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67 research outputs found

Genetic variation and linkage disequilibrium in Bacillus anthracis

Author: A Fasanella
A Fouet
AM Mironczuk
AT Kovacs
B Janes
DJ Cutler
E Helgason
EP Rocha
F Tajima
FG Priest
GA Watterson
GAT McVean
H Akashi
J Maynard Smith
JC Barrett
JD Thompson
JP Gomes
KA Jolley
KE Holt
KL Smith
KL Smith
KS Ko
L Radnedge
LB Price
M Achtman
M Touchon
MCJ Maiden
ME Zwick
ME Zwick
MN Van Ert
P Keim
P Keim
PE Chen
PJ Jackson
PJ Jackson
R Hershberg
R Sachidanandam
RR Hudson
S Kryazhimskiy
S Myers
S Suerbaum
SA Sawyer
T Wirth
TD Read
TD Read
X Didelot
X Didelot
X Didelot
Y Tanabe
Publication venue: Nature Publishing Group
Publication date
Field of study

We performed whole-genome amplification followed by hybridization of custom-designed resequencing arrays to resequence 303 kb of genomic sequence from a worldwide panel of 39 Bacillus anthracis strains. We used an efficient algorithm contained within a custom software program, UniqueMER, to identify and mask repetitive sequences on the resequencing array to reduce false-positive identification of genetic variation, which can arise from cross-hybridization. We discovered a total of 240 single nucleotide variants (SNVs) and showed that B. anthracis strains have an average of 2.25 differences per 10,000 bases in the region we resequenced. Common SNVs in this region are found to be in complete linkage disequilibrium. These patterns of variation suggest there has been little if any historical recombination among B. anthracis strains since the origin of the pathogen. This pattern of common genetic variation suggests a framework for recognizing new or genetically engineered strains

Crossref

PubMed Central

HOXB5 expression in oral squamous cell carcinoma

Author: Abate-Shen C
Abou-Elhamd KE
Anneroth G
Bankfalvi A
Bettendorf O
Cazal C
Chen KN
Crijns AP
Décio dos Santos Pinto Junior
Fabio Daumas Nunes
Gehring WJ
Hassan NM
Kelleher FC
Leemans CR
Luciana Fasanella Matizonkas-Antonio
Marcelo Durazzo
Marcia Sampaio Campos
Massano J
Mobasheri MB
Nemeth Z
Nunes FD
Oliver AJ
Owens BM
Redline RW
Renata Tucci
Ruddle FH
Samuel S
Silveira EJ
Stein S
Takahashi Y
Van Oostveen J
Yahagi N
Publication venue: 'FapUNIFESP (SciELO)'
Publication date
Field of study

Crossref

Measurement of the top-quark mass in tt¯ events with dilepton final states in pp collisions at √s = 7 TeV

Author: Abbaneo D.
Abbiendi G.
Abbrescia M.
Abdullin S.
Abdulsalam A.
Acosta D.
Acosta J. G.
Acosta M. Vazquez
Adair A.
Adam N.
Adam W.
Adams M. R.
Adams T.
Adiguzel A.
Adler V.
Adzic P.
Agram J. L.
Aguilar Benitez M.
Aguilo E.
Ahmad M.
Ahmad W. Haj
Ahuja S.
Akchurin N.
Akgun B.
Akgun U.
Akin I. V.
Alagoz E.
Albajar C.
Albayrak E. A.
Albergo S.
Albrow M.
Alcaraz Maestre J.
AldaJunior W. L.
Alexander J.
Aliev T.
Alimena J.
Almeida N.
Alverson G.
Alves A.
Alves G. A.
Amapane N.
Amsler C.
Anagnostou G.
Anastassov A.
Anderson J.
Anderson M.
Andrea J.
Andreev V.
Andreev V.
Andreev Y.u.
Andrews W.
Anghel I. M.
Anh TV
Anjos T. S.
Ansari M. H.
Antonelli L.
Antunes J. Rodrigues
Antunovic Z.
Apanasevich L.
Appelt E.
Apresyan A.
Apyan A.
Arce P.
Arcidiacono R.
Arenton M. W.
Arfaei H.
Argiro S.
Arneodo M.
Arora S.
Asawatangtrakuldee C.
Asghar M. I.
Askew A.
Assran Y.
Ata M.
Attikis A.
Auffray E.
Autermann C.
Auzinger G.
Avdeeva E.
Avery P.
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Azarkin M.
Azhgirey I.
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MESSINEO ALBERTO MARIA
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Publication venue: 'Springer Science and Business Media LLC'
Publication date: 01/01/2012
Field of study

