180 research outputs found
DIRECTION OF ISOMETRIC BALLISTIC FORCE IS RELATED TO ANTAGONISTIC MUSCULE DISCHARGE
The purpose of this study was to investigate the relationship between electromyographic (EMG) activities of human thigh muscles (vastus medialis, vastus lateralis, rectus femoris, biceps femoris and semitendinosus) and the direction of knee extension force during ramp and ballistic contractions. Four subjects exerted isometric knee extension forces at a target force level of 40% of maximum voluntary contraction (MVC) at various speeds. Variations of EMG amplitudes of all thigh muscles during ballistic contraction were much larger than those during ramp contractions. Only biceps femoris was related to the direction of force. These results suggest that EMG activity of biceps femoris muscle is an important factor for deciding direction of isometric ballistic knee extension force
An Electron-Tracking Compton Telescope for a Survey of the Deep Universe by MeV gamma-rays
Photon imaging for MeV gammas has serious difficulties due to huge
backgrounds and unclearness in images, which are originated from incompleteness
in determining the physical parameters of Compton scattering in detection,
e.g., lack of the directional information of the recoil electrons. The recent
major mission/instrument in the MeV band, Compton Gamma Ray
Observatory/COMPTEL, which was Compton Camera (CC), detected mere
persistent sources. It is in stark contrast with 2000 sources in the GeV
band. Here we report the performance of an Electron-Tracking Compton Camera
(ETCC), and prove that it has a good potential to break through this stagnation
in MeV gamma-ray astronomy. The ETCC provides all the parameters of
Compton-scattering by measuring 3-D recoil electron tracks; then the Scatter
Plane Deviation (SPD) lost in CCs is recovered. The energy loss rate (dE/dx),
which CCs cannot measure, is also obtained, and is found to be indeed helpful
to reduce the background under conditions similar to space. Accordingly the
significance in gamma detection is improved severalfold. On the other hand, SPD
is essential to determine the point-spread function (PSF) quantitatively. The
SPD resolution is improved close to the theoretical limit for multiple
scattering of recoil electrons. With such a well-determined PSF, we demonstrate
for the first time that it is possible to provide reliable sensitivity in
Compton imaging without utilizing an optimization algorithm. As such, this
study highlights the fundamental weak-points of CCs. In contrast we demonstrate
the possibility of ETCC reaching the sensitivity below erg
cm s at 1 MeV.Comment: 19 pages, 12 figures, Accepted to the Astrophysical Journa
CANGAROO-III Observation of TeV Gamma Rays from the vicinity of PSR B1 706-44
Observation by the CANGAROO-III stereoscopic system of the Imaging Cherenkov
Telescope has detected extended emission of TeV gamma rays in the vicinity of
the pulsar PSR B170644. The strength of the signal observed as
gamma-ray-like events varies when we apply different ways of emulating
background events. The reason for such uncertainties is argued in relevance to
gamma-rays embedded in the "off-source data", that is, unknown sources and
diffuse emission in the Galactic plane, namely, the existence of a complex
structure of TeV gamma-ray emission around PSR B170644.Comment: 10 pages, 13 figures, to be published in Ap
CANGAROO-III observation of TeV gamma rays from the unidentified gamma-ray source HESS J1614-518
We report the detection, with the CANGAROO-III imaging atmospheric Cherenkov
telescope array, of a very high energy gamma-ray signal from the unidentified
gamma-ray source HESS J1614-518, which was discovered in the H.E.S.S. Galactic
plane survey. Diffuse gamma-ray emission was detected above 760 GeV at the 8.9
sigma level during an effective exposure of 54 hr from 2008 May to August. The
spectrum can be represented by a power-law:
8.2+-2.2_{stat}+-2.5_{sys}x10^{-12}x (E/1TeV)^{-Gamma} cm^{-2} s^{-1} TeV^{-1}
with a photon index Gamma of 2.4+-0.3_{stat}+-0.2_{sys}, which is compatible
with that of the H.E.S.S. observations. By combining our result with
multi-wavelength data, we discuss the possible counterparts for HESS J1614-518
and consider radiation mechanisms based on hadronic and leptonic processes for
a supernova remnant, stellar winds from massive stars, and a pulsar wind
nebula. Although a leptonic origin from a pulsar wind nebula driven by an
unknown pulsar remains possible, hadronic-origin emission from an unknown
supernova remnant is preferred.Comment: 9 pages, 7 figures, accepted for publication in Ap
Searches for very high energy gamma rays from blazars with CANGAROO-III telescope in 2005-2009
We have searched for very high energy (VHE) gamma rays from four blazars
using the CANGAROO-III imaging atmospheric Cherenkov telescope. We report the
results of the observations of H 2356-309, PKS 2155-304, PKS 0537-441, and 3C
279, performed from 2005 to 2009, applying a new analysis to suppress the
effects of the position dependence of Cherenkov images in the field of view. No
significant VHE gamma ray emission was detected from any of the four blazars.
