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Elective cancer surgery in COVID-19-free surgical pathways during the SARS-CoV-2 pandemic: An international, multicenter, comparative cohort study

Author: Aawsaj Y.
Abad Gurumeta A.
Abad-Motos A.
Abate E.
Abatini C.
Abbadessa F.
Abbas A. M.
Abbassi-Ghadi N.
Abbott D.
Abbott T.
Abd Elazeem H. A. S.
Abdalla M.
Abdallah M.
Abdel Al S.
Abdel Jalil R.
Abdeldayem H.
Abdelkader Salama I.
Abdelkarem M. M.
Abdelkarim M.
Abdelmajeed A.
Abdelrahman A.
Abdelrahman S.
Abdelsamed A.
Abdou M.
Abdulkareem A.
Abdulwahed E.
Abdur-Rahman L.
Abel M. K.
Abellan M.
Aboelkassem Ibrahim A.
Abosamak N. E.
Abou Chaar M. K.
Abou-Khalil J.
Abouassi A.
Aboulkassem H.
Abreu Da Silva A.
Abu J.
Abu Za'nouneh F. J.
Abu-Nayla I.
Abubakar A.
Acebes Garcia F.
Achalandabaso Boira M.
Acher A.
Acrich E.
Adamina M.
Adamoli L.
Addae-Boateng E.
Aderombi A.
Adeyeye A.
Adiamah A.
Adishesh M.
Agapov M.
Aggarwal A.
Aghayeva A.
Agilinko J.
Agnes A.
Agostini C.
Agoston P.
Agrawal A.
Agresta F.
Aguado H.
Aguilar Gonzalez M.
Aguzzoli L.
Ahad S.
Ahmadi N.
Ahmeidat A.
Ahn J. H.
Aiken T.
Aime A.
Ajlan A.
Akalin M.
Akaydin E.
Akeel N.
Akgor U.
Akhtar M. A.
Akhter Rahman M. M.
Akilli H.
Akin E.
Akkour K.
Akmenkalne L.
Al Abdallah M.
Al Awwad S.
Al Habes H.
Al Maadany F. S.
Al Raddadi R.
Al-Habib A.
Al-Habsi R.
Al-Ishaq Z.
Al-Khayal K.
Al-Masri M.
Al-Mohammad A.
Al-Mukhtar A.
Al-Najjar H.
Al-Omishy H.
Al-Sarireh B.
AL-Sayed M.
Al-Tamimi Y.
Alaa S.
AlAamer O.
Aladeojebi A.
Alam F.
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Alanbuki A.
Alatar A.
Alawneh F.
Alazawi D.
Albertsmeier M.
Albi Martin B.
Alburakan A.
Alcaide Matas F.
Alconchel F.
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Aldecoa Ansorregui I.
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Publication venue: 'American Society of Clinical Oncology (ASCO)'
Publication date: 01/01/2021
Field of study

PURPOSE As cancer surgery restarts after the first COVID-19 wave, health care providers urgently require data to determine where elective surgery is best performed. This study aimed to determine whether COVID-19–free surgical pathways were associated with lower postoperative pulmonary complication rates compared with hospitals with no defined pathway. PATIENTS AND METHODS This international, multicenter cohort study included patients who underwent elective surgery for 10 solid cancer types without preoperative suspicion of SARS-CoV-2. Participating hospitals included patients from local emergence of SARS-CoV-2 until April 19, 2020. At the time of surgery, hospitals were defined as having a COVID-19–free surgical pathway (complete segregation of the operating theater, critical care, and inpatient ward areas) or no defined pathway (incomplete or no segregation, areas shared with patients with COVID-19). The primary outcome was 30-day postoperative pulmonary complications (pneumonia, acute respiratory distress syndrome, unexpected ventilation). RESULTS Of 9,171 patients from 447 hospitals in 55 countries, 2,481 were operated on in COVID-19–free surgical pathways. Patients who underwent surgery within COVID-19–free surgical pathways were younger with fewer comorbidities than those in hospitals with no defined pathway but with similar proportions of major surgery. After adjustment, pulmonary complication rates were lower with COVID-19–free surgical pathways (2.2% v 4.9%; adjusted odds ratio [aOR], 0.62; 95% CI, 0.44 to 0.86). This was consistent in sensitivity analyses for low-risk patients (American Society of Anesthesiologists grade 1/2), propensity score–matched models, and patients with negative SARS-CoV-2 preoperative tests. The postoperative SARS-CoV-2 infection rate was also lower in COVID-19–free surgical pathways (2.1% v 3.6%; aOR, 0.53; 95% CI, 0.36 to 0.76). CONCLUSION Within available resources, dedicated COVID-19–free surgical pathways should be established to provide safe elective cancer surgery during current and before future SARS-CoV-2 outbreaks

Archivio istituzionale della Ricerca - Università degli Studi di Parma

Elective Cancer Surgery in COVID-19-Free Surgical Pathways During the SARS-CoV-2 Pandemic: An International, Multicenter, Comparative Cohort Study.

Author: Aawsaj Y.
Abad Gurumeta A.
Abad-Motos A.
Abate E.
Abatini C.
Abbadessa F.
Abbas A. M.
Abbassi-Ghadi N.
Abbott D.
Abbott T.
Abd Elazeem H. A. S.
Abdalla M.
Abdallah M.
Abdel Al S.
Abdel Jalil R.
Abdeldayem H.
Abdelkader Salama I.
Abdelkarem M. M.
Abdelkarim M.
Abdelmajeed A.
Abdelrahman A.
Abdelrahman S.
Abdelsamed A.
Abdou M.
Abdulkareem A.
Abdulwahed E.
Abdur-Rahman L.
Abel M. K.
Abellan M.
Aboelkassem Ibrahim A.
Abosamak N. E.
Abou Chaar M. K.
Abou-Khalil J.
Abouassi A.
Aboulkassem H.
Abreu Da Silva A.
Abu J.
Abu Za'nouneh F. J.
Abu-Nayla I.
Abubakar A.
Acebes Garcia F.
Achalandabaso Boira M.
Acher A.
Acrich E.
Adamina M.
Adamoli L.
Addae-Boateng E.
Aderombi A.
Adeyeye A.
Adiamah A.
Adishesh M.
Agapov M.
Aggarwal A.
Aghayeva A.
Agilinko J.
Agnes A.
Agostini C.
Agoston P.
Agrawal A.
Agresta F.
Aguado H.
Aguilar Gonzalez M.
Aguzzoli L.
Ahad S.
Ahmadi N.
Ahmeidat A.
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Ajlan A.
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Akeel N.
Akgor U.
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Akhter Rahman M. M.
Akilli H.
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Yurttas C.
Zacharoulis D.
Zafar S. N.
Zakai D.
Zakaria A. D.
Zakaria R.
Zakaria Z.
Zambelli M. F.
Zambon M.
Zamora L.
Zamvar V.
Zani S.
Zanotti S.
Zanus G.
Zapardiel I.
Zarabini A. G.
Zatecky J.
Zegarac M.
Zelic M.
Zeller N.
Zengin A. K.
Zerbib P.
Zervas K.
Zese M.
Zhang H.
Zivanovic M.
Zivkovic M.
Zizzo M.
Zografos C.
Zonta S.
Zorrilla Ortuzar J.
Zourntou S.
Zouzoulas D.
Zubaidi A.
Zullo A.
Publication venue: J Clin Oncol
Publication date: 01/01/2020
Field of study

PURPOSE: As cancer surgery restarts after the first COVID-19 wave, health care providers urgently require data to determine where elective surgery is best performed. This study aimed to determine whether COVID-19-free surgical pathways were associated with lower postoperative pulmonary complication rates compared with hospitals with no defined pathway. PATIENTS AND METHODS: This international, multicenter cohort study included patients who underwent elective surgery for 10 solid cancer types without preoperative suspicion of SARS-CoV-2. Participating hospitals included patients from local emergence of SARS-CoV-2 until April 19, 2020. At the time of surgery, hospitals were defined as having a COVID-19-free surgical pathway (complete segregation of the operating theater, critical care, and inpatient ward areas) or no defined pathway (incomplete or no segregation, areas shared with patients with COVID-19). The primary outcome was 30-day postoperative pulmonary complications (pneumonia, acute respiratory distress syndrome, unexpected ventilation). RESULTS: Of 9,171 patients from 447 hospitals in 55 countries, 2,481 were operated on in COVID-19-free surgical pathways. Patients who underwent surgery within COVID-19-free surgical pathways were younger with fewer comorbidities than those in hospitals with no defined pathway but with similar proportions of major surgery. After adjustment, pulmonary complication rates were lower with COVID-19-free surgical pathways (2.2% v 4.9%; adjusted odds ratio [aOR], 0.62; 95% CI, 0.44 to 0.86). This was consistent in sensitivity analyses for low-risk patients (American Society of Anesthesiologists grade 1/2), propensity score-matched models, and patients with negative SARS-CoV-2 preoperative tests. The postoperative SARS-CoV-2 infection rate was also lower in COVID-19-free surgical pathways (2.1% v 3.6%; aOR, 0.53; 95% CI, 0.36 to 0.76). CONCLUSION: Within available resources, dedicated COVID-19-free surgical pathways should be established to provide safe elective cancer surgery during current and before future SARS-CoV-2 outbreaks

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Outcomes from elective colorectal cancer surgery during the SARS-CoV-2 pandemic

