- Pintado MC
- Piquilloud L
- Piquilloud L
- Piras C
- Pittini G
- Plotnikow GA
- Poblano M
- Poli MM
- Pota V
- Pozo NC
- Pozzi M
- Preez PD
- Prieto-González M
- Pronovost A
- Protti A
- Qin B
- Qin J
- Qin SH
- Qin TH
- Qiu H
- Qiu H
- Raaijmakers M
- Rafael SI
- Raimondi F
- Raj AS
- Ramakrishnan N
- Ramesh VJ
- Ramirez Cervantes M
- Ramirez-Alfaro CM
- Ramirez-Gutierrez A
- Rampinelli AM
- Ranero JL
- Ranieri M
- Raponi F
- Recio NN
- Reschreiter H
- Reske AW
- Reuter D
- Reynolds C
- Rhayakar RV
- Rialp G
- Richecoeur JR
- Ricome S
- Rigaud JP
- Rinia M
- Rios F
- Riss KC
- Rittayamai N
- Roberts BL
- Robine A
- Robles JB
- Roche-Campo F
- Rodgers HJ
- Rodriguez LL
- Rodriguez R
- Rosa JI
- Roser TP
- Rossi A
- Roux D
- Rubenfeld G
- Rugonfalvi S
- Ruiz SR
- Ruiz-Aguilar AL
- Rylander CC
- Ryosuke S
- Sabelnikovs O
- Sable SD
- Saenz MG
- Saez AA
- Sagar SV
- Saito K
- Saito S
- Salahuddin N
- Salas JE
- Sales VM
- Samkaoui N
- Sanchez RJ
- Sanchez-Hurtado LA
- Sanchez-Medina JR
- Sandesc D
- Santoli FL
- Santos C
- Sauvadet EP
- Savioli M
- Scafetti S
- Schiavone V
- Schiavoni L
- Schiöler F
- Schlichting AB
- Schneider F
- Schomer A
- Schouten JA
- Schuetz M
- Schultz MJ
- Schäfer S
- Scott CJ
- Seasman C
- Seethala R
- Sellors GP
- Seoane-Quiroga L
- Serra C
- Serra IM
- Setten MG
- Seven A
- Shah B
- Shao H
- Shen J
- Shenoy A
- Sher S
- Shimizu K
- Shindhe S
- Shinn JO 3rd
- Shiozaki K
- Silesky J
- Silesky Jimenez JI
- Sim M
- Simon P
- Simonis FD
- Sivashanmugavel M
- Sjøbø BÅ
- Sklienka P
- Slutsky AS
- Smith MJ
- Smith O
- Soler JA
- Solis-Quesada JE
- Sotillo Diaz JCJ
- Sottiaux T
- Spadaro S
- Srinivasa L
- Stamou EE
- Staudinger T
- Stephenson L
- Stewart R
- Stigler W
- Strauch U
- Sula H
- Sun R
- Surbatovic M
- Suzuki H
- Szakmany T
- Sánchez RM
- Sánchez-Ballesteros J
- Søreide E
- Tabhan E
- Tabhan EE
- Tainter C
- Takaba A
- Takada T
- Takagi S
- Tallet Alfonso AA
- Tan BC
- Tanaka H
- Tang R
- Tapponnier R
- Tarantino F
- Temprano S
- Terzi N
- Thibault S
- Thomas M
- Thompson BT
- Thompson MM
- Tibblin AO
- Tinnirello A
- Tiribelli N
- Todeschini M
- Tomescu DR
- Toribio DP
- Toth-Tarsoly P
- Treanor N
- Trinder TJ
- Trinidad OA
- Tulaimat A
- Twohey L
- Uchiyama A
- Ueda T
- Ueno K
- Umbrello M
- Unnikrishnan R
- Uppalapati A
- van Haren F
- van Haren F.
- Van Wezel HM
- Vargas MP
- Vascotto ER
- Vasquez DN
- Vega LD
- Veljovic M.
- Venti A
- Vercueil A
- Vermassen J
- Verstraete R
- Villagomez A
- Villagomez AJ
- Villamagua BG
- Villar V
- Vinzio M
- Virgilio CG
- Vitale MN
- Volta CA
- Wang C
- Wang HX
- Wang SH
- Wang W
- Warren J
- Watanabe E
- Watt P
- Welters ID
- Wenham T
- Wessbergh J
- Whitehead C
- Willett EL
- Williams AJ
- Williams KE
- Wise MP
- Wittebole X
- Wong HS
- Woods PW
- Wrathall DW
- Wrigge H
- Wrigge H
- Wrigge H.
- Wu YQ
- Xin-Hua Q
- Xu Y
- Yamaguchi O
- Yamaji Y
- Yao Q
- Ye ZL
- Yeatts DJ
- Yu R
- Yu T
- Yu W
- Yumha JS
- Yuste LJ
- Zacharas GA
- Zacharowsk KD
- Zani G
- Zantua KS
- Zazu A
- Zeggwagh AA
- Zeggwagh AA
- Zein SO
- Zender HO
- Zhai Z
- Zhang F
- Zhang XY
- Zhao H
- Zhao J
- Zhao XY
- Zheng R
- Zhou FC
- Zhou S
- Zhu BH
- Zhu WH
- Zogheib EH
- Ñamendys-Silva SA
- Ünal N
- Publication venue
- 'Ovid Technologies (Wolters Kluwer Health)'
- Publication date
- 01/01/2019
- Field of study
OBJECTIVES: To describe the characteristics and outcomes of patients with acute respiratory distress syndrome with or without spontaneous breathing and to investigate whether the effects of spontaneous breathing on outcome depend on acute respiratory distress syndrome severity. DESIGN: Planned secondary analysis of a prospective, observational, multicentre cohort study. SETTING: International sample of 459 ICUs from 50 countries. PATIENTS: Patients with acute respiratory distress syndrome and at least 2 days of invasive mechanical ventilation and available data for the mode of mechanical ventilation and respiratory rate for the 2 first days. INTERVENTIONS: Analysis of patients with and without spontaneous breathing, defined by the mode of mechanical ventilation and by actual respiratory rate compared with set respiratory rate during the first 48 hours of mechanical ventilation. MEASUREMENTS AND MAIN RESULTS: Spontaneous breathing was present in 67% of patients with mild acute respiratory distress syndrome, 58% of patients with moderate acute respiratory distress syndrome, and 46% of patients with severe acute respiratory distress syndrome. Patients with spontaneous breathing were older and had lower acute respiratory distress syndrome severity, Sequential Organ Failure Assessment scores, ICU and hospital mortality, and were less likely to be diagnosed with acute respiratory distress syndrome by clinicians. In adjusted analysis, spontaneous breathing during the first 2 days was not associated with an effect on ICU or hospital mortality (33% vs 37%; odds ratio, 1.18 [0.92-1.51]; p = 0.19 and 37% vs 41%; odds ratio, 1.18 [0.93-1.50]; p = 0.196, respectively ). Spontaneous breathing was associated with increased ventilator-free days (13 [0-22] vs 8 [0-20]; p = 0.014) and shorter duration of ICU stay (11 [6-20] vs 12 [7-22]; p = 0.04). CONCLUSIONS: Spontaneous breathing is common in patients with acute respiratory distress syndrome during the first 48 hours of mechanical ventilation. Spontaneous breathing is not associated with worse outcomes and may hasten liberation from the ventilator and from ICU. Although these results support the use of spontaneous breathing in patients with acute respiratory distress syndrome independent of acute respiratory distress syndrome severity, the use of controlled ventilation indicates a bias toward use in patients with higher disease severity. In addition, because the lack of reliable data on inspiratory effort in our study, prospective studies incorporating the magnitude of inspiratory effort and adjusting for all potential severity confounders are required
