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Mortality and pulmonary complications in patients undergoing surgery with perioperative sars-cov-2 infection: An international cohort study

Author: Aaraj M. A.
Abate E.
Abbott S. J.
Abbott T. E. F.
Abdalaziz H.
Abdalla M. O.
Abdelaal A. S.
Abdelkarim M.
Abdou H.
Aboelkassem-Ibrahim A.
Abuown A.
Acebes-Garcia F.
Acharya M.
Adamina M.
Addae-Boateng E.
Aftab R.
Aguilar J.
Aherne T. M.
Ahmed Y.
Aitken E.
Al-Azzawi M.
Al-Embideen S.
Al-Masri M.
Al-Najjar H.
Al-Sukaini A.
Alam R.
Alanbuki A.
Ali I. A. M.
Ali O. M.
Aliyeva Z.
Aljanadi F.
Almaadany F. S.
Almasri M.
Almeida A. C.
Alonso-Ortuno P.
Alrahawy M. M.
Alser O.
Altintoprak F.
Alvarez M. R.
Ambler G. K.
Amira G.
Amjad R.
Anania G.
Andabaka T.
Andreani S. M.
Angelou D.
Annamalai S.
Annessi V.
Anthoney J.
Antonanzas L. L.
Anwar S.
Anwer M.
Aoun S. G.
Aragon-Chamizo J.
Archer J. E.
Ardito A.
Arigoni M.
Armao T.
Arminio A.
Armstrong L.
Arnaud A. P.
Asaad P.
Ashcroft J.
Ashmore C.
Ashoush F. M.
Asqalan A.
Asti E.
Aubry E.
Avellana R. B.
Ayeni F. A.
Ayorinde J. O.
Aytac E.
Ayuso-Herrera E.
Babu B. H.
Baeza M.
Baig M. M.
Bajomo O. M.
Baker M. P.
Baker O. J.
Bakmaz B.
Bakri N. A. C.
Baldi C.
Baldini E.
Baldo S.
Baldwin A. J.
Ballabio M.
Baloyiannis I.
Baltazar G.
Bambina F.
Ban V. S.
Bandiera A.
Bankhead-Kendall B. K.
Barmasse R.
Barmpagianni C.
Baron R. D.
Baronio G.
Barra F.
Barranquero A. G.
Barry C. P.
Bartolomeo A. D.
Bartsch A. -M.
Basgaran A.
Basha A.
Bashkirova V.
Bass G. A.
Bastazza M.
Bath M. F.
Batjer H. H.
Baumber R.
Bauset J. C. C.
Beak P.
Beamish A. J.
Belcher E.
Belgaumkar A. P.
Belvedere A.
Bence M. N.
Benitez-Linero I.
Bergeat D.
Bernal-Sprekelsen J. C.
Bernasconi M.
Bhalla A.
Bhama A. R.
Bhangu A.
Bhavaraju A. V.
Bhutiani N.
Bianco F.
Biffl W. L.
Bisagni P.
Blake I.
Blazer D. G.
Blazquez-Martin A.
Blundell C. M.
Boal M.
Boddy A. P.
Bonavina G.
Bonavina L.
Bond-Smith G.
Booth K.
Borges F.
Borghi F.
Borgstein A. B. J.
Bosanquet D. C.
Bosch K. D.
Bouhuwaish A. E. M.
Bourke G.
Boyle E.
Bozkurt M. A.
Brachini G.
Brain J.
Brathwaite C. E. M.
Breckles L.
Breen K. A.
Bretagnol F.
Brianza C.
Brixton G.
Brown A. K.
Brown B. C.
Brown O. D.
Bruzzaniti P.
Bueno-Canones A. D.
Bueser T.
Bulugma M. R.
Burke J. R.
Burnside N.
Byrne M. H. V.
Caballero A.
Cagigal-Ortega E. P.
Calcerrada-Alises E.
Callahan M.
Callcut R. A.
Camarero E.
Campagnaro T.
Campanelli M.
Candiani M.
Candido F. D.
Cannoletta M.
Canova M. E.
Cantalejo-Diaz M.
Cao H.
Capelli P.
Capitan-Morales L. -C.
Capizzi V.
Carcano G.
Carissimi F.
Carlini M.
Carlos W. J.
Carlucci M.
Carmichael H.
Carrasco M.
Carrillo M.
Caruana E. J.
Carvello M.
Casati M.
Castoro C.
Catalan V.
Cato L. D.
Catton A. B.
Cavaleiro S.
Cellerino P.
Centinaio G.
Ceretti A. P.
Cernei C.
Cerro C.
Cervellera M.
Chaar M. K. A.
Chamberlain S.
Chan J.
Chang G.
Chase T. J. G.
Chebaro A.
Chen D.
Chetty G.
Chia Z.
Chiappini A.
Chiarugi M.
Chidambaram S.
Chiozza M.
Cholewa H.
Chong C.
Choolani-Bhojwani E.
Chowdhury A. H.
Chrastek D.
Chui K.
Chung C.
Chung E. A.
Cicerchia P. M.
Cirillo B.
Citterio D.
Clermidi P.
Clough E. C. S.
Coccolini F.
Coleman N. L.
Colletti G.
Collins C. G.
Collins M. L.
Colonna E. T.
Comini L. V.
Compagnoni B.
Confalonieri M.
Connelly T. M.
Connolly H.
Conso C.
Conti L.
Cooper Z.
Corbellini C.
Corral J.
Costa M.
Costa P. M.
Costanzi A.
Cotsoglou C.
Coughlin P. A.
Cozza V.
Cruzado L. F. -G.
Cuadrado M. B.
Cuming T.
Curtis M.
Cuschieri J.
D'Agruma M.
D'Andrea G.
Daliya P.
Dare O.
Darko E.
Dass D.
Davidson B. R.
Davidson G. H.
Davies E. J.
Davies R. J.
Davis N. F.
Day A.
De Andres-Asenjo B.
De Heredia J. B.
De Lacy F. B.
De Miguel-Ardevines M. -C.
De Souza A. C.
De Virgilio A.
De Vries J. -P. P. M.
Dean B. J. F.
Dean H.
Dehal A.
Dehart D.
Delgado M. G. -C.
Delgado-Oliver E.
Denning M.
Desender L.
Dester S.
Di Chiara F.
Di Saverio S.
Diaz C. J. G.
Diaz J. J.
Diaz-Garcia A.
Diaz-Pena P.
Dickson K. E.
Diez-Alonso M. M.
Dixon J. R.
Doe M. J.
Dousset B.
Doussot A.
Drake F. T.
Duchateau N.
Duff S.
Duffy J. P.
Dunne D. F. J.
Dunne N. J. M.
Dunning J.
Dunstan M.
Duran-Munoz-Cruzado V. M.
Durst A. Z. E.
Dziakova J.
Eardley N. J.
Edwards J. G.
Egan B.
Egan R.
El-Ali A.
Elfallal A. H.
Elfeki H.
Elfiky M. M. A.
Eljareh M.
Elkadi H. H.
Elkady R.
Elkhafeefi F.
Elliott J. A.
Elmore U.
Elmoslemany T.
Emile S. H.
Emmerson O.
Emslie K. M.
Endorf F. W.
Enemosah I.
Engel J. L.
English C.
English W.
Enjuto D. T.
Erridge S.
Escartin J.
Estaire-Gomez M.
Etchill E. W.
Evans J.
Evans L.
Exley R.
Fabbri N.
Fahey B. A.
Falco G.
Familiari P.
Fancellu A.
Faria C. S.
Farrell T.
Fehervari M.
Fell A.
Feo C. V.
Ferguson H. J. M.
Fernandez A. G.
Fernandez A. J.
Fernandez A. V.
Fernandez B. D.
Fernandez-Camunas A.
Fernandez-Marin R.
Fernandez-Martinez M.
Fernandez-Pacheco B. C.
Ferrara F.
Ferrari G.
Ferrero S.
Findlay L.
Fiore M.
Fiori E.
Flatman M.
Flindall I.
Flor B.
Fonsi G. B.
Font R. F.
Fontana T.
Ford D.
Forlani S.
Fowler A. L.
Franco G. D.
Francone E.
Frattaruolo C.
Fretwell K. R.
Frio F.
Fructuoso L. S.
Fusai G. K.
Gagliano A.
Gagliardi F.
Gahunia S.
Gaino F.
Gala T.
Galfrascoli E.
Galimberti L.
Gallagher P.
Galleano R.
Gallo G.
Galocha J. L. G.
Galvan-Perez A.
Gammeri E.
Ganau M.
Garces-Garcia R.
Garcia M. H.
Garcia-Urena M. A.
Gardner A.
Garulli G.
Gascon-Ferrer I.
Gattolin A.
Gaujoux S.
Gautam M.
Gentilli S.
Georgiades F.
Gerogiannis I.
Ghanbari A.
Gheldere C. A. D.
Giacometti M.
Giblin A. -V.
Gilbert C.
Gill C. K.
Gimenez C.
Giorgakis E.
Gipponi M.
Gisbertz S. S.
Giudice R. D.
Giuffrida M. C.
Giuseppe M. D.
Glen P.
Goatly G.
Gobatti D.
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Gomez M.
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Gomez-Rosado J. -C.
Gonullu E.
Gonzalez J. S.
Gonzalez-Gonzalez E.
Gordini L.
Gracia I.
Gracia-Roche C.
Granieri S.
Green S.
Gregg A.
Griffiths E. A.
Grivon M.
Grove T.
Guaglio M.
Guaitoli E.
Guariglia C. A.
Guglielmi A.
Guha S.
Gustavino C.
Habeeb A.
Hagger R.
Hainsworth A. J.
Hakmi H.
Halkias C.
Hall B. J.
Hall C.
Hall J. R. W.
Hammond J. S.
Hampton M.
Handa S.
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Haq I.
Haqqani M. H.
Harky A.
Harries R.
Harrison J.
Hasan R.
Hawari M.
Hawkin P.
Hazelton J. P.
Hebblethwaite B.
Henegouwen M. I. V. B.
Henriques S.
Hernandez-Juara P.
Herrero-Lopez M.
Hervieux E.
Heyd B.
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Hing C. B.
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Hogan A.
Holbrook C. M.
Holme T. J.
Holzle F.
Hopkins J. C.
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Hossain F. S.
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Houston R.
Hudson V. E.
Hughes J. L.
Hurt L.
Hwang E. S.
Iacob G.
Iannone I.
Ibrahim M. A. H.
Ibrahim S.
Iovino D.
Irvine E.
Isolani S. M.
Jafarova S.
Jamil T.
Jara P. G.
Jayaraju U.
Jeganathan R.
Jenkinson M. D.
Jenner E.
Jenny H. E.
Jeyaretna D. S.
Jiao L. R.
Jimenez-Higuera E.
Jimeno J.
Johnstone J. R.
Jones A. P.
Jones G. P.
Jones M.
Jones R. P.
Jonker P. K. C.
Jonsson M. L.
Joyce D. P.
Judkins N.
Kaafarani H. M.
Kalavrezos N.
Kalidindi V.
Kalkat M.
Kalkwarf K. J.
Kamal M.
Kamphues C.
Kang C.
Kara Y.
Karam E.
Karim A.
Kashora F.
Kassas M. E.
Kaushal M. V.
Kavanagh D. O.
Kearney D.
Khajuria A.
Khalefa M. A.
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Khan J. S.
Khan U.
Kinnaman G.
Kinross J.
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Kisiel A. P.
Kler A.
Klimopoulos S.
Kocatas A.
Kolias A.
Konigsrainer A.
Konsten J.
Kontovounisios C.
Kourdouli A.
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Kristinsson S.
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Kudsk-Iversen S.
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Lin D. J.
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Liu H. H.
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Lo T.
Loffler M. W.
Lombardi C. P. (ORCID:0000-0001-8910-6693)
Lomiento D.
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Lostoridis E.
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Lowy-Benoliel A.
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Marra A. A.
Marrano E.
Marsh C. L.
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Martin G.
Martin R. C. G.
Martin-Albo L.
Martin-Roman L.
Martinelli F.
Martinez-Depaz F.
Martinez-German A.
Martinez-Pinedo C.
Martins R.
Marwan H.
Marzi F.
Mashbari H. N.
Mateo-Sierra O.
Mathieu P.
Matute-Najarro M. -S.
Maw A.
Mazzaferro V.
McCanny A.
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Mele S.
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Toro M. D. D.
Torquati A.
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Torres A. J.
Torzilli G.
Totty J.
Tourountzi P.
Tousidonis M.
Townsend C.
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Valdes-Hernandez J.
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Van Der Plas W. Y.
Van Heinsbergen M.
Vashisht R.
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Velmahos G. C.
Velopulos C. G.
Venkatesan G. S.
Venn M. L.
Vergari R.
Vescio G.
Vieira P.
Vijay V.
Vimalachandran D.
Violante T.
Viswanath Y. K. S.
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Volpe A.
Vovola F.
Vulliamy P.
Wade R. G.
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Wallwork K.
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Waseem S.
Weaver H.
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Williams M.
Winnand P.
Winter S. C.
Wong K.
Worku D.
Wormald J. C. R.
Wright F. L.
Xyda S. E.
Yalamanchili S.
Yershov D.
Yildiz A.
Young A. L.
Young R.
Youssef M. M. G.
Yousuf F. B.
Youzouri H. E.
Yurttas C.
Zadegan F.
Zafar N.
Zakaria R.
Zambon M.
Zanini N. C.
Zappa M. A.
Zarate A.
Zerbib P.
Zmora O.
Zonta S.
Publication venue: 'Elsevier BV'
Publication date: 01/01/2020
Field of study