Open Access: This article is distributed under the terms of the Creative Commons Attribution License.-- Chatrchyan, S. et al.The top-quark mass is measured in proton-proton collisions at s√=7 TeV using a data sample corresponding to an integrated luminosity of 5.0 fb−1 collected by the CMS experiment at the LHC. The measurement is performed in the dilepton decay channel tt¯→(ℓ+νℓb)(ℓ−ν¯¯ℓb¯), where ℓ=e,μ. Candidate top-quark decays are selected by requiring two leptons, at least two jets, and imbalance in transverse momentum. The mass is reconstructed with an analytical matrix weighting technique using distributions derived from simulated samples. Using a maximum-likelihood fit, the top-quark mass is determined to be 172.5±0.4 (stat.)±1.5 (syst.) GeV.Acknowledge support from BMWF and FWF (Austria); FNRS and FWO (Belgium); CNPq, CAPES, FAPERJ, and FAPESP (Brazil); MES (Bulgaria); CERN; CAS, MoST, and NSFC (China); COLCIENCIAS (Colombia); MSES (Croatia); RPF (Cyprus); MoER, SF0690030s09 and ERDF (Estonia); Academy of Finland, MEC, and HIP (Finland); CEA and CNRS/IN2P3 (France);BMBF, DFG, and HGF (Germany); GSRT (Greece); OTKA and NKTH (Hungary); DAE and DST (India); IPM (Iran); SFI (Ireland); INFN (Italy); NRF and WCU (Korea); LAS (Lithuania); CINVESTAV, CONACYT, SEP, and UASLP-FAI (Mexico); MSI (New Zealand); PAEC (Pakistan); MSHE and NSC (Poland); FCT (Portugal); JINR (Armenia, Belarus, Georgia, Ukraine, Uzbekistan); MON, RosAtom, RAS and RFBR (Russia); MSTD (Serbia); SEIDI and CPAN (Spain); Swiss Funding Agencies (Switzerland); NSC (Taipei); ThEP, IPST and NECTEC (Thailand); TUBITAK and TAEK (Turkey); NASU (Ukraine); STFC (United Kingdom); DOE and NSF (USA). Individuals have received support from the Marie-Curie program and the European Research Council (European Union); the Leventis Foundation; the A. P. Sloan Foundation; the Alexander von Humboldt Foundation; the Austrian Science Fund (FWF); the Belgian Federal Science Policy Office; the Fonds pour la Formation à la Recherche dans l’Industrie et dans l’Agriculture (FRIA-Belgium); the Agentschap voor Innovatie door Wetenschap en Technologie (IWTBelgium); the Ministry of Education, Youth and Sports (MEYS) of Czech Republic; the Council of Science and Industrial Research, India; the Compagnia di San Paolo (Torino); and the HOMING PLUS program of Foundation for Polish Science, cofinanced from European Union, Regional Development Fund.Peer Reviewe

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Publication venue
Publication date: 01/01/2022
Field of study

ePubs: the open archive for STFC research publications

Search for dark matter produced in association with a Higgs boson decaying to a pair of bottom quarks in proton-proton collisions at root s=13TeV

Author: Aarrestad TK
Abbaneo D
Abbiendi G
Abbrescia M
Abdullah WATW
Abdullin S
Abercrombie D
Acharya H
Acosta D
Acosta JG
Adam W
Adams E
Adams MR
Adams T
Adloff C
Adzic P
Adán DP
Afanasiev S
Agapitos A
Agarwal G
Aggleton R
Agram J-L
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Cifuentes JAB
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Publication venue
Publication date: 01/01/2018
Field of study

