Magnetic Nanotherapy by Magnetosensitive Nanocomplexes with Different Magnetic Properties of the Walker 256 Carcinosarcoma

The magnetic nanocomplex (MNC) comprised of Fe3O4 nanoparticles (NP) and doxorubicin (DOXO) with a saturation magnetic magnetic moment m3 = 10.5 emu/g during magnetic nanotherapy initiated greater antitumor effect than MNC with m3 = 8.55 emu/g. After treatment of Walker 256 tumor the concentration of iron ions in the blood serum of animals with tumor increased and did not depend on the magnetic properties of MNC

Chiral And Parity Anomalies At Finite Temperature And Density

Two closely related topological phenomena are studied at finite density and temperature. These are chiral anomaly and Chern-Simons term. By using different methods it is shown that $\mu^2 = m^2$ is the crucial point for Chern-Simons at zero temperature. So when $\mu^2 < m^2$ $\mu$--influence disappears and we get the usual Chern-Simons term. On the other hand when $\mu^2 > m^2$ the Chern-Simons term vanishes because of non-zero density of background fermions. It is occurs that the chiral anomaly doesn't depend on density and temperature. The connection between parity anomalous Chern-Simons and chiral anomaly is generalized on finite density. These results hold in any dimension as in abelian, so as in nonabelian cases

Comparative characteristics of human stem cells

Stem cell therapy is one of the most perspective methods of clinical medicine; SC-containing products are actively investigated in clinical trials, while some of them are already officially approved for treatment in many countries worldwide. The purpose of this review is to perform comparative analysis of stem cell types, methods of their procurement and perspectives of their employment. Stem cells (SCs) could be divided into groups according to the age of the donor organism. Embryonic SCs are isolated from blastocyst, obtained as a result of extracorporeal fertilization, cloning, semicloning or parthenogenesis (androgenetic and gynogenetic SCs). Fetal SCs could be isolated from embryonic and fetal tissues before the birth or from miscarriages and abortion material (including ectopic pregnancy). Among fetal there is and especial group of perinatal extraembryonic SCs which are obtained from extraembryonic organs (umbilical cord, amnion, placenta) after the birth; among them hematopoietic, mesenchymal, epithelial and decidual cells are distinguished. Adult (somatic, tissue specific) SCs could be isolated from different tissues and organs of adult organism throughout the life; their properties depend on the place of their localization and age of the donor. Additionally, SCs could be created artificially from mature cells by modification of gene expression; they are united in the group of induced pluripotent SCs. Every group of SCs is not homogenous and has its advances and drawbacks are analyzed in this review. Also, application of exosomes, microvesicles and apoptotic bodies produced by stem cells as an alternative of cellular therapy is considered

Analysis of the krok1 and histology subtests dynamics of students of Dnipropetrovsk medical academy

Оbjective control of the level of knowledge in medical universities is the basis for guaranteeing the quality of education. There are a lot of examples of universal systems designed to evaluate medical students in different countries, including USMLE, IFOM and others; particularly in Ukraine Krok&nbsp;1 licensed exam is conducted since 2005. Results of Krok&nbsp;1 are also used for ranking medical universities at the national level. The purpose of our work was to conduct a comparative analysis of the results of the licensing exam Krok&nbsp;1, in particular, a histology subtest, among students of specialties 221 “Dentistry” and 222 “Medicine” and different languages of education (Ukrainian, Russian, English) in Dnipropetrovsk medical academy. We have revealed that all the analyzed contingents of students (DMA as well as Ukrainian) in the majority of observation periods from 2014 to 2019 had lower average results on histology compared to average Krok&nbsp;1 results. This could be explained by low quota of histological tests for students of specialty 222 “Medicine” which is 4-6%, and absence of the threshold level for doing each particular subject. These conditions do not motivate students of the third course to recollect a complicated discipline that ended more than a year ago. Another problem is in the content of anchor questions in Krok&nbsp;1 booklets: the number of such questions are distributed unevenly among booklets of different years and different languages of study. As a result, students with different languages of study are put in unequal conditions. In addition, the variation in the number of anchor tests from year to year, the lack of a declared quota of such tests disorients students and makes it difficult to develop algorithms for preparing for Krok&nbsp;1

Leading order determination of the gluon polarisation from DIS events with high-p_T hadron pairs