Background The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on postoperative recovery needs to be understood to inform clinical decision making during and after the COVID-19 pandemic. This study reports 30-day mortality and pulmonary complication rates in patients with perioperative SARS-CoV-2 infection. Methods This international, multicentre, cohort study at 235 hospitals in 24 countries included all patients undergoing surgery who had SARS-CoV-2 infection confirmed within 7 days before or 30 days after surgery. The primary outcome measure was 30-day postoperative mortality and was assessed in all enrolled patients. The main secondary outcome measure was pulmonary complications, defined as pneumonia, acute respiratory distress syndrome, or unexpected postoperative ventilation. Findings This analysis includes 1128 patients who had surgery between Jan 1 and March 31, 2020, of whom 835 (740%) had emergency surgery and 280 (248%) had elective surgery. SARS-CoV-2 infection was confirmed preoperatively in 294 (261%) patients. 30-day mortality was 238% (268 of 1128). Pulmonary complications occurred in 577 (512%) of 1128 patients; 30-day mortality in these patients was 380% (219 of 577), accounting for 817% (219 of 268) of all deaths. In adjusted analyses, 30-day mortality was associated with male sex (odds ratio 175 [95% CI 128-240], p<00001), age 70 years or older versus younger than 70 years (230 [165-322], p<00001), American Society of Anesthesiologists grades 3-5 versus grades 1-2 (235 [157-353], p<00001), malignant versus benign or obstetric diagnosis (155 [101-239], p=0046), emergency versus elective surgery (167 [106-263], p=0026), and major versus minor surgery (152 [101-231], p=0047). Interpretation Postoperative pulmonary complications occur in half of patients with perioperative SARS-CoV-2 infection and are associated with high mortality. Thresholds for surgery during the COVID-19 pandemic should be higher than during normal practice, particularly in men aged 70 years and older. Consideration should be given for postponing non-urgent procedures and promoting non-operative treatment to delay or avoid the need for surgery. Funding National Institute for Health Research (NIHR), Association of Coloproctology of Great Britain and Ireland, Bowel and Cancer Research, Bowel Disease Research Foundation, Association of Upper Gastrointestinal Surgeons, British Association of Surgical Oncology, British Gynaecological Cancer Society, European Society of Coloproctology, NIHR Academy, Sarcoma UK, Vascular Society for Great Britain and Ireland, and Yorkshire Cancer Research

PubliCatt

Elective cancer surgery in COVID-19-free surgical pathways during the SARS-CoV-2 pandemic: An international, multicenter, comparative cohort study

Author: Aawsaj Y.
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Abad-Motos A.
Abate E.
Abatini C.
Abbadessa F.
Abbas A. M.
Abbassi-Ghadi N.
Abbott D.
Abbott T.
Abd Elazeem H. A. S.
Abdalla M.
Abdallah M.
Abdel Al S.
Abdel Jalil R.
Abdeldayem H.
Abdelkader Salama I.
Abdelkarem M. M.
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Abdelmajeed A.
Abdelrahman A.
Abdelrahman S.
Abdelsamed A.
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Abellan M.
Aboelkassem Ibrahim A.
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Abou Chaar M. K.
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Aboulkassem H.
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Abu Za'nouneh F. J.
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Publication venue: 'American Society of Clinical Oncology (ASCO)'
Publication date: 01/01/2021
Field of study

PURPOSE As cancer surgery restarts after the first COVID-19 wave, health care providers urgently require data to determine where elective surgery is best performed. This study aimed to determine whether COVID-19–free surgical pathways were associated with lower postoperative pulmonary complication rates compared with hospitals with no defined pathway. PATIENTS AND METHODS This international, multicenter cohort study included patients who underwent elective surgery for 10 solid cancer types without preoperative suspicion of SARS-CoV-2. Participating hospitals included patients from local emergence of SARS-CoV-2 until April 19, 2020. At the time of surgery, hospitals were defined as having a COVID-19–free surgical pathway (complete segregation of the operating theater, critical care, and inpatient ward areas) or no defined pathway (incomplete or no segregation, areas shared with patients with COVID-19). The primary outcome was 30-day postoperative pulmonary complications (pneumonia, acute respiratory distress syndrome, unexpected ventilation). RESULTS Of 9,171 patients from 447 hospitals in 55 countries, 2,481 were operated on in COVID-19–free surgical pathways. Patients who underwent surgery within COVID-19–free surgical pathways were younger with fewer comorbidities than those in hospitals with no defined pathway but with similar proportions of major surgery. After adjustment, pulmonary complication rates were lower with COVID-19–free surgical pathways (2.2% v 4.9%; adjusted odds ratio [aOR], 0.62; 95% CI, 0.44 to 0.86). This was consistent in sensitivity analyses for low-risk patients (American Society of Anesthesiologists grade 1/2), propensity score–matched models, and patients with negative SARS-CoV-2 preoperative tests. The postoperative SARS-CoV-2 infection rate was also lower in COVID-19–free surgical pathways (2.1% v 3.6%; aOR, 0.53; 95% CI, 0.36 to 0.76). CONCLUSION Within available resources, dedicated COVID-19–free surgical pathways should be established to provide safe elective cancer surgery during current and before future SARS-CoV-2 outbreaks

Archivio istituzionale della Ricerca - Università degli Studi di Parma

Elective Cancer Surgery in COVID-19-Free Surgical Pathways During the SARS-CoV-2 Pandemic: An International, Multicenter, Comparative Cohort Study.

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Abad Gurumeta A.
Abad-Motos A.
Abate E.
Abatini C.
Abbadessa F.
Abbas A. M.
Abbassi-Ghadi N.
Abbott D.
Abbott T.
Abd Elazeem H. A. S.
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Aboelkassem Ibrahim A.
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Uyanik M. S.
Uzunoglu F. G.
Vaccarella G.
Vahtsevanos K.
Valbuena Jabares V.
Valdes-Hernandez J.
Valente Da Costa A.
Valero R.
Valero Soriano M.
Vallance A.
Valle Rubio A.
Valtzoglou V.
Valverde S.
Van Den Eynde J.
Van Den Eynde R.
Van Duijvendijk P.
Van Heinsbergen M.
Van Houdt W.
Van Wyngaard T.
Vanounou T.
Varazzani A.
Vargas L.
Varley I.
Varma M.
Vasljevic J.
Vassiliu P.
Vatansever D.
Vatish J.
Vatish M.
Vaz O. P.
Vaz Pereira R.
Vaz S.
Vazquez Fernandez A.
Veiga D.
Velagapudi S.
Velchuru V.
Velickovic D.
Velidedeoglu M.
Venetis G.
Venn M. L.
Venskutonis D.
Vera Mansilla C.
Verberne C.
Vergari R.
Vernon L.
Vervoort D.
Vescio G.
Vezakis A.
Vidakovic S.
Videira J. F.
Videria J. F.
Vidya R.
Vieira A.
Vieira B.
Vieira Caroco T.
Vieira P.
Vieira Paiva Lopes A. C.
Vignali A.
Vigorita V.
Vijayan D.
Vilatoba M.
Vilendecic Z.
Villalabeitia Ateca I.
Vimalachandran D.
Vinayagam R.
Violante T.
Visgauss J.
Viswambaram P.
Viswanath Y.
Vitali A.
Vitone L.
Vives R. V.
Vo U. G.
Vogel J.
Vollkommer T.
Von Papen M.
Vovola F.
Vucic N.
Vujanac V.
Wade R.
Wadham B.
Waheed S.
Wai K.
Wali A.
Walker C.
Walker D.
Walkes K.
Wallwork K.
Walton G.
Walton T.
Waqar S. H.
Warburton H.
Ward D.
Ward S.
Waris Farooka M.
Warren O.
Waseem S.
Wasim T.
Watson D.
Watson L. J.
Watson N.
Weaver H.
Webber L.
Weitz J.
Welsch T.
Wensley F.
Werner J.
West C.
West D.
Westwood E.
Whelan M.
Whelan P.
Whisker L.
Whitehall E.
Whitmore H.
Wilkin R.
Wilkins A.
Williams G.
Williams J.
Williams K.
Williams M. A.
Williams T.
Williamson K.
Wilson M.
Wimberger P.
Wimmer A.
Winnand P.
Winter D.
Winter S.
Wolfer S.
Wong M. P. K.
Wong S.
Wong W. J.
Woodham A.
Woodun H.
Worku D.
Wright G.
Wullschleger M.
Wustrack R.
Xenaki S.
Xu M. J.
Xyda S. E.
Xynos E.
Yahaya A. S.
Yanez C.
Yang W.
Yassin N.
Ye G.
Yesantharao P.
Yesilyurt D.
Yetkin G.
Yiallourou A.
Yildirim A.
Yildiz A.
Ying Y.
Yip V.
Yordanov S.
Young R.
Yousof E. A.
Youssef A.
Youssef M.
Yuksel E.
Yurttas C.
Zacharoulis D.
Zafar S. N.
Zakai D.
Zakaria A. D.
Zakaria R.
Zakaria Z.
Zambelli M. F.
Zambon M.
Zamora L.
Zamvar V.
Zani S.
Zanotti S.
Zanus G.
Zapardiel I.
Zarabini A. G.
Zatecky J.
Zegarac M.
Zelic M.
Zeller N.
Zengin A. K.
Zerbib P.
Zervas K.
Zese M.
Zhang H.
Zivanovic M.
Zivkovic M.
Zizzo M.
Zografos C.
Zonta S.
Zorrilla Ortuzar J.
Zourntou S.
Zouzoulas D.
Zubaidi A.
Zullo A.
Publication venue: J Clin Oncol
Publication date: 01/01/2020
Field of study

PURPOSE: As cancer surgery restarts after the first COVID-19 wave, health care providers urgently require data to determine where elective surgery is best performed. This study aimed to determine whether COVID-19-free surgical pathways were associated with lower postoperative pulmonary complication rates compared with hospitals with no defined pathway. PATIENTS AND METHODS: This international, multicenter cohort study included patients who underwent elective surgery for 10 solid cancer types without preoperative suspicion of SARS-CoV-2. Participating hospitals included patients from local emergence of SARS-CoV-2 until April 19, 2020. At the time of surgery, hospitals were defined as having a COVID-19-free surgical pathway (complete segregation of the operating theater, critical care, and inpatient ward areas) or no defined pathway (incomplete or no segregation, areas shared with patients with COVID-19). The primary outcome was 30-day postoperative pulmonary complications (pneumonia, acute respiratory distress syndrome, unexpected ventilation). RESULTS: Of 9,171 patients from 447 hospitals in 55 countries, 2,481 were operated on in COVID-19-free surgical pathways. Patients who underwent surgery within COVID-19-free surgical pathways were younger with fewer comorbidities than those in hospitals with no defined pathway but with similar proportions of major surgery. After adjustment, pulmonary complication rates were lower with COVID-19-free surgical pathways (2.2% v 4.9%; adjusted odds ratio [aOR], 0.62; 95% CI, 0.44 to 0.86). This was consistent in sensitivity analyses for low-risk patients (American Society of Anesthesiologists grade 1/2), propensity score-matched models, and patients with negative SARS-CoV-2 preoperative tests. The postoperative SARS-CoV-2 infection rate was also lower in COVID-19-free surgical pathways (2.1% v 3.6%; aOR, 0.53; 95% CI, 0.36 to 0.76). CONCLUSION: Within available resources, dedicated COVID-19-free surgical pathways should be established to provide safe elective cancer surgery during current and before future SARS-CoV-2 outbreaks