A search for dark matter produced in association with a Higgs boson decaying to a pair of bottom quarks is performed in proton-proton collisions at a center-of-mass energy of 13 TeV collected with the CMS detector at the LHC. The analyzed data sample corresponds to an integrated luminosity of 35.9 fb(-1). The signal is characterized by a large missing transverse momentum recoiling against a bottom quark-antiquark system that has a large Lorentz boost. The number of events observed in the data is consistent with the standard model background prediction. Results are interpreted in terms of limits both on parameters of the type-2 two-Higgs doublet model extended by an additional light pseudoscalar boson a (2HDM+a) and on parameters of a baryonic Z simplified model. The 2HDM+a model is tested experimentally for the first time. For the baryonic Z model, the presented results constitute the most stringent constraints to date.Peer reviewe

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A Deep Neural Network for Simultaneous Estimation of b Jet Energy and Resolution

Author: Aarrestad TK
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Publication venue
Publication date: 01/01/2020
Field of study

We describe a method to obtain point and dispersion estimates for the energies of jets arising from b quarks produced in proton-proton collisions at an energy of s = 13 TeV at the CERN LHC. The algorithm is trained on a large sample of simulated b jets and validated on data recorded by the CMS detector in 2017 corresponding to an integrated luminosity of 41 fb - 1 . A multivariate regression algorithm based on a deep feed-forward neural network employs jet composition and shape information, and the properties of reconstructed secondary vertices associated with the jet. The results of the algorithm are used to improve the sensitivity of analyses that make use of b jets in the final state, such as the observation of Higgs boson decay to b b ¯

UCL Discovery

Search for invisible decays of the Higgs boson produced via vector boson fusion in proton-proton collisions at root s=13 TeV

Author: Aarrestad T
Abbaneo D
Abbiendi G
Abbrescia M
Abdelalim A
Abdullin S
Abercrombie D
Abreu A
Acharya H
Acosta D
Acosta HE
Adam W
Adamidis K
Adams E
Adams M
Adams T
Addesa F
Adloff C
Adzic P
Adán DP
Afanasiev S
Agapitos A
Agarwal G
Aggleton R
Agram J
Aguilar-Benitez M
Ahmad A
Ahmad M
Ahmad WH
Ahmed A
Ahuja S
Aimè C
Akchurin N
Akgun B
Akpinar A
Albergo S
Albert A
Albrecht S
Albrow M
Aleksandrov A
Alexander J
Alhusseini M
Alimena J
Alison J
Almond J
Alonso AG
Alpana A
Alvarez JR
Alverson G
Alves BFS
Alves G
Aly R
Alyari M
Amapane N
Amaral SSD
Amarilo KM
Ambrozas M
Amendola C
Amin N
Amram O
Amsler C
An S
An Y
Anagnostou G
Anampa KH
Andrea J
Andreassi G
Andreev V
Andreev Y
Andrejkovic J
Andrews M
Androsov K
Anguiano J
Antchev G
Antequera JB
Anthony D
Antunovic Z
Anuar AB
Apollinari G
Apparu D
Appelt E
Apresyan A
Apyan A
Araujo M
Arcaro D
Arcidiacono R
Arenton M
Argiro S
Arneodo M
Aruta C
Asavapibhop B
Asawatangtrakuldee C
Asenov P
Asghar M
Asilar E
Askew A
Asmuss P
Atakisi I
Attikis A
Auffray E
Aushev T
Auzinger G
Avati V
Avery P
Avila C
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Awan M
Ayala E
Ayala G
Azarkin M
Azhgirey I
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Azzi P
Azzurri P
Baarmand M
Babaev A
Bacchetta N
Bachiller I
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Backhaus M
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Baechler J
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Bakshi A
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Wang S
Wang X
Wang Y
Wang Z
Waqas M
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Warner Z
Wassmer M
Watson I
Wayne M
Webb S
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Zalewski P
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Zarucki M
Zecchinelli A
Zeinali M
Zeuner W
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Zhizhin I
Zhokin A
Zhu R
Ziemons T
Zipper N
Zoi I
Zolkapli Z
Zorbakir I
Zorbilmez C
Zotto P
Zotz A
Zou D
Zou R
Zucchetta A
Zumerle G
Zuo X
Zuolo D
Zygala L
Álvarez CR
Özçelik Ö
Publication venue
Publication date: 01/01/2022
Field of study

ePubs: the open archive for STFC research publications

A review of zoonotic infection risks associated with the wild meat trade in Malaysia.

