Partycypacja obywateli w polityce rozwoju śląskich miast

The issue of inhabitants’ participation in policy making is becoming more and more important in the practice of Polish cities. It should be noted, however, that the undertaken initiatives can be both optional or resulting from the national regulations. Therefore the experience of different cities in terms of citizen involvement and empowerment of the process of local development are very diverse. In order to promote good practices we need to systematize knowledge relating to the topic in question. We also need to analyze strategic documents elaborated by cities and initiatives realized in practice. The article aims – at least partially – to fill in the gap existing in the presented scientific field, based on examples from the region of Silesia. It focuses on civic participation in the local policy in selected Silesian cities: Rybnik, Czestochowa and Dabrowa Górnicza.  Zagadnienie partycypacji mieszkańców nabiera na znaczeniu w praktyce działania polskich miast. Należy jednak zauważyć, że podejmowane inicjatywy w tym zakresie mogą mieć charakter fakultatywny bądź wynikający z regulacji ogólnokrajowych. Doświadczenia poszczególnych ośrodków miejskich w kierunku angażowania mieszkańców i uspołecznienia procesu rozwoju lokalnego są zatem bardzo zróżnicowane. W celu propagowania dobrych praktyk niezbędne jest usystematyzowanie wiedzy w przedmiotowym obszarze badań oraz diagnoza dokumentów strategicznych poszczególnych samorządów i realizowanych inicjatyw w praktyce. Artykuł ma na celu przynajmniej częściowe wypełnienie luki w przedstawionym obszarze badawczym, zawężając perspektywę badawcza do granic administracyjnych województwa śląskiego. Zaprezentowano w nim znaczenie partycypacji obywatelskiej w polityce lokalnej, odwołując sie do praktyk wybranych śląskich miast: Rybnika, Częstochowy oraz Dąbrowy Górniczej. &nbsp

Partycypacja obywateli w polityce rozwoju śląskich miast

The issue of inhabitants’ participation in policy making is becoming more and more important in the practice of Polish cities. It should be noted, however, that the undertaken initiatives can be both optional or resulting from the national regulations. Therefore the experience of different cities in terms of citizen involvement and empowerment of the process of local development are very diverse. In order to promote good practices we need to systematize knowledge relating to the topic in question. We also need to analyze strategic documents elaborated by cities and initiatives realized in practice. The article aims – at least partially – to fill in the gap existing in the presented scientific field, based on examples from the region of Silesia. It focuses on civic participation in the local policy in selected Silesian cities: Rybnik, Czestochowa and Dabrowa Górnicza.  Zagadnienie partycypacji mieszkańców nabiera na znaczeniu w praktyce działania polskich miast. Należy jednak zauważyć, że podejmowane inicjatywy w tym zakresie mogą mieć charakter fakultatywny bądź wynikający z regulacji ogólnokrajowych. Doświadczenia poszczególnych ośrodków miejskich w kierunku angażowania mieszkańców i uspołecznienia procesu rozwoju lokalnego są zatem bardzo zróżnicowane. W celu propagowania dobrych praktyk niezbędne jest usystematyzowanie wiedzy w przedmiotowym obszarze badań oraz diagnoza dokumentów strategicznych poszczególnych samorządów i realizowanych inicjatyw w praktyce. Artykuł ma na celu przynajmniej częściowe wypełnienie luki w przedstawionym obszarze badawczym, zawężając perspektywę badawcza do granic administracyjnych województwa śląskiego. Zaprezentowano w nim znaczenie partycypacji obywatelskiej w polityce lokalnej, odwołując sie do praktyk wybranych śląskich miast: Rybnika, Częstochowy oraz Dąbrowy Górniczej. &nbsp

Health related quality of life in patients with diabetic foot ulceration — translation and Polish adaptation of Diabetic Foot Ulcer Scale short form

Differential item functioning (DIF) detection. (DOCX 14 kb

Nuclear Magnetic Resonance Solution Structure and Functional Behavior of the Human Proton Channel

The human voltage-gated proton channel [Hv1(1) or VSDO(2)] plays an important role in the human innate immune system. Its structure differs considerably from those of other cation channels. It is built solely of a voltage-sensing domain and thus lacks the central pore domain, which is essential for other cation channels. Here, we determined the solution structure of an N- and C-terminally truncated human Hv1 (Δ-Hv1) in the resting state by nuclear magnetic resonance (NMR) spectroscopy. Δ-Hv1 comprises the typical voltage-sensing antiparallel four-helix bundle (S1–S4) preceded by an amphipathic helix (S0). The solution structure corresponds to an intermediate state between resting and activated forms of voltage-sensing domains. Furthermore, Zn2+-induced closing of proton channel Δ-Hv1 was studied with two-dimensional NMR spectroscopy, which showed that characteristic large scale dynamics of open Δ-Hv1 are absent in the closed state of the channel. Additionally, pH titration studies demonstrated that a higher H+ concentration is required for the protonation of side chains in the Zn2+-induced closed state than in the open state. These observations demonstrate both structural and dynamical changes involved in the process of voltage gating of the Hv1 channel and, in the future, may help to explain the unique properties of unidirectional conductance and the exceptional ion selectivity of the channel