Identifying associations between diabetes and acute respiratory distress syndrome in patients with acute hypoxemic respiratory failure: an analysis of the LUNG SAFE database
- Author
- Abad Rd
- Abe T
- Abroug F
- Adams Jc
- Adamsson Ro
- Adolfsson A
- Aguilar Rz
- Aguirre Js
- Aguirre-Bermeo H
- Aisa Tm
- Aisiku I
- Ajetunmobi Oo
- Aker M
- Akyol Oo
- Al Dorzi Hm
- Al Jabbary As
- Albaiceta Gm
- Albarrak Mm
- Albiero D
- Alda Rs
- Alejandro Rv
- Alexander P
- Algaba Á
- Aliaga Fa
- Alisasis Au
- Allan Rm
- Allue Rm
- Almekhlafi G
- Alonso Jg
- Altaf W
- Alvarez Am
- Alvarez J
- Amin P
- Amir F
- Amor M
- An Y
- Andersen Fh
- Andoh K
- Andruszkiewicz P
- Aneman A
- Antonelli Mm
- Antônio Acp
- Aoki N
- Appelberg H
- Arabi Y
- Arabi Ym
- Arabi Ym
- Araujo Am
- Arizmendi A
- Arnal Jm
- Artiga Mjd
- Artigas A
- Ascoli A
- Au Sm
- Avila Le
- Azad R
- Azevedo Lc
- Baboi L
- Badie Jc
- Bailey Im
- Bailey Mb
- Bajwa E
- Balkhi H
- Baltus T
- Banner-Goodspeed Vm
- Barberet G
- Baron Rm
- Baronia Ak
- Barratt-Due A
- Barros Fm
- Barros Nc
- Batra H
- Battle Ce
- Bauer Pr
- Beck E
- Beck O
- Bedreag Oh
- Beegle Sh
- Beitler Jr
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- Zogheib Eh
- Ñamendys-Silva Sa
- Ünal N
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2018
- Field of study
Background: Diabetes mellitus is a common co-existing disease in the critically ill. Diabetes mellitus may reduce the risk of acute respiratory distress syndrome (ARDS), but data from previous studies are conflicting. The objective of this study was to evaluate associations between pre-existing diabetes mellitus and ARDS in critically ill patients with acute hypoxemic respiratory failure (AHRF). Methods: An ancillary analysis of a global, multi-centre prospective observational study (LUNG SAFE) was undertaken. LUNG SAFE evaluated all patients admitted to an intensive care unit (ICU) over a 4-week period, that required mechanical ventilation and met AHRF criteria. Patients who had their AHRF fully explained by cardiac failure were excluded. Important clinical characteristics were included in a stepwise selection approach (forward and backward selection combined with a significance level of 0.05) to identify a set of independent variables associated with having ARDS at any time, developing ARDS (defined as ARDS occurring after day 2 from meeting AHRF criteria) and with hospital mortality. Furthermore, propensity score analysis was undertaken to account for the differences in baseline characteristics between patients with and without diabetes mellitus, and the association between diabetes mellitus and outcomes of interest was assessed on matched samples. Results: Of the 4107 patients with AHRF included in this study, 3022 (73.6%) patients fulfilled ARDS criteria at admission or developed ARDS during their ICU stay. Diabetes mellitus was a pre-existing co-morbidity in 913 patients (22.2% of patients with AHRF). In multivariable analysis, there was no association between diabetes mellitus and having ARDS (OR 0.93 (0.78-1.11); p = 0.39), developing ARDS late (OR 0.79 (0.54-1.15); p = 0.22), or hospital mortality in patients with ARDS (1.15 (0.93-1.42); p = 0.19). In a matched sample of patients, there was no association between diabetes mellitus and outcomes of interest. Conclusions: In a large, global observational study of patients with AHRF, no association was found between diabetes mellitus and having ARDS, developing ARDS, or outcomes from ARDS. Trial registration: NCT02010073. Registered on 12 December 2013
Epidemiology and patterns of tracheostomy practice in patients with acute respiratory distress syndrome in ICUs across 50 countries
- Author
- Abad RD
- Abe T
- Abe T.
- Abroug F
- Adams JC
- Adamsson RO
- Adolfsson A
- Aguilar RZ
- Aguirre JS
- Aguirre-Bermeo H
- Aisa TM
- Aisiku I
- Ajetunmobi OO
- Aker M
- Akyol OO
- Al Dorzi HM
- Al Jabbary AS
- Albaiceta GM
- Albarrak MM
- Albiero D
- Alda RS
- Alejandro RV
- Alexander P
- Algaba Á
- Aliaga FA
- Alisasis AU
- Allan RM
- Allue RM
- Almekhlafi G
- Alonso JG
- Altaf W
- Alvarez AM
- Alvarez J
- Amin P
- Amir F
- Amor M
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- Andersen FH
- Andoh K
- Andruszkiewicz P
- Aneman A
- Antonelli MM
- Antônio ACP
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- Appelberg H
- Arabi Y
- Arabi YM
- Arabim YM
- Araujo AM
- Arizmendi A
- Arnal JM
- Artiga MJD
- Artigas A
- Ascoli A
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- Badie JC
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- Banner-Goodspeed VM
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- Beitler JR
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- Bellani G.
