502 research outputs found
Developmental stages of myeloid dendritic cells in mouse bone marrow
The lineage relationship of dendritic cells (DC) with other hematopoietic
cell types has been studied extensively, resulting in the identification
of different bone marrow (BM) progenitors that give rise to distinct DC
types. However, the identity of the different maturation stages of DC
precursors in the BM remains unclear. In this study we define the in vivo
developmental steps of the myeloid DC lineage in mouse BM. To this end, BM
cells were separated according to their expression of CD31 (ER-MP12),
Ly-6C (ER-MP20) and ER-MP58 antigens, and stimulated to develop into
myeloid DC, using granulocyte macrophage colony stimulating factor as a
specific growth factor. DC developed from three BM subpopulations:
ER-MP12(hi)/20(-) (early blast cells), ER-MP12(+)/20(+) (myeloid blasts)
and ER-MP12(-)/20(hi) (monocytes). The kinetic and phenotypic features of
DC developing in vitro indicate that the three populations represent
successive maturation stages of myeloid DC precursors. Within the earliest
ER-MP12(hi)/20(-) population, DC precursors exclusively occurred in the
myeloid-restricted ER-MP58(hi) subset. By using switch cultures, we show
that these BM precursor subpopulations, when stimulated to develop into
macrophages using macrophage colony stimulating factor, retain the ability
to develop into myeloid DC until advanced stages of maturation. Together,
these findings support a common ER-MP12/20-defined differentiation pathway
for both macrophages and myeloid DC throughout their BM development
Negative Kaons in Dense Baryonic Matter
Kaon polarization operator in dense baryonic matter of arbitrary isotopic
composition is calculated including s- and p-wave kaon-baryon interactions. The
regular part of the polarization operator is extracted from the realistic
kaon-nucleon interaction based on the chiral and 1/N_c expansion. Contributions
of the Lambda(1116), Sigma(1195), Sigma*(1385) resonances are taken explicitly
into account in the pole and regular terms with inclusion of mean-field
potentials. The baryon-baryon correlations are incorporated and fluctuation
contributions are estimated. Results are applied for K- in neutron star matter.
Within our model a second-order phase transition to the s-wave K- condensate
state occurs at rho_c \gsim 4 \rho_0 once the baryon-baryon correlations are
included. We show that the second-order phase transition to the p-wave
condensate state may occur at densities in
dependence on the parameter choice. We demonstrate that a first-order phase
transition to a proton-enriched (approximately isospin-symmetric) nucleon
matter with a p-wave K- condensate can occur at smaller densities, \rho\lsim 2
\rho_0. The transition is accompanied by the suppression of hyperon
concentrations.Comment: 41 pages, 24 figures, revtex4 styl
The open-charm radiative and pionic decays of molecular charmonium Y(4274)
In this work, we investigate the decay widths and the line shapes of the
open-charm radiative and pionic decays of Y(4274) with the
molecular charmonium assignment. Our calculation
indicates that the decay widths of and
can reach up to 0.05 keV and 0.75 keV,
respectively. In addition, the result of the line shape of the photon spectrum
of shows that there exists a very sharp
peak near the large end point of photon energy. The line shape of the pion
spectrum of is similar to that of the pion
spectrum of , where we also find a very
sharp peak near the large end point of pion energy. According to our
calculation, we suggest further experiments to carry out the search for the
open-charm radiative and pionic decays of Y(4274).Comment: 7 pages, 6 figures, 1 table. Published versio
Chiral dynamics of p-wave in K^- p and coupled states
We perform an evaluation of the p-wave amplitudes of meson-baryon scattering
in the strangeness S=-1 sector starting from the lowest order chiral
Lagrangians and introducing explicitly the Sigma^* field with couplings to the
meson-baryon states obtained using SU(6) symmetry. The N/D method of
unitarization is used, equivalent, in practice, to the use of the
Bethe-Salpeter equation with a cut-off. The procedure leaves no freedom for the
p-waves once the s-waves are fixed and thus one obtains genuine predictions for
the p-wave scattering amplitudes, which are in good agreement with experimental
results for differential cross sections, as well as for the width and partial
decay widths of the Sigma^*(1385).Comment: LaTeX, 18 pages, 6 figure
Light meson mass dependence of the positive parity heavy-strange mesons
We calculate the masses of the resonances D_{s0}^*(2317) and D_{s1}(2460) as
well as their bottom partners as bound states of a kaon and a D^*- and
B^*-meson, respectively, in unitarized chiral perturbation theory at
next-to-leading order. After fixing the parameters in the D_{s0}^*(2317)
channel, the calculated mass for the D_{s1}(2460) is found in excellent
agreement with experiment. The masses for the analogous states with a bottom
quark are predicted to be M_{B^*_{s0}}=(5696\pm 40) MeV and M_{B_{s1}}=(5742\pm
40) MeV in reasonable agreement with previous analyses. In particular, we
predict M_{B_{s1}}-M_{B_{s0}^*}=46\pm 1 MeV. We also explore the dependence of
the states on the pion and kaon masses. We argue that the kaon mass dependence
of a kaonic bound state should be almost linear with slope about unity. Such a
dependence is specific to the assumed molecular nature of the states. We
suggest to extract the kaon mass dependence of these states from lattice QCD
calculations.Comment: 10 page
Global shifts, theoretical shifts: changing geographies of religion
10.1177/0309132510362602Progress in Human Geography346755-77
Search for a W' boson decaying to a bottom quark and a top quark in pp collisions at sqrt(s) = 7 TeV
Results are presented from a search for a W' boson using a dataset
corresponding to 5.0 inverse femtobarns of integrated luminosity collected
during 2011 by the CMS experiment at the LHC in pp collisions at sqrt(s)=7 TeV.