Author: 14 | COVIDSurg COllabOratIVe Tzovaras G. (General University Hospital of Larissa)
Aawsaj Y.
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COVIDSurg COllabOratIVe | 15 Violante T. (IRCCS Azienda Ospedaliero – Universitaria di Bologna
Cozza V.
Creavin B.
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Kulkarni R.
Kulle C. B. (Koç University Medical School)
Kutkevičius J.
Kyriacou H.
Köken H.
Königsrainer A.
Küçük I. F.
La Regina D.
La Torre F.
Labib P.
Lacy A. M.
Ladd M. R.
Laface L.
Laforest A.
Laharwal A.
Lakkis Z. Manfredelli S. (CHU Besançon)
Lala A. K.
Lalou L.
Lapolla P.
Larentzakis A.
Larkin J. O.
Latinčić S.
Lauretta A.
Lauscher J. C.
Lawday S. Lyons A. (Southmead Hospital)
Le Roy B.
Lecolle K.
Ledesma F. S.
Lee M.
Leece)
Leede E.
Lenzi E.
Leon R.
Lewis-Lloyd C.
Li Z.
Liakakos T.
Liao C. C. L.
Lim M.
Lima da Silva C.
Lima M. J.
Linari C.
Litta F.
Litvina Y.
Lizzi V.
Loch F. N.
Lomonosov Moscow State University). Saudi Arabia: Alshahrani M.
Long C.
Longhi M.
Lopes L.
Lopez F.
Lora- Cumplido P. Sosa M. V. (Hospital de Cabueñes)
Lorenzon L.
Losada M. (Hospital Universitario del Sureste)
Lott N.
Loubani M.
Loutzidou L. (George Papanikolaou General Hospital of Thessaloniki)
Lowery A.
Lozano Lominchar P.
Lucchini S. M. (Sanatorio Allende). Australia: Cecire J.
Luglio G.
Lunghi E. G.
Lynch N.
Lázaro A.
Löffler M. W.
Löfgren N.
M. elghazaly S.
MacCabe T.
MacDonald L.
Machado D.
Machado N.
Madonini M.
Maffioli A. (Ospedale Luigi Sacco Milano)
Magee C. Powell S. (Wirral University Teaching Hospital)
Magowan D.
Mahendran V. (Worcestershire Royal Hospital)
Mahmood M.
Mahmoud Ali F. (Newcastle Upon Tyne Hospitals NHS Foundation Trust. )
Maida P.
Majbar A. M.
Majkowska A.
Mak T. W. C.
Malapati H.
Malcolm F. L.
Malgras B. (Hia Begin)
Malibary N.
Mall J. (KRH Nordstadt-Siloah Hospitals)
Maltinti G.
Manatakis D. K.
Mancini S.
Manku B.
Manso M. I.
Manson J.
Mantoglu B. (Sakarya University Faculty of Medicine)
Manu N.
Maqueda González R.
Marano A.
Marcos-Santos P.
Margalit A.
Mari G.
Marialva J.
Mariani N. M.
Marie-Macron L. (Centre Hospitalier Avignon)
Marino Cosentino L.
Marino M. V.
Markaryan D.
Markovic I.
Markovic V.
Maroli A.
Marques R.
Marqueta De Salas M.
Marra A. A.
Marra E.
Marte G.
Martin E.
Martin-Perez E. (Hospital Universitario de la Princesa)
Martinez German A.
Martins D.
Martins dos Santos G.
Martins Jordão D.
Martins R.
Martín L.
Martín-Arévalo J.
Martínez Chicote C.
Martínez-Hurtado E.
Martínez-Pinedo C.
Martínez-Pérez P.
Marx W. (SUNY Upstate University Hospital)
Marzi F.
Marçal A.
Marín H.
Massey L.
Massie E.
Massobrio A.
Mastoridis S.
Math S.
Matić S.
Matos Costa P. (Hospital Garcia de Orta)
Matute M.
Maté P.
Maw A.
McAleer J.
McAree B.
McCanny A.
McCluney S.
McCormick P.
McDermott F.
McElhinney K.
McEwen R. (University College London Hospital)
McGivern K.
McIntyre J.
McKevitt K.
McLarty N.
McNicol F.
Mehigan B. J.
Mehraj A.
Meima-van Praag E. M.
Memon A. S.
Memos N.
Mendes F. (Centro Hospitalar Cova da Beira)
Mendes J. R.
Mendoza-Moreno F.
Meneghini S.
Menoufia University). Finland: Kauppila J. H.
Mercado M. Á.
Metwalli M.
Michalopoulos N.
Michalski C.
Michel M.
Migliore M.
Mignot G.
Miguel T.
Mihanovic J.
Mihmanli M.
Miladinov M.
Milan)
Milano)
Milanović M.
Mills S.
Milne K.
Mingoli A.
Minicozzi A.
Ministry of National Guard
Minto G.
Mir I.
Mirabella A.
Miranda P.
Mitchell D.
Mithany R.
Mitrofan C. G.
Miu V.
Mochet S. Usai A. (Ospedale Regionale Umberto Parini)
Mohamed Sidek A. S.
Mohammad Z.
Mohammed M. M.
Mohan H.
Mohd Yunus M. F.
Mohsine R.
Mondovì)
Mongelli F. (Ente Ospedaliero Cantonale)
Montelatici M.
Monteleone M. (San Leopoldo Mandic)
Montella M. T.
Montori G.
Mora-Guzmán I. (Hospital Santa Bárbara)
Morais H.
Moras L.
Morelli L.
Morgan R.
Moritani K. (National Cancer Center Hospital). Jordan: Al Abdallah M.
Moro-Valdezate D.
Morris A.
Morsi A.
Mosley F. (Bradford Royal Infirmary)
Moss J.
Moura F.
Mourad M.
Muguerza J. M.
Muiesan P.
Mukherjee S.
Mulligan C.
Muratore A.
Murphy C.
Mustafa A. (Gateshead Health NHS Foundation Trust)
Mutter D.
Muzamil J.
Muñoz Camarena J. M.
Muñoz-Atienza V.
Nafees Ahmed R.
Nageh M. A.
Nahm C. (Leeds Teaching Hospitals Trust)
Nally D.
Nassa H.
Nassif M.
Natale J.
Navaratne L.
Nazir S.
Neary P. C.
Neary P. M.
Neely D. (Antrim Area Hospital – Northern Health and Social Care Trust)
Nel D.
Nelli T.
Neri J.
Nespoli L. C. Tamini N. (Ospedale San Gerardo)
Nessim C.
Newman T.
Newton C. (University Hospitals Bristol NHS Foundation Trust)
Newton K.
Ng H. J. (Dumfries and Galloway Royal Infirmary)
Ng S. S. M. (Prince of Wales Hospital)
Ng V.
Ng V. (Medway Hospital)
Nikaj H. (Azienda Ospedaliero Universitaria Maggiore della Carità)
Nikolic S.
Nitschke C.
Nogueira O.
Nogueiro J.
Nogués A.
Nolan G. J.
Norcini C. (San Giovanni di Dio)
Nordberg M.
Nouh T.
Novello S.
Nowak K. Reinhard T. (Romed Klinikum Rosenheim)
Ntziovara A. M.
Nunes Coelho M.
Nunez-Garcia B.
Nuñez del Barrio H.
Obeidat K. (King Abdullah University Hospital)
Oguttu B. (Kampala International University Teaching Hospital). UK: Agilinko J.
Olasehinde O.
Oliva Mompean F.
Oliveira A.
Olivier J. (Weston General Hospital)
Olivieri M.
Olson K. A.
Onos L.
Oosterlinck W.
Oosterling S. (Spaarne Gasthuis)
Opocher E.
Ortega Vázquez I.
Ortiz de Solórzano Aurusa F. J.
Osman N. (Alexandria Medical Research Institute)
Osorio A.
Otero A.
Ovejero Merino E.
Owen H.
Owens P.
Oyende O.
Ozben V.
Ozgediz D.
Ozmen B. B. (Acibadem Atakent Hospital)
O’Brien H.
O’Brien S.
O’Malley S.
O’Riordan J. M.
O’Shea M.
Pacheco Sánchez D.
Padilla-Valverde D.
Padmore G.
Pagano G.
Palagi S.
Palmeri M.
Panahi P.
Papaconstantinou I.
Papatheodorou P.
Paquette N.
Parasyris S.
Parello A.
Parente A.
Parini S.
Parise P.
Parkin E. (Royal Preston Hospital)
Parkins K.
Parlanti D.
Parmar C.
Parra Baños P. A.
Parray F.
Parreira R. (Hospital do Divino Espírito Santo)
Parseliunas A.
Parwaiz I.
Pascale IRCCS)
Pascale IRCCS)
Paspaliari D.
Passot G. (Hopital Lyon Sud)
Patel K.
Patel M.
Patel P.
Patil S.
Patrone R. (HPB Surgical Oncology Unit – Istituto Nazionale Tumori Fondazione
Patrício B.
Pattyn P. (Az Delta)
Pavlov M.
Pedrazzani C.
Peirce C. (University Hospital Limerick)
Pejnovic L.
Pejovic I.
Pellegrino L.
Pellino G. (Vall d’Hebron University Hospital). Sri Lanka: Arulanantham A.
Peluso C.
Peralta Ferreira M.
Pereca J. (University Hospital Ayr)
Pereira A.
Pereira C.
Pereira R.
Pereira Rodrigues A.
Perez D.
Perez Gonzalez M.
Pergolini I. Reim D. (Klinikum Rechts der Isar TUM School of Medicine)
Perivoliotis K.
Peros G. (Kantonsspital Winterthur). Turkey: Aghayeva A.
Perotto L. O.
Perra T.
Persiani R.
Pertile D.
Petrillo A.
Petropoulos K.
Peyroteo M.
Pezzuto A. P.
Peña Ros E.
Phan D. Townend D. (Lismore Base Hospital)
Phillips E.
Picardo A. L.
Pickett L. (Connolly Hospital Blanchardstown)
Picón Rodríguez R.
Pieniowski E. (Stockholm South General Hospital)
Piessen G.
Pieve Emanuele (Mi))
Pina S.
Pinto J. Tojal A. (Centro Hospitalar Tondela-Viseu)
Pipitone Federico N. S. (Edoardo Agnelli)
Pisani Ceretti A. (ASST Santi Paolo E. Carlo)
Pisanu A.
Pizarro M. J.
Pizzini P. (Ospedale Maggiore di Lodi)
Pla Marti V. (Hospital Clínico Universitario de Valencia)
Poch C.
Pockney P. (John Hunter Hospital)
Podda M. (Cagliari University Hospital)
Poggioli G.
Polydorou A.
Popoola A. (University of Ilorin Teaching Hospital). Pakistan: Jamal A.
Porcu A.
Portinari M.
Posadas-Trujillo O. E.
Posma-Bouman L. (Slingeland Ziekenhuis)
Potter R. (Royal Bournemouth Hospital)
Pourcher G.
Pozotou I.
Praetorius C.
Prando D.
Presl J.
Price C.
Prieto Calvo M.
Prieto Nieto M. I.
Pronk A. J. M.
Prosperi P.
Provozina A. (Immanuel Kant Baltic Federal University
Pruvot F. R.
Pérez Sánchez M. A.
Pérez-Saborido B.
Qasem A. (Al- Basheer Hospital)
Qatora M. S.
Quante M.
Qureshi A.
Raby-Smith W.
Rai . L (Dr Ruth K. M. Pfau Civil Hospital)
Rajaretnam N. (Royal Devon and Exeter Hospital)
Rakvin I. (Zadar General Hospital). Cyprus: Frantzeskou K.
Ramachandran A. (Tunbridge Wells Hospital)
Ramamoorthy 18 | COVIDSurg COllabOratIVe R.
Ramcharan S.
Ramesh P.
Ramirez Faraco M.
Ramos Bonilla A.
Ramos-Martín P.
Ramwell A.
Rapaport S.
Rashid A. (SMHS Hospital
Rashid M. M.
Rattizzato S.
Ratto C.
Ravindrakumar S.
Ravindran S.
Rayamajhi S. (Groote Schuur Hospital). Spain: Paniagua García Señorans M.
Raymond T.
Razafindrahita J. B.
Redfern J.
Rega D.
Regional Clinical Hospital)
Reilly J.
Revez T.
Rey Valcarcel C.
Reynolds I. S.
Ribeiro A.
Ribeiro C. G.
Ribeiro R.
Ribeiro V. I.
Ribolla M. (Ospedale Guglielmo da Saliceto Piacenza)
Rice D.
Richards T.
Ridgway P. F.
Righini E. (Azienda Unità Sanitaria Locale di Ferrara
Riley C.
Rimonda R.
Ringressi M. N.
Ripollés-Melchor J.
Risaliti M.
Rizzi A. (ASST Sette Laghi-Varese)
Robinson A.
Rodimov S.
Rodrigo V. S. D. (District General Hospital Chilaw)
Rodriguez J. L.
Rodríguez Gómez L. (Severo Ochoa University Hospital)
Rogers L. (Derriford Hospital)
Rojo López J. A.
Romano M.
Romero de Diego A.
Ronellenfitsch U. (University Hospital Halle (Saale))
Rooney S.
Rosa F.
Rose J.
Roslani A. C. (University Malaya Medical Centre). Mexico: Buerba G. A.
Rossi S.
Rottoli M.
Roy Mahapatra S.
Royle T.
Rozzano (Mi) and Humanitas University
Rubio-Perez I.
Ruivo A.
Ruiz Escobar A. (Infanta Leonor University Hospital)
Ruiz Soriano M.
Ruiz-Marín M.
Russ J.
Rutegård M. (Umea University Hospital). Switzerland: Arigoni M.
Rutherford D.
Ruzzenente A.
Ryan M. (University Hospital Waterford/University College Cork). Italy: Macina S. (ASST Mantua)
Ryan É. (University Hospital Galway)
Ryska O. (Royal Lancaster Infirmary)
Río Lafuente F. D.
Saad M. M.
Saafan T.
Saavedra J.
Sabah)
Sabratha)
Sabry A.
Saeed S.
Saez Carlin P.
Sagar J.
Sagnotta A. (Ospedale San Filippo Neri)
Sahin I. (Acibadem Altunizade Hospital)
Sahnan K. (Northwick Park Hospital)
Salazar A.
Saleem A.
Salem H.
Salgado-Nesme N.
Salimoğlu S.
Salindera S.
Sallam I.
Samih A.
Samir Abdelaal A.
Samison L. H. (Joseph Ravoahangy Andrianavalona Hospital). Malaysia: Hamdan K. H.
Samkari A.
Sammarco G.
Sammour T. (Royal Adelaide Hospital)
Sampaio da Nóvoa Gomes Miguel I. I. (Centro Hospitalar Universitário do Algarve – Unidade de Portimão)
Sampietro G. M. (Ospedale di Rho – ASST Rhodense)
San Francisco (UCSF))
Sanchez Cabezudo Noguera F.
Sanchez Gonzalez J.
Sanchez Jimenez R.
Sanchez-Pelaez D. (Hospital General Universitario de Ciudad Real)
Sancho-Muriel J. (Hospital Universitario Y Politécnico la Fe)
Sanchon L.
Sanli A. N.
Santanach C.
Santarrufina Martinez S.
Santero-Ramirez M. S.
Santos P. M. D. D.
Santos R.
Santos-Sousa H.
Sanz Larrainzar A.
Sanz Ortega G.
Sanz-Lopez R.
Sapienza P.
Sapre D.
Saraiva P.
Sarantitis I.
Sarigul M.
Sarin A.
Sarjanoja E. (Länsi-Pohja Central Hospital)
Sarma D. R.
Sarre C. (Instituto Nacional de Ciencias Médicas y Nutrición ‘Salvador Zubirán’). Morocco: Amrani L.
Sartarelli L.
Sarveswaran J.
Sasapu K. (Diana Princess of Wales Hospital Grimsby)
Sasia D.
Saudí S. (Hospital Universitario Miguel Servet)
Sauvain M. (Pourtales Neuchatel Hospital)
Sauvat F. (CHU Réunion). Romania: Bezede C.
Savković N.
Sayyed R. (Patel Hospital)
Scabini S.
Scalabre A. (Chu Saint Etienne)
Scanu A. M. (Cliniche San Pietro
Schiavo M. (Ospedale Vittorio Emanuele III – Carate Brianza)
Schiergens T.
Schineis C. (Charité University Medicine
Schizas D.
Schlesinger N.
Schwartz P.
Scott L. (Pinderfields Hospital)
Scotton G. (St Moritz Hospital)
Scrima O.
Sechenov Medical State University)
Seebah K.
Seeliger B. (Strasbourg University Hospitals/IHU-Strasbourg)
Seguin-Givelet A.
Sehgal T.
Selmani J.
Semina E. (Moscow Research and Educational Center
Senossi O.
Serevina O. L.
Serralta de Colsa D. (Infanta Sofía University Hospital)
Serrano González J. (Hospital Universitario de Torrejón de Ardoz)
Serrano-Navidad M.
Sert İ.
Seymour Z. (Ysbyty Gwynedd). USA: Haynes A.
Sganga G. (Fondazione Policlinico Universitario Agostino Gemelli IRCCS)
Sgrò A.
Shah J. (North Manchester General Hospital)
Shah S. (The Whittington Hospital)
Shah Z. A.
Shaikh I.
Shaikh S.
Sharabiany S. (Amsterdam UMC
Sharma P. (Aberdeen Royal Infirmary)
Shehata S.
Shenfine A. (Northumbria NHS Hospital Trust)
Shenit K. (Alexandria Main University Hospital)
Sheridan K.
Sherief M.
Sherif A. (Misr Cancer Center)
Sherif A. E. (National Liver Institute
Sherif G. (National Cancer Institute)
Shokuhi P.
Shortland T.
Sian T.
Sibilla M. G.
Sidiropoulos T.
Silva M.
Silva N.
Silva R.
Silveira Nunes I.
Simões J. (Centro Hospitalar e Universitário de Coimbra)
Singh A.
Singh S. (Queen’s Hospital Romford)
Skrovina M.
Smith C.
Smith H. (Bispebjerg Hospital). Egypt: Al Sayed M.
Smith L.
Smith. J (St James’s Hospital)
Soares A. P.
Soh J. Y.
Sohrabi C.
Solari F.
Soriero D. (IRCCS Ospedale Policlinico San Martino)
Sorrentino L. (Fondazione IRCCS Istituto Nazionale dei Tumori
Sorribas Grifell M.
Soto Montesinos C. (Fundació Althaia – Xarxa Assistencial Universitària de Manresa)
Souadka A. (Institut National d’Oncologie
Soulikia K.
Sousa Fernandes M. (Hospital Beatriz Angelo)
Sousa R. (Centro Hospitalar Universitário Lisboa Central)
Sousa S.
Spagni G.
Spampinato M. G. (Vito Fazzi
Spartalis E.
Spencer N.
Spiezio G. (Colorectal Surgical Oncology Unit – Istituto Nazionale Tumori Fondazione
Spinelli A. (Humanitas Clinical and Research Center IRCCS
Sreedharan L.
Sriram R. K.
Srishankar S. (Teaching Hospital Anuradhapura). Sudan Ali Adil A. K. (Al-Rajhi). COVIDSurg COllabOratIVe | 17 Sweden: Älgå A.
St John S.
Stafford J. (George Eliot Hospital)
Stavrinidou O.
Steele C. (Sheffield Teaching Hospital NHS Foundation Trust)
Steidle C.
Steinke J.
Stevens K.
Stevenson J. (The Ottawa Hospital). Croatia: Bačić G.
Stevic D.
Stewart K. E.
Stylianides N. (Manchester Royal Infirmary)
Stylianidis G. (Evaggelismos General Hospital)
Subhi M. T. (Alkhadra Hospital)
Subocius A.
Subramaniam S. (Queen Elizabeth Hospital and Universiti Malaysia Sabah
Sundaram Venkatesan G. (Glan Clwyd Hospital)
Suszták N. (Szent Borbála Kórház). India: Bhat G. A.
Sutherland A. (Coffs Harbour Health Campus)
Swinson B. (Royal Brisbane and Women’s Hospital). Austria: Messner F.
Syed W. A. S.
Syllaios A.
Szatmary P.
Szubota I. (Hospital and Oncological Centre Novy Jicin). Denmark: Ebbehøj A. L.
Sánchez del Pueblo C.
Sánchez Fuentes N.
Sánchez- Pernaute A.
Sánchez- Rubio M.
Sánchez-García S.
Taddei A.
Tadic B.
Taibi A. (Chu Limoges)
Talal El-Abur I.
Talwar R. (Luton and Dunstable University Hospital)
Tammaro P.
Tan J. A.
Tan X. S.
Tanal M.
Tang A. M.
Tanzanu M.
Tartaglia D. (Azienda Ospedaliero Universitaria Pisana)
Tasis N. (Athens Naval and Veterans Hospital)
Tatar O. C.
Tavares F.
Tayeh S. (Homerton University Hospital)
Tebala G. D.
Teixeira J. (Centro Hospitalar Universitário do Algarve – Unidade de Faro)
Teixeira M. (Centro Hospitalar do Tamega e Sousa)
Tejero- Pintor F. J. (Hospital Universitario Río Hortega)
Testa V. (Santa Croce E. Carle Hospital
Tewari N. (University Hospitals Coventry and Warwickshire NHS Trusts)
Tezas S. (Furness General Hospital)
Thaha M.
Thanapal M. R. (Hospital Kuala Lumpur)
Theodosopoulos T.
Theophilidou E. (Royal Derby Hospital)
Thian A.
Thomas A. (Royal Liverpool University Hospital)
Thompson D. (Morriston Hospital Swansea)
Thornhill M. (Dell Seton Medical Center at the University of Texas)
Thrumurthy S. (Epsom and St Helier University Hospitals NHS Trust)
Thulasiraman S. V.
Timbrell S.
Tirloni L.
Titu S. (Prof. Dr. Ion Chiricuta Institute of Oncology). Russia: Garmanova T.
Tonini V. (S. Orsola-Malpighi Hospital)
Torres A. (Hospital Clínico de Madrid)
Torres Arcos C.
Townson A.
Trabulsi N. (King Abdulaziz University Hospital)
Travaglio E. (Regina Montis Regalis Hospital
Tribillon E. (Institut Mutualiste Montsouris)
Troncoso Pereira P. (Hospital Mateu Orfila)
Tropeano F. P. (Federico II University Hospital)
Trujillo Díaz J.
Tsai L.
Tsarkov P.
Tsiamalou I.
Tsiaoussis I.
TU Dresden)
Tucci R. (Azienda Ospedaliera Universitaria Careggi)
Tufo A. (Ospedale del Mare)
Tugmen C.
Tulina I. (Clinic of Coloproctology and Minimally Invasive Surgery
Tuncer K.
Turnbull A. (Victoria Hospital Kirkcaldy)
Turrado-Rodriguez V.
Turri G. (Azienda Ospedaliera Universitaria Integrata di Verona)
Tweedle E. (Addenbrooke’s Hospital)
Ugarte-Sierra B. (Hospital Universitario de Galdakao)
Uludağ S. S.
Umair M.
Universiti Sains Malaysia)
University of Amsterdam)
Università di Ferrara)
Université Mohammed V Rabat). Netherlands: Hompes R.
Uras C. (Acibadem Maslak Hospital)
Urbani A. (Azienda Ospedaliero Universitaria San’anna)
Urbieta A. (Hospital Universitario la Paz)
Uslu G.
Utkan N. Z.
Uyanik M. S. (Samsun Training and Research Hospital)
Uzunoglu F. G. (University Medical Center Hamburg–Eppendorf). Greece: Antonakis P.
Vaccarella G. (Azienda Ospedaliera Ospedali Riuniti Villa Sofia-Cervello)
Valbuena Jabares V. (Marqués de Valdecilla University Hospital)
Valdes- Hernandez J. (Hospital Universitario Virgen Macarena)
Valero Soriano M. (Hospital General Reina Sofía)
Valle Rubio A. (Getafe University Hospital)
Valverde S. (Hospital Clinic Barcelona)
Van den Eynde J.
Van den Eynde R. (Uz Leuven). Bulgaria: Sokolov M. (University Hospital Alexandrovska). Canada: Boutros M.
Varma M. (University of California
Vasljević J.
Vassiliu P. (Attikon University General Hospital)
Vaz Pereira R.
Vaz S. (Centro Hospitalar e Universitário de São João)
Velchuru V.
Velickovic D. (Clinic for Digestive Surgery
Velidedeoglu M.
Venn M. (Royal London Hospital)
Venskutonis D. (Lithuanian University of Health Sciences Kaunas Clinical Hospital). Madagascar: Rasoaherinomenjanahary F.
Vera Mansilla C. (Hospital Universitario Principe de Asturias)
Verberne C. (John Radcliffe Hospital)
Vergari R. (Ospedali Riuniti di Ancona)
Vernon L. (Cork University Hospital)
Vervoort D.
Vescio G. (University ‘Magna Graecia’ of Catanzaro)
Vezakis A. (Aretaieion Hospital)
Videira J. F. (IPO Porto). Réunion: Kassir R.
Vieira B. (Centro Hospitalar de Trás-Os-Montes e Alto Douro
Vieira Caroço T. (IPO Coimbra)
Vieira Paiva Lopes A. C. (Hospital de Torres Vedras – Centro Hospitalar do Oeste)
Vignali A. (San Raffaele Scientific Institute
Vigorita V. (Álvaro Cunqueiro Hospital)
Vijayan D. (Queen Elizabeth Hospital Birmingham)
Villalabeitia Ateca I. (Hospital Universitario Cruces)
Vimalachandran D. (Countess of Chester Hospital)
Viswanath Y. K. S. (James Cook University Hospital)
Vitali A. (Ospedale San Giovanni di Dio)
Vitone L. (Royal Blackburn Hospital)
Vives R. V. (Bellvitge University Hospital)
Vo U. G. (Fiona Stanley Hospital)
Von Papen M.
Vovola F. (Ospedali Riuniti Azienda Ospedaliera Universitaria Foggia)
Vucic N.
Vázquez Fernández A. (Hospital Clínico Universitario de Valladolid)
Wadham B. (The University Hospital of South Manchester)
Walkes K. (Queen Elizabeth Hospital). Belgium: Flamey N.
Wani R. (Sher-I-Kashmir Institute of Medical Sciences)
Waqar S. H. (Pakistan Institute of Medical Sciences). Poland: Major P. (Jagiellonian University Medical College). Portugal: Azevedo C.
Warren O. (Chelsea and Westminster Hospital)
Watson L. J. (Sunderland Royal Hospital)
Watson N. (King’s Mill Hospital)
Weitz J.
Welsch T. (Carl-Gustav-Carus University Hospital
Werner J. (LMU Klinikum Campus Innenstadt)
Westwood E. (James Paget University NHS Foundation Trust Hospital)
Whelan M. (Tallaght University Hospital)
Whitmore H. (Torbay and South Devon NHS Trust)
Wilkin R. J. W. (South Warwickshire NHS Foundation Trust)
Wilkins A. (Hull University Teaching Hospitals NHS Trust)
Williams G. (Royal Gwent Hospital)
Williams K. (St George’s Hospital)
Wilson M. (Forth Valley Royal Hospital)
Wimmer A. (Paracelsus Medical University Salzburg). Barbados: Barker D.
Wong M.
Worku D. (Queens Medical Centre)
Wullschleger M. (Gold Coast University Hospital)
Xavier R. G.
Xenaki S.
Xynos E. (University Hospital of Heraklion Crete and Interclinic Hospital of Crete). Hong Kong: Futaba K.
Yang W.
Yassin N. (Royal Wolverhampton NHS Trust)
Ye G.
Yesantharao P.
Yetkin S. G. (Sisli Hamidiye Etfal Training and Research Hospital)
Yeşilyurt D. (University of Health Sciences Tepecik Training and Research Hospital)
Yiallourou A. (Nicosia General Hospital). Czechia: Martinek L.
Yıldırım A.
Yildiz A. (Yildirim Beyazit University Yenimahalle Training and Research Hospital). Uganda: Lule H.
Young R. (York Teaching Hospitals NHS Trust)
Yousof E. A. (Assiut University Hospital)
Youssef M. (Norfolk and Norwich University Hospital)
Yurttas C. (University Hospital Tuebingen)
Yánez C. (Royo Villanova)
Yüksel E. (Kocaeli University Teaching Hospital)
Zafar S. N. (University of Wisconsin)
Zakaria A. D.
Zakaria Z. (School of Medical Sciences and Hospital
Zambon M. (Policlinico Umberto I Sapienza University of Rome)
Zanus G. (Ca’ Foncello Treviso – DISCOG – Università di Padova)
Zegarac M. (Institute for Oncology and Radiology of Serbia)
Zelić M. (University Hospital Center Rijeka)
Zengin A. K. (Istanbul Universty – Cerrahpaşa Medical Faculty)
Zerbib P. (CHU Lille)
Zervas K.
Zese M. (Santa Maria degli Angeli Hospital ULSS 5 – Adria)
Zhang H. (Concord Repatriation General Hospital)
Zizzo M. (Azienda Unità Sanitaria Locale – IRCCS di Reggio Emilia)
Zografos C. (Laiko University Hospital)
Zorrilla Ortúzar J. (Hospital General Universitario Gregorio Marañón)
Zourntou S. (General Hospital of Larissa ‘Koutlimpaneio and Triantafylleio’)
Zubaidi A. M. (King Saud University). Serbia: Aleksić L.
Ângelo M.
Çelebi F.
Çolak E.
Öfner D. (Medical University of Innsbruck)
Öhlberger L.
Özçelık M. F.
Öğücü H.
Überrück L.
Ćoza I.
Publication venue: 'Wiley'
Publication date: 01/01/2020
Field of study