- Beloncle F
- Benslama A
- Beraldo DO
- Berghe C
- Berkelmans F
- Besset SL
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- Bhardwaj VK
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- Bihari S
- Biondi RS
- Biscione RR
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- Borello SA
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- Bumbasierevic V
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- Buzancais G
- Béduneau G
- Camsooksai J
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- Cardonnet LP
- Careless JP
- Carpentier D
- Carreño NG
- Carteaux G
- Casalena P
- Casement J
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- Catorze NT
- Cazorla-Barranquero FG
- Ceniceros-Barros A
- Cereijo E
- Cerny V
- Cerrato VI
- Cervantes MR
- Cesar PS
- Ceunen H
- Ceylan I
- Chabanne R
- Chapman R
- Chau SK
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- Chiche JD
- Chile SC
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- Daldin J
- Dangers L
- Danin PE
- Daubin C
- Daviaud F
- Davies KG
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- de Cima-Iglesias S
- de Gordoa LO
- de Haro C
- de Pablo R
- de Prost N
- Dean MN
- Declercq PM
- Dector D
- Dector DM
- Deicas A
- Del Carmen Lorente M
- Dellamonica J
- Dellera C
- Delsing A
- Demirkiran O
- Demoule A
- Dempsey G
- Dendane T
- Depuydt P
- Depuydt P
- Derman SS
- Di Tomasso NN
- Di YD
- Diaz-Rodriguez E
- Dive AM
- Dixit SB
- do Vale Fernandes A
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- Donnelly A
- Dowling AT
- Doyen D
- Dres M
- Dreyer KR
- Dunne ES
- Dupont H
- Duranteau J
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- Démpair G
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- Francois GM
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- Frigyik AD
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- Futami S
- Gally J
- Ganesan D
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- Gazenkampf AA
- Gelée B
- General H
- George FG
- Ghazi M
- Gianinetto H
- Giarratano A
- Gillis S
- Girgin NK
- Gjedsted J
- Glietsch R
- Goldgran-Toledano D
- Goligher EC
- Gomaa D
- Gomaa D
- Gomes RM
- Gomez PE
- Gomez-Flores SS
- Gonzalez DR
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- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2018
- Field of study
Background: To better understand the epidemiology and patterns of tracheostomy practice for patients with acute respiratory distress syndrome (ARDS), we investigated the current usage of tracheostomy in patients with ARDS recruited into the Large Observational Study to Understand the Global Impact of Severe Acute Respiratory Failure (LUNG-SAFE) study. Methods: This is a secondary analysis of LUNG-SAFE, an international, multicenter, prospective cohort study of patients receiving invasive or noninvasive ventilation in 50 countries spanning 5 continents. The study was carried out over 4 weeks consecutively in the winter of 2014, and 459 ICUs participated. We evaluated the clinical characteristics, management and outcomes of patients that received tracheostomy, in the cohort of patients that developed ARDS on day 1-2 of acute hypoxemic respiratory failure, and in a subsequent propensity-matched cohort. Results: Of the 2377 patients with ARDS that fulfilled the inclusion criteria, 309 (13.0%) underwent tracheostomy during their ICU stay. Patients from high-income European countries (n = 198/1263) more frequently underwent tracheostomy compared to patients from non-European high-income countries (n = 63/649) or patients from middle-income countries (n = 48/465). Only 86/309 (27.8%) underwent tracheostomy on or before day 7, while the median timing of tracheostomy was 14 (Q1-Q3, 7-21) days after onset of ARDS. In the subsample matched by propensity score, ICU and hospital stay were longer in patients with tracheostomy. While patients with tracheostomy had the highest survival probability, there was no difference in 60-day or 90-day mortality in either the patient subgroup that survived for at least 5 days in ICU, or in the propensity-matched subsample. Conclusions: Most patients that receive tracheostomy do so after the first week of critical illness. Tracheostomy may prolong patient survival but does not reduce 60-day or 90-day mortality. Trial registration: ClinicalTrials.gov, NCT02010073. Registered on 12 December 2013
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- Publication venue
- OXFORD UNIV PRESS
- Publication date
- 29/10/2019
- Field of study
Document recommendation systems for locating relevant literature have mostly relied on methods developed a decade ago. This is largely due to the lack of a large offline gold-standard benchmark of relevant documents that cover a variety of research fields such that newly developed literature search techniques can be compared, improved and translated into practice. To overcome this bottleneck, we have established the RElevant LIterature SearcH consortium consisting of more than 1500 scientists from 84 countries, who have collectively annotated the relevance of over 180 000 PubMed-listed articles with regard to their respective seed (input) article/s. The majority of annotations were contributed by highly experienced, original authors of the seed articles. The collected data cover 76% of all unique PubMed Medical Subject Headings descriptors. No systematic biases were observed across different experience levels, research fields or time spent on annotations. More importantly, annotations of the same document pairs contributed by different scientists were highly concordant. We further show that the three representative baseline methods used to generate recommended articles for evaluation (Okapi Best Matching 25, Term Frequency–Inverse Document Frequency and PubMed Related Articles) had similar overall performances. Additionally, we found that these methods each tend to produce distinct collections of recommended articles, suggesting that a hybrid method may be required to completely capture all relevant articles. The established database server located at https://relishdb.ict.griffith.edu.au is freely available for the downloading of annotation data and the blind testing of new methods. We expect that this benchmark will be useful for stimulating the development of new powerful techniques for title and title/abstract-based search engines for relevant articles in biomedical research
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1.