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The INTOXICATE study: methodology and preliminary results of a prospective observational study

Author: Aage Wamberg Christian
Ababneh Hazim
Abdulwahed Eman
Achterberg Sefanja
Ahmed Ali Alshareea Entisar
Ahmed Hamed Aiman
Al-Awwady Ali Najeh
Al-Jarrah Amar
Al-Juaifari Maytham A.
Al-Shami Khayry
Al-Touny Shimaa Ahmed Hamed
Alali Mahmoud
Alnatour Hazem Zuhair Hussain
Altobal Ahmed
Arslan Mahmut
Aslanidis Theodoros
Aujayeb Avinash
Babayigit Munire
Badaras Robertas
Baker Stuart
Barral Segade Patricia
Ben Hasan Najat
Bergmans Dennis C. J. J.
Bilir Yeliz
Binnawara Muhannud
Biston Patrick
Boer Dirk P.
Boesen Hans Christian
Borggreve Hella F.
Brix Helene
Brommer Thirsa
Bueno-Vidales Nestor
Canas-Pérez Isabel
Carlier Maxim P.
Castellanos Esparraguera Alba
Cekic Deniz
Chico-Fernández Mario
Christiansen Lisbeth
Cobilinschi Cristian
Coelho Luis
Constantinescu Catalin
Cornet Alexander D.
Crescioli Elena
Cuenca-Rubio Cristina
Dargan Paul I.
Darie Raluca
de Lange Dylan W.
de Paula Delgado-Moya Francisco
De Schryver Nicolas
Dewulf Bram
Dieperink Willem
Druwé Patrick
Dubler Simon
Dufol Ana Ferrer
Duroux Maree
Elbahnasawy Mohamed
Elhadi Muhammed
Eroglu Ahmet
Eyüpoğlu Selin
Feria Gil Raquel
Fernandes Ana Silva
Ferrer Dufol Ana
Ferrer Carolina
Forsberg Sune
Franch-Llasat Diego
Gerritsen Rik T.
Ghmagh Reem
Gonzalez Londo��o Juliana
Grant Sølling Christoffer
Gravgaard Kjeld
Greco Massimiliano
Guerreiro Goncalo
Gustavsson Nicole
Güzeldag Seda
Halacli Burcin
Hamid Hytham K. S.
Hantson Philippe
Houwink Aletta P. I.
Hunault Claudine C.
Hvass Renner Block Malene
Jung Christian
Karasiali Stavri
Karghul Mohamed
Kaya Ebru
Khamees Almu’atasim
Koh Justin
Koopmans Matty
Kovacic Vedran
Laubner Sakalauskienė Gabija
Lindqvist Elin
Lladó Vilar Meritxell
Lolk Mette
Martín-Pérez Beatriz
Mateo Rodríguez Eva Maria
Mattijsen Hélène P.
Meelad Ayman
Miltenburg Iris
Mohamed Ahmed Ibrahim Mohamed
Moreno Rui
Morgom Marwa
Mucia-Anayaa Mercedes
Nafees Khalid Mahmood Khan
Nassredin Mohamed
Nurhikmahtul Aqilah Binti Haji Abd Rashid
Oostdijk Evelien A. N.
Ozkan Kuscu Ozlem
Pacheco Catarina
Palmqvist Dorte
Papachristou Despoina
Petrişor Cristina
Piagnerelli Michael
Pijper Wouter
Pérez-Torres David
Rabe Christian
Ratcliffe Megan
Reiter Nanna
Rezar Richard
Roche-Campo Ferran
Rodriguez-Ruiz Emilio
Roetert Harm
Ruiz Mena Ana Maria
Ruiz-Izquierdo Jessica
Rzayeva Vusala
Saidahmed Elfayadh
Sandström Gustaf
Saracoglu Kemal Tolga
Seelmaier Clemens
Serck Nicolas
Serón-Arbeloa Carlos
Stads Susanne
Stenbryggen Herløv Louise
Sultan Sahin Ayca
Thomsen Josefine
Topeli Arzu
Tran Yen
van den Bogaard Bas
van den Hengel-Koot Irma S.
van den Oever Huub L. A.
van der Horst Femke
van der Voort Peter H. J.
van Dielen Liam
van Duijn Abram L.
Van Hecke Jolien
van Herpt Thijs T. W.
van Holten Jantine
van Lelyveld-Haas Lenneke E. M.
van Sabben Nick
Vanderbiest Klaas
Vennick Marcussen Klaus
Vergotten Marie
Vermeijden Wytze
Viktorsdottir Ester
Wils Evert-Jan
Wittebole Xavier
Wolthuis Esther
Wood David M.
Wretman Max
Yahya Hana B.
Yavuz Cengizhan
Yaylaci Selcuk
Zalba Etayo Bego��a
Zwaag Samanta M.
Țincu Radu
Publication venue
Publication date: 01/01/2024
Field of study

Background There is currently no practice-based, multicenter database of poisoned patients admitted to intensive care units (ICUs). The INTOXICATE study, endorsed by the ESICM and EAPCCT, aimed to determine the rate of eventful admissions among acutely intoxicated adult ICU patients. Methods Ethical approval was obtained for this multicenter, prospective observational study, and data-sharing agreements were signed with each participating center. An electronic case report form was used to collect data on patient demographics, exposure, clinical characteristics, investigations, treatment, and in-hospital mortality data. The primary outcome, ‘eventful admission’, was a composite outcome defined as the rate of patients who received any of the following treatments in the first 24 h after the ICU admission: oxygen supplementation with a FiO2 > 40%, mechanical ventilation, vasopressors, renal replacement therapy (RRT), cardiopulmonary resuscitation, antidotes, active cooling, fluid resuscitation (> 1.5 L of intravenous fluid of any kind), sedation, or who died in the hospital. Results Seventy-eight ICUs, mainly from Europe, but also from Australia and the Eastern Mediterranean, participated. A total of 2,273 patients were enrolled between November 2020 and June 2023. The median age of the patients was 41 years, 72% were exposed to intoxicating drugs. The observed rate of patients with an eventful ICU admission was 68% (n = 1546/2273 patients). The hospital mortality was 4.5% (n = 103/2273). Conclusions The vast majority of patients survive, and approximately one third of patients do not receive any ICU-specific interventions after admission in an intensive care unit for acute intoxication. High-quality detailed clinical data have been collected from a large cohort of acutely intoxicated ICU patients, providing information on the pattern of severe acute poisoning requiring intensive care admission and the outcomes of these patients. Trial registration: OSF registration ID: osf.io/7e5uy

Repositorio Universidad de Zaragoza

Hochschulbibliothekszentrum des Landes Nordrhein-Westfalen (hbz)

Mortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection: an international cohort study