Comparing Breast Cancer Multiparameter Tests in the OPTIMA Prelim Trial: No Test Is More Equal Than the Others

Background: Previous reports identifying discordance between multiparameter tests at the individual patient level have been largely attributed to methodological shortcomings of multiple in silico studies. Comparisons between tests, when performed using actual diagnostic assays, have been predicted to demonstrate high degrees of concordance. OPTIMA prelim compared predicted risk stratification and subtype classification of different multiparameter tests performed directly on the same population. Methods: Three hundred thirteen women with early breast cancer were randomized to standard (chemotherapy and endocrine therapy) or test-directed (chemotherapy if Oncotype DX recurrence score >25) treatment. Risk stratification was also determined with Prosigna (PAM50), MammaPrint, MammaTyper, NexCourse Breast (IHC4-AQUA), and conventional IHC4 (IHC4). Subtype classification was provided by Blueprint, MammaTyper, and Prosigna. Results: Oncotype DX predicted a higher proportion of tumors as low risk (82.1%, 95% confidence interval [CI] = 77.8% to 86.4%) than were predicted low/intermediate risk using Prosigna (65.5%, 95% CI = 60.1% to 70.9%), IHC4 (72.0%, 95% CI = 66.5% to 77.5%), MammaPrint (61.4%, 95% CI = 55.9% to 66.9%), or NexCourse Breast (61.6%, 95% CI = 55.8% to 67.4%). Strikingly, the five tests showed only modest agreement when dichotomizing results between high vs low/intermediate risk. Only 119 (39.4%) tumors were classified uniformly as either low/intermediate risk or high risk, and 183 (60.6%) were assigned to different risk categories by different tests, although 94 (31.1%) showed agreement between four of five tests. All three subtype tests assigned 59.5% to 62.4% of tumors to luminal A subtype, but only 121 (40.1%) were classified as luminal A by all three tests and only 58 (19.2%) were uniformly assigned as nonluminal A. Discordant subtyping was observed in 123 (40.7%) tumors. Conclusions: Existing evidence on the comparative prognostic information provided by different tests suggests that current multiparameter tests provide broadly equivalent risk information for the population of women with estrogen receptor (ER)–positive breast cancers. However, for the individual patient, tests may provide differing risk categorization and subtype information

Penilaian Kinerja Keuangan Koperasi di Kabupaten Pelalawan

This paper describe development and financial performance of cooperative in District Pelalawan among 2007 - 2008. Studies on primary and secondary cooperative in 12 sub-districts. Method in this stady use performance measuring of productivity, efficiency, growth, liquidity, and solvability of cooperative. Productivity of cooperative in Pelalawan was highly but efficiency still low. Profit and income were highly, even liquidity of cooperative very high, and solvability was good

Juxtaposing BTE and ATE – on the role of the European insurance industry in funding civil litigation

One of the ways in which legal services are financed, and indeed shaped, is through private insurance arrangement. Two contrasting types of legal expenses insurance contracts (LEI) seem to dominate in Europe: before the event (BTE) and after the event (ATE) legal expenses insurance. Notwithstanding institutional differences between different legal systems, BTE and ATE insurance arrangements may be instrumental if government policy is geared towards strengthening a market-oriented system of financing access to justice for individuals and business. At the same time, emphasizing the role of a private industry as a keeper of the gates to justice raises issues of accountability and transparency, not readily reconcilable with demands of competition. Moreover, multiple actors (clients, lawyers, courts, insurers) are involved, causing behavioural dynamics which are not easily predicted or influenced. Against this background, this paper looks into BTE and ATE arrangements by analysing the particularities of BTE and ATE arrangements currently available in some European jurisdictions and by painting a picture of their respective markets and legal contexts. This allows for some reflection on the performance of BTE and ATE providers as both financiers and keepers. Two issues emerge from the analysis that are worthy of some further reflection. Firstly, there is the problematic long-term sustainability of some ATE products. Secondly, the challenges faced by policymakers that would like to nudge consumers into voluntarily taking out BTE LEI

Search for stop and higgsino production using diphoton Higgs boson decays

Results are presented of a search for a "natural" supersymmetry scenario with gauge mediated symmetry breaking. It is assumed that only the supersymmetric partners of the top-quark (stop) and the Higgs boson (higgsino) are accessible. Events are examined in which there are two photons forming a Higgs boson candidate, and at least two b-quark jets. In 19.7 inverse femtobarns of proton-proton collision data at sqrt(s) = 8 TeV, recorded in the CMS experiment, no evidence of a signal is found and lower limits at the 95% confidence level are set, excluding the stop mass below 360 to 410 GeV, depending on the higgsino mass