Glucocorticoids are lower at delivery in maternal, but not cord blood of obese pregnancies

Abstract Glucocorticoids are vital for lung maturation. We previously showed that cortisol is lower in obese pregnancy. Whether this is maintained at delivery is unknown but is clinically relevant as maternal and cord blood cortisol levels are correlated and offspring of obese are more likely to need neonatal respiratory support. We hypothesized that glucocorticoids are lower in maternal and cord blood at delivery in obese pregnancies. Glucocorticoids (cortisol and corticosterone) and their inactive versions (cortisone and 11-dehydrocorticosterone) were measured by LC-MS/MS in maternal and cord plasma from 259 Caucasian women at delivery (BMI 18–55 kg/m2). Analyses adjusted for labour status, delivery mode, offspring gender, birthweight and gestational age. Cortisol and corticosterone were significantly higher in maternal than cord blood. Inactive versions were significantly higher in cord than maternal blood. Increased maternal BMI associated with lower maternal cortisol, corticosterone and 11-dehydrocorticosterone. Despite significant positive correlations between maternal and cord blood glucocorticoid levels, increased maternal BMI was not associated with lower cord blood glucocorticoid levels. Conditions at delivery may overcome any potential negative effects of low maternal glucocorticoids on the fetus in the short-term. This may not preclude the longer-term effects of fetal exposure to lower glucocorticoid levels during obese pregnancy

Precision Mass Measurements of 129-131Cd and Their Impact on Stellar Nucleosynthesis via the Rapid Neutron Capture Process

Masses adjacent to the classical waiting-point nuclide 130Cd have been measured by using the Penning- trap spectrometer ISOLTRAP at ISOLDE/CERN. We find a significant deviation of over 400 keV from earlier values evaluated by using nuclear beta-decay data. The new measurements show the reduction of the N = 82 shell gap below the doubly magic 132Sn. The nucleosynthesis associated with the ejected wind from type-II supernovae as well as from compact object binary mergers is studied, by using state-of-the-art hydrodynamic simulations. We find a consistent and direct impact of the newly measured masses on the calculated abundances in the A = 128 - 132 region and a reduction of the uncertainties from the precision mass input data

The XMM-Newton Wide Angle Survey (XWAS): the X-ray spectrum of type-1 AGN

We discuss the broad band X-ray properties of one of the largest samples of X-ray selected type-1 AGN to date (487 objects in total), drawn from the XMM-Newton Wide Angle Survey. The objects cover 2-10 keV luminosities from ~10^{42}-10^{45} erg s^{-1} and are detected up to redshift ~4. We constrain the overall properties of the broad band continuum, soft excess and X-ray absorption, along with their dependence on the X-ray luminosity and redshift and we discuss the implications for models of AGN emission. We constrained the mean spectral index of the broad band X-ray continuum to =1.96+-0.02 with intrinsic dispersion sigma=0.27_{-0.02}^{+0.01}. The continuum becomes harder at faint fluxes and at higher redshifts and luminosities. The dependence of Gamma with flux is likely due to undetected absorption rather than to spectral variation. We found a strong dependence of the detection efficiency of objects on the spectral shape which can have a strong impact on the measured mean continuum shapes of sources at different redshifts and luminosities. We detected excess absorption in ~3% of our objects, with column densities ~a few x10^{22} cm^{-2}. The apparent mismatch between the optical classification and X-ray properties of these objects is a challenge for the standard AGN unification model. We found that the fraction of objects with detected soft excess is ~36%. Using a thermal model, we constrained the soft excess mean temperature and intrinsic dispersion to ~100 eV and sigma~34 eV. The origin of the soft excess as thermal emission from the accretion disk or Compton scattered disk emission is ruled out on the basis of the temperatures detected and the lack of correlation of the measured temperature with the X-ray luminosity (abridged).Comment: 13 pages, 24 figures, Accepted for publication in Astronomy and Astrophysic

CAIXA: a Catalogue of AGN In the XMM-Newton Archive II. Multiwavelength correlations

We presented CAIXA, a Catalogue of AGN in the XMM-Newton Archive, in a companion paper. Here, a systematic search for correlations between the X-ray spectral properties and the multiwavelength data was performed for the sources in CAIXA. All the significant (>99.9% confidence level) correlations are discussed along with their physical implications on current models of AGN. Two main correlations are discussed in this paper: a) a very strong anti-correlation between the FWHM of the H$\beta$ optical line and the ratio between the soft and the hard X-ray luminosity. Although similar anti-correlations between optical line width and X-ray spectral steepness have already been discussed in the literature (see e.g., Laor et al. 1994, Boller et al. 1996, Brandt et al. 1997), we consider the formulation we present in this paper is more fundamental, as it links model-independent quantities. Coupled with a strong anti-correlation between the V to hard X-ray flux ratio and the H$\beta$ FHWM, it supports scenarios for the origin of the soft excess in AGN, which require strong suppression of the hard X-ray emission; b) a strong (and expected) correlation between the X-ray luminosity and the black hole mass. Its slope, flatter than 1, is consistent with Eddington ratio-dependent bolometric corrections, such as that recently proposed by Vasudevan & Fabian (2009). Moreover, we critically review through various statistical tests the role that distance biases play in the strong radio to X-ray luminosity correlation found in CAIXA and elsewhere; we conclude that only complete, unbiased samples (such as that recently published by Behar & Laor, 2008) should be used to draw observational constraints on the origin of radio emission in radio-quiet AGN.Comment: 12 pages, 11 figures, accepted for publication in Astronomy and Astrophysics; two figures erroneously attached by astroph to the paper were remove