Author: A Ayouba
A Bruyne De
A Dalsjö
A Deutz
A Durazo
A Fanning
A Fasanella
A Gessain
A Jha
A Kurth
AA Roess
AL Chaber
Anna L. Meredith
AO Kamins
B Carme
B Garin-Bastuji
B Latif
B Ludwig
BD Bhatt
BJ Weigler
BR Scheffers
C Alvarado-Esquivel
C Gill
C Khamboonruang
C Kilonzo
C Starnes
CA Peres
CDC
CJ Hemmer
CM Capitini
CR Friedman
CR Shepherd
CS Madar
D Bell
D Chase
D Giurgiutiu
D Hill
D Tappe
D Warrilow
D-Y Min
Daniel J. Ingram
DC Anderson
DJ Ingram
DK Ekanayake
DS Sharma
E Bennett
E Born
E García
E Gołab
EA Engels
EJ Milner-Gulland
EL Bennett
EM Leroy
F Huang
F Ye
FM Kennedy
GM Liss
GP Holmes
H Akahane
H Fukushima
H Matsuda
H Nagano
H Xu
H Yapo Ette
HY Park
IL Owen
J Chan
J Cui
J Kelly
J Robson
J Schipper
J Wisser
J-I Masuda
JA Brody
JC McDonald
JD Easterbrook
Jennifer Caroline Cantlay
JH Epstein
JI Brooks
JJ Sacks
JL Huff
JM Rounds
JM Yob
JN Hanna
JR Harris
JS Magee
JT Kuhl
K Abernethy
K Kuhn
K Michalak
K Prathap
K Seguchi
K Takahashi
K Toyoda
KB Chua
KB Chua
KE Lane
KJ Smith
KM Eales
KV Shah
L Jones-Engel
L Jones-Engel
L Jones-Engel
LA Kurpiers
LB Forbes
M Addidle
M Baker
M Carrington
M Corrente
M Huffman
M LeBreton
M Li
M Luskin
M Meyer
M Miranda
M Radakovic
M Rosenkranz
M Schweizer
M Wang
M Wilkins
ME Patrick
MH Yao
MJ Irwin
MJ Wilkins
MR Bow
MT Anantaphruti
N Kaewpitoon
N Marano
NA Vashi
ND Wolfe
ND Wolfe
NW Lerche
O Pernet
O Wichmann
OC Or
P Daszak
P Isotalo
P Massey
P Nagel
P Paulsen
P Rabinowitz
PC Fan
PC Fan
PE Rodríguez
PL Kumari
PN Nation
R Atlas
R Drury
R Ichhpujani
R Murphree
R Serrano
R Summer
RA Weiss
RD Ross
RJ Coker
RL Hall
RS Schellenberg
S Diesch
S Esmaeili
S Hussain
S Jittapalapong
S Jongwutiwes
S Maxwell
S Miyazaki
S Morikawa
S Pandit
S Ranque
S Tanaka
S Tei
S Tei
S Thayaparan
SL Greenbloom
SP Luby
SP Luby
SR Favoretto
T Ancelle
T Halaby
T Kuroki
T Kusolsuk
T Li
T Masuzawa
T Rabatsky-Ehr
T Ramasoota
T Yamaguchi
TJ Davies
V Briones
V Nijman
V Wiwanitkit
W Li
WB Karesh
WB Karesh
WB Karesh
WE Keene
WYNHW Choi
X Meng
Y Une
YL Lau
Z Fazly
Z-C Tu
Publication venue: 'Springer Science and Business Media LLC'
Publication date: 01/01/2017
Field of study

The overhunting of wildlife for food and commercial gain presents a major threat to biodiversity in tropical forests and poses health risks to humans from contact with wild animals. Using a recent survey of wildlife offered at wild meat markets in Malaysia as a basis, we review the literature to determine the potential zoonotic infection risks from hunting, butchering and consuming the species offered. We also determine which taxa potentially host the highest number of pathogens and discuss the significant disease risks from traded wildlife, considering how cultural practices influence zoonotic transmission. We identify 51 zoonotic pathogens (16 viruses, 19 bacteria and 16 parasites) potentially hosted by wildlife and describe the human health risks. The Suidae and the Cervidae families potentially host the highest number of pathogens. We conclude that there are substantial gaps in our knowledge of zoonotic pathogens and recommend performing microbial food safety risk assessments to assess the hazards of wild meat consumption. Overall, there may be considerable zoonotic risks to people involved in the hunting, butchering or consumption of wild meat in Southeast Asia, and these should be considered in public health strategies