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- Zhuang H
- Zhuang X
- Zientara-Rytter K
- Zimmermann CM
- Ziviani E
- Zoladek T
- Zong W-X
- Zorov DB
- Zorzano A
- Zou W
- Zou Z
- Zou Z
- Zuryn S
- Zwerschke W
- Álvarez ÉMC
- Ávalos Y
- Önal G
- Üstün S
- Čolić M
- Đokić J
- Žerovnik E
- Publication venue
- 'Informa UK Limited'
- Publication date
- 01/01/2021
- Field of study
In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes. These guidelines are not meant to be a dogmatic set of rules, because the appropriateness of any assay largely depends on the question being asked and the system being used. Moreover, no individual assay is perfect for every situation, calling for the use of multiple techniques to properly monitor autophagy in each experimental setting. Finally, several core components of the autophagy machinery have been implicated in distinct autophagic processes (canonical and noncanonical autophagy), implying that genetic approaches to block autophagy should rely on targeting two or more autophagy-related genes that ideally participate in distinct steps of the pathway. Along similar lines, because multiple proteins involved in autophagy also regulate other cellular pathways including apoptosis, not all of them can be used as a specific marker for bona fide autophagic responses. Here, we critically discuss current methods of assessing autophagy and the information they can, or cannot, provide. Our ultimate goal is to encourage intellectual and technical innovation in the field
Pooled analysis of WHO Surgical Safety Checklist use and mortality after emergency laparotomy
- Author
- Aahlin EK
- Aamer A
- Aaniana K
- Ababneh A
- Abaliksta T
- Abantanga F
- Abantanga F
- Abbas A
- Abbas M
- Abbasy J
- Abbo O
- Abbo O
- Abbott T
- Abbouch M
- Abd El Galeel A
- Abd El Hameed OS
- Abd El Hamid N
- Abd El Salam Y
- Abd El Slam M
- Abd El-Salam F
- Abd Elrasoul Y
- Abd-Elmawla M
- Abd-Elrasoul Y
- Abdallah E
- Abdallah E
- Abdel-Aty A
- Abdel-Hameed N
- Abdel-Kader SM
- Abdel-Wahab NYE
- Abdelaal A
- Abdelaty M
- Abdelazeam AR
- Abdelazim G
- Abdelaziz MA
- Abdelbadeai K
- Abdelfatah A
- AbdelFattah I
- Abdelgelil A
- Abdelghany S
- Abdelhady S
- Abdelhamed R
- Abdelhamid A
- Abdelhaq A
- Abdelkader M
- Abdelkader M
- Abdelkader O
- Abdelkareem A
- Abdelkhalek M
- Abdelmageed E
- Abdelmotaleb I
- Abdelraheim M
- Abdelraouf AM
- Abdelrouf DM
- Abdelshafy M
- Abdelshakour M
- Abdrabou AK
- Abdul-Latif S
- Abdulaziz H
- Abdulaziz M
- Abdulbagi O
- Abdulgawad M
- Abdulhakeem EM
- Abdullah AAN
- Abdullah MA
- Abdullah N
- Abdullah NAN
- Abdullah NAN
- Abdullahi L
- Abdurrazzaaq A
- Abebe NS
- Abebe NS
- Abem OE
- Aber A
- Abington E
- Abiola O
- Aboarab A
- Aboelella M
- Aboelmagd O
- Aboelsoud MR
- Aboraya M
- Aboraya M
- Abouelnasr A
- Aboul-Naga MS
- Abouzahra A
- Abouzaid A
- Abozaid M
- Abozeid K
- Abozyed MAF
- Abu Qumbos A
- Abu-toyour M
- Abubakr M
- Abudeeb H
- Abuowda Y
- Abuqwaider E
- Abusalem L
- Abuseif M
- Abushamleh S
- Acharya P
- Ackom E
- Acquah E
- Adam A
- Adam N
- Adams R
- Adamu A
- Adawi I
- Adawi M
- Adebanjo A
- Adebanjo A
- Adebola O
- Adedeji A
- Adekoya A
- Adel A
- Adel A
- Adel BE
- Adel I
- Adella FJ
- Adelshone A
- Ademuyiwa A
- Ademuyiwa A
- Ademuyiwa AO
- Ademuyiwa AO
- Ademuyiwa AO
- Ademuyiwa AO
- Adenekan B
- Adeniran J
- Adeniran J
- Adeniyi A
- Adeniyi A
- Adesanya O
- Adesanya O
- Adesina A
- Adesina A
- Adesuyi A
- Adeyeye A
- Adeyeye A
- Adeyeye A
- Adham W
- Adhitama N
- Adil M
- Adisa AO
- Adisa AO
- Adu-Aryee N
- Afana S
- Afandy A
- Afifi AM
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- Agalianos C
- Agarwal A
- Agarwal A
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- Agbedinu K
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- Aglan A
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- Ahlonsou G
- Ahlqvist S
- Ahlqvist S
- Ahlqvist S
- Ahmed A
- Ahmed A
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- Ahounou EYS
- Aigrain Y
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- Al Saied G
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- Al-Aarag AA-R
- Al-Azraqi IAA
- Al-Bahrani A
- Al-Buhaisi A
- Al-Dakka E
- Al-Faifi JJ
- Al-faqawi M
- Al-farram H
- Al-Hameedi HII
- Al-Hasani RKMJ
- Al-khatib A
- Al-Mallah A
- Al-Marakby D
- Al-Mousa M
- Al-Nahrawi S
- Al-Obaedi O
- Al-saqqa S
- Al-Saqqa SW
- Al-Saqqa SW
- Al-shammari A
- Al-Slaibi I
- Al-taher T
- Alaael-Dein S
- Alada M
- Alahmady O
- Alakaloko F
- Alakaloko F
- Alaloul E
- Alamin S
- Alamoudi M
- Alamoudi U
- Albeladi B
- Albiety A
- Alcca Ticona W
- Aldalaq A
- Aldhafeeri S
- Aledrisy M
- Alejos Bermudez YE
- Alexander P
- Alexander P
- Alexander P
- Alexandre C
- Alfarsi MA
- Alghamdi A
- Alghamdi B
- Alghamdi M
- Alghamdi MSA
- Algohary O
- Alhabli I
- Alhady K
- Alhammali T
- Alhassan B
- Alhazmi W
- Alhendy M
- Alherz M
- Ali A
- Ali A
- Ali A
- Ali CDM
- Ali E
- Ali FM
- Ali H
- Ali S
- Ali SAWEW
- Ali SS
- Ali THA
- Ali W
- Alihonou T
- Alimi Q
- Alis H
- Aliyu H
- Aliyu M
- Aliyu S
- Aljboor K
- Aljiffry M
- Aljiffry M
- Aljohani E
- Aljohani E
- Aljohani S
- Alkaaki A
- Alkammash A
- Alkelani M
- Alkhabbaz D
- Alkhouri M
- Allam M
- Allam M
- Allam Y
- Allegri A
- Allegri A
- Allen JLY