Author: Liza
- AP-HP) Bertrand Dousset (H\uf4pital Cochin
- APHP) Anne Thomin (H\uf4pital Trousseau
- ASST Rhodense) Carlo Corbellin (Ospedale Di Rho
- NYU Winthrop Hospital) Amir H Sohail (NYU Langone Health
- Xarxa Assistencial Universit\ue0ria de Manresa) Pablo Collera Ormazabal (Fundaci\uf3 Althaia
/ Columbia University Medical Center) Miriam Callahan (NewYork-Presbyterian
3 University Hospital) Bridget Egan (Tallaght
4 Lapolla Pierfrancesco
5 Spain: Eduardo E Rubio Susana Henriques (Hospital Garcia de Orta).
6 G\uf3mez Marcos
\u2013 IRCCS Francesca Gaino (Humanitas Clinical and Research Center
\u2013 Italy) 20089 Rozzano (MI)
\uc1ngel Hern\ue1ndez Bartolom\ue9 Miguel
A Aaraj Mahmoud
A Ayeni Funbi
A Bass Gary
A Benson Ruth
A Bozkurt Mehmet
A Breen Kerry
A Breen Kerry
A Breen Kerry
A Callcut Rachael
A Chung Eric
A Coughlin Patrick
A de Gheldere Charles
A De Marchi Joshua
A Elliott Jessie
A Fahey Brian
A Griffiths Ewen
A Griffiths Ewen
A Griffiths Ewen
A Guariglia Claudio
A Hirji Sameer
A Khalefa Mohamed
A Marra (Fondazione Policlinico Universitario Agostino Gemelli) Angelo
A Nguyen (Frankfurt University Hospital Truong
A Olson (Duke University Medical Center) Steven
A Raptis Dimitri
A Rollett Rebecca
A Saeed Samerah
A Salama Hiba
A Salamah Abdulrauf
A Schnitzbauer Andreas
A Schnitzbauer Andreas
A Singh Aminder
A Stevens Kent
A Stylianides Nicholas
A Thaha Mohamed
A Vega (12 de Octubre University Hospital) Viviana
A Vivas Alfredo
A Zappa Marco
Abate Emmanuele
Abdalaziz (Gloucestershire Royal Hospital) Hossam
Abdelkarim Mostafa
Abdou Hossam
Aboelkassem-Ibrahim Ahmad
Abuown Ala
Acebes-Garcia Fernando
Acharya Metesh
Adamina Michel
Addae-Boateng Emmanuel
Adolfo Pisanu (Cagliari University Hospital) Mauro Podda
Aftab Raiyyan
AG Moir John
Agarwal Arnav
AH Ibrahim Mohamed
Aitken (Queen Elizabeth University Hospital) Emma
Al-Azzawi Marwa
Al-Embideen Somya
Al-Sukaini Ahmad
Alakaloko Felix
Alam (Heartlands Hospital) Ruhina
Alameer Ehab
Alderson Derek
Ali Mohamed Ali (Queen Elizabeth Hospital King's Lynn) Inthekab
Aliyeva (Acibadem Mehmet Ali Aydinlar University Zumrud
Aljanadi Firas
Almasri Murad
Alonso Poza (Hospital Universitario del Sureste) Alfredo
Alonso-Ortu\uf1o Paula
Alser Osaid
Alser Osaid
Alser Osaid
Altintoprak (Sakarya University Faculty of Medicine) Fatih
Amalina Che Bakri Nur
Amjad Rabbia
Anania Gabriele
and Westminster Hospital NHS FT and Imperial College London) Chelsea
Andabaka Tatjana
Andrea Pisani Ceretti (ASST Santi Paolo e Carlo) Nicol\uf2 M Mariani
Angelou Dimitrios
Anita Volpe (New York Presbyterian Queens) Stephen Merola
Annamalai Seethalakshmi
Annessi Valerio
Anthoney James
Anuradha R Bhama (Rush University Medical Center) Alfonso Torquati
Anwar Sibtain
Aragon-Chamizo Juan
Ardito Antonella
Arigoni Michele
Armao Teodora
Arminio (Ospedali Riuniti Azienda Ospedaliera Universitaria Foggia) Armando
Armstrong Lara
Asaad Peter
Ashcroft James
Ashmore Christopher
Asqalan Ahmad
Asti (IRCCS Policlinico San Donato Emanuele
Aubry Emmanuelle
Aytac Erman
Ayuso-Herrera Esther
Azerbaijan:Elgun Samadov Joana FF Simoes (Chair). 2 Collaborators: (denotes Local Principal Investigator) Algeria: Faraj S Almaadany (\uc9tablissement Hospitalier Sp\ue9cialis\ue9 en Canc\ue9rologie - Centre Pierre-et- Marie-Curie).
B Avellana Rocio
B Catton Andrew
B Fonsi Giovanni
B Hing Caroline
B O'Meara Lindsay
B Schaffer Kathryn
B Yousuf (Tobruk Medical Center) Farhat
B\ue0mbina (Fabrizio Spaziani Hospital Fabrizio
Bailon-Cuadrado (Hospital Universitario R\uedo Hortega) Martin
Baldi Caterina
Baldini Edoardo
Baldo (Ospedale Santa Corona Stefano
Ballabio Michele
Baloyiannis Ioannis
Baltazar Gerard
Bandiera Alessandro
Barlow Emma
Barmasse (Ospedale Regionale Umberto Parini) Roberto
Barmpagianni Christina
Baronio (Policlinico San Pietro) Gianluca
Barra Fabio
Bartholomew's Hospital) St
Bartsch Anne-Marie
Basgaran Amedra
Basha Amr
Bashkirova (North Middlesex University Hospital) Varvara
Bastazza Marco
BB Sullivan (The Royal London Hospital) Tom
Beak Philip
Belcher Elizabeth
Belgium: Gabrielle H van Ramshorst Sevda Jafarova (Leyla Medical Center).
Beltr\ue1n de Heredia Juan
Belvedere Angela
Ben\uedtez-Linero Inmaculada
Benjamin Franklin) Campus
Bergeat Damien
Bernasconi Matteo
Bhalla Ashish
Bhangu Aneel
Bianco Federica
Bisagni Pietro
BJ Borgstein Alexander
Blake (Southport and Formby District General Hospital) Iain
Blanco-Colino Ruth
Blazquez-Martin (Hospital Principe De Asturias) Alma
Boal Matthew
Bologna) Ausl
Bonavina Giulia
Bonavina Luigi
Bond-Smith Giles
Booth (Freeman Hospital) Karen
Borges Filipe
Borghi Felice
Borja De Lacy (Hospital Clinic Barcelona) F
Bourke Grainne
Boyle Emily
Brachini Gioia
Brain Jessie
Brar Amanpreet
Breckles Lisa
Brendan L Skelly (Altnagelvin Area Hospital) Catherine Rossborough
Brianza) Carate
Brixton Genevieve
Bruzzaniti Placido
Bueser Teofila
Burnside Nathan
C Bosanquet David
C Brown (Manchester University NHS Foundation Trust Benjamin
C De Souza Anthony
C Glasbey James
C Glasbey James
C Hopkins James
C Lauscher Johannes
C McIntyre Robert
C Mckay Siobhan
C Neary Paul
C Nugent III William
C Rodriguez-Sanjuan (Marqu\ue9s de Valdecilla University Hospital) Juan
C Roslani April
C Tucker Sarah
C Velmahos (Massachusetts General Hospital) George
C Winter Stuart
Caballero Albert
Cairo University) Mahmoud MA Elfiky (Kasr Alainy Faculty of Medicine
Calcerrada-Alises Enrique
Camacho Fern\ue1ndez-Pacheco (Complejo Hospitalario Universitario Insular-Materno Infantil) Borja
Camarero Enrique
Campagnaro Tommaso
Campanelli Michela
Candiani Massimo
Cannoletta (Royal Brompton Hospital) Marina
Cantalejo-Diaz (Hospital Universitario Miguel Servet) Miguel
Cao Han
Capizzi Vita
Carcano (Ospedale di Circolo Giulio
Carissimi Francesca
Carlini Massimo
Carlos Bernal-Sprekelsen Juan
Carlos Catal\ue1 Bauset (Consorcio Hospital General Universitario) Juan
Carlucci Michele
Carmela Giuffrida Maria
Carmichael Heather
Carrasco Milagros
Carrillo Mariana
Carvello Michele
Casati Massimiliano
Castoro Carlo
Castro Ruiz Carolina
Catalan Vanesa
Catriona R Luney (Nuffield Orthopaedic Centre) Benjamin JF Dean
Cavaleiro Salom\ue9
Cellerino Paola
Center Amsterdam) Cancer
Centinaio (Ospedale Maggiore di Lodi) Giovanna
Cernei Cristina
Cervellera Maurizio
Chakrabortee Sohini
Chamberlain Stephanie
Chan Jeffrey
Chang Grace
Chaudhry Daoud
Chebaro Alexandre
Chen (Jamaica Hospital) David
Chetty Govind
Chia (Royal Derby Hospital) Zoe
Chiappini Ambra
Chiarugi (Azienda Ospedaliero Universitaria Pisana) Massimo
Chidambaram Swathikan
Chiozza Matteo
Cholewa Hanna
Chong (Evelina London Children's Hospital) Clara
Choolani-Bhojwani Ekta
Christian Cotsoglou (ASST Vimercate) Stefano Granieri
Chui Karen
Chung Choyin
Cirillo Bruno
Citterio Davide
Clermidi Pauline
Coccolini Federico
Colletti Gaia
Compagnoni Bruno
Concepci\uf3n-Mart\uedn Vanesa
Confalonieri Marco
Connolly Hannah
Conso Christel
Conti Luigi
Cooper Zara
Corral Javier
Costa Marta
Costanzi Andrea
Cox Daniel
Cozza Valerio
CR Wormald Justin
Croatia: Jakov Mihanovic Nicolas Duchateau (Heilig Hart Ziekenhuis Lier).
CS Clough Ethan
Cuming Tamzin
Cuneo)
Curtis Miles
Cuschieri Joseph
D Baron Ryan
D Bosch Karen
D Brown Oliver
D Bueno-Ca\uf1ones Alejandro
D Cato Liam
D Drake Thomas
D Jenkinson Michael
D Jenkinson Michael
D Liyanage Aloka S
D Pinkney Thomas
D Rajgor Amarkumar
D Stewart Grant
D Tebala Giovanni
D'Agruma Michele
D'Andrea Giancarlo
D\uedaz P\ue9rez David
D\uedaz-Garc\ueda (Hospital Universitario Nuestra Se\uf1ora de Candelaria) Alberto
Da Roit Anna
da Saliceto\u201d Patrizio Capelli (Ospedale \u201cG.
Dare Oliver
Darko Ebenezer
Data Monitoring and Ethics Committee: Deborah S Keller H. Hunt Batjer (University of Texas Southwestern).
Day Andrew
De Andr\ue9s-Asenjo Beatriz
de Medicina Facultad
De Miguel-Ardevines Maria-Carmen
De Nardi Paola
De Simone Veronica
De Toma Giorgio
Deepti Sinha (University College London Hospital) Nicholas Kalavrezos
Dehal (Kaiser Permanente Panorama City Medical Center) Ahmed
Dehart Dustin
Del Giudice Roberto
Delgado-Oliver Eduardo
Denmark: Henry G Smith Bernarda Bakmaz (Zadar General Hospital).
Denning Max
Desai Anant
Desender (Ghent University Hospital) Liesbeth
Dester (ASST Valcamonica Ospedale di Esine) Sara
Di Candido Francesca
Di Chiara Francesco
Di Franco Gregorio
Di Giuseppe (Ente Ospedaliero Cantonale del Canton Ticino) Matteo
Di Saverio Salomone
Di Saverio Salomone
Di Saverio Salomone
Di Saverio Salomone
Diaz-Pe\uf1a Patricia
Dieguez Fernandez Beatriz
Dissemination Committee: Michel Adamina Aneel Bhangu.
Dolores Del Toro M
Domodossola
Doussot Alexandre
Duff Sarah
Dunning Joel
Dunstan Matt
Duque-Mallen Victoria
Dziakova Jana
E Canova Michaela
e Carle Hospital Chiara Peluso (Santa Croce
e Carlo ASST Santi Paolo
E Dawson Brett
E Dickson Kathryn
E Hudson Victoria
E Jenny (Johns Hopkins Hospital) Hillary
E Lewis Sophia
E Nita George
e Oftalmico) Giulio Iacob (Ospedale Fatebenefratelli
E P\ue9rez-S\ue1nchez Luis
E Rice Henry
E Ssentongo Anna
e Universit\ue1rio de Coimbra) Ana C Almeida (Centro Hospitalar
E Xyda Souzana
Edward Fitzgerald J
EF Abbott Tom
EF Abbott Tom
Egan Richard
Egypt: Mohamed El Kassas University of Copenhagen).
El Youzouri Hanan
El-Ali (Queen's Hospital Abess
Elaine YL Leung (The Pan Birmingham Gynaecological Cancer Centre) Sudha Sundar
Elfeki Hossam
Elhadi Muhammed
Eljareh (Aljalaa Hospital) Mohammed
Elkadi Hannah
Elkady Ramy
Elkhafeefi Fatimah
Elmore Ugo
Elmoslemany (The Walton Centre NHS Foundation Trust) Tarek
EM Bouhuwaish Ahmad
EM Brathwaite Collin
Emmerson (North Manchester General Hospital) Oliver
Enemosah Ibrahim
English Camilla
English William
Ereidge Simon
Escartin Jorge
Estaire-Gomez Mercedes
EuroSurg
Evans (Queen Elizabeth the Queen Mother Hospital Margate) Jessica
Exley Rebecca
F Bath Michael
F Cunha Miguel
F Cunha Miguel
F Davis Niall
F Ridgway Paul
Fabbri Nicol\uf3
Falco Giuseppe
Familiari Pietro
Fancellu (Cliniche San Pietro Alessandro
Fanjul G\uf3mez Mar\ueda
Farik Shebani
Farr\ue9 Font Roser
Farrell Tony
Fehervari Matyas
Fell Adam
Fern\ue1ndez- Mart\uednez Mar\ueda
Fern\ue1ndez-Gomez Cruzado (Hospital Urduliz) Laura
Fern\ue1ndez-Mar\uedn Reyes
Fernandez-Camu\uf1as Angel
Ferrara)
Ferrara Francesco
Ferrari Guglielmo
Ferrero Simone
FF Simoes Joana
FF Simoes Joana
Findlay Laura
Fiore Marco
Fiore Marco
Fiori Enrico
FJ Dunne Declan
Flatman Michael
Flindall Ian
Fontana (Vittorio Emanuele Tommaso
Ford (The Robert Jones and Agnes Hunt Orthopaedic Hospital) David
Ford Samuel
Forlani Stefano
Fr\ue9d\ue9ric Bretagnol (H\uf4pital Louis-Mourier - GHU AP-HP. Nord - Universit\ue9 de Paris) David Moszkowicz
France: Zaher Lakkis Mohamed Sherief (MISR Cancer Center/MISR International Hospital).
Francisco de Vitoria Universidad
Francone Elisa
Frattaruolo Colomba
Frio (Institute of Neurological Sciences of Bologna Federico
Frosinone)
G Aoun Salah
G Barranquero Alberto
G Blazer III Dan
G Collins Chris
G Edwards John
G Edwards John
G Morton Dion
G Povey Meical
G Velopulos Catherine
G Wade Ryckie
Gabriel Kinnaman (IU Health Methodist Hospital) Ashley D Meagher
Gagliano Annalisa
Gagliardi Filippo
Gahunia Sukhpreet
Gala Tanzeela
Galfrascoli Elisa
Galimberti Luca
Galindo Jara (Hospital Universitario de Torrej\uf3n Pablo
Gallagher Phoebe
Galleano Raffaele
Gallo Gaetano
Gallo Gaetano
Gallo Gaetano
Galv\ue1n-P\ue9rez Armando
Gamal Amira Ibrahim Sallam
Gammeri Emanuele
Ganau Mario
Garc\ue9s-Garc\ueda Ra\ufal
Garcia Fernandez Andres
Garcia-Conde Delgado Maria
Garulli (Ospedale Infermi di Rimini) Gianluca
Gascon-Ferrer Isabel
Gattolin (Regina Montis Regalis Hospital Andrea
Gaujoux Sebastien
Gentilli Sergio
Georgiades Fanourios
Germany: Carsten Kamphues Didier Ollat (Institut Mutualiste Montsouris).
Gerogiannis (Kingston Hospital NHS Foundation Trust) Ioannis
Ghanbari (Homerton University Hospital) Amir
Ghosh Dhruv
Giacometti Marco
Giblin Anna-Victoria
Gilbert (Surrey and Sussex Healthcare NHS Trust) Catherine
Gim\ue9nez Clara
Giorgakis Emmanouil
Gipponi Manuel
Glen Paul
GlobalPaedSurg GlobalSurg
Goatly Giles
Gobatti (San Carlo Borromeo Hospital Davide
Godbole Chintamani
Gohil Kajal
Gomez-Rosado Juan-Carlos
Gonullu Emre
Gonzalez-De Miguel Melania
Gonzalez-Gonzalez Enrique
Gordini Luca
Gracia Isabel
Gracia-Roche Carlos
Greece: Konstantinos Bouchagier Markus W L\uf6ffler (University Hospital Tu\u308bingen).
Green Susanna
Grivon Manuela
Grove (Department of Colorectal Surgery Thomas
Guaglio Marcello
Guaitoli (Perrino) Eleonora
Guglielmi Alfredo
Guha Soumya
Gustavino (Unit of Obstetrics and Gynecology IRCCS Ospedale Policlinico San Martino Genoa) Claudio
Guti\ue9rrez Samaniego Mar\ueda
H Babu Bheemanakone
H Chowdhury Abeed
H Davidson Giana
H Davidson Giana
H Davidson Giana
H Elfallal Ahmed
H Emile Sameh
H Kirmani Bilal
H Liu Helen
H Murphy Suzanne
H van Ramshorst Gabrielle
H\uf6lzle Frank
Habeeb Amir
Hagger Robert
Hakmi Hazim
Halkias Constantine
Halkias Constantine
Hampton (Rotherham District General Hospital) Matthew
Handa Siddhartha
Haq Iram
Harky (Liverpool Heart and Chest Hospital) Amer
Harries (Morriston Hospital Rhiannon
Harrison Joseph
Hasan Raashad
Hawari Mohammad
Hawkin Paul
Hebblethwaite Bethany
Helier University Hospitals NHS Trust) St
Heritage Emily
Hernandez Garcia Miguel
Hernandez-Juara Pilar
Herrero-Lopez Maria
Hervieux Erik
Heyd Bruno
Higgs Simon
Hitchman (Hull University Teaching Hospitals NHS Trust) Louise
Ho Beatrice
Hogan Aisling
Hospital of Varese University
Hospital Universitario del Henares) Miguel Angel Garcia-Ure\uf1a (Universidad Francisco de Vitoria
Hospital) Atakent
Hospital) Wythenshawe
Hossain Tanvir
Houston Roy
Hurt Libor
HV Byrne Matthew
i Pujol) Alba Zarate (Hospital Germans Trias
I Roxo (Brigham and Women's Hospital) Vanessa
I van Berge Henegouwen (Amsterdam UMC Mark
I Alessandro Di Bartolomeo (Policlinico Umberto
Iannone Immacolata
Ibrahim Sherif
Iovino Domenico
Ireland: Arnold DK Hill Paraskevi Tourountzi (Kavala General Hospital).
Isik Arda
Israel: Oded Zmora Thomas M Aherne (Galway University Hospital).
Italy: Maurizio Zizzo Nadav Kugler (Shamir Medical Center).
J Abbott Sarah
J Baker Olivia
J Baldwin Alexander
J Beamish Andrew
J Carlos William
J Caruana Edward
J Caruana Edward
J Davies Emma
J Diaz Jose
J Doe Matthew
J Eardley Nicola
J Fern\ue1ndez Antonio
J G\uf3mez D\uedaz Carlos
J Hainsworth Alison
J Hall Bria
J Holme Thomas
J Hutchinson Peter
J Hutchinson Peter
J Kalkwarf Kyle
J Lin Daniel
J Lowery Aoife
J McCluney Simon
J Mehigan Brian
J Mills Sarah
J Pachl (Birmingham Children's Hospital) Max
J Rogers Luke
J Ryan \uc9anna
J Scurrah Rachel
J Shackcloth Michael
J Smart Neil
J Steinkamp Pieter
J Tejero-Pintor Francisco
J Thomas Amy
J Torres Antonio
J Warren Oliver
J Warren Oliver
J Williams Katherine
James RW Hall (Stepping Hill Hospital) Claire Hall
James's Hospital) Conor P Barry (St.
Jamil Tahir
Jayaraju (University Hospital of Wales) Ullas
Jenner Edward
JG Chase Thomas
Jha Shane Lester (James Cook University Hospital) Madan
Jimenez-Higuera Elisa
Jimeno Jaime
JM Dunne Naomi
JM Ferguson Henry
Jo\ue3o Lima Maria
Johnstone Jack
Jones Mark
Jordan: Mahmoud Al-Masri Gela).
JS Wall Joshua
Judkins Nicholas
JW Wilkin Richard
K Abou Chaar Mohamad
K Ambler Graeme
K Bankhead-Kendall Brittany
K Bankhead-Kendall Brittany
K Bankhead-Kendall Brittany
K Brown Allison
K Fusai Giuseppe
K Gill Charn
K Kamarajah Sivesh
K Patel Panna
K Ubhi Harmony
K Weerasinghe Chamindri
K\uf6nigsrainer Alfred
Kalidindi Venugopala
Kamal Mona
Kang Chong
Kara Yasin
Karam Edward
Karim Ahmed
Kashora Florence
KC Jonker (University Medical Center Groningen (University of Groningen) Pascal
Kearney (Beaumont Hospital) David
Khajuria Apoorva
Khan Azam
Khan Umul
Khatri Chetan
Kinross James
Kler Aaron
Klimopoulos (Evangelismos General Hospital) Serafeim