The GeV gamma-ray spectra of these objects were obtained by analyzing Fermi/LAT
archival data. Non-simultaneous wide range (radio to VHE gamma-ray bands)
spectral energy distributions (SEDs) including CANGAROO-III upper limits, GeV
gamma-ray spectra, and archival data are discussed using a one-zone synchrotron
self-Compton (SSC) model in combination with a external Compton (EC) radiation.
The HBLs (H 2356-309 and PKS 2155-304) can be explained by a simple SSC model,
and PKS 0537-441 and 3C 279 are well modeled by a combination of SSC and EC
model. We find a consistency with the blazar sequence in terms of strength of
magnetic field and component size.Comment: 11 pages, 8 figures, Accepted for publication in Astroparticle
Physic
Limb-shaking transient ischemic attacks: case report and review of literature
BACKGROUND: Limb shaking Transient Ischemic Attack is a rare manifestation of carotid-occlusive disease. The symptoms usually point towards a seizure like activity and misdiagnosed as focal seizures. On careful history the rhythmic seizure like activity reveals no Jacksonian march mainly precipitated by maneuvers which lead to carotid compression. We here present a case of an elderly gentleman who was initially worked up as suffering from epileptic discharge and then later on found to have carotid occlusion. CASE PRESENTATION: Elderly gentleman presented with symptoms of rhythmic jerky movements of the left arm and both the lower limbs. Clinical suspicion of focal epilepsy was made and EEG, MRI-Brain with MRA were done. EEG and MRI-Brain revealed normal findings but the MRA revealed complete occlusion of right internal carotid artery. On a follow-up visit jerky movements of the left arm were precipitated by hyperextension and a tremor of 3â4 Hz was revealed. Based on this the diagnosis of low flow TIA was made the patient was treated conservatively with adjustment of his anti-hypertensive and anti-platelet medications. CONCLUSION: Diagnosis of limb-shaking TIA is important and should be differentiated from other disorders presenting as tremors. Timely diagnosis is important as these patients are shown to benefit from reperfusion procedures either surgical or radiological reducing their risk of stroke
Readout technologies for directional WIMP Dark Matter detection
The measurement of the direction of WIMP-induced nuclear recoils is a compelling but technologically challenging strategy to provide an unambiguous signature of the detection of Galactic dark matter. Most directional detectors aim to reconstruct the dark-matter-induced nuclear recoil tracks, either in gas or solid targets. The main challenge with directional detection is the need for high spatial resolution over large volumes, which puts strong requirements on the readout technologies. In this paper we review the various detector readout technologies used by directional detectors. In particular, we summarize the challenges, advantages and drawbacks of each approach, and discuss future prospects for these technologies
Voxel-based analysis of 201Tl SPECT for grading and diagnostic accuracy of gliomas: comparison with ROI analysis
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Mitochondrial iron chelation ameliorates cigarette-smoke induced bronchitis and emphysema in mice
Chronic obstructive pulmonary disease (COPD) is linked to both cigarette smoking and genetic determinants. We have previously identified iron-responsive element binding protein 2 (IRP2) as an important COPD susceptibility gene, with IRP2 protein increased in the lungs of individuals with COPD. Here we demonstrate that mice deficient in Irp2 were protected from cigarette smoke (CS)-induced experimental COPD. By integrating RIP-Seq, RNA-Seq, gene expression and functional enrichment clustering analysis, we identified IRP2 as a regulator of mitochondrial function in the lung. IRP2 increased mitochondrial iron loading and cytochrome c oxidase (COX), which led to mitochondrial dysfunction and subsequent experimental COPD. Frataxin-deficient mice with higher mitochondrial iron loading had impaired airway mucociliary clearance (MCC) and higher pulmonary inflammation at baseline, whereas synthesis of cytochrome c oxidase (Sco2)-deficient mice with reduced COX were protected from CS-induced pulmonary inflammation and impairment of MCC. Mice treated with a mitochondrial iron chelator or mice fed a low-iron diet were protected from CS-induced COPD. Mitochondrial iron chelation also alleviated CS-impairment of MCC, CS-induced pulmonary inflammation and CS-associated lung injury in mice with established COPD, suggesting a critical functional role and potential therapeutic intervention for the mitochondrial-iron axis in COPD
Readout technologies for directional WIMP Dark Matter detection
The measurement of the direction of WIMP-induced nuclear recoils is a compelling but technologically challenging
strategy to provide an unambiguous signature of the detection of Galactic dark matter. Most directional detectors aim
to reconstruct the dark-matter-induced nuclear recoil tracks, either in gas or solid targets. The main challenge with directional detection is the need for high spatial resolution over large volumes, which puts strong requirements on the
readout technologies. In this paper we review the various detector readout technologies used by directional detectors.
In particular, we summarize the challenges, advantages and drawbacks of each approach, and discuss future prospects
for these technologies
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