10 research outputs found
Missouri Girl Scouts “Downstate” Council
Presented for the Girl Scout Leaders of "Downstate" Council June 22, 2006 Springfield, MO.This OSEDA presentation discusses the Missouri Girl Scouts "Downstate" Council, including age and household structure, various types of diversity and an analysis of Kids Count
Missouri Medicaid Program: A Graphical Profile
Audience: Governor's Medicaid Reform Commission August, 2005.This report provides a graphical summary of the Missouri Medicaid program. It is intended to provide background information of the policy issues being considered by the Missouri Medicaid Reform Commission. Medicaid at the national level is summarized first, and then the report describes Missouri Medicaid. The types of health care services, expenditure levels, and categories of participants are presented. Health care service types are summarized with a focus on overall expenditure levels. Participants are summarized into general enrollment groups: Children, Adults, Blind and Disabled, Elderly, and Other. The interrelationships among services, expenditures and participants are explored using current data and historical trends. County level maps display these patterns for the state. Estimates of the effect of recent changes to the Missouri Medicaid Program are provided. (58 slides
Association between retinal vein occlusion, axial length and vitreous chamber depth measured by optical low coherence reflectometry.
BACKGROUND: Results of ocular biometric measurements in retinal vein occlusion (RVO) eyes are still inconclusive and controversial. The aim of this study was to evaluate the association between ocular axial length (AL), vitreous chamber depth (VCD) and both central (CRVO) and branch retinal vein occlusions (BRVO) using optical low coherence reflectometry (OLCR). METHODS: Both eyes of 37 patients with unilateral CRVO (mean age: 66 +/- 14 years, male:female - 21:16) and 46 patients with unilateral BRVO (mean age: 63 +/- 12 years, male:female - 24:22) were enrolled in this study. The control group consisted of randomly selected single eyes of 67 age and gender matched volunteers without the presence or history of RVO (mean age: 64 +/- 14 years, male:female - 34:33). Optical biometry was performed by OLCR biometer (LenStar LS 900). Average keratometry readings, central corneal thickness (CCT), anterior chamber depth (ACD), lens thickness (LT), AL and VCD of eyes with RVO were compared with those of fellow eyes using paired t-tests and with those of control eyes using independent t-tests. RESULTS: Mean CCT, ACD and LT, average keratometry readings of affected RVO eyes, unaffected fellow eyes and control eyes was not statistically different in either groups. In eyes with CRVO mean AL and VCD of affected eyes were significantly shorter than those of control eyes (p < 0.001, p < 0.05), mean difference in AL and VCD between the affected and control eyes was 0.56 +/- 0.15 mm and 0.45 +/- 0.19 mm, respectively. In eyes with BRVO, mean AL of the affected eyes was significantly shorter with a mean difference of 0.57 +/- 0.15 mm (p < 0.001) and the VCD was significantly shorter with a mean difference of 0.61 +/- 0.15 mm (p < 0.001) comparing with the control eyes. CONCLUSION: Shorter AL and VCD might be a potential anatomical predisposing factor for development either of CRVO or BRVO
An improved map of the Galactic Faraday sky
We aim to summarize the current state of knowledge regarding Galactic Faraday
rotation in an all-sky map of the Galactic Faraday depth. For this we have
assembled the most extensive catalog of Faraday rotation data of compact
extragalactic polarized radio sources to date. In the map making procedure we
use a recently developed algorithm that reconstructs the map and the power
spectrum of a statistically isotropic and homogeneous field while taking into
account uncertainties in the noise statistics. This procedure is able to
identify some rotation angles that are offset by an integer multiple of pi. The
resulting map can be seen as an improved version of earlier such maps and is
made publicly available, along with a map of its uncertainty. For the angular
power spectrum we find a power law behavior with a power law index of -2.14 for
a Faraday sky where an overall variance profile as a function of Galactic
latitude has been removed, in agreement with earlier work. We show that this is
in accordance with a 3D Fourier power spectrum P(k) proportional to k^-2.14 of
the underlying field n_e times B_r under simplifying geometrical and
statistical assumptions.Comment: 16 pages, 11 figures. Update in one data catalog. All results are
available at http://www.mpa-garching.mpg.de/ift/faraday
The effect of cataract on early stage glaucoma detection using spatial and temporal contrast sensitivity tests
Background:
To investigate the effect of cataract on the ability of spatial and temporal contrast sensitivity tests used to detect early glaucoma.
