88 research outputs found
Isotropization of Bianchi type models and a new FRW solution in Brans-Dicke theory
Using scaled variables we are able to integrate an equation valid for
isotropic and anisotropic Bianchi type I, V, IX models in Brans-Dicke (BD)
theory. We analyze known and new solutions for these models in relation with
the possibility that anisotropic models asymptotically isotropize, and/or
possess inflationary properties. In particular, a new solution of curve
() Friedmann-Robertson-Walker (FRW) cosmologies in Brans-Dicke theory
is analyzed.Comment: 15 pages, 4 postscript figures, to appear in Gen. Rel. Grav., special
issue dedicated in honour of Prof. H. Dehne
Isotropization of Bianchi-Type Cosmological Solutions in Brans-Dicke Theory
The cosmic, general analitic solutions of the Brans--Dicke Theory for the
flat space of homogeneous and isotropic models containing perfect, barotropic,
fluids are seen to belong to a wider class of solutions --which includes
cosmological models with the open and the closed spaces of the
Friedmann--Robertson--Walker metric, as well as solutions for models with
homogeneous but anisotropic spaces corresponding to the Bianchi--Type metric
clasification-- when all these solutions are expressed in terms of reduced
variables. The existence of such a class lies in the fact that the scalar
field, , times a function of the mean scale factor or ``volume element'',
, which depends on time and on the barotropic index of the
equation of state used, can be written as a function of a ``cosmic time''
reduced in terms of another function of the mean scale factor depending itself
again on the barotropic index but independent of the metrics here employed.
This reduction procedure permites one to analyze if explicitly given
anisotropic cosmological solutions ``isotropize'' in the course of their time
evolution. For if so can happen, it could be claimed that there exists a
subclass of solutions that is stable under anisotropic perturbations.Comment: 15 pages, Late
Propensity-matched analysis of patient-reported outcomes for neoadjuvant chemotherapy prior to radical cystectomy
© 2019, Springer-Verlag GmbH Germany, part of Springer Nature. Purpose: To evaluate patient-reported outcomes (PROs) for bladder cancer patients undergoing neoadjuvant chemotherapy (NAC) prior to radical cystectomy (RC) using longitudinal data and propensity-matched scoring analyses. Methods: 155 patients with muscle-invasive bladder cancer scheduled for RC completed the European Organization for Research and Treatment of Cancer questionnaires, EORTC QLQ-C30, EORTC QLQ-BLM30, Fear of Recurrence Scale, Mental Health Inventory and Satisfaction with Life Scale within 4 weeks of surgery. A propensity-matched analysis was performed comparing pre-surgery PROs among 101 patients who completed NAC versus 54 patients who did not receive NAC. We also compared PROs pre- and post-chemotherapy for 16 patients who had data available for both time points. Results: In propensity-matched analysis, NAC-treated patients reported better emotional and sexual function, mental health, urinary function and fewer financial concerns compared to those that did not receive NAC. Longitudinal analysis showed increases in fatigue, nausea and appetite loss following chemotherapy. Conclusion: Propensity-matched analysis did not demonstrate a negative effect of NAC on PRO. Several positive associations of NAC were found in the propensity-matched analysis, possibly due to other confounding differences between the two groups or actual clinical benefit. Longitudinal analysis of a small number of patients found small to modest detrimental effects from NAC similar to toxicities previously reported. Our preliminary findings, along with known survival and toxicity data, should be considered in decision-making for NAC
Betel quid dependence is associated with functional connectivity changes of the anterior cingulate cortex: a resting-state fMRI study
Role of Appetite-Regulating Peptides in the Pathophysiology of Addiction: Implications for Pharmacotherapy
" Les fragments de Jumièges. La découverte "
Catalogue d'exposition : Le vitrail. Chefs d'œuvre cachés du Musée, Musée des Antiquités de la Seine-Maritime, Rouen, Conseil Général de la Seine-Maritim
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