This study aimed to describe the change in surgical practice and the impact of SARS-CoV-2 on mortality after surgical resection of colorectal cancer during the initial phases of the SARS-CoV-2 pandemic

Archivio della ricerca- Università di Roma La Sapienza

Global patient outcomes after elective surgery: prospective cohort study in 27 low-, middle- and high-income countries.

Author: Ab Majid MA
Ab Rahman AS
Ab Rahman R
Abayasinghe C
Abbott T
Abdullah NH
Abdur-Rahman L
Abeloos J
Abernethy C
Abidin UN
Abrunhosa A
Absar M
Adam S
Adams D
Adams G
Adamson M
Adekola O
Adelaja Y
Ademola A
Adenekan A
Adenike O
Adeolu AA
Adetoye A
Adewale B
Adigun T
Adolfsson A
Aflori L
Africander C
Afshari A
Agarwal V
Agodirin O
Aguero Vera M
Aguzzoli C
Ahmad A
Ahmad N
Ahmad T
Ahmad T
Ahmad Y
Ahmed A
Ahmed J
Ai Y
Aignatoaie M
Aimoniotou-Georgiou E
Akanmu O
Akerman N
Akinwale M
Akring I
Al 'Amri K
Al Anizi M
Al hussaini S
Al-Soudaine Y
Aladin H
Alagbe-Briggs O
Alaman Laguarda G
Albaj S
Alcock D
Alcock L
Aldecoa C
Aldecoa C
Aleixo FB
Alexander H
Alexander M
Alexander-Sefre F
Alherz F
Ali H
Ali M
Ali S
Alias A
Alias AH
Alias RLR
Alit MA
Allen S
Allen SJ
Allison J
Alloj C
Allorto NL
Allsop J
Almeida W
Alonso E
Alphonsus C
Alvares D
Alves MJ
Amador JCB
Ameer Y
Amendola CP
Ami N
Amstrup-Hansen L
Anagnou A
Andersen C
Anderson C
Anderson C
Anderson F
Anderson P
Andreadaki E
Andreou A
Andreou P
Andrew A
Andrews E
Angermair S
Angus K
Anillo V
Antal O
Antill P
Antoniadou E
Antonina W
Apagaki E
Apostolou K
Applewhaite C
Aquino LPG
Ar P
Arawwawala D
Ardern D
Argue R
Arkalaki E
Armaganidis A
Armstrong J
Armstrong R
Arnaoutoglou C
Arnaoutoglou E
Arnold G
Arrandale L
Arrich J
Arrigo M
Arshad H
Arshad MA
Arumugam S
Arustei M
Arvaniti K
Arya A
Arya S
Asimakos A
Asudo F
Athanasakis E
Atiku M
Attrill E
Attwood C
Auer P
Avidan M
Avila Sanchez FJ
Avila EJD
Avis J
Awad H
Axioti E
Ayyaz H
Azam UAA
Azambuja P
Azevedo C
Aziz FZ
Baas P
Baghirzada L
Bai H-P
Bai Y
Baillie S
Baines D
Baio TH
Bairaktari A
Baker G
Baker K-A
Baker P
Balain B
Balaji P
Balajonda N
Balanescu A
Balasubramaniam M
Baldisserotto S
Baldwin J
Baldwin M
Balfoussia D
Bali C
Bandeira ME
Banerjee R
Bankewitz C
Banner-Goodspeed V
Bao Q
Barcraft-Barnes H
Barneto L
Barnett A
Baroselli A
Barraclough J
Barras J-P
Barrett S
Barrett WJ
Basanth S
Batchelor N
Bateman B
Bates A
Bates S
Batista HD
Bauchmuller K
Bauer M
Baumgarten G
Baxter L
Beaton C
Beattie S
Beavis V
Bechan S
Bejia T
Belciu I
Belda MT
Bell G
Bell R
Bell S
Bellandi M
Bello J
Beloeil H
Belskiy V
Ben-Menachem E
Benavent P
Benevento A
Bengeri S
Bennett C
Bennett M
Bennett R
Bennett V
Bentley C
Beretta L
Berg A
Bergin C
Bernard A
Berntsen E
Bertram W
Bester D
Bester M
Bettega F
Bettinelli A
Bhardwaj N
Bhatia K
Bhula C
Bi Y
Biais M
Biccard BM
Bidd H
Bidgoli J
Biffen A
Bignami E
Bilolikar A
Bin Mustapha MT
Birch J
Bishop DG
Biyase T
Bizios C
Blackwell C
Blackwood D
Blaj M
Blakemore SP
Bland M
Blunt M
Blyth K
Bocchino S
Bodansky D
Bodger P
Boer C
Boereboom C
Boggiano V
Bogner G
Bolaji B
Bolton D
Boone M
Boschi L
Boshier P
Botes M
Botis I
Bottini C
Bottrill F
Bouchez S
Boulton K
Bouris V
Bourner L
Boutsikos G
Bouwman A
Bouwman RA
Bowrey S
Boxall L
Boyd C
Bradburn M
Bradley J
Branagan G
Branco T
Brand B
Brandsborg B
Breitenstein S
Brennan A
Brennan E
Brenner L
Brincat M
Briscoe R
Bristogiannis S
Brooke J
Brookes J
Brookes M
Brooks C
Broomby R
Brotto AF
Brown A
Brown CW
Brown G
Brown J
Brown J
Brown L
Brown R
Brown R
Browning J
Bruma D
Brunete T
Brunswicker A
Bryant H
Bua E
Buccimazza I
Buckley S
Buerkle C
Buhre W
Buhre W
Buhrer T
Builu PM
Buise M
Bullock C
Bunwarie B
Burns K
Burrows L
Burrows T
Burston B
Burtenshaw A
Burton M
Busuioc M
Butryn I
Butt G
Byrne K
Cabezuelo E
Cabral R
Cabral TDN
Cabrini L
Cacala S
Cai F
Cai Y
Cain H
Cairns C
Cakova V
Calderwood C
Callaghan M
Campbell D
Campbell D
Campbell D
Campbell G
Campbell G
Campbell K
Campbell M
Campbell T
Campey L
Camsooksai J
Cancho D
Candido K
Cang J
Cannavo M
Cao J
Cao Y
Cao Z
Cardellino S
Cardosa J
Cardoso G
Cardy J
Carmino L
Carp CP
Carr A
Carrera R
Carroll C
Carroll J
Caser E
Castano Moreira B
Castano B
Castle G
Cavanagh S
Cawthorn L
Cernea DD
Chaddock M
Chaloulis P
Chan A
Chan HMH
Chan M
Chan P
Chan V
Chan WK
Chan WKJ
Chan YL
Chande S
Chandler B
Chandra S
Chandrasekharan S
Chang YH
Chaniotaki F
Charitos E
Charlalampidoy A
Charles R
Chatterjee D
Chatterjee J
Chatzimichali CA
Chau S
Chazova E
Cheah C
Cheah S
Cheeseman M
Cheing Y
Chen C
Chen C
Chen F
Chen F
Chen H
Chen J
Chen J
Chen L
Chen L
Chen L-L
Chen P
Chen Q
Chen R
Chen S
Chen S
Chen S
Chen Y
Chen Y
Chen Y
Chen Y
Chen Z
Cheng B
Cheng KH
Cheng Z
Cheong E
Cherian R
Cherrett V
Chetty RR
Chew M
Chhabra A
Chicken D-W
Chilinciuc I
Chin II
Chirkut S
Chisbert Cuenca V
Chlorou D
Choi H-MD
Choi S
Chow L
Christian R
Christiansen IC
Christmas N
Christodoulidis G
Christodoulopoulou T
Christofaki M
Christoforidis D
Chronis C
Chu HM
Chu S
Chua P
Chukkambotla S
Chung CKE
Cifra E
Ciobanu C
Ciobotaru OR
Cirstea E
Clark R
Clarkson A
Clarkson R
Claxton A
Clemmons K
Cloro LM
Clyde A
Cobzaru I
Codita A
Colangelo A
Colangelo C
Colling K
Collins H
Collins M
Collins N
Colvin C
Commey T
Comptaer N
Conde C
Conradie A
Constantin K
Cook T
Cooper L
Cooper L
Cooper M
Cooper R
Cooper S
Copaciu E
Cope J
Copetti E
Copley E
Copotoiu SM
Coppens M
Corneci D
Cornell J
Cornish J
Correia da Silva RFM
Corti D
Costanzo E
Costelloe H
Cotter R
Cotterell S
Cotterill D
Coughlan E
Coulter I
Coulter S
Coutinho F
Cowton A
Cox H
Cozar OI
Craig J
Craven R
Craw N
Craw S
Creary T
Cripps H
Critchley R
Cronje L
Cruickshank R
Cruikshanks A
Cruz S
Cueva A
Cunha P
Curley G
Currow H
Czepanski C
Czeslick E
D'Andrea R
da Costa Fischer BF
Dafnios N
Dai H
Dai Q
Dai Q
Dai SY
Daikou P
Dalamagka M
Dalampini E
Dali-Kemmery L
Dalton E
Damant R
Daniel C
Daniel GD
Daniel H
Daniel H
Daniel S
Dankl D
Darko J
Darwish S
Das S
Dasrath A
Datson A
Daubeny T
Daugaard M
Davari M
Dave T
Davies C
Davies H
Davies K
Davies K
Davies L
Davies Z
Davis E
Davis F
Davis S
Daya B
De Andres Ibanez JA
de Araujo DM
De Baerdemaeker L
de Beer J
de Boer HD
De Bruyne A
de Campos Ferreira MF
de Fretes J
de Gasperi J
De Hert S
De Jongh K
De Kegel D
De Meyer JN
De Oliveira MC
de Rudnicki S
de Swardt M
de Vasconcellos K
de Villiers M
de Wet J
Deacon M
Deblaere I
Dedemadi G
Deen T
Deepak S
Deighton K
Deja M
Delgado Garcia DR
Delgado Navarro C
Della Rocca G
Dempsey G
Dempster A
den Hoedt M
Denham S
Dent K
Dermitzaki D
Desbordes J
Despotidis V
Diaconescu C
Dias F
Dias S
Dickson J
Ditai J
Divatia J
Dixon L
do Nascimento Junior P
Dobson G
Docherty P
Dodiyi-Manuel A
Dodsworth K
Dolan R
Dong B
Donohue R
Donovan A
Douglas J
Doumos R
Downes C
Doyle D
Dragnea D
Dragoescu NA
Drake M
Drimala M
Drinkwater Z
Drummond L
Du F
Du F
Du X
Duarte C
Dube NZ
Duca A
Dudgeon L
Dudson R
Duenser M
Dumitrascu CO
Dumitrescu A
Dunay A
Dunk N
Durant E
Durodola A
Dursin AN
Durst A
Duttchen K
Dutu M
Dwyer H
Dylst D
Dzhamullaev P
Dzulkipli N
Echem R
Edmond H
Edwards J
Edwards M
Edwards M
Efthymiadi A
Egan T
Eggleston C
Eichwalder A
Eikman J
Ekelund K
el Manser D
El-Sayed A
Elabib A
Elena G
Elferink-Vonk R
Elgasim M
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Ellis K
Elna C
Emma T
Endersby S
Eneje P
Eng K
English D
English R
Epodoi J
Eskildsen KZ
Esteves S
Ethgen S
Evans A
Evans C
Everingham K
Ewe R
Ezekiel E
Ezike H
Fagerlund MJ
Faina L
Falk E
Fan H
Fan L
Fan Y
Fanfani LC
Faponle F
Faria e Maia D
Faria F
Farid N
Farina Z
Farrell H
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Fasina O
Fatungase OM
Faulds M
Fei Y
Fellinger P
Feng Y
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Fernandez S
Ferrando C
Filipescu D
Filippopoulos A
Finch A
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ISOS ISOS
Iurin A
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Koulouras V
Koutelidakis I
Koutsikou A
Kowalski S
Kozompoli D
Krepil A
Kretov V
Krishnachetty B
Kruse C-H
Krystopchuk A
Kuan PX
Kubitzek C
Kuhn WP
Kulikov A
Kulkarni A
Kulkarni A
Kulkarni R
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kumar VR
Kumara P
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Kurnia A
Kusel BS
Kushakovsky V
Kwok A
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Kwok FY
Kyomugisha E
Kyparissi A
Ladha K
Laengle F
Laetsch B
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Lance M
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Landauer F
Landers AT
Landoni G
Lane R
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Larsen JR
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Lataniotou O
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Lee C
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Lena A
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Lenhart F-P
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Li B
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Liddle A
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Lignos L
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Lois F
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Looi JK
Looseley A
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Lopez del Moral O
Lopez AG
Lopez JCJA
Loumpias C
Lowery T
Lozano A
Lu B
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Lubach I
Lubnin A
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Lumsden R
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Luo D
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Marques Lobo FR
Marques Parra A
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Martinez Ernesto EP
Martins Costa ACM
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Martinson V
Mas A
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Olajumokex T
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Olonisakin RP
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Ou Y
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Pan Y
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Pande S
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Papadopoullos S
Papadopoulos D
Papageorgiou G
Papailia A
Papaioannou A
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Papapanagiotou I
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Rodrigues CM
Rodrigues RS
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Saad H
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Saiz C
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Sampson S
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Secher EL
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Socorro Artiles T
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Sukawi I
Sulaiman HA
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Zapata DDM
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Zoerner F
Zonneveldt H
Zou X
Zoulamoglou M
Zsisku L
Publication venue: 'Oxford University Press (OUP)'
Publication date: 01/01/2016
Field of study