The W' boson is modeled as a heavy W boson, but different scenarios for the
couplings to fermions are considered, involving both left-handed and
right-handed chiral projections of the fermions, as well as an arbitrary
mixture of the two. The search is performed in the decay channel W' to t b,
leading to a final state signature with a single lepton (e, mu), missing
transverse energy, and jets, at least one of which is tagged as a b-jet. A W'
boson that couples to fermions with the same coupling constant as the W, but to
the right-handed rather than left-handed chiral projections, is excluded for
masses below 1.85 TeV at the 95% confidence level. For the first time using LHC
data, constraints on the W' gauge coupling for a set of left- and right-handed
coupling combinations have been placed. These results represent a significant
improvement over previously published limits.Comment: Submitted to Physics Letters B. Replaced with version publishe
Search for the standard model Higgs boson decaying into two photons in pp collisions at sqrt(s)=7 TeV
A search for a Higgs boson decaying into two photons is described. The
analysis is performed using a dataset recorded by the CMS experiment at the LHC
from pp collisions at a centre-of-mass energy of 7 TeV, which corresponds to an
integrated luminosity of 4.8 inverse femtobarns. Limits are set on the cross
section of the standard model Higgs boson decaying to two photons. The expected
exclusion limit at 95% confidence level is between 1.4 and 2.4 times the
standard model cross section in the mass range between 110 and 150 GeV. The
analysis of the data excludes, at 95% confidence level, the standard model
Higgs boson decaying into two photons in the mass range 128 to 132 GeV. The
largest excess of events above the expected standard model background is
observed for a Higgs boson mass hypothesis of 124 GeV with a local significance
of 3.1 sigma. The global significance of observing an excess with a local
significance greater than 3.1 sigma anywhere in the search range 110-150 GeV is
estimated to be 1.8 sigma. More data are required to ascertain the origin of
this excess.Comment: Submitted to Physics Letters
Measurement of the Lambda(b) cross section and the anti-Lambda(b) to Lambda(b) ratio with Lambda(b) to J/Psi Lambda decays in pp collisions at sqrt(s) = 7 TeV
The Lambda(b) differential production cross section and the cross section
ratio anti-Lambda(b)/Lambda(b) are measured as functions of transverse momentum
pt(Lambda(b)) and rapidity abs(y(Lambda(b))) in pp collisions at sqrt(s) = 7
TeV using data collected by the CMS experiment at the LHC. The measurements are
based on Lambda(b) decays reconstructed in the exclusive final state J/Psi
Lambda, with the subsequent decays J/Psi to an opposite-sign muon pair and
Lambda to proton pion, using a data sample corresponding to an integrated
luminosity of 1.9 inverse femtobarns. The product of the cross section times
the branching ratio for Lambda(b) to J/Psi Lambda versus pt(Lambda(b)) falls
faster than that of b mesons. The measured value of the cross section times the
branching ratio for pt(Lambda(b)) > 10 GeV and abs(y(Lambda(b))) < 2.0 is 1.06
+/- 0.06 +/- 0.12 nb, and the integrated cross section ratio for
anti-Lambda(b)/Lambda(b) is 1.02 +/- 0.07 +/- 0.09, where the uncertainties are
statistical and systematic, respectively.Comment: Submitted to Physics Letters
Search for new physics in events with opposite-sign leptons, jets, and missing transverse energy in pp collisions at sqrt(s) = 7 TeV
A search is presented for physics beyond the standard model (BSM) in final
states with a pair of opposite-sign isolated leptons accompanied by jets and
missing transverse energy. The search uses LHC data recorded at a
center-of-mass energy sqrt(s) = 7 TeV with the CMS detector, corresponding to
an integrated luminosity of approximately 5 inverse femtobarns. Two
complementary search strategies are employed. The first probes models with a
specific dilepton production mechanism that leads to a characteristic kinematic
edge in the dilepton mass distribution. The second strategy probes models of
dilepton production with heavy, colored objects that decay to final states
including invisible particles, leading to very large hadronic activity and
missing transverse energy. No evidence for an event yield in excess of the
standard model expectations is found. Upper limits on the BSM contributions to
the signal regions are deduced from the results, which are used to exclude a
region of the parameter space of the constrained minimal supersymmetric
extension of the standard model. Additional information related to detector
efficiencies and response is provided to allow testing specific models of BSM
physics not considered in this paper.Comment: Replaced with published version. Added journal reference and DO
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