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University of Melbourne Institutional Repository

Search for dark matter produced in association with a leptonically decaying Z boson in proton–proton collisions at s√=13TeV

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Abbiendi G
Abbrescia M
Abdullah WATW
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Abercrombie D
Acharya H
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Acosta JG
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Adams E
Adams MR
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Adloff C
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Arbelaez NV
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Atakisi IO
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Ather MW
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Álvarez CR
Özçelik Ö
Publication venue: 'Springer Science and Business Media LLC'
Publication date: 07/12/2020
Field of study

A search for dark matter particles is performed using events with a Z boson candidate and large missing transverse momentum. The analysis is based on proton–proton collision data at a center-of-mass energy of 13TeV, collected by the CMS experiment at the LHC in 2016–2018, corresponding to an integrated luminosity of 137fb−1. The search uses the decay channels Z→ee and Z→μμ. No significant excess of events is observed over the background expected from the standard model. Limits are set on dark matter particle production in the context of simplified models with vector, axial-vector, scalar, and pseudoscalar mediators, as well as on a two-Higgs-doublet model with an additional pseudoscalar mediator. In addition, limits are provided for spin-dependent and spin-independent scattering cross sections and are compared to those from direct-detection experiments. The results are also interpreted in the context of models of invisible Higgs boson decays, unparticles, and large extra dimensions.SCOAP

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Adán DP
Afanasiev S
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Banos LIE
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Bhal E
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Bharthuar S
Bharti M
Bhat PC
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Bhattacharya R
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Cerati GB
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Chen C
Chen GM
Chen HS
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Chenarani S
Cheng C
Cheng T
Cheng Y
Cherepanov V
Chernyavskaya N
Chertok M
Cheung HWK
Chhibra SS
Chiarito B
Chinellato J
Chlebana F
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Choudhary BC
Chowdhury SR
Christoforou K
Chudasama R
Chwalek T
Ciangottini D
Cifuentes JAB
Ciocci MA
Cipriani M
Ciriolo V
Citron M
Cittolin S
Ciulli V
Civinini C
Claes DR
Clare R
Clement E
Clerbaux B
Cockerill DJA
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Colaleo A
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Cornelis T
Cortezon EP
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Covarelli R
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Cruz SS
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Dewanjee RK
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Dharmaratna WGD
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Diaz D
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González CAS
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Álvarez CR
Özçelik Ö
Publication venue: 'American Physical Society (APS)'
Publication date: 26/04/2022
Field of study

The leptonic and inclusive hadronic decay branching fractions of the W boson are measured using proton-proton collision data collected at ffiffi s p ¼ 13 TeV by the CMS experiment at the CERN LHC, corresponding to an integrated luminosity of 35.9 fb−1. Events characterized by the production of one or two W bosons are selected and categorized based on the multiplicity and flavor of reconstructed leptons, the number of jets, and the number of jets identified as originating from the hadronization of b quarks. A binned maximum likelihood estimate of the W boson branching fractions is performed simultaneously in each event category. The measured branching fractions of the W boson decaying into electron, muon, and tau lepton final states are ð10.83 0.10Þ%, ð10.94 0.08Þ%, and ð10.77 0.21Þ%, respectively, consistent with lepton flavor universality for the weak interaction. The average leptonic and inclusive hadronic decay branching fractions are estimated to be ð10.89 0.08Þ% and ð67.32 0.23Þ%, respec tively. Based on the hadronic branching fraction, three standard model quantities are subsequently derived: the sum of squared elements in the first two rows of the Cabibbo–Kobayashi–Maskawa (CKM) matrix P ij jVijj 2 ¼ 1.984 0.021, the CKM element jVcsj ¼ 0.967 0.011, and the strong coupling constant at the W boson mass scale, αSðm2 WÞ ¼ 0.095 0.033

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