BACKGROUND: As global initiatives increase patient access to surgical treatments, there remains a need to understand the adverse effects of surgery and define appropriate levels of perioperative care. METHODS: We designed a prospective international 7-day cohort study of outcomes following elective adult inpatient surgery in 27 countries. The primary outcome was in-hospital complications. Secondary outcomes were death following a complication (failure to rescue) and death in hospital. Process measures were admission to critical care immediately after surgery or to treat a complication and duration of hospital stay. A single definition of critical care was used for all countries. RESULTS: A total of 474 hospitals in 19 high-, 7 middle- and 1 low-income country were included in the primary analysis. Data included 44 814 patients with a median hospital stay of 4 (range 2-7) days. A total of 7508 patients (16.8%) developed one or more postoperative complication and 207 died (0.5%). The overall mortality among patients who developed complications was 2.8%. Mortality following complications ranged from 2.4% for pulmonary embolism to 43.9% for cardiac arrest. A total of 4360 (9.7%) patients were admitted to a critical care unit as routine immediately after surgery, of whom 2198 (50.4%) developed a complication, with 105 (2.4%) deaths. A total of 1233 patients (16.4%) were admitted to a critical care unit to treat complications, with 119 (9.7%) deaths. Despite lower baseline risk, outcomes were similar in low- and middle-income compared with high-income countries. CONCLUSIONS: Poor patient outcomes are common after inpatient surgery. Global initiatives to increase access to surgical treatments should also address the need for safe perioperative care. STUDY REGISTRATION: ISRCTN5181700

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Archivio istituzionale della ricerca - Università dell'Insubria

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Mortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection: an international cohort study