Kocata\u15f (Kanuni Sultan Suleyman Training and Research Hospital) Ali
Kolias Angelos
Kolias Angelos
Kontovounisios Christos
Kourdouli (Leicester Royal Infirmary) Amar
Krishnan Emily
Kristinsson Sverrir
Kruijff Schelto
KS Viswanath Yirupaiahgari
Kudsk-Iversen S\uf8ren
Kufeji Dorothy
Kulkarni Rugved
Kurihara Hayato
L Biffl Walter
L Coleman Natasha
L Collins Michelle
L Engel (Temple University Hospital) Jamie
L Fowler Amy
L Garcia Galocha Jose
L Hughes Jane
L J\uf6nsson (Bispebjerg Hospital Maria
L Labib Peter
L Marsh (Scripps Memorial Hospital) Christopher
L McKevitt Kevin
L Osorio Alexander
L Romera Jose
L Serevina Olivia
L Venn Mary
L Venn Mary
L Venn Mary
L Wright Franklin
L Young Alastair
L\ue1zaro Andr\ue9
La Torre Filippo
Laface (Ospedale Vittorio Emanuele III Letizia
Lami Mariam
Landaluce-Olavarria Aitor
Laura Hansen 9
Lawani Ismail
Lawday (Southmead Hospital) Samuel
Lawday Samuel
Le Roy Bertrand
Lecco) Asst
Lecolle Katia
Lederhuber Hans
Lederhuber Hans
Leeds)
Leicester)
Leventoglu Sezai
Li Elizabeth
Li Elizabeth
Li Zoe
Libya: Ghadah Z Alkadeeki Hani Al-Najjar (King Hussein Cancer Center).
Liew Ignatius
Ligure (SV) Pietra
Lima Buarque Igor
Lisi Giorgio
Lizzi Vincenzo
Lo Terence
Lombardia) Regione
Lomiento Daniele
Longhi Marco
Lopez Antonanzas (Hospital Clinico San Carlos Leyre
Losada Ruiz Manuel
Lostis Emilie
Lostoridis Eftychios
Loubani Mahmoud
Lowy- Benoliel Alejandro
Lucianetti (Papa Giovanni XXIII Hospital) Alessandro
Luigi MP Marino Cosentino (PO San Filippo Neri - ASL ROMA 1) Andrea Sagnotta
luis Blas Laina Juan
Luke Evans (Norfolk and Norwich University Hospital) Mina MG Youssef
Luke Louis
Lunevicius Raimundas
Luraghi Marco
Lye George
M Alrahawy (Menofiya University Hospital) Mahmoud
M Andreani Stefano
M Ashoush Fouad
M Bajomo Oreoluwa
M Blundell Chris
M Cicerchia Pierfranco
M Connolly Tara
M Diez-Alonso Manuel
M Dur\ue1n-Mu\uf1oz-Cruzado (Hospital Universitario Virgen del Rocio) Virginia
M Emslie Katy
M Harrison Ewen
M Holbrook Charlotte
M Isolani Simone
M Keatley James
M Leite-Moreira Andr\ue9
M Mithany Reda H
M Mohan Helen
M Mohan Helen
M Monteiro Joana
M Morgom (Tripoli Central Hospital) Marwa
M Muguerza Jose
M Nunes Quentin
M Nygaard Rachel
M Omar Aneel Bhangu Omar
M Philp Matthew
M Pollok Joerg
M Rooney Siobhan
M Sampietro Gianluca
M Sewards Joseph
M Tang Alethea
M Trout Isobel
M Walters (Harborview Medical Center Andrew
MA Kaafarani Haytham
MA Kaafarani Haytham
MA Kaafarani Haytham
Maarten van Heinsbergen (VieCuri Medisch Centrum) Joop Konsten
Mabrouk Islam
Macchi Alberto
MacDonald Luisa
Machairas (Royal Free Hospital) Nikolaos
Madonini Marco
Madrid)
Madrid)
Magalh\ue3es Maia Mariana
Magne Augestad Knut
Magowan Drew
Maha H Haqqani (Boston Medical Center) Frederick T Drake
Maisonneuve Emeline
Majkowska Agata
Majkowski (Northern General Hospital Lawrence
Mak (Queen Elizabeth Hospital Birmingham) Jason
Malabarba Stefano
Malerba Michele
Maninder Kalkat 7
Mannan Syed
Manson Joanna
Mansuri Ahmer
Mantoglu (Sakarya University Research and Educational Hospital) Baris
Manu Nichola
Manzoni 56 Via
Maqsood Afnan
Marano Alessandra
Marchbank Adrian
Marcos-Santos Pablo
Marinos Kouris (Buckinghamshire Healthcare NHS Trust) Spyros
Marqueta De Salas Maria
Marrano Enrico
Mart\uedn-Rom\ue1n Lorena
Mart\uednez P\ue9rez Carolina
Mart\uednez-dePaz Fernando
Martel Lozano Saida
Martin (St Mary's Hospital) Guy
Martin Emmeline
Martin Janet
Martin-Albo Lorena
Martine Uittenbogaart (M\ue1xima Medical Center) Wouter KG Leclercq
Martinelli Fabio
Martinez-German Antonio
Martinez-Pinedo Carlos
Martins Ricardo
Marwan Hisham
Marzi Federica
MAS Baig Mirza
Mateos-Sierra (Hospital General Universitario Gregorio Mara\uf1\uf3n) Olga
Mater Studiorum University of Bologna) Alma
Mathieu (CHU Besan\ue7on) Pierre
Matute-Najarro Maria-Soledad
Maw Andrew
Mazingi Dennis
Mazzaferro (Fondazione IRCCS Istituto Nazionale dei Tumori Vincenzo
McCanny (Antrim Area Hospital) Andrew
McKenzie Katherine
McLarty (Northumbria NHS Hospital Trust) Nicola
McPherson Iain
Medina Esther
Mediratta Saniya
Medone Marzia
Mehra (Guy's and St Thomas\u2019 NHS Foundation Trust) Gautam
Mele Simone
Melero-Cort\ue9s Lidia
Melody Baeza (Morales Meseguer University Hospital) Jos\ue9 Aguilar
Mendon\ue7a Ata\uedde Gomes Gustavo
Mendoza-Moreno Fernando
Meneghini Simona
Merate
Mercante Giuseppe
Merdrignac (Rennes University Hospital) Aude
Metallidis Symeon
Michel (Pinderfields Hospital) Martin
Migliore Marco
Milan)
Milan)
Milan)
Miller Douglas
Minaya- Bravo Ana
Minaya-Bravo Ana
Minaya-Bravo Ana
Minaya-Bravo Ana
Mingoli Andrea
Minto Gary
Mirabella Antonello
Misra Nikhil
Mitrasinovic Stefan
Miu Victor
Moawad (Royal Victoria Hospital) Nader
Mochet Sylvie
Modabber Ali
Mohammad Adam
Mohan Midhun
Moliner-S\ue1nchez Carmen
Mondov\uec)
Mongelli Francesco
Monteleone (Ospedale San Leopoldo Mandic Michela
Montuori Mauro
Moore Rachel
Mora-Guzm\ue1n (Hospital Santa B\ue1rbara) Ismael
Morales Dieter
Morales Xavier
Morelli Luca
Morelli Lucia
Morgan Richard
Morris Chris
Mortini Pietro
Mosca Angelo
Moszkowicz David
Moszkowicz David
Motter Dema
Moug Susan
Mukherjee Samrat
Munoz Rivas Ana
Murcia)
N Bence Matthew
N Hopkinson David
N Mashbari Hassan
N Mashbari Hassan
N Mashbari Hassan
N Naumann David
N Rao Jagan
N Townshend David
N\ufa\uf1ez Jordi
Najdy Manhal
Nakas (Glenfield Hospital Apostolos
Namazov Ilgar
Naredla Pradyumna
Nasef Emmhamed
Nassa Heeam
Nath Rahul
Navarro-S\ue1nchez Antonio
Nazarian (Bupa Cromwell Hospital) Scarlet
Neal Bhutiani (University of Louisville Hospital and Norton Hospital) Robert CG Martin
Negri Giampiero
Nehra Deepika
Neil-Dwyer Jason
Nepogodiev Dmitri
Nepogodiev Dmitri
Nepogodiev Dmitri
Neri Jacopo
Netherlands: Suzanne S Gisbertz Mustafa R Bulugma (Zawia Teaching Hospital). Mexico: Fernando Cordera (ABC Medical Center).
Newton (Manchester Royal Infirmary) Katy
Nikaj (Azienda Ospedaliero Universitaria Maggiore della Carit\ue0 Herald
Niquen Milagros
Nobile (Azienda Ospedaliera Universitaria Integrata di Verona) Sara
Nogueiro Jorge
Nogues Pevidal (Royo Villanova) Ana
Novara)
Ntirenganya Faustin
Nugent Michael
O Ademuyiwa Adesoji
O Kavanagh Dara
O Larkin John
Oca\uf1a Juan
of Amsterdam University
of Ferrara) University
of Insubria University
of Milan) University
of Surgeons in Training (ASiT) Association
of Surgery) Department
of Washington) University
Okafor Barbara U.
Okechukwu Valentine
Oliva-Mompean (Hospital Universitario Virgen Macarena) Fernando
Oliveira Ana
OM Abdalla Mutwakil
Omar M Omar
OO Ayorinde John
Osagie-Clouard (Epsom &amp
Osman (Walsall Manor Hospital) Khabab
Ottolina Jessica
Ourieff (Mount Sinai Hospital) Jared
Outani Oumaima
Oyewole Bankole
P Arnaud Alexis
P Arnaud Alexis
P Arnaud Alexis
P Baker Markus
P Belgaumkar Ajay
P Boddy Alexander
P Duffy (Nottingham City Hospital) John
P Evans Jonathan
P Hazelton Joshua
P Jones Andrew
P Jones Robert
P Joyce Doireann
P Kisiel Aaron
P Pezzuto Anna
P Singh Rabindra
P\ue9rez-Gonz\ue1lez Marta
P\ue9rez-Saborido Baltasar
Pacheco-Sanchez David
Padilla-Valverde (Hospital General Universitario De Ciudad Real) David
Pai (Hammersmith Hospital) Madhava
Paiella Salvatore
Paisley (Brighton and Sussex NHS Trust Samuel
Palermo)
Palini Gianmarco
Palmeri Matteo
Parente Alessandro
Parlanti Daniele
Parmar Chetan
Pascual Angela
Pata Francesco
Pata Francesco
Patel Mahul
Pathak Abhijit
Patil Sangram
Pattyn Piet
Peckham- Cooper Adam
Pedram Panahi (University Hospitals Plymouth NHS Trust) Mariam Rela
Pedrazzani Corrado
Pellino Gianluca
Pereira Andr\ue9
Pereira-Neves Ant\uf3nio
Perez-Diaz Md
Perivoliotis (General University Hospital of Larissa) Konstantinos
Perkins Clare
Perotto (CHU Saint Etienne) Ornella
Perra Teresa
Petrone Patrizio
Phenix George
Piacenza)
Picazo Sara
Picon-Rodriguez Rafael
Piloni Martina
Pingarr\uf3n-Mart\uedn Lorena
Pinotti Enrico
Pizzini Paolo
PM de Vries Jean-Paul
Pockney Peter
Podolsky Dina
Poggioli Gilberto
Pompili Cecilia
Pontari Michael
Porcu Alberto
Portugal: Hugo Santos-Sousa Pakistan: Mariyah Anwer (Jinnah postgraduate medical center).
Potter (Royal Bournemouth Hospital) Ryan
Price Claire
Prita Daliya 8
Pruvot (Lille University Hospital) Fran\ue7ois-Ren\ue9
PTSurg ItSURG
Pujol-Muncunill Roger
Puppo Andrea
Q Mehdi (University of Texas Medical Branch) Mohammad
Quante Markus
Quintana-Villamandos Bego\uf1a
Qureshi Ali
R Burke Joshua
R Davidson Brian
R Dixon Jan
R Fretwell Kenneth
R Gujjuri Rohan
R Gujjuri Rohan
R Kowal Mikolaj
R O\u2019Neill John
R Sarma Diwakar
R Spalding Duncan
R Springford Laurie
Rachel Baumber (Royal National Orthopaedic Hospital) James T Parry
Radenkovic Dejan
Rahman Saad (Medway Maritime Hospital) Abdel
Rakvin Ivan
Ramallo-Sol\ueds Irene
Ramcharan Sean
Ramos Diego
Ramos-Bonilla Antonio
Ramos-De la Medina Antonio
Ramzi Joussi
Rathinam Sridhar
Rausa Emanuele
Ravaioli Matteo
Ravindran Sharanya
Raymond (Royal Lancaster Infirmary) Thomas
Razik Aisha
Redfern (Furness General Hospital) Jennifer
Reguera-Rosal Julio
Rey-Biel Juan
Rey-Valcarcel Cristina
RG Sheel Andrea
Ribolla Marta
Richards Tomos
Richmond (University of Maryland Medical Center) Michael
Righini (Ospedale del Delta Erminio
Rio-Gomez Javier
Riuniti Villa Sofia-Cervello Ospedali
Riyat Harjoat
Rizvi Sana
Roberts Keith
Roberts Matthew
Robertson (University Hospitals Coventry and Warwickshire) Stuart
Robertson (University of Arkansas for Medical Sciences) Ronald
Robin-Valle Alvaro
Rochon Melissa
Rojo Mikel
Rolli Luigi
Romano Silvio
Rome)
Romford)
Ross Elizabeth
Ross Howard
Rottoli Matteo
Royal Hospital) Princess
Ruiz (Hospital General Universitario Reina Sof\ueda Miguel
Ruiz- Grande Fernando
Ruiz-Martin (Rey Juan Carlos University Hospital) Irene
Ruiz-Soriano (Hospital Cl\uednico Universitario de Valladolid) Mar\ueda
Ruzzenente Andrea
Ryska Ondrej
S Abdelaal (Alexandria Main University Hospital) Ahmed
S Al Maadany Faraj
S Faria Carlos
S Hammond John
S Hossain Fahad
S Jeyaretna Deva
S Jones Conor
S Khan (Queen Alexandra Hospital) Jim
S Moura Francisco
S Ng-Kamstra Joshua
S Sica Giuseppe
S Tamimy Muhammad
S Wadley Martin
S\ue1nchez- Arteaga Alejandro
SA Taher Ahmed
Saez Carlos
Sahnan Kapil
Sahni Arun
Salim Ali
Salvia Roberto
Sammarco Giuseppe
Sampaio-Alves Mafalda
San Miguel-Mendez Carlos
Sanchez del Pueblo Cristina
Sanchez-Fuentes Maria-Nieves
Sanchez-Pelaez Daniel
Sanchez-Perez Coral
Sanchez-Rubio Maria
Sancho-Muriel Jorge
Sanchon Fructuoso Lorena
Sanders Julie
Santero-Ramirez Maria-Pilar
Santora Thomas
Santoro Antonio
Santos Irene
Sapienza Paolo
Sartarelli (Sant\u2019Orsola Hospital Lodovico
Sarveswaran Janahan
Sasia Diego
Sassari) A. O. U.
Saudemont Alain
Saudi-Moro Sef
Saxena Dolly
Saxena Shobhit
Sayasneh Ahmad
Scalabre Aurelien
Schache Andrew
Schiavina Riccardo
Schineis (Charit\ue9 University Medicine Christian
Schreckenbach Teresa
Scorza Antonella
Scott Lucy
Seegert (ProMedica Toledo Hospital) Sara
Seguin-Givelet Agathe
Senent-Boza Ana
Serrano Gonz\ue1lez Javier
Sette Laghi Asst
Seymour Keith
Shabana Amanda
Shah (The Whittington Hospital) Sujay
Shah Jigar
Shah Karishma
Shah Preena
Shakir Taner
Shalaby (Mansoura University Hospital) Mostafa
Shankar (Oxford University Hospitals NHS Foundation Trust Sushma
Shaw Richard
Sheffield)
Shehata Sameh
Shelley Hwang E.
Shen Ban Vin
Shenfine Amy
Sheridan Kelda
Sherief Ahmed
Sherif Mohamed
Shinkwin Michael
Shu Sebastian
Siaw-Acheampong Kwabena
Sileri (San Raffaele Scientific Institute Pierpaolo
Singh Abhinav
Singh Shailendra
Sinha Sanjay
Siragusa (Policlinico Tor Vergata Hospital Leandro
Sivaprakasam Rajesh
Sivayoganathan Sriharan
SJ Ledesma Frances
Smillie Robert
Smith (Countess of Chester Hospital) Claire
Smith Andrew
Smith Christopher
Sochorova (Royal Liverpool University Hospital) Dana
Society of Coloproctology (ESCP) European
Society of Colorectal Surgery (SICCR) Italian
Soggiu Fiammetta
Sohrabi (St Bartholomew's Hospital) Catrin
Sohrabi (Whipps Cross University Hospital) Catrin
Sohrabi Catrin
Solari (Royal Gwent Hospital) Francesca
Solli Piergiorgio
Soreide Kjetil
Soto Montesinos Cristina
SpainSurg
Spinelli Antonino
Spinelli Antonino
Spoletini (Sant'Eugenio Hospital) Domenico
Spriano Giuseppe
Sravanam Sanskrithi
Ssentongo (Pennsylvania State University) Paddy
Stanger Sophie
Stavroulias Dionisios
Steel (Sunderland Royal Hospital) Ben
Stella Marco
Stewart Robbie
Stringer Sally
Sudan: Osman M Ali Elima P Cagigal- Ortega (Hospital Universitario Severo Ochoa).
Sulen Nina
Sundar Sudha
Sundhu (Aintree University Hospital) Matthew
Surgical Research Collaborative (ISRC) Irish
Suri (University of California Davis Health Avni
Swansea)
Switzerland: Dimitri Christoforidis Ali A Ali karar (Al-rajhi).
Syed Arooj
Szatmary Peter
T Colonna Emily
T Enjuto Diego
T Montella (Azienda Unit\ue0 Sanitaria Locale-IRCCS di Reggio Emilia) Maria
TA Neely David
Tabiri Stephen
Tadross Daniel
Taglietti Lucio
Tansey (Princess Alexandra Hospital) Rosamond
Tartaglia Dario
Tawheed (Endemic Medicine Department Ahmed
Tayeh Salim
Testa Valentina
Tewari Nilanjana
Thoenissen Philipp
Thomas (Worcestershire Acute Hospitals NHS Trust) Kane
Thrush Jessica
Tierney Sean
Tiwari Abhinav
Tobias Teles (Hospital de Cascais - Dr. Jos\ue9 de Almeida) Pedro A Serralheiro
Toledo Enrique
Tonini Valeria
Torkington Jared
Torzilli Guido
Totty Joshua
Tousidonis Manuel
Townend Philip
Townsend Catherine
Trompeter (St George's Hospital) Alex
Trotta Francesco
Truant St\ue9phanie
Trujillo-D\uedaz Jeancarlos
Tsoulfas George
Tsoulfas Georgios
Turco Celia
Turkey: Volkan Ozben Georgios Peros (Kantonsspital Winterthur).
Turrado- Rodriguez Victor
Turri Giulia
Tustin (Cumberland Infirmary) Harry
Tyler Jayne
Tzedakis Stylianos
Tzovaras George
Ullah Ramzan
Unit\ue0 Sanitaria Locale di Ferrara Azienda
United Kingdom: Richard J Davies Alp Yildiz (Yildirim Beyazit University Yenimahalle Training and Research Hospital).
United States: John RT Monson (AdventHealth Orlando) Lavinia Onos (York Teaching Hospitals NHS Trust).
University Hospitals NHS Trust) Nottingham
University of Rome) Sapienza
University) Goethe
University) Helwan
Urban (University of Colorado Hospital) Shane
Urbani (Azienda Ospedaliero Universitaria San'Anna Alessia
Usai Antonella
V Bhavaraju Avi
V Comini Lara
V Feo Carlo
V Marino Marco
V Shaw Abigail
V\ue1zquez- Fern\ue1ndez Andrea
Vaccarella (Azienda Ospedaliera Gianpaolo
Valdes- Hernandez Javier
Valsecchi Luca
Vashisht Rajiv
VCO) Asl
Venkatesan (Glan Clwyd Hospital) Gowtham
Vera-Mansilla Cristina
Vergari (Ospedali Riuniti di Ancona) Roberto
Vescio (University 'Magna Graecia' of Catanzaro) Giuseppina
Vidya Raghavan
Vieira (Centro Hospital Universit\ue1rio S\ue3oJo\ue3o) Paula
Vijay Vardhini
Vimalachandran Dale
Vimalachandran Dale
Violante Tommaso
Vovola Fernanda
Vulliamy Paul
W Endorf (Hennepin Healthcare) Frederick
W Etchill Eric
W L\uf6ffler Markus
W L\uf6ffler Markus
Wall Rosemary
Wallwork Kate
Ward Alex
Warwick (University Hospital Southampton) David
Waseem Saima
Weaver Helen
Wells Fiona
Wen Jiaxin
West Raha
Whitehall Emma
Wild Laura
Wilkins Alex
Williams Gethin
Williams Matthew
Winnand (University Hospital Aachen) Philipp
Wong (Addenbrooke's Hospital) Ken
Worku (Queen\u2019s Medical Centre Dawit
Wright Naomi
WS Ho (Leeds Teaching Hospitals NHS Trust Michael
WT Ngu Albert
y Cajal) Cristina Cerro (Hospital Universitario Ram\uf3n
Y Oo (Department of Cardiothoracic Surgery Aung
y Polit\ue9cnico La Fe) Blas Flor (Hospital Universitario
Y van der Plas Willemijn
Yalamanchili Seema
Yershov (South Warwickshire NHS Foundation Trust) Danylo
Young Richard
Yousra Ahmed (Portsmouth Hospital NHS Trust) Simon Toh
Yurttas Can
Zadegan Frederic
Zafar (Northwick Park Hospital) Noman
Zakaria Rasheed
Zambon Martina
Zanini Nicola
ZE Durst Alexander
Zerbib Philippe
Zonta (Ospedale San Biagio Sandro
Publication venue: 'Elsevier BV'
Publication date: 01/01/2020
Field of study

