DAMA/LIBRA-phase1 results and perspectives of the phase2

The results obtained with the total exposure of 1.04 ton × yr collected by DAMA/LIBRA–phase1 deep underground at the Gran Sasso National Laboratory (LNGS) of the I.N.F.N. during 7 annual cycles are summarized. The DAMA/LIBRA–phase1 and the former DAMA/NaI data (cumulative exposure 1.33 ton × yr, corresponding to 14 annual cycles) give evidence at 9.3 σ C.L. for the presence of Dark Matter (DM) particles in the galactic halo, on the basis of the exploited model independent DM annual modulation signature by using highly radio-pure NaI(Tl) target. No systematic or side reaction able to mimic the exploited DM signature has been found or suggested by anyone over more than a decade. The same data of DAMA/LIBRA–phase1 have also been analyzed searching for possible DM second-order diurnal effect; at present, the DM diurnal modulation amplitude – expected because of the Earth diurnal motion – evaluated on the basis of the DAMA Dark Matter annual modulation results is below the reached experimental sensitivity. Some of the perspectives of the presently running DAMA/LIBRA–phase2 are outlined

Highlights of DAMA/LIBRA

The DAMA project develops and uses new improved low background scintillation detectors to investigate the Dark Matter (DM) particle component(s) in the galactic halo and rare processes deep underground at the Gran Sasso National Laboratory (LNGS) of the I.N.F.N.. Here some highlights of DAMA/LIBRA (Large sodium Iodide Bulk for Rare processes) as a unique apparatus in direct DM investigation for its full sensitive mass, target material, intrinsic radio-purity, methodological approach and all the controls performed on the experimental parameters are outlined. The DAMA/LIBRA–phase1 and the former DAMA/NaI data (cumulative exposure 1.33 ton × yr, corresponding to 14 annual cycles)have reached a model-independent evidence at 9.3 σ C.L. for the presence of DM particles in the galactic halo exploiting the DM annual modulation signature with highly radio-pure NaI(Tl) target. Some of the perspectives of the presently running DAMA/LIBRA–phase2 are summarised and the powerful tools offered by a model independent strategy of DM investigation are pointed out

Numerical Computations with H(div)-Finite Elements for the Brinkman Problem

The H(div)-conforming approach for the Brinkman equation is studied numerically, verifying the theoretical a priori and a posteriori analysis in previous work of the authors. Furthermore, the results are extended to cover a non-constant permeability. A hybridization technique for the problem is presented, complete with a convergence analysis and numerical verification. Finally, the numerical convergence studies are complemented with numerical examples of applications to domain decomposition and adaptive mesh refinement.Comment: Minor clarifications, added references. Reordering of some figures. To appear in Computational Geosciences, final article available at http://www.springerlink.co

Further results from DAMA/LIBRA-phase2 and perspectives

The data collected by the DAMA/LIBRA-phase2 set-up during two additional annual cycles have been analyzed, further investigating the long-standing model-independent annual modulation effect pointed out by DAMA deep underground at the Gran Sasso National Laboratory of the I.N.F.N. by using various different experimental configurations. Including the new results, the total exposure of DAMA/LIBRA-phase2 over 8 annual cycles is 1.53 t·yr and the evidence for a signal that meets all the requirements of the model-independent Dark Matter annual modulation signature is 11.8 σ C.L. in the energy region (1 - 6) keV. In the (2 - 6) keV energy interval, where data are also available from DAMA/NaI and DAMA/LIBRA-phase1, the achieved C.L. for the full exposure of 2.86 t·yr is 13.7 σ. No systematics or side reaction able to mimic this signature (i.e., to account for the whole measured modulation amplitude and to simultaneously satisfy all the requirements of the signature) has been found or suggested by anyone throughout some decades thus far. A preliminary result on the further lowering of the software energy threshold and perspectives are also mentioned

New results from DAMA/LIBRA

DAMA/LIBRA is running at the Gran Sasso National Laboratory of the I.N.F.N.. Here the results obtained with a further exposure of 0.34 ton x yr are presented. They refer to two further annual cycles collected one before and one after the first DAMA/LIBRA upgrade occurred on September/October 2008. The cumulative exposure with those previously released by the former DAMA/NaI and by DAMA/LIBRA is now 1.17 ton x yr, corresponding to 13 annual cycles. The data further confirm the model independent evidence of the presence of Dark Matter (DM) particles in the galactic halo on the basis of the DM annual modulation signature (8.9 sigma C.L. for the cumulative exposure). In particular, with the cumulative exposure the modulation amplitude of the single-hit events in the (2 -- 6) keV energy interval measured in NaI(Tl) target is (0.0116 +- 0.0013) cpd/kg/keV; the measured phase is (146 +- 7) days and the measured period is (0.999 +- 0.002) yr, values well in agreement with those expected for the DM particles.Comment: presented at the Int. Conf. Beyond the Standard Models of Particle Physics, Cosmology and Astrophysics (BEYOND 2010), 1-6 February 2010, Cape Town, South Afric

