A cluster randomised feasibility study of an adolescent incentive intervention to increase uptake of HPV vaccination.

BACKGROUND: Uptake of human papillomavirus (HPV) vaccination is suboptimal among some groups. We aimed to determine the feasibility of undertaking a cluster randomised controlled trial (RCT) of incentives to improve HPV vaccination uptake by increasing consent form return. METHODS: An equal-allocation, two-arm cluster RCT design was used. We invited 60 London schools to participate. Those agreeing were randomised to either a standard invitation or incentive intervention arm, in which Year 8 girls had the chance to win a £50 shopping voucher if they returned a vaccination consent form, regardless of whether consent was provided. We collected data on school and parent participation rates and questionnaire response rates. Analyses were descriptive. RESULTS: Six schools completed the trial and only 3% of parents opted out. The response rate was 70% for the girls' questionnaire and 17% for the parents'. In the intervention arm, 87% of girls returned a consent form compared with 67% in the standard invitation arm. The proportion of girls whose parents gave consent for vaccination was higher in the intervention arm (76%) than the standard invitation arm (61%). CONCLUSIONS: An RCT of an incentive intervention is feasible. The intervention may improve vaccination uptake but a fully powered RCT is needed.British Journal of Cancer advance online publication: 22 August 2017; doi:10.1038/bjc.2017.284 www.bjcancer.com

Emerging topics in nanophononics and elastic, acoustic, and mechanical metamaterials:An overview

This broad review summarizes recent advances and “hot” research topics in nanophononics and elastic, acoustic, and mechanical metamaterials based on results presented by the authors at the EUROMECH 610 Colloquium held on April 25–27, 2022 in Benicássim, Spain. The key goal of the colloquium was to highlight important developments in these areas, particularly new results that emerged during the last two years. This work thus presents a “snapshot” of the state-of-the-art of different nanophononics- and metamaterial-related topics rather than a historical view on these subjects, in contrast to a conventional review article. The introduction of basic definitions for each topic is followed by an outline of design strategies for the media under consideration, recently developed analysis and implementation techniques, and discussions of current challenges and promising applications. This review, while not comprehensive, will be helpful especially for early-career researchers, among others, as it offers a broad view of the current state-of-the-art and highlights some unique and flourishing research in the mentioned fields, providing insight into multiple exciting research directions

The Sloan Digital Sky Survey Reverberation Mapping Project: Initial C IV lag results from four years of data

K.H. acknowledges support from STFC grant ST/M001296/1.We present reverberation-mapping (RM) lags and black hole mass measurements using the C iv λ1549 broad emission line from a sample of 348 quasars monitored as a part of the Sloan Digital Sky Survey RM Project. Our data span four years of spectroscopic and photometric monitoring for a total baseline of 1300 days, allowing us to measure lags up to ~750 days in the observed frame (this corresponds to a rest-frame lag of ~300 days in a quasar at z = 1.5 and ~190 days at z = 3). We report significant time delays between the continuum and the C iv λ1549 emission line in 48 quasars, with an estimated false-positive detection rate of 10%. Our analysis of marginal lag measurements indicates that there are on the order of ~100 additional lags that should be recoverable by adding more years of data from the program. We use our measurements to calculate black hole masses and fit an updated C iv radius–luminosity relationship. Our results significantly increase the sample of quasars with C iv RM results, with the quasars spanning two orders of magnitude in luminosity toward the high-luminosity end of the C iv radius–luminosity relation. In addition, these quasars are located at some of the highest redshifts (z ≈ 1.4–2.8) of quasars with black hole masses measured with RM. This work constitutes the first large sample of C iv RM measurements in more than a dozen quasars, demonstrating the utility of multiobject RM campaigns.Publisher PDFPeer reviewe

The First Post-Kepler Brightness Dips of KIC 8462852

We present a photometric detection of the first brightness dips of the unique variable star KIC 8462852 since the end of the Kepler space mission in 2013 May. Our regular photometric surveillance started in October 2015, and a sequence of dipping began in 2017 May continuing on through the end of 2017, when the star was no longer visible from Earth. We distinguish four main 1-2.5% dips, named "Elsie," "Celeste," "Skara Brae," and "Angkor", which persist on timescales from several days to weeks. Our main results so far are: (i) there are no apparent changes of the stellar spectrum or polarization during the dips; (ii) the multiband photometry of the dips shows differential reddening favoring non-grey extinction. Therefore, our data are inconsistent with dip models that invoke optically thick material, but rather they are in-line with predictions for an occulter consisting primarily of ordinary dust, where much of the material must be optically thin with a size scale <<1um, and may also be consistent with models invoking variations intrinsic to the stellar photosphere. Notably, our data do not place constraints on the color of the longer-term "secular" dimming, which may be caused by independent processes, or probe different regimes of a single process

The Sloan Digital Sky Survey Reverberation Mapping Project : improving lag detection with an extended multiyear baseline

We investigate the effects of extended multiyear light curves (9 yr photometry and 5 yr spectroscopy) on the detection of time lags between the continuum variability and broad-line response of quasars at z ≳ 1.5, and compare with the results using 4 yr photometry+spectroscopy presented in a companion paper. We demonstrate the benefits of the extended light curves in three cases: (1) lags that are too long to be detected by the shorter-duration data but can be detected with the extended data; (2) lags that are recovered by the extended light curves but are missed in the shorter-duration data due to insufficient light-curve quality; and (3) lags for different broad-line species in the same object. These examples demonstrate the importance of long-term monitoring for reverberation mapping to detect lags for luminous quasars at high redshift, and the expected performance of the final data set from the Sloan Digital Sky Survey Reverberation Mapping project that will have 11 yr photometric and 7 yr spectroscopic baselines.Publisher PDFPeer reviewe