Background: The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on postoperative recovery needs to be understood to inform clinical decision making during and after the COVID-19 pandemic. This study reports 30-day mortality and pulmonary complication rates in patients with perioperative SARS-CoV-2 infection. Methods: This international, multicentre, cohort study at 235 hospitals in 24 countries included all patients undergoing surgery who had SARS-CoV-2 infection confirmed within 7 days before or 30 days after surgery. The primary outcome measure was 30-day postoperative mortality and was assessed in all enrolled patients. The main secondary outcome measure was pulmonary complications, defined as pneumonia, acute respiratory distress syndrome, or unexpected postoperative ventilation. Findings: This analysis includes 1128 patients who had surgery between Jan 1 and March 31, 2020, of whom 835 (74·0%) had emergency surgery and 280 (24·8%) had elective surgery. SARS-CoV-2 infection was confirmed preoperatively in 294 (26·1%) patients. 30-day mortality was 23·8% (268 of 1128). Pulmonary complications occurred in 577 (51·2%) of 1128 patients; 30-day mortality in these patients was 38·0% (219 of 577), accounting for 81·7% (219 of 268) of all deaths. In adjusted analyses, 30-day mortality was associated with male sex (odds ratio 1·75 [95% CI 1·28–2·40], p\textless0·0001), age 70 years or older versus younger than 70 years (2·30 [1·65–3·22], p\textless0·0001), American Society of Anesthesiologists grades 3–5 versus grades 1–2 (2·35 [1·57–3·53], p\textless0·0001), malignant versus benign or obstetric diagnosis (1·55 [1·01–2·39], p=0·046), emergency versus elective surgery (1·67 [1·06–2·63], p=0·026), and major versus minor surgery (1·52 [1·01–2·31], p=0·047). Interpretation: Postoperative pulmonary complications occur in half of patients with perioperative SARS-CoV-2 infection and are associated with high mortality. Thresholds for surgery during the COVID-19 pandemic should be higher than during normal practice, particularly in men aged 70 years and older. Consideration should be given for postponing non-urgent procedures and promoting non-operative treatment to delay or avoid the need for surgery. Funding: National Institute for Health Research (NIHR), Association of Coloproctology of Great Britain and Ireland, Bowel and Cancer Research, Bowel Disease Research Foundation, Association of Upper Gastrointestinal Surgeons, British Association of Surgical Oncology, British Gynaecological Cancer Society, European Society of Coloproctology, NIHR Academy, Sarcoma UK, Vascular Society for Great Britain and Ireland, and Yorkshire Cancer Research

