39 research outputs found
The High-Metallicity Explosion Environment of the Relativistic Supernova 2009bb
We investigate the environment of the nearby (d ~ 40Mpc) broad-lined Type Ic
supernova SN 2009bb. This event was observed to produce a relativistic outflow
likely powered by a central accreting compact object. While such a phenomenon
was previously observed only in long-duration gamma-ray bursts (LGRBs), no LGRB
was detected in association with SN 2009bb. Using an optical spectrum of the SN
2009bb explosion site, we determine a variety of ISM properties for the host
environment, including metallicity, young stellar population age, and star
formation rate. We compare the SN explosion site properties to observations of
LGRB and broad-lined SN Ic host environments on optical emission line ratio
diagnostic diagrams. Based on these analyses, we find that the SN 2009bb
explosion site has a very high metallicity of ~2x solar, in agreement with
other broad-lined SN Ic host environments and at odds with the low-redshift
LGRB host environments and recently proposed maximum metallicity limits for
relativistic explosions. We consider the implications of these findings and the
impact that SN 2009bb's unusual explosive properties and environment have on
our understanding of the key physical ingredient that enables some SNe to
produce a relativistic outflow.Comment: 7 pages, 4 figures, 1 table; accepted for publication in ApJ Letters
(replaced to include missing figure
Post-Newtonian SPH calculations of binary neutron star coalescence. II. Binary mass ratio, equation of state, and spin dependence
Using our new Post-Newtonian SPH (smoothed particle hydrodynamics) code, we
study the final coalescence and merging of neutron star (NS) binaries. We vary
the stiffness of the equation of state (EOS) as well as the initial binary mass
ratio and stellar spins. Results are compared to those of Newtonian
calculations, with and without the inclusion of the gravitational radiation
reaction. We find a much steeper decrease in the gravity wave peak strain and
luminosity with decreasing mass ratio than would be predicted by simple
point-mass formulae. For NS with softer EOS (which we model as simple
polytropes) we find a stronger gravity wave emission, with a
different morphology than for stiffer EOS (modeled as polytropes as
in our previous work). We also calculate the coalescence of NS binaries with an
irrotational initial condition, and find that the gravity wave signal is
relatively suppressed compared to the synchronized case, but shows a very
significant second peak of emission. Mass shedding is also greatly reduced, and
occurs via a different mechanism than in the synchronized case. We discuss the
implications of our results for gravity wave astronomy with laser
interferometers such as LIGO, and for theoretical models of gamma-ray bursts
(GRBs) based on NS mergers.Comment: RevTeX, 38 pages, 24 figures, Minor Corrections, to appear in Phys.
Rev.
Maltreated children use more grammatical negations
Many studies reveal a strong impact of childhood maltreatment on language development, mainly resulting in shorter utterances, less rich vocabulary, or a delay in grammatical complexity. However, different theories suggest the possibility for resilience – a positive adaptation to an otherwise adverse environment – in children who experienced childhood maltreatment. Here, we investigated different measures for language development in spontaneous speech, examining whether childhood maltreatment leads to a language deficit only or whether it can also result in differences in language use due to a possible adaptation to a toxic environment. We compared spontaneous speech during therapeutic peer-play sessions of 32 maltreated and 32 non-maltreated children from the same preschool and equivalent in gender, age (2 to 5 years), home neighborhood, ethnicity, and family income. Maltreatment status was reported by formal child protection reports, and corroborated by independent social service reports. We investigated general language sophistication (i.e., vocabulary, talkativeness, mean length of utterance), as well as grammatical development (i.e., use of plurals, tense, grammatical negations). We found that maltreated and non-maltreated children showed similar sophistication across all linguistic measures, except for the use of grammatical negations. Maltreated children used twice as many grammatical negations as non-maltreated children. The use of this highly complex grammatical structure shows an advanced linguistic skill, which shows that childhood maltreatment does not necessarily lead to a language deficit. The result might indicate the development of a negativity bias in the structure of spontaneous language due to an adaptation to their experiences
The 999th Swift gamma-ray burst: Some like it thermal: A multiwavelength study of GRB 151027A
We present a multiwavelength study of GRB 151027A. This is the 999th GRB
detected by the Swift satellite and it has a densely sampled emission in the
X-ray and optical band and has been observed and detected in the radio up to
140 days after the prompt. The multiwavelength light curve from 500 s to 140
days can be modelled through a standard forward shock afterglow but requires an
additional component to reproduce the early X-ray and optical emission. We
present TNG and LBT optical observations performed 19.6, 33.9 and 92.3 days
after the trigger which show a bump with respect to a standard afterglow flux
decay and are possibly interpreted as due to the underlying SN and host galaxy
(of 0.4 uJy in the R band). Radio observations, performed with SRT, Medicina,
EVN and VLBA between day 4 and 140, suggest that the burst exploded in an
environment characterised by a density profile scaling with the distance from
the source (wind profile). A remarkable feature of the prompt emission is the
presence of a bright flare 100 s after the trigger, lasting 70 seconds in the
soft X-ray band, which was simultaneously detected from the optical band up to
the MeV energy range. By combining Swift-BAT/XRT and Fermi-GBM data, the
broadband (0.3-1000 keV) time resolved spectral analysis of the flare reveals
the coexistence of a non-thermal (power law) and thermal blackbody components.
