38 research outputs found

    HIV/AIDS epidemiology, pathogenesis, prevention, and treatment.

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    The HIV-1 pandemic is a complex mix of diverse epidemics within and between countries and regions of the world, and is undoubtedly the defining public-health crisis of our time. Research has deepened our understanding of how the virus replicates, manipulates, and hides in an infected person. Although our understanding of pathogenesis and transmission dynamics has become more nuanced and prevention options have expanded, a cure or protective vaccine remains elusive. Antiretroviral treatment has transformed AIDS from an inevitably fatal condition to a chronic, manageable disease in some settings. This transformation has yet to be realised in those parts of the world that continue to bear a disproportionate burden of new HIV-1 infections and are most affected by increasing morbidity and mortality. This Seminar provides an update on epidemiology, pathogenesis, treatment, and prevention interventions pertinent to HIV-1

    Stereotype threat and hazard perception among provisional license drivers

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    Stereotype threat refers to the negative impact a stereotype about one’s group can have on one’s performance in domains relevant to the stereotype. In the current paper, we explore whether the negative stereotype of provisional license drivers (PLDs) might produce stereotype threat in a driving-related hazard perception task. We manipulate threat by asking participants to self-identify as PLDs in a categorization condition, or by reminding PLD participants explicitly of the stereotype of PLDs in an explicit stereotype condition. Results reveal increments in hazard perception in the categorization condition, and decrements in hazard perception in the explicit stereotype condition. Mediation analysis reveals that hazard perception performance is fully mediated by increased effort in the categorization condition and by decreased effort in the explicit stereotype condition. We discuss these findings in terms of their implications for stereotype threat and its mediators, and for public policy that explicitly discriminates between PLDs and other driver groups
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