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Pancreatic surgery outcomes: multicentre prospective snapshot study in 67 countries

Author: ?tinas A
Aalem HAA
Ababneh H
Abbas A
Abbas A
Abbas H
Abbasi A
Abbassi F
Abbasy J
Abbood AH
Abboud K
Abdallah A
Abdalsalam SJA
Abdelaal A
Abdelalemm M
Abdelhafez MHZ
Abdelhalim K
Abdeljalil M
Abdelkarem M
Abdelmageed A
Abdelmageed A
Abdelmaksoud M
Abdelmawgoud S
Abdelmawla M
Abdelmawla MOMK
Abdelmoneim N
Abdelnoor A
Abdelrahman F
Abdelrazek HA
Abdelrhman R
Abdelzaher A
Abdelzaher AT
Abdou K
Abdoun M
Abdualqader M
Abdualqader MYM
Abdulhaq A
Abduljawad H
Abdullaev A
Abdullah NAN
Abdulmonem A
Abdulwahed E
Abebrese J
Abiyere H
Abobakr AM
Aboelfath S
Abosamak NE
Abu Harb Z
Abu Hilal M
Abu Hilal M
Abu Jayyab M
Abu-Elfatth AM
Abu-Ghazal S
Abu-Ghazal SY
Abuali ASAME
Abuelazm M
Abuelnaga Y
Abuelnaga Y
Abughazal SY
Abuleil A
Abusannuga M
Abuzaina K
Adam I
Aday U
Adeyeye A
Adeyeye NA
Adham M
Adhikari KM
Affary AA
Afzal A
Afzal I
Aghdassi A
Ahmadi BE
Ahmed EA
Ahmed MBE
Ahmed R
Ahmeed
Ajayi P
Akahoshi K
Akbar A
Akhtar N
Al-Abdi R
Al-Abed O
Al-Ameri S
Al-Ameri SAAS
Al-Asadi MAMM
Al-Dowsh NA
Al-Eryani F
Al-Faiq S
Al-Haj A
Al-Hyari A
Al-Isawi A
Al-juaifari MA
Al-Khawlani Q
Al-Kubati W
Al-Maadani B
Al-Mallah R
Al-Markiz E
Al-Mekhlafi A
Al-Melhani W
Al-Naggar H
Al-Naggar H
Al-Ogaili M
Al-Qasrawi S
Al-Saban R
Al-saban RAM
Al-Sader MA-J
Al-Samawi A
Al-Samawi H
Al-Sarireh B
Al-Shami K
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Al-sharabi EAE
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Al-Tekreeti S
Alahmed F
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Alegria CR
Alfano MS
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Aljaber A
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Alkhaleel W
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Allam A
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Brustia R
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Capitanich P
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Carganico G
Carino NDL
Carr-Boyd P
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Catrina E
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Cereda M
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Chand JT
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Chardalias L
Chardarov N
Chasiotis D
Chattopadhyay S
Chaturvedi A
Chatzialis I
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Štironja I
Publication venue
Publication date: 18/01/2024
Field of study

Queen Mary Research Online

Effect of COVID-19 pandemic lockdowns on planned cancer surgery for 15 tumour types in 61 countries: an international, prospective, cohort study

Author: Ababneh H.
Abadia M.
Abate E.
Abatini C.
Abbas A. M.
Abbott Tom E. F.
Abd Elazeem H. A. S.
Abd-Elkariem A. Y.
Abd-elsalam S.
Abdallah E. A.
Abdel Jalil R.
Abdel Al S.
Abdeldayem H.
Abdelkabir M.
Abdelkader Salama, I
Abdelkarem M. M.
Abdelmajeed A.
Abdelrahman A.
Abdelsamed A.
Abdou M.
Abdul Maei N.
Abdulwahed E.
Abeloos J.
Abosamak N. E.
Abou Chaar M. K.
Abou-Khalil J.
Aboulkassem H.
Abu Za'nouneh F. J.
Abudher A.
Abukhalaf Sadi
Abusannoga M.
Acosta J.
Adamina Michel
Adamoli L.
Ademuyiwa Adesoji
Ademuyiwa Adesoji O.
Adisa Adewale
Agarwal A.
Agarwal Arnav
Agarwal P.
Agarwal S. P.
Agarwal V
Aggarwal G.
Aggarwal M.
Agnes A.
Agostini C.
Agrawal A.
Agrawal N.
Agrawal V
Agresta F.
Aguiar Junior S.
Aguzzoli L.
Ahluwalia P.
Ahmed A.
Ahmed R.
Ahmed Z.
Ahn J. H.
Aime A.
Akhtar N.
Akkulak Murat
Akmenkalne L.
Akrivou D.
Akula A. K.
Al Abdallah M.
Al Riyami S.
AL Sayed M.
Al-Masri M.
Al-Najjar H.
Al-Shraideh A. A.
Alaa S.
Alakaloko Felix
Alam N.
AlAmeer Ehab
Alameer Ehab
Alamri Alex
Alansari S. A. A.
Alawami A.
Alawami M.
Alawneh F.
Alazawi D.
Albashri M.
Albertsmeier M.
Albertsmeier Markus
Aldayri Z.
Alderson Derek
Aldokali N.
Alemanno G.
Alexoudi V
Alfieri S.
Algallai M.
Ali A.
Allemand C.
Almahmeed H.
Almazeedi S.
Almeciga A.
Almeciga A.
Almezghwi H.
Almond Max
Alrahawy M.
Alsabah S.
Alsaraireh O.
Alser Osaid
Alshaar Muhammad
Alshareea E.
Alshareef K.
Alshryda Sattar
Alsoufi A.
Altomare D. F.
Altomi I
Altoumi M.
Alurralde C.
Alwarfly S.
Alzaede S.
Ambre S.
Amin Sahid N.
Amira G.
Amo-Antwi K.
Ampollini L.
Anania G.
Anastasi A.
Anastasio J.
Andreani L.
Angel Aristizabal J.
Angele M.
Angelou K.
Annessi V
Annicchiarico A.
Ansarin M.
Anthoulakis C.
Anthuber M.
Antonakis P.
Antonelli B.
Antoniades K.
Antonopoulou M., I
Antony S.
Apas Perez de Nucci A.
Appiah-kubi A.
Aprile A.
Aquila F.
Arcuri M. F.
Aremu M.
Arias-Amezquita F.
Aribi N.
Aribi S.
Arkadopoulos N.
Armao T.
Armatura G.
Arminio A.
Arnaud A. P.
Arnaud Alexis P.
Arnaud Alexis P.
Arora A.
Arora R. K.
Arslan K.
Ashoush F.
Ashraf M.
Asti E. L. G.
Astreidis I
Ataide Gomes Gustavo Mendonca
Athanasakis E.
Atta R.
Attia D.
Augestad Knut Magne
Aversano A.
Avlund T.
Ayasra F.
Ayasra Faris
Ayasra Faris
Ayasra Y.
Ayman A.
Azevedo Jose
Azevedo Jose
Aziz G.
Azizeldine M. G.
Azzam A. Y.
Bacic G.
Bacic I
Badalamenti G.
Badellino E.
Badr H.
Badra R.
Badwe R. A.
Baghel A.
Bagraith K.
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Publication venue: 'Elsevier BV'
Publication date: 01/01/2021
Field of study