Author: Liza
- AP-HP) Bertrand Dousset (H\uf4pital Cochin
- APHP) Anne Thomin (H\uf4pital Trousseau
- ASST Rhodense) Carlo Corbellin (Ospedale Di Rho
- NYU Winthrop Hospital) Amir H Sohail (NYU Langone Health
- Xarxa Assistencial Universit\ue0ria de Manresa) Pablo Collera Ormazabal (Fundaci\uf3 Althaia
/ Columbia University Medical Center) Miriam Callahan (NewYork-Presbyterian
3 University Hospital) Bridget Egan (Tallaght
4 Lapolla Pierfrancesco
5 Spain: Eduardo E Rubio Susana Henriques (Hospital Garcia de Orta).
6 G\uf3mez Marcos
\u2013 IRCCS Francesca Gaino (Humanitas Clinical and Research Center
\u2013 Italy) 20089 Rozzano (MI)
\uc1ngel Hern\ue1ndez Bartolom\ue9 Miguel
A Aaraj Mahmoud
A Ayeni Funbi
A Bass Gary
A Benson Ruth
A Bozkurt Mehmet
A Breen Kerry
A Breen Kerry
A Breen Kerry
A Callcut Rachael
A Chung Eric
A Coughlin Patrick
A de Gheldere Charles
A De Marchi Joshua
A Elliott Jessie
A Fahey Brian
A Griffiths Ewen
A Griffiths Ewen
A Griffiths Ewen
A Guariglia Claudio
A Hirji Sameer
A Khalefa Mohamed
A Marra (Fondazione Policlinico Universitario Agostino Gemelli) Angelo
A Nguyen (Frankfurt University Hospital Truong
A Olson (Duke University Medical Center) Steven
A Raptis Dimitri
A Rollett Rebecca
A Saeed Samerah
A Salama Hiba
A Salamah Abdulrauf
A Schnitzbauer Andreas
A Schnitzbauer Andreas
A Singh Aminder
A Stevens Kent
A Stylianides Nicholas
A Thaha Mohamed
A Vega (12 de Octubre University Hospital) Viviana
A Vivas Alfredo
A Zappa Marco
Abate Emmanuele
Abdalaziz (Gloucestershire Royal Hospital) Hossam
Abdelkarim Mostafa
Abdou Hossam
Aboelkassem-Ibrahim Ahmad
Abuown Ala
Acebes-Garcia Fernando
Acharya Metesh
Adamina Michel
Addae-Boateng Emmanuel
Adolfo Pisanu (Cagliari University Hospital) Mauro Podda
Aftab Raiyyan
AG Moir John
Agarwal Arnav
AH Ibrahim Mohamed
Aitken (Queen Elizabeth University Hospital) Emma
Al-Azzawi Marwa
Al-Embideen Somya
Al-Sukaini Ahmad
Alakaloko Felix
Alam (Heartlands Hospital) Ruhina
Alameer Ehab
Alderson Derek
Ali Mohamed Ali (Queen Elizabeth Hospital King's Lynn) Inthekab
Aliyeva (Acibadem Mehmet Ali Aydinlar University Zumrud
Aljanadi Firas
Almasri Murad
Alonso Poza (Hospital Universitario del Sureste) Alfredo
Alonso-Ortu\uf1o Paula
Alser Osaid
Alser Osaid
Alser Osaid
Altintoprak (Sakarya University Faculty of Medicine) Fatih
Amalina Che Bakri Nur
Amjad Rabbia
Anania Gabriele
and Westminster Hospital NHS FT and Imperial College London) Chelsea
Andabaka Tatjana
Andrea Pisani Ceretti (ASST Santi Paolo e Carlo) Nicol\uf2 M Mariani
Angelou Dimitrios
Anita Volpe (New York Presbyterian Queens) Stephen Merola
Annamalai Seethalakshmi
Annessi Valerio
Anthoney James
Anuradha R Bhama (Rush University Medical Center) Alfonso Torquati
Anwar Sibtain
Aragon-Chamizo Juan
Ardito Antonella
Arigoni Michele
Armao Teodora
Arminio (Ospedali Riuniti Azienda Ospedaliera Universitaria Foggia) Armando
Armstrong Lara
Asaad Peter
Ashcroft James
Ashmore Christopher
Asqalan Ahmad
Asti (IRCCS Policlinico San Donato Emanuele
Aubry Emmanuelle
Aytac Erman
Ayuso-Herrera Esther
Azerbaijan:Elgun Samadov Joana FF Simoes (Chair). 2 Collaborators: (denotes Local Principal Investigator) Algeria: Faraj S Almaadany (\uc9tablissement Hospitalier Sp\ue9cialis\ue9 en Canc\ue9rologie - Centre Pierre-et- Marie-Curie).
B Avellana Rocio
B Catton Andrew
B Fonsi Giovanni
B Hing Caroline
B O'Meara Lindsay
B Schaffer Kathryn
B Yousuf (Tobruk Medical Center) Farhat
B\ue0mbina (Fabrizio Spaziani Hospital Fabrizio
Bailon-Cuadrado (Hospital Universitario R\uedo Hortega) Martin
Baldi Caterina
Baldini Edoardo
Baldo (Ospedale Santa Corona Stefano
Ballabio Michele
Baloyiannis Ioannis
Baltazar Gerard
Bandiera Alessandro
Barlow Emma
Barmasse (Ospedale Regionale Umberto Parini) Roberto
Barmpagianni Christina
Baronio (Policlinico San Pietro) Gianluca
Barra Fabio
Bartholomew's Hospital) St
Bartsch Anne-Marie
Basgaran Amedra
Basha Amr
Bashkirova (North Middlesex University Hospital) Varvara
Bastazza Marco
BB Sullivan (The Royal London Hospital) Tom
Beak Philip
Belcher Elizabeth
Belgium: Gabrielle H van Ramshorst Sevda Jafarova (Leyla Medical Center).
Beltr\ue1n de Heredia Juan
Belvedere Angela
Ben\uedtez-Linero Inmaculada
Benjamin Franklin) Campus
Bergeat Damien
Bernasconi Matteo
Bhalla Ashish
Bhangu Aneel
Bianco Federica
Bisagni Pietro
BJ Borgstein Alexander
Blake (Southport and Formby District General Hospital) Iain
Blanco-Colino Ruth
Blazquez-Martin (Hospital Principe De Asturias) Alma
Boal Matthew
Bologna) Ausl
Bonavina Giulia
Bonavina Luigi
Bond-Smith Giles
Booth (Freeman Hospital) Karen
Borges Filipe
Borghi Felice
Borja De Lacy (Hospital Clinic Barcelona) F
Bourke Grainne
Boyle Emily
Brachini Gioia
Brain Jessie
Brar Amanpreet
Breckles Lisa
Brendan L Skelly (Altnagelvin Area Hospital) Catherine Rossborough
Brianza) Carate
Brixton Genevieve
Bruzzaniti Placido
Bueser Teofila
Burnside Nathan
C Bosanquet David
C Brown (Manchester University NHS Foundation Trust Benjamin
C De Souza Anthony
C Glasbey James
C Glasbey James
C Hopkins James
C Lauscher Johannes
C McIntyre Robert
C Mckay Siobhan
C Neary Paul
C Nugent III William
C Rodriguez-Sanjuan (Marqu\ue9s de Valdecilla University Hospital) Juan
C Roslani April
C Tucker Sarah
C Velmahos (Massachusetts General Hospital) George
C Winter Stuart
Caballero Albert
Cairo University) Mahmoud MA Elfiky (Kasr Alainy Faculty of Medicine
Calcerrada-Alises Enrique
Camacho Fern\ue1ndez-Pacheco (Complejo Hospitalario Universitario Insular-Materno Infantil) Borja
Camarero Enrique
Campagnaro Tommaso
Campanelli Michela
Candiani Massimo
Cannoletta (Royal Brompton Hospital) Marina
Cantalejo-Diaz (Hospital Universitario Miguel Servet) Miguel
Cao Han
Capizzi Vita
Carcano (Ospedale di Circolo Giulio
Carissimi Francesca
Carlini Massimo
Carlos Bernal-Sprekelsen Juan
Carlos Catal\ue1 Bauset (Consorcio Hospital General Universitario) Juan
Carlucci Michele
Carmela Giuffrida Maria
Carmichael Heather
Carrasco Milagros
Carrillo Mariana
Carvello Michele
Casati Massimiliano
Castoro Carlo
Castro Ruiz Carolina
Catalan Vanesa
Catriona R Luney (Nuffield Orthopaedic Centre) Benjamin JF Dean
Cavaleiro Salom\ue9
Cellerino Paola
Center Amsterdam) Cancer
Centinaio (Ospedale Maggiore di Lodi) Giovanna
Cernei Cristina
Cervellera Maurizio
Chakrabortee Sohini
Chamberlain Stephanie
Chan Jeffrey
Chang Grace
Chaudhry Daoud
Chebaro Alexandre
Chen (Jamaica Hospital) David
Chetty Govind
Chia (Royal Derby Hospital) Zoe
Chiappini Ambra
Chiarugi (Azienda Ospedaliero Universitaria Pisana) Massimo
Chidambaram Swathikan
Chiozza Matteo
Cholewa Hanna
Chong (Evelina London Children's Hospital) Clara
Choolani-Bhojwani Ekta
Christian Cotsoglou (ASST Vimercate) Stefano Granieri
Chui Karen
Chung Choyin
Cirillo Bruno
Citterio Davide
Clermidi Pauline
Coccolini Federico
Colletti Gaia
Compagnoni Bruno
Concepci\uf3n-Mart\uedn Vanesa
Confalonieri Marco
Connolly Hannah
Conso Christel
Conti Luigi
Cooper Zara
Corral Javier
Costa Marta
Costanzi Andrea
Cox Daniel
Cozza Valerio
CR Wormald Justin
Croatia: Jakov Mihanovic Nicolas Duchateau (Heilig Hart Ziekenhuis Lier).
CS Clough Ethan
Cuming Tamzin
Cuneo)
Curtis Miles
Cuschieri Joseph
D Baron Ryan
D Bosch Karen
D Brown Oliver
D Bueno-Ca\uf1ones Alejandro
D Cato Liam
D Drake Thomas
D Jenkinson Michael
D Jenkinson Michael
D Liyanage Aloka S
D Pinkney Thomas
D Rajgor Amarkumar
D Stewart Grant
D Tebala Giovanni
D'Agruma Michele
D'Andrea Giancarlo
D\uedaz P\ue9rez David
D\uedaz-Garc\ueda (Hospital Universitario Nuestra Se\uf1ora de Candelaria) Alberto
Da Roit Anna
da Saliceto\u201d Patrizio Capelli (Ospedale \u201cG.
Dare Oliver
Darko Ebenezer
Data Monitoring and Ethics Committee: Deborah S Keller H. Hunt Batjer (University of Texas Southwestern).
Day Andrew
De Andr\ue9s-Asenjo Beatriz
de Medicina Facultad
De Miguel-Ardevines Maria-Carmen
De Nardi Paola
De Simone Veronica
De Toma Giorgio
Deepti Sinha (University College London Hospital) Nicholas Kalavrezos
Dehal (Kaiser Permanente Panorama City Medical Center) Ahmed
Dehart Dustin
Del Giudice Roberto
Delgado-Oliver Eduardo
Denmark: Henry G Smith Bernarda Bakmaz (Zadar General Hospital).
Denning Max
Desai Anant
Desender (Ghent University Hospital) Liesbeth
Dester (ASST Valcamonica Ospedale di Esine) Sara
Di Candido Francesca
Di Chiara Francesco
Di Franco Gregorio
Di Giuseppe (Ente Ospedaliero Cantonale del Canton Ticino) Matteo
Di Saverio Salomone
Di Saverio Salomone
Di Saverio Salomone
Di Saverio Salomone
Diaz-Pe\uf1a Patricia
Dieguez Fernandez Beatriz
Dissemination Committee: Michel Adamina Aneel Bhangu.
Dolores Del Toro M
Domodossola
Doussot Alexandre
Duff Sarah
Dunning Joel
Dunstan Matt
Duque-Mallen Victoria
Dziakova Jana
E Canova Michaela
e Carle Hospital Chiara Peluso (Santa Croce
e Carlo ASST Santi Paolo
E Dawson Brett
E Dickson Kathryn
E Hudson Victoria
E Jenny (Johns Hopkins Hospital) Hillary
E Lewis Sophia
E Nita George
e Oftalmico) Giulio Iacob (Ospedale Fatebenefratelli
E P\ue9rez-S\ue1nchez Luis
E Rice Henry
E Ssentongo Anna
e Universit\ue1rio de Coimbra) Ana C Almeida (Centro Hospitalar
E Xyda Souzana
Edward Fitzgerald J
EF Abbott Tom
EF Abbott Tom
Egan Richard
Egypt: Mohamed El Kassas University of Copenhagen).
El Youzouri Hanan
El-Ali (Queen's Hospital Abess
Elaine YL Leung (The Pan Birmingham Gynaecological Cancer Centre) Sudha Sundar
Elfeki Hossam
Elhadi Muhammed
Eljareh (Aljalaa Hospital) Mohammed
Elkadi Hannah
Elkady Ramy
Elkhafeefi Fatimah
Elmore Ugo
Elmoslemany (The Walton Centre NHS Foundation Trust) Tarek
EM Bouhuwaish Ahmad
EM Brathwaite Collin
Emmerson (North Manchester General Hospital) Oliver
Enemosah Ibrahim
English Camilla
English William
Ereidge Simon
Escartin Jorge
Estaire-Gomez Mercedes
EuroSurg
Evans (Queen Elizabeth the Queen Mother Hospital Margate) Jessica
Exley Rebecca
F Bath Michael
F Cunha Miguel
F Cunha Miguel
F Davis Niall
F Ridgway Paul
Fabbri Nicol\uf3
Falco Giuseppe
Familiari Pietro
Fancellu (Cliniche San Pietro Alessandro
Fanjul G\uf3mez Mar\ueda
Farik Shebani
Farr\ue9 Font Roser
Farrell Tony
Fehervari Matyas
Fell Adam
Fern\ue1ndez- Mart\uednez Mar\ueda
Fern\ue1ndez-Gomez Cruzado (Hospital Urduliz) Laura
Fern\ue1ndez-Mar\uedn Reyes
Fernandez-Camu\uf1as Angel
Ferrara)
Ferrara Francesco
Ferrari Guglielmo
Ferrero Simone
FF Simoes Joana
FF Simoes Joana
Findlay Laura
Fiore Marco
Fiore Marco
Fiori Enrico
FJ Dunne Declan
Flatman Michael
Flindall Ian
Fontana (Vittorio Emanuele Tommaso
Ford (The Robert Jones and Agnes Hunt Orthopaedic Hospital) David
Ford Samuel
Forlani Stefano
Fr\ue9d\ue9ric Bretagnol (H\uf4pital Louis-Mourier - GHU AP-HP. Nord - Universit\ue9 de Paris) David Moszkowicz
France: Zaher Lakkis Mohamed Sherief (MISR Cancer Center/MISR International Hospital).
Francisco de Vitoria Universidad
Francone Elisa
Frattaruolo Colomba
Frio (Institute of Neurological Sciences of Bologna Federico
Frosinone)
G Aoun Salah
G Barranquero Alberto
G Blazer III Dan
G Collins Chris
G Edwards John
G Edwards John
G Morton Dion
G Povey Meical
G Velopulos Catherine
G Wade Ryckie
Gabriel Kinnaman (IU Health Methodist Hospital) Ashley D Meagher
Gagliano Annalisa
Gagliardi Filippo
Gahunia Sukhpreet
Gala Tanzeela
Galfrascoli Elisa
Galimberti Luca
Galindo Jara (Hospital Universitario de Torrej\uf3n Pablo
Gallagher Phoebe
Galleano Raffaele
Gallo Gaetano
Gallo Gaetano
Gallo Gaetano
Galv\ue1n-P\ue9rez Armando
Gamal Amira Ibrahim Sallam
Gammeri Emanuele
Ganau Mario
Garc\ue9s-Garc\ueda Ra\ufal
Garcia Fernandez Andres
Garcia-Conde Delgado Maria
Garulli (Ospedale Infermi di Rimini) Gianluca
Gascon-Ferrer Isabel
Gattolin (Regina Montis Regalis Hospital Andrea
Gaujoux Sebastien
Gentilli Sergio
Georgiades Fanourios
Germany: Carsten Kamphues Didier Ollat (Institut Mutualiste Montsouris).
Gerogiannis (Kingston Hospital NHS Foundation Trust) Ioannis
Ghanbari (Homerton University Hospital) Amir
Ghosh Dhruv
Giacometti Marco
Giblin Anna-Victoria
Gilbert (Surrey and Sussex Healthcare NHS Trust) Catherine
Gim\ue9nez Clara
Giorgakis Emmanouil
Gipponi Manuel
Glen Paul
GlobalPaedSurg GlobalSurg
Goatly Giles
Gobatti (San Carlo Borromeo Hospital Davide
Godbole Chintamani
Gohil Kajal
Gomez-Rosado Juan-Carlos
Gonullu Emre
Gonzalez-De Miguel Melania
Gonzalez-Gonzalez Enrique
Gordini Luca
Gracia Isabel
Gracia-Roche Carlos
Greece: Konstantinos Bouchagier Markus W L\uf6ffler (University Hospital Tu\u308bingen).
Green Susanna
Grivon Manuela
Grove (Department of Colorectal Surgery Thomas
Guaglio Marcello
Guaitoli (Perrino) Eleonora
Guglielmi Alfredo
Guha Soumya
Gustavino (Unit of Obstetrics and Gynecology IRCCS Ospedale Policlinico San Martino Genoa) Claudio
Guti\ue9rrez Samaniego Mar\ueda
H Babu Bheemanakone
H Chowdhury Abeed
H Davidson Giana
H Davidson Giana
H Davidson Giana
H Elfallal Ahmed
H Emile Sameh
H Kirmani Bilal
H Liu Helen
H Murphy Suzanne
H van Ramshorst Gabrielle
H\uf6lzle Frank
Habeeb Amir
Hagger Robert
Hakmi Hazim
Halkias Constantine
Halkias Constantine
Hampton (Rotherham District General Hospital) Matthew
Handa Siddhartha
Haq Iram
Harky (Liverpool Heart and Chest Hospital) Amer
Harries (Morriston Hospital Rhiannon
Harrison Joseph
Hasan Raashad
Hawari Mohammad
Hawkin Paul
Hebblethwaite Bethany
Helier University Hospitals NHS Trust) St
Heritage Emily
Hernandez Garcia Miguel
Hernandez-Juara Pilar
Herrero-Lopez Maria
Hervieux Erik
Heyd Bruno
Higgs Simon
Hitchman (Hull University Teaching Hospitals NHS Trust) Louise
Ho Beatrice
Hogan Aisling
Hospital of Varese University
Hospital Universitario del Henares) Miguel Angel Garcia-Ure\uf1a (Universidad Francisco de Vitoria
Hospital) Atakent
Hospital) Wythenshawe
Hossain Tanvir
Houston Roy
Hurt Libor
HV Byrne Matthew
i Pujol) Alba Zarate (Hospital Germans Trias
I Roxo (Brigham and Women's Hospital) Vanessa
I van Berge Henegouwen (Amsterdam UMC Mark
I Alessandro Di Bartolomeo (Policlinico Umberto
Iannone Immacolata
Ibrahim Sherif
Iovino Domenico
Ireland: Arnold DK Hill Paraskevi Tourountzi (Kavala General Hospital).
Isik Arda
Israel: Oded Zmora Thomas M Aherne (Galway University Hospital).
Italy: Maurizio Zizzo Nadav Kugler (Shamir Medical Center).
J Abbott Sarah
J Baker Olivia
J Baldwin Alexander
J Beamish Andrew
J Carlos William
J Caruana Edward
J Caruana Edward
J Davies Emma
J Diaz Jose
J Doe Matthew
J Eardley Nicola
J Fern\ue1ndez Antonio
J G\uf3mez D\uedaz Carlos
J Hainsworth Alison
J Hall Bria
J Holme Thomas
J Hutchinson Peter
J Hutchinson Peter
J Kalkwarf Kyle
J Lin Daniel
J Lowery Aoife
J McCluney Simon
J Mehigan Brian
J Mills Sarah
J Pachl (Birmingham Children's Hospital) Max
J Rogers Luke
J Ryan \uc9anna
J Scurrah Rachel
J Shackcloth Michael
J Smart Neil
J Steinkamp Pieter
J Tejero-Pintor Francisco
J Thomas Amy
J Torres Antonio
J Warren Oliver
J Warren Oliver
J Williams Katherine
James RW Hall (Stepping Hill Hospital) Claire Hall
James's Hospital) Conor P Barry (St.
Jamil Tahir
Jayaraju (University Hospital of Wales) Ullas
Jenner Edward
JG Chase Thomas
Jha Shane Lester (James Cook University Hospital) Madan
Jimenez-Higuera Elisa
Jimeno Jaime
JM Dunne Naomi
JM Ferguson Henry
Jo\ue3o Lima Maria
Johnstone Jack
Jones Mark
Jordan: Mahmoud Al-Masri Gela).
JS Wall Joshua
Judkins Nicholas
JW Wilkin Richard
K Abou Chaar Mohamad
K Ambler Graeme
K Bankhead-Kendall Brittany
K Bankhead-Kendall Brittany
K Bankhead-Kendall Brittany
K Brown Allison
K Fusai Giuseppe
K Gill Charn
K Kamarajah Sivesh
K Patel Panna
K Ubhi Harmony
K Weerasinghe Chamindri
K\uf6nigsrainer Alfred
Kalidindi Venugopala
Kamal Mona
Kang Chong
Kara Yasin
Karam Edward
Karim Ahmed
Kashora Florence
KC Jonker (University Medical Center Groningen (University of Groningen) Pascal
Kearney (Beaumont Hospital) David
Khajuria Apoorva
Khan Azam
Khan Umul
Khatri Chetan
Kinross James
Kler Aaron
Klimopoulos (Evangelismos General Hospital) Serafeim
Kocata\u15f (Kanuni Sultan Suleyman Training and Research Hospital) Ali
Kolias Angelos
Kolias Angelos
Kontovounisios Christos
Kourdouli (Leicester Royal Infirmary) Amar
Krishnan Emily
Kristinsson Sverrir
Kruijff Schelto
KS Viswanath Yirupaiahgari
Kudsk-Iversen S\uf8ren
Kufeji Dorothy
Kulkarni Rugved
Kurihara Hayato
L Biffl Walter
L Coleman Natasha
L Collins Michelle
L Engel (Temple University Hospital) Jamie
L Fowler Amy
L Garcia Galocha Jose
L Hughes Jane
L J\uf6nsson (Bispebjerg Hospital Maria
L Labib Peter
L Marsh (Scripps Memorial Hospital) Christopher
L McKevitt Kevin
L Osorio Alexander
L Romera Jose
L Serevina Olivia
L Venn Mary
L Venn Mary
L Venn Mary
L Wright Franklin
L Young Alastair
L\ue1zaro Andr\ue9
La Torre Filippo
Laface (Ospedale Vittorio Emanuele III Letizia
Lami Mariam
Landaluce-Olavarria Aitor
Laura Hansen 9
Lawani Ismail
Lawday (Southmead Hospital) Samuel
Lawday Samuel
Le Roy Bertrand
Lecco) Asst
Lecolle Katia
Lederhuber Hans
Lederhuber Hans
Leeds)
Leicester)
Leventoglu Sezai
Li Elizabeth
Li Elizabeth
Li Zoe
Libya: Ghadah Z Alkadeeki Hani Al-Najjar (King Hussein Cancer Center).
Liew Ignatius
Ligure (SV) Pietra
Lima Buarque Igor
Lisi Giorgio
Lizzi Vincenzo
Lo Terence
Lombardia) Regione
Lomiento Daniele
Longhi Marco
Lopez Antonanzas (Hospital Clinico San Carlos Leyre
Losada Ruiz Manuel
Lostis Emilie
Lostoridis Eftychios
Loubani Mahmoud
Lowy- Benoliel Alejandro
Lucianetti (Papa Giovanni XXIII Hospital) Alessandro
Luigi MP Marino Cosentino (PO San Filippo Neri - ASL ROMA 1) Andrea Sagnotta
luis Blas Laina Juan
Luke Evans (Norfolk and Norwich University Hospital) Mina MG Youssef
Luke Louis
Lunevicius Raimundas
Luraghi Marco
Lye George
M Alrahawy (Menofiya University Hospital) Mahmoud
M Andreani Stefano
M Ashoush Fouad
M Bajomo Oreoluwa
M Blundell Chris
M Cicerchia Pierfranco
M Connolly Tara
M Diez-Alonso Manuel
M Dur\ue1n-Mu\uf1oz-Cruzado (Hospital Universitario Virgen del Rocio) Virginia
M Emslie Katy
M Harrison Ewen
M Holbrook Charlotte
M Isolani Simone
M Keatley James
M Leite-Moreira Andr\ue9
M Mithany Reda H
M Mohan Helen
M Mohan Helen
M Monteiro Joana
M Morgom (Tripoli Central Hospital) Marwa
M Muguerza Jose
M Nunes Quentin
M Nygaard Rachel
M Omar Aneel Bhangu Omar
M Philp Matthew
M Pollok Joerg
M Rooney Siobhan
M Sampietro Gianluca
M Sewards Joseph
M Tang Alethea
M Trout Isobel
M Walters (Harborview Medical Center Andrew
MA Kaafarani Haytham
MA Kaafarani Haytham
MA Kaafarani Haytham
Maarten van Heinsbergen (VieCuri Medisch Centrum) Joop Konsten
Mabrouk Islam
Macchi Alberto
MacDonald Luisa
Machairas (Royal Free Hospital) Nikolaos
Madonini Marco
Madrid)
Madrid)
Magalh\ue3es Maia Mariana
Magne Augestad Knut
Magowan Drew
Maha H Haqqani (Boston Medical Center) Frederick T Drake
Maisonneuve Emeline
Majkowska Agata
Majkowski (Northern General Hospital Lawrence
Mak (Queen Elizabeth Hospital Birmingham) Jason
Malabarba Stefano
Malerba Michele
Maninder Kalkat 7
Mannan Syed
Manson Joanna
Mansuri Ahmer
Mantoglu (Sakarya University Research and Educational Hospital) Baris
Manu Nichola
Manzoni 56 Via
Maqsood Afnan
Marano Alessandra
Marchbank Adrian
Marcos-Santos Pablo
Marinos Kouris (Buckinghamshire Healthcare NHS Trust) Spyros
Marqueta De Salas Maria
Marrano Enrico
Mart\uedn-Rom\ue1n Lorena
Mart\uednez P\ue9rez Carolina
Mart\uednez-dePaz Fernando
Martel Lozano Saida
Martin (St Mary's Hospital) Guy
Martin Emmeline
Martin Janet
Martin-Albo Lorena
Martine Uittenbogaart (M\ue1xima Medical Center) Wouter KG Leclercq
Martinelli Fabio
Martinez-German Antonio
Martinez-Pinedo Carlos
Martins Ricardo
Marwan Hisham
Marzi Federica
MAS Baig Mirza
Mateos-Sierra (Hospital General Universitario Gregorio Mara\uf1\uf3n) Olga
Mater Studiorum University of Bologna) Alma
Mathieu (CHU Besan\ue7on) Pierre
Matute-Najarro Maria-Soledad
Maw Andrew
Mazingi Dennis
Mazzaferro (Fondazione IRCCS Istituto Nazionale dei Tumori Vincenzo
McCanny (Antrim Area Hospital) Andrew
McKenzie Katherine
McLarty (Northumbria NHS Hospital Trust) Nicola
McPherson Iain
Medina Esther
Mediratta Saniya
Medone Marzia
Mehra (Guy's and St Thomas\u2019 NHS Foundation Trust) Gautam
Mele Simone
Melero-Cort\ue9s Lidia
Melody Baeza (Morales Meseguer University Hospital) Jos\ue9 Aguilar
Mendon\ue7a Ata\uedde Gomes Gustavo
Mendoza-Moreno Fernando
Meneghini Simona
Merate
Mercante Giuseppe
Merdrignac (Rennes University Hospital) Aude
Metallidis Symeon
Michel (Pinderfields Hospital) Martin
Migliore Marco
Milan)
Milan)
Milan)
Miller Douglas
Minaya- Bravo Ana
Minaya-Bravo Ana
Minaya-Bravo Ana
Minaya-Bravo Ana
Mingoli Andrea
Minto Gary
Mirabella Antonello
Misra Nikhil
Mitrasinovic Stefan
Miu Victor
Moawad (Royal Victoria Hospital) Nader
Mochet Sylvie
Modabber Ali
Mohammad Adam
Mohan Midhun
Moliner-S\ue1nchez Carmen
Mondov\uec)
Mongelli Francesco
Monteleone (Ospedale San Leopoldo Mandic Michela
Montuori Mauro
Moore Rachel
Mora-Guzm\ue1n (Hospital Santa B\ue1rbara) Ismael
Morales Dieter
Morales Xavier
Morelli Luca
Morelli Lucia
Morgan Richard
Morris Chris
Mortini Pietro
Mosca Angelo
Moszkowicz David
Moszkowicz David
Motter Dema
Moug Susan
Mukherjee Samrat
Munoz Rivas Ana
Murcia)
N Bence Matthew
N Hopkinson David
N Mashbari Hassan
N Mashbari Hassan
N Mashbari Hassan
N Naumann David
N Rao Jagan
N Townshend David
N\ufa\uf1ez Jordi
Najdy Manhal
Nakas (Glenfield Hospital Apostolos
Namazov Ilgar
Naredla Pradyumna
Nasef Emmhamed
Nassa Heeam
Nath Rahul
Navarro-S\ue1nchez Antonio
Nazarian (Bupa Cromwell Hospital) Scarlet
Neal Bhutiani (University of Louisville Hospital and Norton Hospital) Robert CG Martin
Negri Giampiero
Nehra Deepika
Neil-Dwyer Jason
Nepogodiev Dmitri
Nepogodiev Dmitri
Nepogodiev Dmitri
Neri Jacopo
Netherlands: Suzanne S Gisbertz Mustafa R Bulugma (Zawia Teaching Hospital). Mexico: Fernando Cordera (ABC Medical Center).
Newton (Manchester Royal Infirmary) Katy
Nikaj (Azienda Ospedaliero Universitaria Maggiore della Carit\ue0 Herald
Niquen Milagros
Nobile (Azienda Ospedaliera Universitaria Integrata di Verona) Sara
Nogueiro Jorge
Nogues Pevidal (Royo Villanova) Ana
Novara)
Ntirenganya Faustin
Nugent Michael
O Ademuyiwa Adesoji
O Kavanagh Dara
O Larkin John
Oca\uf1a Juan
of Amsterdam University
of Ferrara) University
of Insubria University
of Milan) University
of Surgeons in Training (ASiT) Association
of Surgery) Department
of Washington) University
Okafor Barbara U.
Okechukwu Valentine
Oliva-Mompean (Hospital Universitario Virgen Macarena) Fernando
Oliveira Ana
OM Abdalla Mutwakil
Omar M Omar
OO Ayorinde John
Osagie-Clouard (Epsom &amp
Osman (Walsall Manor Hospital) Khabab
Ottolina Jessica
Ourieff (Mount Sinai Hospital) Jared
Outani Oumaima
Oyewole Bankole
P Arnaud Alexis
P Arnaud Alexis
P Arnaud Alexis
P Baker Markus
P Belgaumkar Ajay
P Boddy Alexander
P Duffy (Nottingham City Hospital) John
P Evans Jonathan
P Hazelton Joshua
P Jones Andrew
P Jones Robert
P Joyce Doireann
P Kisiel Aaron
P Pezzuto Anna
P Singh Rabindra
P\ue9rez-Gonz\ue1lez Marta
P\ue9rez-Saborido Baltasar
Pacheco-Sanchez David
Padilla-Valverde (Hospital General Universitario De Ciudad Real) David
Pai (Hammersmith Hospital) Madhava
Paiella Salvatore
Paisley (Brighton and Sussex NHS Trust Samuel
Palermo)
Palini Gianmarco
Palmeri Matteo
Parente Alessandro
Parlanti Daniele
Parmar Chetan
Pascual Angela
Pata Francesco
Pata Francesco
Patel Mahul
Pathak Abhijit
Patil Sangram
Pattyn Piet
Peckham- Cooper Adam
Pedram Panahi (University Hospitals Plymouth NHS Trust) Mariam Rela
Pedrazzani Corrado
Pellino Gianluca
Pereira Andr\ue9
Pereira-Neves Ant\uf3nio
Perez-Diaz Md
Perivoliotis (General University Hospital of Larissa) Konstantinos
Perkins Clare
Perotto (CHU Saint Etienne) Ornella
Perra Teresa
Petrone Patrizio
Phenix George
Piacenza)
Picazo Sara
Picon-Rodriguez Rafael
Piloni Martina
Pingarr\uf3n-Mart\uedn Lorena
Pinotti Enrico
Pizzini Paolo
PM de Vries Jean-Paul
Pockney Peter
Podolsky Dina
Poggioli Gilberto
Pompili Cecilia
Pontari Michael
Porcu Alberto
Portugal: Hugo Santos-Sousa Pakistan: Mariyah Anwer (Jinnah postgraduate medical center).
Potter (Royal Bournemouth Hospital) Ryan
Price Claire
Prita Daliya 8
Pruvot (Lille University Hospital) Fran\ue7ois-Ren\ue9
PTSurg ItSURG
Pujol-Muncunill Roger
Puppo Andrea
Q Mehdi (University of Texas Medical Branch) Mohammad
Quante Markus
Quintana-Villamandos Bego\uf1a
Qureshi Ali
R Burke Joshua
R Davidson Brian
R Dixon Jan
R Fretwell Kenneth
R Gujjuri Rohan
R Gujjuri Rohan
R Kowal Mikolaj
R O\u2019Neill John
R Sarma Diwakar
R Spalding Duncan
R Springford Laurie
Rachel Baumber (Royal National Orthopaedic Hospital) James T Parry
Radenkovic Dejan
Rahman Saad (Medway Maritime Hospital) Abdel
Rakvin Ivan
Ramallo-Sol\ueds Irene
Ramcharan Sean
Ramos Diego
Ramos-Bonilla Antonio
Ramos-De la Medina Antonio
Ramzi Joussi
Rathinam Sridhar
Rausa Emanuele
Ravaioli Matteo
Ravindran Sharanya
Raymond (Royal Lancaster Infirmary) Thomas
Razik Aisha
Redfern (Furness General Hospital) Jennifer
Reguera-Rosal Julio
Rey-Biel Juan
Rey-Valcarcel Cristina
RG Sheel Andrea
Ribolla Marta
Richards Tomos
Richmond (University of Maryland Medical Center) Michael
Righini (Ospedale del Delta Erminio
Rio-Gomez Javier
Riuniti Villa Sofia-Cervello Ospedali
Riyat Harjoat
Rizvi Sana
Roberts Keith
Roberts Matthew
Robertson (University Hospitals Coventry and Warwickshire) Stuart
Robertson (University of Arkansas for Medical Sciences) Ronald
Robin-Valle Alvaro
Rochon Melissa
Rojo Mikel
Rolli Luigi
Romano Silvio
Rome)
Romford)
Ross Elizabeth
Ross Howard
Rottoli Matteo
Royal Hospital) Princess
Ruiz (Hospital General Universitario Reina Sof\ueda Miguel
Ruiz- Grande Fernando
Ruiz-Martin (Rey Juan Carlos University Hospital) Irene
Ruiz-Soriano (Hospital Cl\uednico Universitario de Valladolid) Mar\ueda
Ruzzenente Andrea
Ryska Ondrej
S Abdelaal (Alexandria Main University Hospital) Ahmed
S Al Maadany Faraj
S Faria Carlos
S Hammond John
S Hossain Fahad
S Jeyaretna Deva
S Jones Conor
S Khan (Queen Alexandra Hospital) Jim
S Moura Francisco
S Ng-Kamstra Joshua
S Sica Giuseppe
S Tamimy Muhammad
S Wadley Martin
S\ue1nchez- Arteaga Alejandro
SA Taher Ahmed
Saez Carlos
Sahnan Kapil
Sahni Arun
Salim Ali
Salvia Roberto
Sammarco Giuseppe
Sampaio-Alves Mafalda
San Miguel-Mendez Carlos
Sanchez del Pueblo Cristina
Sanchez-Fuentes Maria-Nieves
Sanchez-Pelaez Daniel
Sanchez-Perez Coral
Sanchez-Rubio Maria
Sancho-Muriel Jorge
Sanchon Fructuoso Lorena
Sanders Julie
Santero-Ramirez Maria-Pilar
Santora Thomas
Santoro Antonio
Santos Irene
Sapienza Paolo
Sartarelli (Sant\u2019Orsola Hospital Lodovico
Sarveswaran Janahan
Sasia Diego
Sassari) A. O. U.
Saudemont Alain
Saudi-Moro Sef
Saxena Dolly
Saxena Shobhit
Sayasneh Ahmad
Scalabre Aurelien
Schache Andrew
Schiavina Riccardo
Schineis (Charit\ue9 University Medicine Christian
Schreckenbach Teresa
Scorza Antonella
Scott Lucy
Seegert (ProMedica Toledo Hospital) Sara
Seguin-Givelet Agathe
Senent-Boza Ana
Serrano Gonz\ue1lez Javier
Sette Laghi Asst
Seymour Keith
Shabana Amanda
Shah (The Whittington Hospital) Sujay
Shah Jigar
Shah Karishma
Shah Preena
Shakir Taner
Shalaby (Mansoura University Hospital) Mostafa
Shankar (Oxford University Hospitals NHS Foundation Trust Sushma
Shaw Richard
Sheffield)
Shehata Sameh
Shelley Hwang E.
Shen Ban Vin
Shenfine Amy
Sheridan Kelda
Sherief Ahmed
Sherif Mohamed
Shinkwin Michael
Shu Sebastian
Siaw-Acheampong Kwabena
Sileri (San Raffaele Scientific Institute Pierpaolo
Singh Abhinav
Singh Shailendra
Sinha Sanjay
Siragusa (Policlinico Tor Vergata Hospital Leandro
Sivaprakasam Rajesh
Sivayoganathan Sriharan
SJ Ledesma Frances
Smillie Robert
Smith (Countess of Chester Hospital) Claire
Smith Andrew
Smith Christopher
Sochorova (Royal Liverpool University Hospital) Dana
Society of Coloproctology (ESCP) European
Society of Colorectal Surgery (SICCR) Italian
Soggiu Fiammetta
Sohrabi (St Bartholomew's Hospital) Catrin
Sohrabi (Whipps Cross University Hospital) Catrin
Sohrabi Catrin
Solari (Royal Gwent Hospital) Francesca
Solli Piergiorgio
Soreide Kjetil
Soto Montesinos Cristina
SpainSurg
Spinelli Antonino
Spinelli Antonino
Spoletini (Sant'Eugenio Hospital) Domenico
Spriano Giuseppe
Sravanam Sanskrithi
Ssentongo (Pennsylvania State University) Paddy
Stanger Sophie
Stavroulias Dionisios
Steel (Sunderland Royal Hospital) Ben
Stella Marco
Stewart Robbie
Stringer Sally
Sudan: Osman M Ali Elima P Cagigal- Ortega (Hospital Universitario Severo Ochoa).
Sulen Nina
Sundar Sudha
Sundhu (Aintree University Hospital) Matthew
Surgical Research Collaborative (ISRC) Irish
Suri (University of California Davis Health Avni
Swansea)
Switzerland: Dimitri Christoforidis Ali A Ali karar (Al-rajhi).
Syed Arooj
Szatmary Peter
T Colonna Emily
T Enjuto Diego
T Montella (Azienda Unit\ue0 Sanitaria Locale-IRCCS di Reggio Emilia) Maria
TA Neely David
Tabiri Stephen
Tadross Daniel
Taglietti Lucio
Tansey (Princess Alexandra Hospital) Rosamond
Tartaglia Dario
Tawheed (Endemic Medicine Department Ahmed
Tayeh Salim
Testa Valentina
Tewari Nilanjana
Thoenissen Philipp
Thomas (Worcestershire Acute Hospitals NHS Trust) Kane
Thrush Jessica
Tierney Sean
Tiwari Abhinav
Tobias Teles (Hospital de Cascais - Dr. Jos\ue9 de Almeida) Pedro A Serralheiro
Toledo Enrique
Tonini Valeria
Torkington Jared
Torzilli Guido
Totty Joshua
Tousidonis Manuel
Townend Philip
Townsend Catherine
Trompeter (St George's Hospital) Alex
Trotta Francesco
Truant St\ue9phanie
Trujillo-D\uedaz Jeancarlos
Tsoulfas George
Tsoulfas Georgios
Turco Celia
Turkey: Volkan Ozben Georgios Peros (Kantonsspital Winterthur).
Turrado- Rodriguez Victor
Turri Giulia
Tustin (Cumberland Infirmary) Harry
Tyler Jayne
Tzedakis Stylianos
Tzovaras George
Ullah Ramzan
Unit\ue0 Sanitaria Locale di Ferrara Azienda
United Kingdom: Richard J Davies Alp Yildiz (Yildirim Beyazit University Yenimahalle Training and Research Hospital).
United States: John RT Monson (AdventHealth Orlando) Lavinia Onos (York Teaching Hospitals NHS Trust).
University Hospitals NHS Trust) Nottingham
University of Rome) Sapienza
University) Goethe
University) Helwan
Urban (University of Colorado Hospital) Shane
Urbani (Azienda Ospedaliero Universitaria San'Anna Alessia
Usai Antonella
V Bhavaraju Avi
V Comini Lara
V Feo Carlo
V Marino Marco
V Shaw Abigail
V\ue1zquez- Fern\ue1ndez Andrea
Vaccarella (Azienda Ospedaliera Gianpaolo
Valdes- Hernandez Javier
Valsecchi Luca
Vashisht Rajiv
VCO) Asl
Venkatesan (Glan Clwyd Hospital) Gowtham
Vera-Mansilla Cristina
Vergari (Ospedali Riuniti di Ancona) Roberto
Vescio (University 'Magna Graecia' of Catanzaro) Giuseppina
Vidya Raghavan
Vieira (Centro Hospital Universit\ue1rio S\ue3oJo\ue3o) Paula
Vijay Vardhini
Vimalachandran Dale
Vimalachandran Dale
Violante Tommaso
Vovola Fernanda
Vulliamy Paul
W Endorf (Hennepin Healthcare) Frederick
W Etchill Eric
W L\uf6ffler Markus
W L\uf6ffler Markus
Wall Rosemary
Wallwork Kate
Ward Alex
Warwick (University Hospital Southampton) David
Waseem Saima
Weaver Helen
Wells Fiona
Wen Jiaxin
West Raha
Whitehall Emma
Wild Laura
Wilkins Alex
Williams Gethin
Williams Matthew
Winnand (University Hospital Aachen) Philipp
Wong (Addenbrooke's Hospital) Ken
Worku (Queen\u2019s Medical Centre Dawit
Wright Naomi
WS Ho (Leeds Teaching Hospitals NHS Trust Michael
WT Ngu Albert
y Cajal) Cristina Cerro (Hospital Universitario Ram\uf3n
Y Oo (Department of Cardiothoracic Surgery Aung
y Polit\ue9cnico La Fe) Blas Flor (Hospital Universitario
Y van der Plas Willemijn
Yalamanchili Seema
Yershov (South Warwickshire NHS Foundation Trust) Danylo
Young Richard
Yousra Ahmed (Portsmouth Hospital NHS Trust) Simon Toh
Yurttas Can
Zadegan Frederic
Zafar (Northwick Park Hospital) Noman
Zakaria Rasheed
Zambon Martina
Zanini Nicola
ZE Durst Alexander
Zerbib Philippe
Zonta (Ospedale San Biagio Sandro
Publication venue: 'Elsevier BV'
Publication date: 01/01/2020
Field of study