- Allott R
- Almallah A
- Almoflihi A
- Almuallem S
- Almy J
- Alnaby MH
- Alnawam E
- Alnuqaydan SA
- Alnusairat A
- Alomar IN
- Alqahtani E
- Alqahtani S
- Alrahawy M
- Alrajraji M
- Alrifaie A
- AlRowais M
- Alsaggaf M
- Alsaggaf MU
- Alsaggaf MU
- Alser OH
- Alshareef R
- Altaf A
- Altaf A
- Altamimi A
- Altamimi A
- Altamimi A
- Altamimi A
- Altamini A
- Altarayra M
- Althwainy A
- Altibi A
- Altinel Y
- Altinel Y
- Altoe F
- Altwigry AM
- Altwijri A
- Alvarado Jaramillo R
- Alvarez Barreda LM
- Alvi AR
- Alwafai MG
- Aly AK
- Aly MYM
- Alyacoubi S
- Alyahya R
- Alyami R
- Alyami R
- AlYoussef I
- Alzahrani A
- Alzahrani M
- Alzahrani M
- Alzayat T
- Aman NF
- Amandito R
- Amandito R
- Amandito R
- Amandito R
- Ambrona-Zafra D
- Ambrozeviciute V
- Ameen M
- Amer MA
- Amin HAA
- Amin J
- Amin J
- Amjad M
- Ammar M
- Ammar MS
- Amoah M
- Amoako J
- Amoako PT
- Amoako-Boateng M
- Amole I
- Amreia M
- Amreia M
- Anandkumar D
- Anderson D
- Anderson F
- Anderson R
- Anderson-Knight H
- Andersson L
- Andika FFA
- Andreotti D
- Andres Garcia-Marin J
- Andress C
- Andriola V
- Ang YL
- Angelieri D
- Anis E
- Ansaloni L
- Ansaloni L
- Ansaloni L
- Ansaloni L
- Ansaloni L
- Antar S
- Antezana D
- Anthoulakis C
- Anthoulakis C
- Antoniozzi A
- Anwar AW
- Anwar N
- Anwer W
- Anyanwu L-J
- Anyanwu L-J
- Aonzo P
- Appeadu-Mensah W
- Appiah EK
- Aql S
- Aquilino F
- Arachchi PP
- Arachchige LAJJ
- Arafa O
- Arafa S
- Arango MCM
- Arango MCM
- Aranzabal Durand SY
- Araujo R
- Arcudi C
- Ardley R
- Arenas A
- Arevalo Azmitia JR
- Arias Pacheco RD
- Arman S
- Arman S
- Armando ChunguiBravo J
- Armellini A
- Arnaud A
- Arnaud AP
- Arnaud AP
- Arnaud AP
- Arroyo Basto CA
- Arshad MM
- Arslan E
- Arsyad HM
- Arthur T
- Arulampalam T
- Aruldas N
- Asal M
- Asar YH
- Asare-Bediako K
- Asele FA
- Ashour A
- Ashour A
- Ashour K
- Ashraf SF
- Ashtari M
- Ashton A
- Asi F
- Asilah SMD
- Assal A
- Assouto PA
- Asturia S
- Asumah H
- Ata A
- Ata AAA
- Ata AY
- Atiyeh A
- Atkins ET
- Atkinson K
- Atobatele K
- Attallah NA
- Attard M
- Attia A
- Attia AM
- Augestad KM
- Aung KP
- Austraite A
- Aviles S
- Avoka A
- Awad I
- Awad SA
- Awadallah S
- Awuku-Asabre J
- Ayad S
- Ayandipo O
- Ayandipo OO
- Aydin MC
- Ayyar S
- Aziz DNA
- Aziz MRA
- Aziz NA
- Azizeldine MG
- Azmitia Mendizabal CA
- Azodo IA
- Azzie G
- Azzie G
- Azzis O
- Baba S
- Bachri H
- Badawy M
- Badenjki MA
- Badicel M
- Badr A
- Badr MFM
- Badwi NM
- Badwi NM
- Badwy A
- Bahar S
- Baheeg M
- Bailey K
- Baillie K
- Baillie K
- Baird A
- Bakhaidar M
- Baki BE
- Bakr A
- Bakry HM
- Bala M
- Balalis D
- Baldacchino M
- Balducci G
- Balila RMH
- Balkan AZA
- Ballouhey Q
- Balmaceda R
- Balmaceda R
- Balmaceda R
- Balogun F
- Baltrunas R
- Baluch F
- Bamford R
- Bamicha A
- Bamicha A
- Banaitis VJ
- Bandi A
- Bandoh D
- Bani-Sadar A
- Banipal GS
- Baraka H
- Barakat SAE
- Barendegere V
- Barker T
- Barkolias C
- Barmayehvar B
- Barnabas GN
- Barnacle J
- Barneo L
- Barrionuevo Ojeda RR
- Barrios E
- Barrios E
- Barros De Castro Segundo LC
- Barroso de Lima CV
- Barry J
- Basilico S
- Basir ERM
- Bassem M
- Bassit KA
- Basso SMM
- Basson S
- Batt J
- Bayram S
- Beamon M
- Beasley W
- Beaton C
- Bedada AG
- Bediako-Bowan A
- Behar N
- Beisa V
- Beisa V
- Bekhet AH
- Bekhet NM
- Beleno AEM
- Belkouchi A
- Belli A
- Bello B
- Benammi S
- Benevento A
- Benevento A
- Benger M
- Bennai RM
- Benons N
- Bentounsi Z
- Benyaiche C
- Berti S
- Bertuello I
- Beuran M
- Beuran M
- Beyene R
- Bezerra Morais PA
- Bezzina M
- Bhang A
- Bhangu A
- Bhangu A
- Bhargava A
- Bharj IS
- Bhat S
- Bhatnagar A
- Bhattacharya S
- Bhopal KF
- Bhopal KF
- Bianco F
- Bigaran A
- Billy M
- Bin Adnan A
- Bin Hasnan M
- Bin Ismail MJ
- Bin Mahamood A
- Birindelli A
- Birring A
- Bisset C
- Bjorklund I
- Bjorklund I
- Blacker S
- Blackwell J
- Blanco R
- Blanco-Colino R
- Blencowe N
- Blencowe N
- Bliksoen M
- Blower E
- Bluelle R
- Blundell R
- Boakye-Yiadom K
- Boal M
- Bocchetti T
- Boddy A
- Bode C
- Bode C
- Bodur S
- Boereboom C
- Boggon A
- Boijsen M
- Bokhari S
- Bonavia K
- Bonavina L
- Bonavina L
- Bond-Smith G
- Bondin J
- Bondurri A
- Bondurri A
- Boni S
- Bonnard A
- Bonney W
- Borda Luque G
- Borda-Luque G
- Borda-Luque G
- Borg E
- Borg E
- Borg E
- Borin E
- Bortolasi L
- Bortolasi L
- Boshnaq M
- Botes S
- Bottini C
- Botto N
- Bouali O
- Bougard H
- Boukhal K
- Bowabsak A
- Bowe R
- Bowley D
- Bowling K
- Bowman C
- Boyce T
- Bradulskis S
- Bradulskis S
- Bratu M
- Bratu MR
- Bratu R-M
- Braungart S
- Bray LD
- Breaud J
- Breistrand M
- Breitenstein S
- Breslin R
- Brincat SD
- Broch A
- Brogden T
- Brown D
- Brown E
- Brown J
- Brown J
- Browning DRL
- Brunoni B
- Bsisu I
- Bucci L
- Bugaev N
- Bugeja R
- Buisson P
- Bukari M
- Bunting D
- Burger S
- Burmistrovas A
- Burns H
- Bustangi N
- Butt MT
- Cabala Chiong JA
- Cabala Chiong JA
- Cacurri A
- Cadogan DD
- Cahill R
- Cakaloglu HC
- Caliman C
- Callan R
- Camacho R
- Cameron B
- Camilleri GM
- Camilleri-Brennan J
- Camilleri-Brennan J
- Camilleri-Brennan JF
- Camilo Correa J
- Campagnaro T
- Canta Calua A
- Capito C
- Capleton P
- Carabott K
- Careta MC
- Carlucci M
- Carmela Lapitan M
- Carmona JM
- Carpio J
- Carrasco N
- Carreira J-A
- Carreiro De Freitas AV
- Cassar K
