7 research outputs found

    Finishing the euchromatic sequence of the human genome

    Get PDF
    The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead

    Design of an air track for engineering and physics education

    No full text
    Thesis: S.B., Massachusetts Institute of Technology, Department of Mechanical Engineering, 2014.Cataloged from PDF version of thesis.Includes bibliographical references (pages 47-48).An air track is a valuable tool for examining force and motion in the classroom, providing a low-friction environment to observe phenomena. Unfortunately, currently available models have limited functionality and are prohibitively expensive for many schools. To improve access to this helpful device, a number of smaller and less expensive variations on traditional air tracks are designed and tested. From an analysis of test results and theoretical performance calculations, the best design is identified. Further improvements to this design are also suggested.by Jeremy Ernest deGuzman.S.B

    Harsh Justice for International Crimes?

    No full text

    ACC/AHA guidelines for the management of patients with acute myocardial infarction

    No full text
    corecore