Investigating the complex X-ray spectrum of a broad-line 2MASS red quasar: XMM-Newton observation of FTM 0830+3759

We report results from a 50 ks XMM-Newton observation of the dust-reddened broad-line quasar FTM 0830+3759 (z=0.413) selected from the FIRST/2MASS Red Quasar survey. For this AGN, a very short 9 ks Chandra exposure had suggested a feature-rich X-ray spectrum and HST images revealed a very disturbed host galaxy morphology. Contrary to classical, optically-selected quasars, the X-ray properties of red (i.e. with J-Ks> 1.7 and R-Ks> 4) broad line quasars are still quite unexplored, although there is a growing consensus that, due to moderate obscuration, these objects can offer a unique view of spectral components typically swamped by the AGN light in normal, blue quasars. The XMM-Newton observation discussed here has definitely confirmed the complexity of the X-ray spectrum revealing the presence of a cold (or mildly-ionized) absorber with Nh ~10^{22} cm^-2 along the line of sight to the nucleus and a Compton reflection component accompanied by an intense Fe K emission line in this quasar with a Lum(2-10) ~5 x 10^{44} erg/s. A soft-excess component is also required by the data. The match between the column density derived by our spectral analysis and that expected on the basis of reddening due to the dust suggests the possibility that both absorptions occur in the same medium. FTM 0830+3759 is characterized by an extinction/absorption-corrected X-ray-to-optical flux ratio alphaox = -2.3, that is steeper than expected on the basis of its UV luminosity. These findings indicate that the X-ray properties of FTM 0830+3759 differs from those typically observed for optically-selected broad line quasars with comparable hard X-ray luminosity.Comment: Accepted for publication in Ap

Multi-epoch X-ray observations of the Seyfert 1.2 galaxy Mrk 79: bulk motion of the illuminating X-ray source

Multi-epoch X-ray spectroscopy (0.3-25 keV) of the Seyfert 1.2 galaxy Mrk 79 (UGC 3973) spanning nearly eight years and a factor of three in broadband flux are analysed. The data are obtained at seven epochs with either XMM-Newton or Suzaku. Comparison with contemporaneous RXTE monitoring indicate that all flux states of Mrk 79 are represented by the data. The spectra are fitted in a self-consistent manner adopting a power law and ionised reflection to describe the broadband continuum. Modification of the spectra by a distant photoionised medium, seen predominantly in emission, are also included. Under the assumption that the inner disk is at the innermost stable circular orbit, our blurred reflection models give a spin of a = 0.7+/-0.1. The reflection component in each spectrum is weaker than predicted by simple reflection models. If the illuminating X-ray emission is produced by flares above the disk that move at mildly relativistic velocities, however, diminished reflection is expected. Light bending due to strong gravity near black holes can influence how the illuminating and reflected flux are observed; variations in Mrk 79 do not suggest that light bending is important in this source.Comment: 13 pages. Accepted for publication in MNRA

A Quasar Catalog with Simultaneous UV, Optical and X-ray Observations by Swift

We have compiled a catalog of optically-selected quasars with simultaneous observations in UV/optical and X-ray bands by the Swift Gamma Ray Burst Explorer. Objects in this catalog are identified by matching the Swift pointings with the Sloan Digital Sky Survey Data Release 5 quasar catalog. The final catalog contains 843 objects, among which 637 have both UVOT and XRT observations and 354 of which are detected by both instruments. The overall X-ray detection rate is ~60% which rises to ~85% among sources with at least 10 ks of XRT exposure time. We construct the time-averaged spectral energy distribution for each of the 354 quasars using UVOT photometric measurements and XRT spectra. From model fits to these SEDs, we find that the big blue bump contributes about 0.3 dex to the quasar luminosity. We re-visit the alpha_ox-L_uv relation by selecting a clean sample with only type 1 radio-quiet quasars; the dispersion of this relation is reduced by at least 15% compared to studies that use non-simultaneous UV/optical and X-ray data. We only found a weak correlation between L/L_Edd and alpha_uv. We do not find significant correlations between alpha_x and alpha_ox, alpha_ox and alpha_uv, and alpha_x and Log L(0.3-10 keV). The correlations between alpha_uv and alpha_x, alpha_ox and alpha_x, alpha_ox and alpha_uv, L/L_Edd and alpha_x, and L/L_Edd and alpha_ox are stronger amongst low-redshift quasars, indicating that these correlations are likely driven by the changes of SED shape with accretion state.Comment: 63 pages, 22 figures, accepted by ApJ