- Castro Mollo M
- Catani M
- Cautiero R
- Caydiid H
- Cecilia T
- Celik S
- Cengiz TB
- Cengiz Y
- Cengiz Y
- Cengiz Y
- Cengiz Y
- Ceriani C
- Cevik M
- Chabok A
- Chachulski W
- Chai C-A
- Chai FY
- Chambers A
- Chambers A
- Chan E
- Chan L
- Chan T-YK
- Chan XW
- Chan Z
- Chandrakumar C
- Chang K
- Chang KY-C
- Chapman A
- Chapman SJ
- Charles A
- Cheah AEZ
- Chen CY
- Chen KY
- Chen T-L
- Chenn R
- Cheong YJ
- Chetta N
- Cheung YHE
- Chew LS
- Chhabra S
- Chibuye C
- Chidambaram S
- Chiesa D
- Chilton G
- Chin PX
- Chin YR
- Chiu S
- Chiu S
- Chiu SMY
- Choi J
- Choi P
- Chong BFHK
- Chong CL
- Chong CL
- Chong CL
- Chong CS
- Chong H-Y
- Chong HY
- Choudhry A
- Chow CYN
- Chowdhury A
- Chowdhury D
- Chu K
- Chun A
- Chun T
- Chung KJ
- Chung S
- Ciccioli E
- Cirocchi R
- Ciubotaru C
- Claire R
- Clarissa A
- Clark DJ
- Clark T
- Clegg-Lampety J-N
- Clegg-Lamptey J-N
- Clement KD
- Clements JM
- Clerico G
- Clifford C
- Cloro LM
- Coasaca Huaraya R
- Coccolini F
- Coccolini F
- Coccolini F
- Coccolini F
- Cocker DM
- Cocorullo G
- Cohen DM
- Cohen F
- Cole S
- Coletta D
- Coletti M
- Colombani J-F
- Cona C
- Conci S
- Confalonieri G
- Conlon KC
- Connor K
- Connor K
- Contreras Merida SM
- Contreras Urquizu M
- Contreras Vergara AL
- Contreras E
- Coomber R
- Coompson CL
- Corbellini C
- Corbellino M
- Cornick J
- Coronel J
- Corro-Diaz Gonzalez S
- Corro-Diaz S
- Costa C
- Costa-Maia J
- Costa-Maia J
- Costas-Chavarri A
- Costas-Chavarri A
- Courboin E
- Court E
- Cox D
- Cox M
- Coyoy-Gaitan O
- Cragg J
- Craus-Miguel A
- Cross K
- Cruz DH
- Cruz H
- Cucumazzo S
- Cullen F
- Curletti G
- Currow C
- Currow C
- D'aguzan N
- D'Amours S
- D'amours SK
- D'cruz R
- D'Souza MS
- D'Souza R
- Da Silva LA
- Dabboor M
- Dabbour K
- Dabessa D
- Dablouk M
- Dablouk MO
- Dagoe E
- Dahy A
- Dainius E
- Dakubo J
- Dal Canto M
- Dalli J
- Dally C
- Dambrauskas Z
- Dambrauskas Z
- Dan I
- Danelli P
- Daniels I
- Daniyan M
- Danys D
- Dao W
- Daqeeq A
- Dar M
- Dar W
- Dardenne S
- Darweesh M
- Darwish AKZ
- Das A
- Das K
- Das S
- Dasari M
- Dashnyam E
- Dassah V
- Datta U
- Davenport R
- Davies J
- Davies R
- Davor A
- Dawnay G
- Dawood K
- Dawoud H
- Dayie M
- De Boni D
- De Bono P
- De Bono P
- De Franciscis S
- De Luca E
- De Marco P
- De Sousa AV
- Deal R
- Dean R
- Deane C
- Debrah S
- Deckelbaum DL
- Decker E
- Dedekind B
- Dedey F
- Deichsel F
- Del Basso C
- del Pilar Paucar A
- Delforge X
- Dell A
- Dempster E
- Denakpo M
- Denewar A
- Depalma N
- Deputy M
- Der Y
- Dervenis C
- Despotidis V
- Desta S
- Deutschmann P
- Devadasar GH
- Dharamshi HA
- Dhillon D
- Di Franco F
- Di Martino N
- Di Saverio S
- Di Saverio S
- Diab A
- Diaconescu B
- Diaconescu I-B
- Dias S
- Diaz Vico T
- Diaz-Jover P
- Diaz-Zorrilla C
- Dick L
- Dickfos M
- Dickson L
- Dijan E
- Dimech T
- Din F
- Dindyal S
- Dindyal S
- Dione Parreno-Sacdalan M
- Dissanayake T
- Djivoh F
- Domini E
- Domini E
- Donnelly P
- Donoghue D
- Dorani RMNR
- Dorisme A
- dos Santos DV
- Dossou F
- Doughan S
- Doughty J
- Dousset B
- Dragatas D
- Drake TM
- Drake TM
- Drake TM
- Driscoll A
- Drungilas M
- Du Plessis D
- du Plooy F
- Du Toit F
- Duane T
- Dubois A
- Duffy L
- Duhoranenayo D
- Duinhouwer L
- Dulskas A
- Dwydar A
- Ebdewi H
- Ebidy M
- Ebidy MM
- Ebrahim OS
- Eduard P
- Edwards J
- Edye M
- Eid MM
- Eisner L
- Ekow M
- El Ashal G
- El Dahab AA
- El Deen KN
- El Gendy A
- El Gendy NH
- El Halawany M
- El Jamassi A
- El Kashash A
- El Kholy A
- El Magd AA
- El Mesery S
- El Sayed GS
- El Sayed IM
- El Shoura Y
- El-badawy HA
- El-Dien KS
- El-Dien KS
- El-Din RA
- El-Din SA
- El-Gizawy E
- El-Hamouly AS
- El-Kashef H
- El-Latif NK
- El-Ma'doul AS
- El-Rabaa S
- El-Sagheer N
- El-Sawy A
- El-Sehily A
- El-Shahat NS
- El-Sheemy H
- El-Taher E
- Elabdin HZ
- Elashmawy M
- Elashry R
- Elazab A
- Elazayem AA
- Elazoul M
- Elbanby E
- Elbanby ES
- Elbatahgy A
- Elbe P
- Elbermawy M
- Elbisomy KH
- Eldafrawy M
- Eldamaty L
- Eldeeb AZ
- Eldeen EA
- Eldin MAB
- EldosoukyMohammed A
- Elebute O
- Elebute O
- Elena G
- Elfarargy A
- Elfeki H
- Elfeki H
- Elfiky M
- Elfil M
- Elfouly N
- Elfouly N
- Elfouly Y
- Elfouly Y
- Elgebaly A
- Elgendy AH
- Elgendy FI
- Elgheriany M
- Elhadad A
- Elhadary NM
- Elhadry S
- Elhalawany E
- Elhamouly S
- Elhelbawy MS
- Elhendawy A
- Elhendawy AOA
- Elhoseny G
- Elhusseiny AAE
- Elizabeth Lopez C
- Elkadsh I
- Elkady F
- Elkelany A
- Elkelany A
- Elkelany A
- Elkelany A
- Elkhadrawi M
- Elkhalek EA
- Elkholy A
- Elkholy SS
- Elkolaly SS
- Elkorashy AM
- Ellison Q
- Elmashala A
- Elmasry M
- Elmelegy R
- Elmihy S
- Elnagar A
- Elnajjar MA
- Elnemr AE
- Elrazek AA
- Elsabbagh N
- Elsameea AA
- Elsawahly DME
- Elsawy A
- Elsayed M
- Elsayed M
- Elsayed N
- Elsayed NAR
- Elsayed ZM
- Elsebaaye AO
- Elsehimy M
- Elsemelawy R
- Elshaar M
- Elshaer K
- Elshaer M
- Elshaer M
- Elshafay AE
- Elshami M
- Elshanwany S
- Elsharkawy AA
- Elsheikh S
- Elsherbiney S
- Elsherbiny AS
- Elsherif FA
- Elshobary M
- Elsiddig M
- Elsobky S
- Elsorogy DEAA
- Elwaey A
- Elwakil H
- Elwan A
- Elwan A
- Elwy E
- Elzahed N
- Elzayat I
- Elzayat M
- Elzayyat I
- Elzowawi F
- Emadeldin D
- Emadeldin H
- Emara E
- Emile S
- Eng C
- English W
- Esam A
- Escalante Salas MDC
- Espin-Basany E