Background: The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on postoperative recovery needs to be understood to inform clinical decision making during and after the COVID-19 pandemic. This study reports 30-day mortality and pulmonary complication rates in patients with perioperative SARS-CoV-2 infection. Methods: This international, multicentre, cohort study at 235 hospitals in 24 countries included all patients undergoing surgery who had SARS-CoV-2 infection confirmed within 7 days before or 30 days after surgery. The primary outcome measure was 30-day postoperative mortality and was assessed in all enrolled patients. The main secondary outcome measure was pulmonary complications, defined as pneumonia, acute respiratory distress syndrome, or unexpected postoperative ventilation. Findings: This analysis includes 1128 patients who had surgery between Jan 1 and March 31, 2020, of whom 835 (74·0%) had emergency surgery and 280 (24·8%) had elective surgery. SARS-CoV-2 infection was confirmed preoperatively in 294 (26·1%) patients. 30-day mortality was 23·8% (268 of 1128). Pulmonary complications occurred in 577 (51·2%) of 1128 patients; 30-day mortality in these patients was 38·0% (219 of 577), accounting for 81·7% (219 of 268) of all deaths. In adjusted analyses, 30-day mortality was associated with male sex (odds ratio 1·75 [95% CI 1·28–2·40], p\textless0·0001), age 70 years or older versus younger than 70 years (2·30 [1·65–3·22], p\textless0·0001), American Society of Anesthesiologists grades 3–5 versus grades 1–2 (2·35 [1·57–3·53], p\textless0·0001), malignant versus benign or obstetric diagnosis (1·55 [1·01–2·39], p=0·046), emergency versus elective surgery (1·67 [1·06–2·63], p=0·026), and major versus minor surgery (1·52 [1·01–2·31], p=0·047). Interpretation: Postoperative pulmonary complications occur in half of patients with perioperative SARS-CoV-2 infection and are associated with high mortality. Thresholds for surgery during the COVID-19 pandemic should be higher than during normal practice, particularly in men aged 70 years and older. Consideration should be given for postponing non-urgent procedures and promoting non-operative treatment to delay or avoid the need for surgery. Funding: National Institute for Health Research (NIHR), Association of Coloproctology of Great Britain and Ireland, Bowel and Cancer Research, Bowel Disease Research Foundation, Association of Upper Gastrointestinal Surgeons, British Association of Surgical Oncology, British Gynaecological Cancer Society, European Society of Coloproctology, NIHR Academy, Sarcoma UK, Vascular Society for Great Britain and Ireland, and Yorkshire Cancer Research