The BB component contributes up to 35% of the luminosity in the 0.3-1000 keV
band. The gamma-ray emission observed in Swift-BAT and Fermi-GBM anticipates
and lasts less than the soft X-ray emission as observed by Swift-XRT, arguing
against a Comptonization origin. The BB component could either be produced by
an outflow becoming transparent or by the collision of a fast shell with a
slow, heavy and optically thick fireball ejected during the quiescent time
interval between the initial and later flares of the burst
Variation in Structure and Process of Care in Traumatic Brain Injury: Provider Profiles of European Neurotrauma Centers Participating in the CENTER-TBI Study.
INTRODUCTION: The strength of evidence underpinning care and treatment recommendations in traumatic brain injury (TBI) is low. Comparative effectiveness research (CER) has been proposed as a framework to provide evidence for optimal care for TBI patients. The first step in CER is to map the existing variation. The aim of current study is to quantify variation in general structural and process characteristics among centers participating in the Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) study. METHODS: We designed a set of 11 provider profiling questionnaires with 321 questions about various aspects of TBI care, chosen based on literature and expert opinion. After pilot testing, questionnaires were disseminated to 71 centers from 20 countries participating in the CENTER-TBI study. Reliability of questionnaires was estimated by calculating a concordance rate among 5% duplicate questions. RESULTS: All 71 centers completed the questionnaires. Median concordance rate among duplicate questions was 0.85. The majority of centers were academic hospitals (n = 65, 92%), designated as a level I trauma center (n = 48, 68%) and situated in an urban location (n = 70, 99%). The availability of facilities for neuro-trauma care varied across centers; e.g. 40 (57%) had a dedicated neuro-intensive care unit (ICU), 36 (51%) had an in-hospital rehabilitation unit and the organization of the ICU was closed in 64% (n = 45) of the centers. In addition, we found wide variation in processes of care, such as the ICU admission policy and intracranial pressure monitoring policy among centers. CONCLUSION: Even among high-volume, specialized neurotrauma centers there is substantial variation in structures and processes of TBI care. This variation provides an opportunity to study effectiveness of specific aspects of TBI care and to identify best practices with CER approaches
Variation in monitoring and treatment policies for intracranial hypertension in traumatic brain injury: A survey in 66 neurotrauma centers participating in the CENTER-TBI study
The distributions of species are not only determined by where they can survive – they must also be able to reproduce. Although immigrant inviability is a well-established concept, the fact that immigrants also need to be able to effectively reproduce in foreign environments has not been fully appreciated in the study of adaptive divergence and speciation. Fertilization and reproduction are sensitive life-history stages that could be detrimentally affected for immigrants in non-native habitats. We propose that “immigrant reproductive dysfunction” is a hitherto overlooked aspect of reproductive isolation caused by natural selection on immigrants. This idea is supported by results from experiments on an externally fertilizing fish (sand goby, Pomatoschistus minutus). Growth and condition of adults were not affected by non-native salinity whereas males spawning as immigrants had lower sperm motility and hatching success than residents. We interpret these results as evidence for local adaptation or acclimation of sperm, and possibly also components of paternal care. The resulting loss in fitness, which we call “immigrant reproductive dysfunction,” has the potential to reduce gene flow between populations with locally adapted reproduction, and it may play a role in species distributions and speciation.</p
Variation in structure and process of care in traumatic brain injury: Provider profiles of European Neurotrauma Centers participating in the CENTER-TBI study
Introduction: The strength of evidence underpinning care and treatment recommendations in traumatic brain injury (TBI) is low. Comparative effectiveness research (CER) has been proposed as a framework to provide evidence for optimal care for TBI patients. The first step in CER is to map the existing variation. The aim of current study is to quantify variation in general structural and process characteristics among centers participating in the Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) study. Methods: We designed a set of 11 provider profiling questionnaires with 321 questions about various aspects of TBI care, chosen based on literature and expert opinion. After pilot testing, questionnaires were disseminated to 71 centers from 20 countries participating in the CENTER-TBI study. Reliability of questionnaires was estimated by calculating a concordance rate among 5% duplicate questions.Results: All 71 centers completed the questionnaires. Median concordance rate among duplicate questions was 0.85. The majority of centers were academic hospitals (n = 65, 92%), designated as a level I trauma center (n = 48, 68%) and situated in an urban location (n = 70, 99%). The availability of facilities for neuro-trauma care varied across centers; e.g. 40 (57%) had a dedicated neuro-intensive care unit (ICU), 36 (51%) had an in-hospital rehabilitation unit and the organization of the ICU was closed in 64% (n = 45) of the centers. In addition, we found wide variation in processes of care, such as the ICU admission policy and intracranial pressure monitoring policy among centers. Conclusion: Even among high-volume, specialized neurotrauma centers there is substantial variation in structures and processes of TBI care. This variation provides an opportunity to study effectiveness of specific aspects of TBI care and to identify best practices with CER approaches.</p
Variation in monitoring and treatment policies for intracranial hypertension in traumatic brain injury: A survey in 66 neurotrauma centers participating in the CENTER-TBI
Background: No definitive evidence exists on how intracranial hypertension should be treated in patients with traumatic brain injury (TBI). It is therefore likely that centers and practitioners individually balance potential benefits and risks of different intracranial pressure (ICP) management strategies, resulting in practice variation. The aim of this study was to examine variation in monitoring and treatment policies for intracranial hypertension in patients with TBI.