Methods:
Twenty-seven glaucoma subjects with early cataract (mean age 60 ±10.2 years) which constituted the test group were recruited together with twenty-seven controls (cataract only) matched for age and cataract type from a primary eye care setting. Contrast sensitivity to flickering gratings at 20 Hz and stationary gratings with and without glare, were measured for 0.5, 1.5 and 3 cycles per degree (cpd) in central vision. Perimetry and structural measurements with the Heidelberg Retinal Tomograph (HRT) were also performed.
Results:
After considering the effect of cataract, contrast sensitivity to stationary gratings was reduced in the test group compared with controls with a statistically significant mean difference of 0.2 log units independent of spatial frequency. The flicker test showed a significant difference between test and control group at 1.5 and 3 cpd (p = 0.019 and p = 0.011 respectively). The percentage of glaucoma patients who could not see the temporal modulation was much higher compared with their cataract only counterparts. A significant correlation was found between the reduction of contrast sensitivity caused by glare and the Glaucoma Probability Score (GPS) as measured with the HRT (p<0.005).
Conclusions:
These findings indicate that both spatial and temporal contrast sensitivity tests are suitable for distinguishing between vision loss as a consequence of glaucoma and vision loss caused by cataract only. The correlation between glare factor and GPS suggests that there may be an increase in intraocular stray light in glaucoma
Kidney and Cardiovascular Effects of Canagliflozin According to Age and Sex: A Post Hoc Analysis of the CREDENCE Randomized Clinical Trial
Rationale & Objective: It is unclear whether the effect of canagliflozin on adverse kidney and cardiovascular events in those with diabetic kid-ney disease varies by age and sex. We assessed the effects of canagliflozin among age group categories and between sexes in the Canagli-flozin and Renal Endpoints in Diabetes with Established Nephropathy Clinical Evaluation (CREDENCE) study.Study Design: Secondary analysis of a random-ized controlled trial. Setting & Participants: Participants in the CREDENCE trial. Intervention: Participants were randomly assigned to receive canagliflozin 100 mg/d or placebo.Outcomes: Primary composite outcome of kid-ney failure, doubling of serum creatinine con-centration, or death due to kidney or cardiovascular disease. Prespecified secondary and safety outcomes were also analyzed. Out-comes were evaluated by age at baseline (<60, 60-69, and >_70 years) and sex in the intention-to-treat population using Cox regression models.Results: The mean age of the cohort was 63.0 & PLUSMN; 9.2 years, and 34% were female. Older age and female sex were independently associ-ated with a lower risk of the composite of adverse kidney outcomes. There was no evidence that the effect of canagliflozin on the primary outcome (acomposite of kidney failure, a doubling of serum creatinine concentration, or death from kidney or cardiovascular causes) differed between age groups (HRs, 0.67 [95% CI, 0.52-0.87], 0.63 [0.4 8-0.82], and 0.89 [0.61-1.29] for ages <60, 60-69, and >_70 years, respectively; P = 0.3 for interaction) or sexes (HRs, 0.71 [95% CI, 0.5 4-0.95] and 0.69 [0.56-0.8 4] in women and men, respectively; P = 0.8 for interaction). No differences in safety outcomes by age group or sex were observed.Limitations: This was a post hoc analysis with multiple comparisons.Conclusions: Canagliflozin consistently reduced the relative risk of kidney events in people with diabetic kidney disease in both sexes and across age subgroups. As a result of greater background risk, the absolute reduction in adverse kidney outcomes was greater in younger participants.Funding: This post hoc analysis of the CREDENCE trial was not funded. The CREDENCE study was sponsored by Janssen Research and Development and was conducted collaboratively by the sponsor, an academic-led steering committee, and an academic research organization, George Clinical.Trial Registration: The original CREDENCE trial was registered at ClinicalTrials.gov with study number NCT02065791