We present a determination of the gluon polarisation Delta g/g in the nucleon, based on the longitudinal double-spin asymmetry of DIS events with a pair of large transverse-momentum hadrons in the final state. The data were obtained by the COMPASS experiment at CERN using a 160 GeV/c polarised muon beam scattering off a polarised ^6LiD target. The gluon polarisation is evaluated by a Neural Network approach for three intervals of the gluon momentum fraction x_g covering the range 0.04 < x_g < 0.27. The values obtained at leading order in QCD do not show any significant dependence on x_g. Their average is Delta g/g = 0.125 +/- 0.060 (stat.) +/- 0.063 (syst.) at x_g=0.09 and a scale of mu^2 = 3 (GeV/c)^2.Comment: 13 pages, 6 figures and 3 table

The Spin-dependent Structure Function of the Proton g_1^p and a Test of the Bjorken Sum Rule

The inclusive double-spin asymmetry, A_1^p, has been measured at COMPASS in deepinelastic polarised muon scattering off a large polarised NH3 target. The data, collected in the year 2007, cover the range Q2 > 1 (GeV/c)^2, 0.004 < x < 0.7 and improve the statistical precision of g_1^p(x) by a factor of two in the region x < 0.02. The new proton asymmetries are combined with those previously published for the deuteron to extract the non-singlet spin-dependent structure function g_1^NS(x,Q2). The isovector quark density, Delta_q_3(x,Q2), is evaluated from a NLO QCD fit of g_1^NS. The first moment of Delta_q3 is in good agreement with the value predicted by the Bjorken sum rule and corresponds to a ratio of the axial and vector coupling constants g_A/g_V = 1.28+-0.07(stat)+-0.10(syst).Comment: 12 pages, 5 figure

Measurement of the Collins and Sivers asymmetries on transversely polarised protons

The Collins and Sivers asymmetries for charged hadrons produced in deeply inelastic scattering on transversely polarised protons have been extracted from the data collected in 2007 with the CERN SPS muon beam tuned at 160 GeV/c. At large values of the Bjorken x variable non-zero Collins asymmetries are observed both for positive and negative hadrons while the Sivers asymmetry for positive hadrons is slightly positive over almost all the measured x range. These results nicely support the present theoretical interpretation of these asymmetries, in terms of leading-twist quark distribution and fragmentation functions.Comment: 9 Pages, 5 figure

Measurement of the Spin Structure of the Deuteron in the DIS Region

We present a new measurement of the longitudinal spin asymmetry A_1^d and the spin-dependent structure function g_1^d of the deuteron in the range 1 GeV^2 < Q^2 < 100 GeV^2 and 0.004< x <0.7. The data were obtained by the COMPASS experiment at CERN using a 160 GeV polarised muon beam and a large polarised 6-LiD target. The results are in agreement with those from previous experiments and improve considerably the statistical accuracy in the region 0.004 < x < 0.03.Comment: 10 pages, 6 figures, subm. to PLB, revised: author list, Fig. 4, details adde

Quark helicity distributions from longitudinal spin asymmetries in muon-proton and muon-deuteron scattering

Double-spin asymmetries for production of charged pions and kaons in semi-inclusive deep-inelastic muon scattering have been measured by the COMPASS experiment at CERN. The data, obtained by scattering a 160 GeV muon beam off a longitudinally polarised NH_3 target, cover a range of the Bjorken variable x between 0.004 and 0.7. A leading order evaluation of the helicity distributions for the three lightest quarks and antiquark flavours derived from these asymmetries and from our previous deuteron data is presented. The resulting values of the sea quark distributions are small and do not show any sizable dependence on x in the range of the measurements. No significant difference is observed between the strange and antistrange helicity distributions, both compatible with zero. The integrated value of the flavour asymmetry of the helicity distribution of the light-quark sea, \Delta u-bar - \Delta d-bar, is found to be slightly positive, about 1.5 standard deviations away from zero.Comment: 13 pages, 5 figure

The COMPASS Experiment at CERN

The COMPASS experiment makes use of the CERN SPS high-intensitymuon and hadron beams for the investigation of the nucleon spin structure and the spectroscopy of hadrons. One or more outgoing particles are detected in coincidence with the incoming muon or hadron. A large polarized target inside a superconducting solenoid is used for the measurements with the muon beam. Outgoing particles are detected by a two-stage, large angle and large momentum range spectrometer. The setup is built using several types of tracking detectors, according to the expected incident rate, required space resolution and the solid angle to be covered. Particle identification is achieved using a RICH counter and both hadron and electromagnetic calorimeters. The setup has been successfully operated from 2002 onwards using a muon beam. Data with a hadron beam were also collected in 2004. This article describes the main features and performances of the spectrometer in 2004; a short summary of the 2006 upgrade is also given.Comment: 84 papes, 74 figure