Methods: A 29-item survey on ICP monitoring and treatment was developed based on literature and expert opinion, and pilot-tested in 16 centers. The questionnaire was sent to 68 neurotrauma centers participating in the Collaborative European Neurotrauma Effectiveness Research (CENTER-TBI) study.
Results: The survey was completed by 66 centers (97% response rate). Centers were mainly academic hospitals (n = 60, 91%) and designated level I trauma centers (n = 44, 67%). The Brain Trauma Foundation guidelines were used in 49 (74%) centers. Approximately ninety percent of the participants (n = 58) indicated placing an ICP monitor in patients with severe TBI and computed tomography abnormalities. There was no consensus on other indications or on peri-insertion precautions. We found wide variation in the use of first- and second-tier treatments for elevated ICP. Approximately half of the centers were classified as having a relatively aggressive approach to ICP monitoring and treatment (n = 32, 48%), whereas the others were considered more conservative (n = 34, 52%).
Conclusions: Substantial variation was found regarding monitoring and treatment policies in patients with traumatic brain injury and intracranial hypertension. The results of this survey indicate a lack of consensus between European neurotrauma centers and provide an opportunity and necessity for comparative effectiveness research
Variation in general supportive and preventive intensive care management of traumatic brain injury: a survey in 66 neurotrauma centers participating in the Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) study
Abstract
Background
General supportive and preventive measures in the intensive care management of traumatic brain injury (TBI) aim to prevent or limit secondary brain injury and optimize recovery. The aim of this survey was to assess and quantify variation in perceptions on intensive care unit (ICU) management of patients with TBI in European neurotrauma centers.
Methods
We performed a survey as part of the Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) study. We analyzed 23 questions focused on: 1) circulatory and respiratory management; 2) fever control; 3) use of corticosteroids; 4) nutrition and glucose management; and 5) seizure prophylaxis and treatment.
Results
The survey was completed predominantly by intensivists (n = 33, 50%) and neurosurgeons (n = 23, 35%) from 66 centers (97% response rate).
The most common cerebral perfusion pressure (CPP) target was > 60 mmHg (n = 39, 60%) and/or an individualized target (n = 25, 38%). To support CPP, crystalloid fluid loading (n = 60, 91%) was generally preferred over albumin (n = 15, 23%), and vasopressors (n = 63, 96%) over inotropes (n = 29, 44%). The most commonly reported target of partial pressure of carbon dioxide in arterial blood (PaCO2) was 36–40 mmHg (4.8–5.3 kPa) in case of controlled intracranial pressure (ICP) < 20 mmHg (n = 45, 69%) and PaCO2 target of 30–35 mmHg (4–4.7 kPa) in case of raised ICP (n = 40, 62%). Almost all respondents indicated to generally treat fever (n = 65, 98%) with paracetamol (n = 61, 92%) and/or external cooling (n = 49, 74%). Conventional glucose management (n = 43, 66%) was preferred over tight glycemic control (n = 18, 28%). More than half of the respondents indicated to aim for full caloric replacement within 7 days (n = 43, 66%) using enteral nutrition (n = 60, 92%). Indications for and duration of seizure prophylaxis varied, and levetiracetam was mostly reported as the agent of choice for both seizure prophylaxis (n = 32, 49%) and treatment (n = 40, 61%).
Conclusions
Practice preferences vary substantially regarding general supportive and preventive measures in TBI patients at ICUs of European neurotrauma centers. These results provide an opportunity for future comparative effectiveness research, since a more evidence-based uniformity in good practices in general ICU management could have a major impact on TBI outcome