Magnetic Reconnection in Extreme Astrophysical Environments

Magnetic reconnection is a basic plasma process of dramatic rearrangement of magnetic topology, often leading to a violent release of magnetic energy. It is important in magnetic fusion and in space and solar physics --- areas that have so far provided the context for most of reconnection research. Importantly, these environments consist just of electrons and ions and the dissipated energy always stays with the plasma. In contrast, in this paper I introduce a new direction of research, motivated by several important problems in high-energy astrophysics --- reconnection in high energy density (HED) radiative plasmas, where radiation pressure and radiative cooling become dominant factors in the pressure and energy balance. I identify the key processes distinguishing HED reconnection: special-relativistic effects; radiative effects (radiative cooling, radiation pressure, and Compton resistivity); and, at the most extreme end, QED effects, including pair creation. I then discuss the main astrophysical applications --- situations with magnetar-strength fields (exceeding the quantum critical field of about 4 x 10^13 G): giant SGR flares and magnetically-powered central engines and jets of GRBs. Here, magnetic energy density is so high that its dissipation heats the plasma to MeV temperatures. Electron-positron pairs are then copiously produced, making the reconnection layer highly collisional and dressing it in a thick pair coat that traps radiation. The pressure is dominated by radiation and pairs. Yet, radiation diffusion across the layer may be faster than the global Alfv\'en transit time; then, radiative cooling governs the thermodynamics and reconnection becomes a radiative transfer problem, greatly affected by the ultra-strong magnetic field. This overall picture is very different from our traditional picture of reconnection and thus represents a new frontier in reconnection research.Comment: Accepted to Space Science Reviews (special issue on magnetic reconnection). Article is based on an invited review talk at the Yosemite-2010 Workshop on Magnetic Reconnection (Yosemite NP, CA, USA; February 8-12, 2010). 30 pages, no figure

Planetary population synthesis

In stellar astrophysics, the technique of population synthesis has been successfully used for several decades. For planets, it is in contrast still a young method which only became important in recent years because of the rapid increase of the number of known extrasolar planets, and the associated growth of statistical observational constraints. With planetary population synthesis, the theory of planet formation and evolution can be put to the test against these constraints. In this review of planetary population synthesis, we first briefly list key observational constraints. Then, the work flow in the method and its two main components are presented, namely global end-to-end models that predict planetary system properties directly from protoplanetary disk properties and probability distributions for these initial conditions. An overview of various population synthesis models in the literature is given. The sub-models for the physical processes considered in global models are described: the evolution of the protoplanetary disk, the planets' accretion of solids and gas, orbital migration, and N-body interactions among concurrently growing protoplanets. Next, typical population synthesis results are illustrated in the form of new syntheses obtained with the latest generation of the Bern model. Planetary formation tracks, the distribution of planets in the mass-distance and radius-distance plane, the planetary mass function, and the distributions of planetary radii, semimajor axes, and luminosities are shown, linked to underlying physical processes, and compared with their observational counterparts. We finish by highlighting the most important predictions made by population synthesis models and discuss the lessons learned from these predictions - both those later observationally confirmed and those rejected.Comment: 47 pages, 12 figures. Invited review accepted for publication in the 'Handbook of Exoplanets', planet formation section, section editor: Ralph Pudritz, Springer reference works, Juan Antonio Belmonte and Hans Deeg, Ed

Evasion of anti-growth signaling: a key step in tumorigenesis and potential target for treatment and prophylaxis by natural compounds

The evasion of anti-growth signaling is an important characteristic of cancer cells. In order to continue to proliferate, cancer cells must somehow uncouple themselves from the many signals that exist to slow down cell growth. Here, we define the anti-growth signaling process, and review several important pathways involved in growth signaling: p53, phosphatase and tensin homolog (PTEN), retinoblastoma protein (Rb), Hippo, growth differentiation factor 15 (GDF15), AT-rich interactive domain 1A (ARID1A), Notch, insulin-like growth factor (IGF), and Krüppel-like factor 5 (KLF5) pathways. Aberrations in these processes in cancer cells involve mutations and thus the suppression of genes that prevent growth, as well as mutation and activation of genes involved in driving cell growth. Using these pathways as examples, we prioritize molecular targets that might be leveraged to promote anti-growth signaling in cancer cells. Interestingly, naturally-occurring phytochemicals found in human diets (either singly or as mixtures) may promote anti-growth signaling, and do so without the potentially adverse effects associated with synthetic chemicals. We review examples of naturally-occurring phytochemicals that may be applied to prevent cancer by antagonizing growth signaling, and propose one phytochemical for each pathway. These are: epigallocatechin-3-gallate (EGCG) for the Rb pathway, luteolin for p53, curcumin for PTEN, porphyrins for Hippo, genistein for GDF15, resveratrol for ARID1A, withaferin A for Notch and diguelin for the IGF1-receptor pathway. The coordination of anti-growth signaling and natural compound studies will provide insight into the future application of these compounds in the clinical setting