University of Liverpool Repository

Archivio istituzionale della ricerca - Università dell'Insubria

Catalogo dei prodotti della ricerca

Archivio istituzionale della ricerca - Università di Cagliari

Archivio istituzionale della ricerca - Università di Genova

White Rose Research Online

Archivio Istituzionale della Ricerca- Università del Piemonte Orientale

Archivio istituzionale della ricerca - Università di Palermo

Revista Científica Estudiantil - UNIMED

AIR Universita degli studi di Milano

UCrea

Ghent University Academic Bibliography

Archivsystem Ask23

Archivio istituzionale della ricerca - Alma Mater Studiorum Università di Bologna

University of Melbourne Institutional Repository

Explore Bristol Research

PubliCatt

University of Birmingham Research Portal

Spiral - Imperial College Digital Repository

Queen Mary Research Online

Archivio Istituzionale della Ricerca - Università degli Studi della Campania "Luigi Vanvitelli"

Archivio della Ricerca - Università di Pisa

UCL Discovery

Archivio della ricerca- Università di Roma La Sapienza

University of East Anglia digital repository

St George's Online Research Archive

A first update on mapping the human genetic architecture of COVID-19

Author: Abd Elghafar Mohamed S.
Abdel-Aziz Mahmoud
Abdollahi Hamed
Abdullah Tala
Abecasis Goncalo R.
Abedalthagafi Malak
Abul-Husn Noura S.
Acquilini Donatella
Adams Emma L.
Adamsara Alireza
Adeleye Olumide
Adra Darin
Afilalo Jonathan
Afilalo Marc
Afrasiabi Zaman
Agüero Daiana
Ahmadi Saeideh
Akhtar Shaheen
Aksentijevich Alexandra
Al-Afghani Hani
Al-Awdah Laila
Alaamery Manal
Alahmadey Ziab Z.
Alaverdian Diana
Alavere Helene
Albader Anoud
Albaiceta Guillermo M.
Albakri Jehad K.
AlBardis Hadeel
Albeladi Maha
Albesher Nour
Albrich W. C.
Albrich Werner
AlDhawi Nouf
Aleagha Afshar Etemadi
Alghamdi Bader
Alghamdi Jahad
Ali Altaf
Aliannejad Rasoul
Aljawini Nora
AlJohani Sameera
Alkwai Sarah
Allos Raili
AlMalik Abdulaziz
Almalki Faisal
Almohammed Iman
Almutairi Mansour
Alotaibi Sara
Alowayn Albandary M.
Alqahtani Saleh
Alqubaishi Fatimah
Alrashed May
Alshareef Abdulraheem
Alsolm Ebtehal
Alswailm Moneera
AlZahrani Deema
Amirsavadkouhi Ali
Amitrano Sara
Andolfo Immacolata
Andretta Francesca
Andreucci Elena
Andrews Shea J.
Anedda Federico
Anemoli Valentina
Angelantonio Emanuele Di
Annis Aubrey
Antinori Andrea
Antoni Melania Degli
Anwar Mohammad
Arabi Yaseen M.
Arciero Elena
Armstrong Jacob
Arning Nicolas
Arranz Maria J.
Arribas Elisa
Artuso Rosangela
Arumugam Prabhu
Ascolillo Steven
Ashraf Samina
Atkinson Elizabeth G.
Aucella Filippo
Auld Daniel
AZARZAR Samira
Bachetti Tiziana
Baillie J. Kenneth
Balaconis Mary K.
Baldassarri Margherita
Ball Catherine A.
Baltzell Asher Haug
Band Gavin
Bandini Maria
Baraka Dona
Baras Aris
Baratti Stefano
Barbieri Chiara
Barda B.
Bargagli Elena
Barhoush Eman
Barnes Kathleen C.
Baroni Silvia
Bartels Meike
Bassetti Matteo
Batini Chiara
Baya Nikolas
Beck Andrew
Beckmann Noam D.
Bedini Josep L.
Bee Catherine E.
Beguin Yves
Belbin Gillian M.
Belhaj Yasmine
Beligni Giada
Belisle Alexandre
Belli Mary Ann
Below Jennifer
Benetti Elisa
Bennett David
Bergantini Laura
Bergomi Paola
Berkowitz Nathan
Bernardo David
Biagio Antonio Di
Bianchi Francesco
Bibert Stéphanie
Bibert Stéphanie
Biesecker Les
Biscarini Filippo
Blay Natalia
Bochud M.
Bochud P. Y.
Bochud P. Y.
Bochud Pierre-Yves
Bochud Pierre-Yves
Boezen Marike
Boillat Noémie
Boillat-Blanco N.
Bottà Giordano
Bouab Meriem
Boughton Andrew P.
Bouras K.
Bradford Yuki
Brahier T.
Brassard Nathalie
Breen Gerome
Brenner Bluma
Britvan Bari
Brumpton Ben M.
Bruno Raffaele
Bruttini Mirella
Bryant Sam
Bryant Sam
Buring Julie E.
Busani Stefano
Bussotti Maurizio
Butler-Laporte Guillaume
Butterworth Adam S.
Buxbaum Joseph D.
Caldarelli Gian Piero
Callier Shawneequa
Cameli Paolo
Campbell Archie
Campbell Archie
Canaccini Anna
Cantarini Luca
Cantor Michael N.
Capasso Mario
Capitani Katia
Cappelli Silvia
Carella Massimo
Carey Dave J.
Carreras Anna
Carriero Miriam Lucia
Castaño-Vinyals Gemma
Castelli Francesco
Castori Marco
Catena Emanuele
Caulfield Mark J.
Ceri Stefano
Cerny A.
Chamnanphon Monpat
Chan Georgia
Chang Xiao
Chang Xiao
Chariyavilaskul Pajaree
Charney Alexander W.
Chasman Daniel I.
Chassot J.
Chassé Michaël
Chaudhary Kumardeep
Chavan Sameer
Chen Hung-Hsin
Cheng Nathan
Chetruengchai Wanna
Chittoor Geetha
Cho Judy H.
Cho Kelly
Choi Sam
Chowdhury Maharun
Chung Raymond
Churchhouse Claire
Chwialkowska Karolina
Claassen Sabine
Claringbould Annique
Clerc O.
Coignet Marie
Coiro Gabriella
Colligan Grainne
Collins Brett L.
Colobrán Roger
Colombo Riccardo
Conen A.
Conticini Edoardo
Cordioli Mattia
Cordioli Mattia
Corridi Marta
Cortés Beatriz
Cossarizza Andrea
Coto Eliecer
Coviello Domenico A.
Croci Leonardo
Croci Susanna
Crook Derrick W.
Crooks Kristy
Crotti Lia
Cullell Natalia
Curtis Charles J.
Cusick Caroline
Cárcel-Márquez Jara
Daga Sergio
Dalmau David
Daly Mark
Daly Mark J.
Danesh John
Darcis Gilles
Davis Lea
Daya Michelle
de Cid Rafael
de Felipe Mimbrera Alicia
de geus Eco E. J. C.
de la Cal-Sabater Paloma
DeDiego Marta L.
Deelen Patrick
Dei Simona
Deloukas Panos
Desanctis Elena
Desgranges F.
di Bartolomeo C.
Dietl Beatriz
Do Ron
Dobaño Carlota
Doddato Gabriella
Domenico Paolo Di
Domingo Carlos
Domínguez-Mayoral Anna
Donati Alice
Donner Kati
Durand Madeleine
Durham Ceri
D’Acremont V.
D’Alessandro Miriana
D’Arminio Monforte Antonella
D’Mellow Kenton
Earle Sarah G.
Egger T.
Eid Mohammed A.
El-Jawhari Jehan J.
El-Lawaty Walaa M.
El-shanshory Mohamed R.
El-Sherbiny Yasser M.
Elhadidy Tamer A.
Elnagdy Marwa H.
Eltoukhy Madonna M.
Emiliozzi Arianna
Emma Duncan
Erard Véronique
Erard Véronique
Esko Tõnu
Estoppey Younes S.
Fabbiani Massimiliano
Falcone Marco
Fallerini Chiara
Farré Xavier
Fava Francesca
Fawns-Ritchie Chloe
Fawns-Ritchie Chloe
fawzy Mohammad S.
Felemban Walaa A.
Feng Yen-Chen Anne
Feri Marco
Fernandez-Cadenas Israel
Ferreira Manuel A. R.
Ferri Claudio
Filipovic M.
Filippidis P.
Finer Sarah
Finer Sarah
Finucane Hilary
Fiorentino Giuseppe
Fiz-López Aida
Forgetta Vincenzo
Foucras S.
Fowler Tom
Franchi Federico
Francisci Daniela
Franco Giulianini
Franke Lude
Frediani Bruno
Free Robert C.
Frenckell Christian Von
Friolet R.
Frippiat Frédéric
Frischknecht M.
Frithiof Robert
Frullanti Elisa
Furini Simone
Gabbi Chiara
Gabrieli Arianna
Gaddis Michael
Galván-Femenía Iván
Ganna Andrea
Garcia-Aymerich Judith
García-Clemente Marta
García-Madrona Sebastian
Gass Matthew C.
Gatti Francesca
Gaziano J. Michael
Georges Michel
Gettler Kyle
Ghosh Biswarup
Giannattasio Ferdinando
Gignoux Christopher R.
Giliberti Annarita
Giorli Alessia
Giot Jean-Baptiste
Girardis Massimo
Girshick Ahna
Glessner Joseph R.
Glessner Joseph T.
Gofflot Stéphanie
Goldstein Jacqueline I.
Gomez Juan
Gonseth Nussle S.
González-Villa Esther
Gori Marco
Grassi Davide
Green Robert C.
Griffiths Chris
Griffiths Christopher J.
Grip Jonathan
Guarnaccia Alessandra
Guerrini Susanna
Guidelli Luca
Guillet A.
Guindo-Martinez Marta
Guiot Julien
Guntz Julien
Gupta Rahul
Guturu Harendra
Guyat-Jacques C.
Guyatt Anna L.
Guzman Charlotte
Guéry B.
Haefliger D.
Hakonarson Hakon
Hakonarson Hakon
Halawani Roaa T.
Harerimana Nadia
Harris Jennifer R.
Harthi Fawz Al
Hasanato Rana
Hayward Caroline
Hayward Caroline
Hegazy Mohamed A. F.
Helgeland Øyvind
Henry Danielle
Hensen Kati
Hiester Liam L.
Hirankarn Nattiya
Ho Yuk-Lam
Hoggart Clive
Hollox Edward J.
Hong Eurie L.
Horowitz Julie E.
Hosseini Abdolmajid
Hottenga Jouke Jan
Huang Qin Qin
Huang Qin Qin
Huckins Laura M.
Huffman Jennifer E.
Hultström Michael
Hunt Karen A.
Hunt Karen A.
Hurles Matt
Hussain Shapna
Huynen Pascale
Hveem Kristian
Hügli O.
Iglesias Lara Lloret
Ikram M. Arfan
Iolascon Achille
Islam Kamrul
Itan Yuval
Jacques Jessica
Jantarabenjakul Watsamon
Jaquet M.
Jiménez-Xarrié Elena
John Catherine
Jordan Daniel M.
Josyula Navya Shilpa
Jung Junghyun
Justice Anne E.
Kahlert C. R.
Kallaste Anne
Kamdar Dhryata
Kamdar Dhryata
Kampouri E. E.
Kanai Masahiro
Kanai Masahiro
Karczewski Konrad J.
Karjalainen Juha
Karlson Elizabeth W.
Karp Avromie
Kaufmann Daniel E.
Kaunisto Mari
Keller Katherine
Kenny Eimear E.
Kerchberger V. Eric
Kerr Shona M.
Khafaga Walid T.
Khan Ahsan
Khan Amara
Khattab Amin K.
Kimchi Nofar
King Daniel
Kisand Kai
Kivinen Katja
Kleger G-R.
Knapp C.
Knight Spencer
Koelling Nils
Kogevinas Manolis
Koskelainen Sami
Kosmicki Jack A.
Kousathanas Athanasios
Kristiansson Kati
Laane Edward
Labkowsky Alexander
Laisk Triin
Lambermont Bernard
Lannepoudenx Y.
Lanting Pauline
Lathrop G. Mark
Lauren Petty E.
Laurent Laetitia
Lavery Cath
Leader Joseph B.
Lee Paul H.
Lee Sang Hyuck
Lee Sulggi
Lee Yunsung
LeFaive Jonathon
Lena Fabio
Lepage Pierre
Lepamets Maarja
Lerner Robin
Levy Tess
Li Binglan
Li Kevin W.
Li Rui
Liao Rachel G.
Lin Shang-Kuan
Lipcsey Miklos
Lista Mirjam
Llucià-Carol Laia
Loos Ruth J. F.
Lopera Esteban
Lorubbio Maria
Lozano Francisco
Lu Wenhan
Lucas Anastasia
Luchi Sauro
Ludovisi Serena
Läll Kristi
Léonard Philippe
MacArthur Daniel
MacLaughlin Bev
Maggiolo Franco
Magnus Per
Mahmoud Ebrahim S.
Malaise Olivier
Mamlouk Noor
Mancarella Sandro
Mandalà Marco
Mangino Massimo
Mangul Serghei
Manson JoAnn E.
Mantovani Stefania
Manuel O.
Marcantonio Simona
MARCHETTI Oreste
Marciano Carmen
Mari Francesca
Maricic Tomislav
Martin Alicia R.
Martin Hilary
Martin Hilary C.
Martinelli Enrico
Martí-Fàbregas Joan
Martín-Nalda Andrea
Martínez Alba Parra
Masjuan Jaime
Mason Dan
Mason Dan
Massadeh Salam
Masucci Luca
Mazzei Maria Antonietta
McCormick Joseph B.
McCurdy Shannon
Medina-Gomez Carolina
Meigs James B.
Meloni Ilaria
Menatti Elisabetta
Mencarelli Maria Antonietta
Menéndez-Valladares Paloma
Mercader Josep
Mercader Josep Maria
Merla Giuseppe
Metsalu Kristjan
Metspalu Andres
Meuris Christelle
Meuwly J. Y.
Miah Shefa
Milani Lili
Miraglia Federica Gaia
Mirshahi Tooraj
Misset Benoît
Moahmed Hanteera S.
Moghaddam Seyed Behrooz Mohseni
Mohamed Attia A. S.
Mondelli Mario Umberto
Monica Matteo Della
Montagnani Francesca
Montillier P.
Mooser Vincent
Moreno Victor
Morris Marcela
Morrison David R.
Moutschen Michel
Moutsianas Loukas
Muiño Elena
Munting A.
Murphy Shawn N.
Mussini Cristina
Mutairi Amal Al
Márquez Leonardo
Mägi Reedik
Naaber Paul
Naderpour Zeinab
Nadkarni Girish N.
Nakanishi Tomoko
Neale Benjamin M.
Neale Benjamin M.
Negro T. Rochat
Nencioni Cesira
Neofytos Dionysios
Neofytos Dionysios
Newman Bill
Nguyen Huy
Niavarani Ahmadreza
Niblo Kristi
Niemi Mari E. K.
Nilaratanakul Voraphoj
Nivard Michel M. G.
Nkambul Lindo
Nkambul Lindokuhle
Nkambule Lindokuhle
Nkambule Lindokuhle
North Kari
Noto Keith
Nussle Semira Gonseth
Oddo M.
Odhams Christopher A.
Ognibene Agostino
Okasha Kamal
Oliveira Maureen
Ori Anil P. S.
O’Connell Anne Marie
O’Donnell Christopher J.
O’Mahony L.
O’Reilly Paul
Paciosi Francesco
Packer Richard J.
Pagani J. L.
Pagani J. L.
Palmer Duncan S.
Palmieri Maria
Palotie Aarno
Palotie Aarno
Pancrazzi Alessandro
Panese Sandro
Pantet O.
Papadimitriou-Olivgeris M.
Parati Gianfranco
Parisi Saverio Giuseppe
Park Danny
Parravicini Pierpaolo
Partha Raghavendran
Pasko Dorota
Pathak Gita A.
Pavlovic Milos
Peloso Gina
Perez Emma F.
Perez-Tur Jordi
Perna Rita
Perola Markus
Perrella Antonio
Perret A.
Peruggia Michael
Pessina Gloria
Pesukova Jaana
Peterson Pärt
Petitjean Louis
Petrocelli Paola
Phokaew Chureerat
Piacentini Paolo
Picchiotti Nicola
Pietro Massimo Di
Pigazzini Sara
Pinoli Pietro
Pinto Anna Maria
Pirinen Matti
Piscopo Carmelo
Planas Anna M.
Polikowski Hannah
Polimanti Renato
Polymeropoulos Christos
Polymeropoulos Mihael H.
Polymeropoulos Vasilios
Pongpanich Monnat
Porteous David J.
Porteous David J.
Portopena L.
Poscente Monica
Preuss Michael
Priest James
Przychodzen Bartlomiej P.
Pugin J.
Putchareon Opass
Puthanakit Thanyawee
Puusepp Mairo
Quinodoz Mathieu
Quinodoz Mathieu
Quiros-Roldan Eugenia
Rader Daniel
Rafaels Nicholas
Raggi Pamela
Ragoussis Jiannis
Rahmouni Souad
Raimondi Francesco
Rancan Ilaria
Rand Kristin
Ravaglia Sabrina
Regina J.
Reimann Ene
Rendon Augusto
Renieri Alessandra
Rezk Nardin
Rhead Brooke
Rhodes Daniel
Richards J. Brent
Richmond Anne
Richmond Anne
Rico Veronica
Ridker Paul M.
Rime M.
Ringmets Inge
Ripamonti Diego
Ripatti Samuli
Ritchie Marylyn D.
Riva Agostino
Rivolta Carlo
Rivolta Carlo
Rizzi Marco
Rizzo Caterina Lo
Roberts Genevieve
Robles Veronica
Rochat-Stettler L.
Rogne Tormod
Rojo Silvia
Romani Davide
Rooyackers Olav
Rossetti Barbara
Rovere Maria Teresa La
Rudkin Justine K.
Ruiz Luong
Ruiz-Jaén Francisca
Ruotsalainen Sanni
Rusconi Stefano
Russo Roberta
Sabrina Ravaglia
Saeedi Morteza
Safa Nishat
Safieh Leen Abu
Salerni Lorenzo
Salib Irene
Samir Amr
Sanarico Maurizio
Sanguinetti Maurizio
Sankaran Vijay G.
Sarma Gopal
Sarno Laura Di
Sarzi-Braga Simona
Satterstrom F. Kyle
Sauvage Anne-Sophie
Sawaji Mona
Scaggiante Renzo
Scala Raffaele
Schadt Eric E.
Schiaroli Elisabetta
Schurr Erwin
Scolletta Sabino
Scott Richard H.
Scotton Pier Giorgio
Sealfon Stuart C.
Sebra Robert P.
Seed Cotton
Segala Francesco Vladimiro
Segura Tomás
Serra-Llovich Alex
Serrano-Heras Gemma
Sesso Howard D.
Shahin Doaa
Sharififard Bahareh
Shaw Douglas M.
Shortt Jonathan
Shotelersuk Vorasuk
Shrine Nick
Siano Matteo
Sloofman Laura G.
Smieszek Sandra P.
Smith Albert V.
Smoller Jordan W.
Sobh Ali
Sodsai Pimpayao
Soler Pere
Solligard Erik
Solomonson Matthew
Solomonson Matthew
Soranzo Nicole
Soriano Alex
Spargi Genni
Spector Tim D.
Spencer Chris C. A.
Spertilli Chiara
Squeo Gabriella Maria
Starkopf Joel
Stella Alessandra
Stevens Christine
Stuckey Alex
Suardi Claudia
Suchartlikitwong Pintip
Suh N.
Suh Noémie
Suliman Bandar A.
Sumoy Lauro
Sun Yan V.
Suttels V.
Suttichet Thitima B.
Tabri Jekaterina
Tacconi Danilo
Tadi Hengameh Ansari
Tadini E.
Tahmasebi Farah
Tamm Anu
Tanfoni Marco
Tang Lara
Tardif Nicolas
Tavecchia Luisa
Tenesa Albert
Thompson Ryan C.
THYS Marie
Timmers Paul R. H. J.
Tiseo Giusy
Tita Rossella
Tobin Martin D.
Tommasi Andrea
Torky Mohamed S.
Torrents David
Torvorapanit Pattama
Trankiem Amy
Trembath Richard C.
Trembath Richard C.
Trivedi Bhavi
Trivedi Bhavi
Trogstad Lill-Iren S.
Trotta Tullio
Tsao Phil
Tschopp J.
Tselios Chris
Tsuo Kristin
Tumbarello Mario
Turley Patrick
Uitterlinden Andre G.
Underwood Slayton J.
Vaghi Massimo
Valente Serafina
Valentino Floriana
van Blokland Irene
van Heel David
van Heel David A.
van Heel David A.
Van Singer M.
Vecchia Marco
Veerapen Kumar
Venn Laura D.
Venturelli Sophie
Vergori Alessandra
Verma Anurag
Verma Shefali S.
Verzuri Agnese
Viala B.
Villalonga Joan Montaner
Vincenti Antonella
Viollet R. Merlet
Vivo Oreste De
Voide Cathy
Voide Cathy
Vollenweider P.
Vollenweider P.
von Hohenstaufen Kathrin Aprile
von Mering C.
Vonk Judith. M.
Vulesevic Branka
Wain Louise V.
Walker Susan
Walters Raymond K.
Wang Jiongming
Wang Xueyang
Wanying Zhu
Warmerdam Robert
Weiss Scott T.
Wicks Stephen J.
Willer Cristen
Williams Alexander T.
Wilson Daniel J.
Wilson James F.
Wolford Brooke
Wolford Brooke
Wolford Brooke
Woolley Ann E.
Wozniak H.
Wright John
Wright John
Wyllie David H.
Xue Xiaoqing
Yadav Ashish
Yassen Amr M.
Zanella Isabella
Zeberg Hugo
Zguro Kristina
Zhang Miao
Zhao Jing Hua
Zhou Wei
Zhou Wei
Zlatopolsky Menachem
zu Bentrup F. Meyer
Zucchi Patrizia
Zyndorf Marissa
Zöllner Sebastian
Åsvold Bjørn Olav
Publication venue: 'Springer Science and Business Media LLC'
Publication date: 01/01/2022
Field of study