- Espinoza F
- Essam A
- Essam AA
- Essam M
- Essoun S
- Esteban E
- Estee MM
- Estupinian S
- Etchill E
- Etchill E
- Etienne S
- Etman M
- Etwire V
- Evajelista CV
- Evans D
- Evans E
- Eysa A
- Eyssartier E
- Ezzat E
- Ezzat T
- Faboya O
- Faccincani R
- Fadel A
- Fahiem A
- Fahim M
- Fahmy MAB
- Fahy C
- Fairfield C
- Fairfield C
- Fairfield C
- Fairfield C
- Fakher R
- Falaschi F
- Falco N
- Falzon M
- Farag A
- Farag S
- Farah A
- Farahat MM
- Faraz A
- Fares M
- Farhad M
- Farhan-Alanie MMH
- Farhangmehr N
- Farinella E
- Farmakis K
- Farooq T
- Farouk SAM
- Farquharson A
- Farrugia A
- Farrugia A
- Faruq A
- Fathy AM
- Fattah AA
- Fatuga A
- Faturoti O
- Faturoti O
- Faure A
- Fautz T
- Favero A
- Fawzy A
- Feidantsis T
- Felipe CO
- Fergany A
- Fergusson SJ
- Fergusson SJ
- Fergusson SJ
- Fergusson SJ
- Fermani C
- Fermani CG
- Fernandes C
- Fernandez C
- Fernandez-Bueno F
- Fernandez-Vega L
- Ferousis C
- Ferrero E
- Fievet L
- Filatau A
- Findlay-Cooper K
- Firdouse M
- Firdouse M
- Firdouse M
- Firwana A
- Fitsum A
- Fitzgerald JE
- Fitzgerald JE
- Florez Farfan ES
- Foco M
- Fok CYJ
- Fontana T
- Foo CC
- Forlin L
- Forno W
- Fouad A
- Fouad D
- Fouad D
- Fourcade L
- Fowler AJ
- Fozard T
- Fozard T
- Frade F
- Fraga GP
- Francisco Roxas M
- Franco H
- Francois P
- Francois-Coridon H
- Francone E
- Freitas AV
- Frey D
- Frisk B
- Fuentes-Rivera L
- Fujii F
- Furqan MM
- Gaafar S
- Gaarder T
- Gad A
- Gad MO
- Gadelkarim M
- Gadhvi V
- Gado A
- Gaignard E
- Gaignard E
- Gaizauskas V
- Gala T
- Gala T
- Galiqi G
- Galleano R
- Gallo G
- Galloway S
- Galvez CP
- Gamal D
- Gamal E
- Gamal H
- Gamal S
- Gamaly E
- Gamil D
- Gan C
- Gan YY
- Gani MA
- Garaycochea O
- Garcia Bernardo C
- Garcia Florez LJ
- Garcia Septiem J
- Garcia Torres CP
- Garcia-Florez L
- Garland A
- Gash K
- Gash K
- Gash K
- Gastaldi P
- Gasteratos K
- Gaujoux S
- Gavagna L
- Gbessi DG
- Gemeah M
- Gemenetzis G
- Gemenetzis G
- George R
- Germanos S
- Germanos S
- Gerosa A
- Gerosa A
- Geuoshy A
- Ghaben A
- Ghandora N
- Ghanem A
- Ghanem E
- Ghanem S
- Ghanem S
- Ghannam M
- Gharib A
- Gharib A
- Ghazy AA
- Gheith A
- Ghetia M
- Ghetia M
- Ghonaim MA
- Ghoneem M
- Ghoneim O
- Giacci L
- Giardino FR
- Giavarini L
- Giglio MC
- Gilbert R
- Gilbert RW
- Giles J
- Gillespie M
- Gimzewska M
- Giraldo RSR
- Giuliani S
- Giuliani S
- Giuriato TF
- Gkiokas G
- Glasbey J
- Glasbey J
- Glasbey JC
- GlobalSurg Collaborative
- Glover TE
- Glover-Addy H
- Glynn M
- Gobin N
- Gobin N
- Goh CC
- Goh CC
- Goh W
- Gohar ME-SAM
- Gokani S
- Goldin E
- Golding D
- Gomaa A
- Gomah M
- Gonzales Montejo MS
- Gonzales Stuva JP
- Gonzalez M
- Goodstein M
- Gosling S
- Gosling SG
- Gouda A
- Gould L
- Gouldthorpe C
- Gouvas N
- Gouws J
- Graffeille V
- Graffieille V
- Gran M
- Grandinetti PP
- Grant A
- Grasset E
- Grasset E
- Grassi V
- Gratton R
- Gravante G
- Gravante G
- Gray D
- Grech N
- Green N
- Grella MG
- Gribauskaite J
- Griffiths E
- Griffiths E
- Griffiths M
- Grima T
- Grisin E
- Grizhja B
- Grobler DC
- Grosos C
- Grossart C
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- Publication venue
- Publication date
- 15/10/2018
- Field of study
Background The World Health Organization (WHO) Surgical Safety Checklist has fostered safe practice for 10 years, yet its place in emergency surgery has not been assessed on a global scale. The aim of this study was to evaluate reported checklist use in emergency settings and examine the relationship with perioperative mortality in patients who had emergency laparotomy. Methods In two multinational cohort studies, adults undergoing emergency laparotomy were compared with those having elective gastrointestinal surgery. Relationships between reported checklist use and mortality were determined using multivariable logistic regression and bootstrapped simulation. Results Of 12 296 patients included from 76 countries, 4843 underwent emergency laparotomy. After adjusting for patient and disease factors, checklist use before emergency laparotomy was more common in countries with a high Human Development Index (HDI) (2455 of 2741, 89.6 per cent) compared with that in countries with a middle (753 of 1242, 60.6 per cent; odds ratio (OR) 0.17, 95 per cent c.i. 0.14 to 0.21, P <0001) or low (363 of 860, 422 per cent; OR 008, 007 to 010, P <0.001) HDI. Checklist use was less common in elective surgery than for emergency laparotomy in high-HDI countries (risk difference -94 (95 per cent c.i. -11.9 to -6.9) per cent; P <0001), but the relationship was reversed in low-HDI countries (+121 (+7.0 to +173) per cent; P <0001). In multivariable models, checklist use was associated with a lower 30-day perioperative mortality (OR 0.60, 0.50 to 073; P <0.001). The greatest absolute benefit was seen for emergency surgery in low- and middle-HDI countries. Conclusion Checklist use in emergency laparotomy was associated with a significantly lower perioperative mortality rate. Checklist use in low-HDI countries was half that in high-HDI countries.Peer reviewe
Particle identification in ALICE : a Bayesian approach
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- Heckel ST
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- Hippolyte B