Background: Surgery is the main modality of cure for solid cancers and was prioritised to continue during COVID-19 outbreaks. This study aimed to identify immediate areas for system strengthening by comparing the delivery of elective cancer surgery during the COVID-19 pandemic in periods of lockdown versus light restriction. Methods: This international, prospective, cohort study enrolled 20 006 adult (≥18 years) patients from 466 hospitals in 61 countries with 15 cancer types, who had a decision for curative surgery during the COVID-19 pandemic and were followed up until the point of surgery or cessation of follow-up (Aug 31, 2020). Average national Oxford COVID-19 Stringency Index scores were calculated to define the government response to COVID-19 for each patient for the period they awaited surgery, and classified into light restrictions (index <20), moderate lockdowns (20–60), and full lockdowns (>60). The primary outcome was the non-operation rate (defined as the proportion of patients who did not undergo planned surgery). Cox proportional-hazards regression models were used to explore the associations between lockdowns and non-operation. Intervals from diagnosis to surgery were compared across COVID-19 government response index groups. This study was registered at ClinicalTrials.gov, NCT04384926. Findings: Of eligible patients awaiting surgery, 2003 (10·0%) of 20 006 did not receive surgery after a median follow-up of 23 weeks (IQR 16–30), all of whom had a COVID-19-related reason given for non-operation. Light restrictions were associated with a 0·6% non-operation rate (26 of 4521), moderate lockdowns with a 5·5% rate (201 of 3646; adjusted hazard ratio [HR] 0·81, 95% CI 0·77–0·84; p<0·0001), and full lockdowns with a 15·0% rate (1775 of 11 827; HR 0·51, 0·50–0·53; p<0·0001). In sensitivity analyses, including adjustment for SARS-CoV-2 case notification rates, moderate lockdowns (HR 0·84, 95% CI 0·80–0·88; p<0·001), and full lockdowns (0·57, 0·54–0·60; p<0·001), remained independently associated with non-operation. Surgery beyond 12 weeks from diagnosis in patients without neoadjuvant therapy increased during lockdowns (374 [9·1%] of 4521 in light restrictions, 317 [10·4%] of 3646 in moderate lockdowns, 2001 [23·8%] of 11 827 in full lockdowns), although there were no differences in resectability rates observed with longer delays. Interpretation: Cancer surgery systems worldwide were fragile to lockdowns, with one in seven patients who were in regions with full lockdowns not undergoing planned surgery and experiencing longer preoperative delays. Although short-term oncological outcomes were not compromised in those selected for surgery, delays and non-operations might lead to long-term reductions in survival. During current and future periods of societal restriction, the resilience of elective surgery systems requires strengthening, which might include protected elective surgical pathways and long-term investment in surge capacity for acute care during public health emergencies to protect elective staff and services. Funding: National Institute for Health Research Global Health Research Unit, Association of Coloproctology of Great Britain and Ireland, Bowel and Cancer Research, Bowel Disease Research Foundation, Association of Upper Gastrointestinal Surgeons, British Association of Surgical Oncology, British Gynaecological Cancer Society, European Society of Coloproctology, Medtronic, Sarcoma UK, The Urology Foundation, Vascular Society for Great Britain and Ireland, and Yorkshire Cancer Research

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Machine learning risk prediction of mortality for patients undergoing surgery with perioperative SARS-CoV-2: the COVIDSurg mortality score

Author: A A Adeniyi
A A Albaroudi
A A Ali Karar
A A Apampa
A A B Jamjoom
A A Carvalho
A A Islam
A A Kerawala
A A Marra
A A Ogunyemi
A A Okunowo
A A Schnitzbauer
A A Singh
A A W Van Geloven
A Abad-Gurumeta
A Abad-Motos
A Abbas
A Abbasov
A Abdelmajeed
A Abdelrahman
A Abdelsamed
A Abelevich
A Aboelkassem ibrahim
A Abood
A Abouassi
A Abrate
A Abreu da Silva
A Abuown
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AD Bueno Cañones
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Alaa El-Hussuna
Alarabi A
Alexis Arnaud
Alexis P Arnaud
Amanpreet Brar
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Anant Desai
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Andreas Karwath
Andrew Schache
Andrey Litvin
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Aneel Bhangu
Angelos Kolias
Antonio Ramos de la Madina
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April Roslani
Arben Gjata
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Arnav Agarwal
Arnav Agarwal
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Babatunde Osinaike
Brett E Dawson
Brittany Kendall
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Chetan Khatri
Chew Min Hoe
Christina Fotopoulou
Conor S Jones
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Dakshitha Wickramasinghe
Dale Vimalchandran
Daniel Cox
Daniel Wettstein
Daoud Chaudhry
Dejan Radenkovic
Dennis Mazingi
Dennis Mazingi
Dhruv Ghosh
Dmitri Nepogodiev
Dmitri Nepogodiev
Dmitri Nepogodiev
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E Ang
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E Barret
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E Britton
E Brunocilla
E C Gundogdu
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E Cordova-Calle
E Cotte
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E Dainius
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E Dauer
E Davies
E De Crescenzo
E Dikicier
E Duchalais
E Duck
E Díez
E E Ali
E E Estrada
E E Sosa-Duran
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L Brown
L Burdine
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L Cruz
L D Cato
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L Duggleby
L E Pérez-Sánchez
L Elliott
L Fernandez-Vega
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L Findlay
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L Gordini
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L Guzmán
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L Hansen
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L Hitchman
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L J Rogers
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L Loutzidou
L Luke
L Luo
L M Lopes
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L Zier
Laura Bravo
Laura Bravo
Laura Bravo
Laura Martinez
Leah Argus
Lisa Norman
Luis Boccalatte
Luke Slater
Luke Slater
M A Acosta Mérida
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M D C De Miguel-Ardevines
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M E Alexander
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M Ho
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M Holscher
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M I Prieto Nieto
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M Inama
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M Ip
M Ismail
M J Amaral
M J Hill
M J Irarrázaval
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M J Teixeira
M J W van der Oest
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M L Collins
M L Fernandez
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M L JÖnsson
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M Lee
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M M Carvello
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M P Callahan
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M S A T Fathelbab
M S Araujo
M S Babar
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M S Greenhalgh
M S J Wilson
M S M Omar
M S Masood
M S Morsy
M S Qatora
M S Santero-Ramirez
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M S Tamimy
M S Thet
M Sait
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M SalÖ
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M Stoliarov
M Sund
M Sundhu
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M Sánchez-Rubio
M T Fayed
M T Fernández Martín
M T Gavaldà Pellicé
M T Gonzalez-Nicolas-Trebol
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M T Montella
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M Thomas
M Thornhill
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M Toledano
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M Trejo-Avila
M Tulbah
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M U Younis
M Uittenbogaart
M Ujiki
M Umair
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M V Marino
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M Van Heinsbergen
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M Vatish
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M W Benjamin
M W LÖffler
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M Y Oudrhiri
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M Zizzo
Malin Sund
Marco Fiore
Maria Aguilera Lorena
Maria Marta Modolo
Maria Marta Modolo
Maria Picciochi
Maria Picciochi
Maricarmen Olivos
Marie Dione Parreno-Sacdalan
Markus Albertsmeiers
Markus Loffler
Martin Rutegård
Mary L Venn
Mary Venn
Masoud Mozafari
Mengistu Gebreyohanes Mengesha
Michael D Jenkinson
Miguel Cunha
Mihail Slavchev
Milou Noltes
Mohammad Chaar
Mohammad Jamal
Mohammad Khosravi
Mohammed Elmujtaba
Moises Cukier
Muhammad Gohar
Muhammed Elhadi
Muhammed Elhadi
Mustafa Abu Mohsen Daraghmeh
N A Che Bakri
N A Gemelli
N A Hacim
N A M Dekker
N A Sheikh
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N Adeleke
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N B Jamieson
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N E Abosamak
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N N Abd Kahar
N N Dudi-Venkata
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N P Hardy
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N Vassos
N Yassin
N Z Utkan
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N Zanini
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N Zeller
Naomi Wright
Ncamsile Nhlabathi
Neil Smart
null null
O A Elebute
O A Omisanjo
O A Oshodi
O A Oyelakin
O Agodirin
O Alamri
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O Asodisen
O Atoyebi
O B F Risk
O Babawale
O Bajomo
O Barbier
O Bloom
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O Brown
O Brown
O Budha Magar
O C Tatar
O Cano
O Costerousse
O Cullivan
O Dwidar
O E Posadas-Trujillo
O Emmerson
O Ersen
O Esteban Sinovas
O F Babalola
O Flannery
O Fuwa
O G Akaba
O G Nwaorgu
O García Villar
O Gil-Albarova
O Glehen
O Guevara
O H Abiyere
O Habeeb
O Hamad
O Ioannidis
O ismail
O Izquierdo
O J Baker
O Karaaslan
O Kollmar
O Koukoura
O L Serevina
O Lusawana
O Lyons
O M Faboya
O M Taylor
O M Williams
O Malard
O Martin-Sole
O Mateo-Sierra
O Merzlikin
O N Tucker
O Nogueira
O O Banjo
O Ogundoyin
O Olasehinde
O Oyende
O P Vaz
O Pathmanaban
O Rominiyi
O Ryska
O S Santonocito
O Sogair
O Steinmetz
O Steinmetz
O T Adeyemo
O Usman
O Verdonck
O Warren
O Williams
O Yalkın
O Zmora
Oded Zmora
Omar M Omar
Osaid Alser
Oumaima Outani
P A Bouche
P A Cabrera
P A Carroll
P Agoston
P Alonso Ortuño
P Ameerally
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P G Teixeira
P G Vaughan-Shaw
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P Guerreiro
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P H E Teeuwen
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P HÖhn
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P S Nischwitz
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P V Fernández-Fernández
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P W H E Vriens
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P Winnand
P Y Tint
P Yesantharao
P Zarubenko
P Zerbib
Pascal Jonker
Peiman Brouk
Peter Christensen
Peter Hutchinson
Peter Pockney
Philip Townend
Pieter Steinkamp
Piotr Major
Q Ballouhey
Q M Nunes
R A Ramos
R A Rollett
R A Salcedo-Hernández
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R Aftab
R Al Raddadi
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R Grolman
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R Guevara
R H Sayyed
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Vidya Raghavan
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W* Biffl
Willemijn van der Plas
William Jebril
X Cathelineau
X Jimenez Villanueva
X L Griffin
X Luo
X Morales
X P Vasquez-Ojeda
X S Tan
X Tarrado
Ximena Vasquez
XXX Kubyshkin
Y A Oshodi
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Y W Smart
Y Ying
Y Yousef
Y Zhang
Z Abual-Rub
Z Aliyeva
Z Ang
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Z Cooper
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Z Hamady
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Z Jawad
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Zainab Al Balushi
à Fernández Camuñas
à Pascual
é J Ryan
Publication venue: Oxford University Press (OUP)
Publication date: 06/07/2021
Field of study

To support the global restart of elective surgery, data from an international prospective cohort study of 8492 patients (69 countries) was analysed using artificial intelligence (machine learning techniques) to develop a predictive score for mortality in surgical patients with SARS-CoV-2. We found that patient rather than operation factors were the best predictors and used these to create the COVIDsurg Mortality Score (https://covidsurgrisk.app). Our data demonstrates that it is safe to restart a wide range of surgical services for selected patients.</jats:p

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