peer reviewe

Archivio della ricerca - Università degli studi di Napoli Federico II

Archivio istituzionale della ricerca - Alma Mater Studiorum Università di Bologna

Open Repository and Bibliography - Liège

A quantitative chloride channel conductance assay for efficacy testing of AAV.BEST1

Author: Barnard Alun R.
MacLaren Robert E
Manson Forbes
Martinez-Fernandez de la Camara Cristina
McClements Michelle E.
Patricio Maria M
Sekaran Sumathi
Uggenti Carolina
Wood Shaun
Publication venue: 'Mary Ann Liebert Inc'
Publication date: 01/01/2019
Field of study

The University of Manchester - Institutional Repository

Acrania-Anencephaly Associated with Hypospadias. Prenatal Ultrasound and MRI Diagnosis and Molecular Folate Metabolism Pathway Analysis

Author: Alessandro Ventura
Arkell R
Beinder E
Botto LD
Bryan J
Devesa R
Fang KH
Gabriele Tonni
Giovanni Centini
Hendricks SK
Hogdall C
Lee A
Lin SK
Manson JM
Marcus-Soekarman D
Maria Paola Bonasoni
Martinez-Frias ML
Morgan EA
Odeh M
Opitz JM
Paulozzi L
Pennington EC
Pierpaolo Pattacini
Pietro Cavalli
Sepulveda W
Sides D
Smith DP
Smulian JC
Stephens FD
Timor-Tritsch IE
Tonni G
van der Werrf JFA
Viñals F
Wilkins-Haug L
Publication venue: 'Informa UK Limited'
Publication date
Field of study

Crossref

Humoral and In Vivo Cellular Immunity against the Raw Insect-Derived Recombinant Leishmania infantum Antigens KMPII, TRYP, LACK, and papLe22 in Dogs from an Endemic Area

Author: Acedo Sanchez
Alhelí Rodríguez-Cortés
Baneth
Barderas
Berberich
Berberich
Berrahal
Borja-Cabrera
Borja-Cabrera
Caldas
Campos-Neto
Cardoso
Carrillo
Carson
Carvalho
Carvalho
de Carvalho
Dos-Santos
Felicitat Todolí
Fragaki
Francino
Fujiwara
Gomes
Gradoni
Gramiccia
Holzmuller
Jensen
Jordi Alberola
José M. Escribano
Kemp
Kennedy
Khalil
Khalil
Kost
Kublin
Kurkjian
Laia Solano-Gallego
Livak
Maalej
Maasho
Manson-Bahr
Maria del Carmen Núñez
Martinez-Moreno
Marty
Mauricio
Medin
Medin
Meller-Melloul
Molano
Moreno
Ordeix
Pere Morell
Perez-Filgueira
Perez-Martin
Pinelli
Pinheiro
Pollock
Rafael de Juan
Rafati
Ramos
Riera
Riera
Rodrigo Lasa
Rodriguez-Cortes
Rodriguez-Cortes
Rodriguez-Cortes
Silveira
Silvia Gómez-Sebastián
Solano-Gallego
Solano-Gallego
Solano-Gallego
Suffia
Todoli
Todoli
Vandepapeliere
Webb
Publication venue: The American Society of Tropical Medicine and Hygiene
Publication date: 01/01/2010
Field of study

Leishmania infantum causes visceral leishmaniasis, a severe zoonotic and systemic disease that is fatal if left untreated. Identification of the antigens involved in Leishmania-specific protective immune response is a research priority for the development of effective control measures. For this purpose, we evaluated, in 27 dogs from an enzootic zone, specific humoral and cellular immune response by delayed-type hypersensitivity (DTH) skin test both against total L. infantum antigen and the raw Trichoplusia ni insect-derived kinetoplastid membrane protein-11 (rKMPII), tryparedoxin peroxidase (rTRYP), Leishmania homologue of receptors for activated C kinase (rLACK), and 22-kDa potentially aggravating protein of Leishmania (rpapLe22) antigens from this parasite. rTRYP induced the highest number of positive DTH responses (55% of leishmanin skin test [LST]-positive dogs), showing that TRYP antigen is an important T cell immunogen, and it could be a promising vaccine candidate against this disease. When TRYP-DTH and KMPII-DTH tests were evaluated in parallel, 82% of LST-positive dogs were detected, suggesting that both antigens could be considered as components of a standardized DTH immunodiagnostic tool for dogs

Crossref

PubMed Central

Digital.CSIC

The European Society for Immunodeficiencies (ESID) Registry Working Definitions for the Clinical Diagnosis of Inborn Errors of Immunity

Author: Abinun Mario
Albert Michael
Buckland Matthew
Bustamante Jacinta
Cant Andrew
Casanova Jean-Laurent
Chapel Helen
Cohen Sarah Beaussant
de Saint Basile Genevieve
de Vries Esther
Dokal Inderjeet
Donadieu Jean
Durandy Anne
Edgar David
Ehl Stephan
Espanol Teresa
Etzioni Amos
Fischer Alain
Gaspar Bobby
Gasteiger Lukas M.
Gathmann Benjamin
Gatti Richard
Gennery Andrew
Grigoriadou Sofia
Grimbacher Bodo
Holland Steven
Janka Gritta
Kanariou Maria
Kindle Gerhard
Klein Christoph
Lachmann Helen
Lilic Desa
Mahlaoui Nizar
Manson Ania
Martinez Natalia
Meyts Isabelle
Moes Nicolette
Moshous Despina
Neven Benedicte
Ochs Hans
Picard Capucine
Quinti Isabella
Renner Ellen
Rieux-Laucat Frederic
Rusch Stephan
Scheible Raphael
Seger Reinhard
Seidel Markus G.
Soresina Annarosa
Stoppa-Lyonnet Dominique
Thon Vojtech
Thrasher Adrian
van de Veerdonk Frank
van Montfrans Joris
Villa Anna
Warnatz Klaus
Weemaes Corry
Wolska Beata
Zhang Shen-Yin
Publication venue: 'Elsevier BV'
Publication date: 01/01/2019
Field of study

Patient registries are instrumental for clinical research in rare diseases. They help to achieve a sufficient sample size for epidemiological and clinical research and to assess the feasibility of clinical trials. The European Society for Immunodeficiencies (ESID) registry currently comprises information on more than 25,000 patients with inborn errors of immunity (IEI). The prerequisite of a patient to be included into the ESID registry is an IEI either defined by a defect in a gene included in the disease classification of the international union of immunological societies, or verified by applying clinical criteria. Because a relevant number of patients, including those with common variable immunodeficiency (CVID), representing the largest group of patients in the registry, remain without a genetic diagnosis, consensus on classification of these patients is mandatory. Here, we present clinical criteria for a large number of IEI that were designed in expert panels with an external review. They were implemented for novel entries and verification of existing data sets from 2014, yielding a substantial refinement. For instance, 8% of adults and 27% of children with CVID (176 of 1704 patients) were reclassified to 22 different immunodeficiencies, illustrating progress in genetics, but also the previous lack of standardized disease definitions. Importantly, apart from registry purposes, the clinical criteria are also helpful to support treatment decisions in the absence of a genetic diagnosis or in patients with variants of unknown significance

Archivio della ricerca- Università di Roma La Sapienza