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- Humanic TJ
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- Kalweit A
- Kamin J
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- Kaplin V
- Kar S
- Karavichev O
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- Kebschull U
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- Keijdener DLD
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- Kisel I
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- Klewin S
- Kluge A
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- Kofarago M
- Kollegger T
- Kolojvari A
- Kondratiev V
- Kondratyeva N
- Kondratyuk E
- Konevskikh A
- Kopcik M
- Kostarakis P
- Kour M
- Kouzinopoulos C
- Kovalenko O
- Kovalenko V
- Kowalski M
- Kralik I
- Kravcakova A
- Krivda M
- Krizek F
- Kryshen E
- Krzewicki M
- Kubera AM
- Kucera V
- Kuhn C
- Kuijer PG
- Kumar A
- Kumar J
- Kumar L
- Kumar S
- Kurashvili P
- Kurepin A
- Kurepin AB
- Kuryakin A
- Kweon MJ
- Kwon Y
- La Pointe SL
- La Rocca P
- Ladron de Guevara P
- Lagana Fernandes C
- Lakomov I
- Langoy R
- Lara C
- Lara CEP
- Lardeux A
- Lattuca A
- Laudi E
- Lea R
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- Lee GR
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- Leogrande E
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- Lezama EP
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- Lindenstruth V
- Lippmann C
- Lisa MA
- Ljunggren HM
- Lodato DF
- Loenne PI
- Loginov V
- Loizides C
- Lopez X
- Lowe A
- Luettig P
- Lunardon M
- Luparello G
- Lutz TH
- Maevskaya A
- Mager M
- Mahajan S
- Mahmood SM
- Maire A
- Majka RD
- Mal'Kevich D
- Malaev M
- Maldonado Cervantes I
- Malinina L
- Malzacher P
- Mamonov A
- Manko V
- Manso AR
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- Manzari V
- Marchisone M
- Mares J
- Margagliotti GV
- Margotti A
- Margutti J
- Marin A
- Markert C
- Marquard M
- Martin NA
- Martinengo P
- Martinez MI
- Mas A
- Masciocchi S
- Masera M
- Masoni A
- Mastroserio A
- Matyja A
- Mayer C
- Mazer J
- Mazzoni MA
- Mcdonald D
- Meddi F
- Meethaleveedu GK
- Melikyan Y
- Menchaca-Rocha A
- Meninno E
- Meres M
- Miake Y
- Mieskolainen MM
- Mikhaylov K
- Milano L
- Milosevic J
- Mischke A
- Mishra AN
- Miskowiec D
- Mitra J
- Mitu CM
- Mohammadi N
- Mohanty B
- Molnar L
- Montano Zetina L
- Montero AJR
- Montes E
- Monzon IL
- Morales YC
- Moreno LAP
- Moretto S
- Morreale A
- Morsch A
- Muccifora V
- Mudnic E
- Muehlheim D
- Muhuri S
- Mukherjee M
- Mulligan JD
- Munhoz MG
- Munzer RH
- Murakami H
- Murray S
- Musa L
- Musinsky J
- Naik B
- Nair R
- Nandi BK
- Nania R
- Nappi E
- Naru MU
- Natal da Luz H
- Nattrass C
- Navarro SR
- Nayak K
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- Nazarenko S
- Nedosekin A
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- Nicassio M
- Niculescu M
- Niedziela J
- Nielsen BS
- Nikolaev S
- Nikulin S
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- Nomokonov P
- Nooren G
- Noris JCC
- Norman J
- Nyanin A
- Nystrand J
- Oeschler H
- Oh S
- Oh SK
- Ohlson A
- Okatan A
- Okubo T
- Olah L
- Oleniacz J
- Oliveira Da Silva AC
- Oliver MH
- Onderwaater J
- Oppedisano C
- Orava R
- Oravec M
- Ortiz Velasquez A
- Oskarsson A
- Otwinowski J
- Oyama K
- Ozdemir M
- Pachmayer Y
- Pagano D
- Pagano P
- Paic G
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- Palomo LV
- Pan J
- Pandey AK
- Papikyan V
- Pappalardo GS
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- Porteboeuf-Houssais S
- Porter J
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- Prasad SK
- Preghenella R
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- Pruneau CA
- Pshenichnov I
- Puccio M
- Puddu G
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- Punin V
- Putschke J
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- Raesaenen SS
- Raha S
- Rajput S
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- Rakotozafindrabe A
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- Rossi A
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- Ryabov Y
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- Sadhu S
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- Senyukov S
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- Sumowidagdo S
- Szabo A
- Szanto de Toledo A
- Szarka I
- Szczepankiewicz A
- Szymanski M
- Tabassam U
- Takahashi J
- Tambave GJ
- Tanaka N
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- Tariq M
- Tarzila MG
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- Utrobicic A
- Uysal AK
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- Vislavicius V
- Viyogi YP
- Vodopyanov A
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- Voloshin K
- Voloshin SA
- Volpe G
- von Haller B
- Vorobyev I
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- Vrlakova J
- Vulpescu B
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- Zaborowska A
- Zaccolo V
- Zaman A
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- Zanoli HJC
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- Zgura IS
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- Zichichi A
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- Publication venue
- Publication date
- 01/01/2016
- Field of study
Peer reviewe
- …