Gastrointestinal neuromuscular apparatus: An underestimated target of gut microbiota

Over the last few years, the importance of the resident intestinal microbiota in the pathogenesis of several gastro- intestinal diseases has been largely investigated. Growing evidence suggest that microbiota can influence gastro- intestinal motility. The current working hypothesis is that dysbiosis-driven mucosal alterations induce the production of several inflammatory/immune mediators which affect gut neuro-muscular functions. Besides these indirect mucosal-mediated effects, the present review highlights that recent evidence suggests that microbiota can directly affect enteric nerves and smooth muscle cells functions through its metabolic products or bacterial molecular components translocated from the intestinal lumen. Toll- like receptors, the bacterial recognition receptors, are expressed both on enteric nerves and smooth muscle and are emerging as potential mediators between microbiota and the enteric neuromuscular apparatus. Furthermore, the ongoing studies on probiotics support the hypothesis that the neuromuscular apparatus may represent a target of intervention, thus opening new physiopathological and therapeutic scenarios

Chapter Testimoniare attraverso il rilievo. Segni e storia del Palazzo Conca a Napoli

The 43rd UID conference, held in Genova, takes up the theme of ‘Dialogues’ as practice and debate on many fundamental topics in our social life, especially in these complex and not yet resolved times. The city of Genova offers the opportunity to ponder on the value of comparison and on the possibilities for the community, naturally focused on the aspects that concern us, as professors, researchers, disseminators of knowledge, or on all the possibile meanings of the discipline of representation and its dialogue with ‘others’, which we have broadly catalogued in three macro areas: History, Semiotics, Science / Technology. Therefore, “dialogue” as a profitable exchange based on a common language, without which it is impossible to comprehend and understand one another; and the graphic sign that connotes the conference is the precise transcription of this concept: the title ‘translated’ into signs, derived from the visual alphabet designed for the visual identity of the UID since 2017. There are many topics which refer to three macro sessions: - Witnessing (signs and history) - Communicating (signs and semiotics) - Experimenting (signs and sciences) Thanks to the different points of view, an exceptional resource of our disciplinary area, we want to try to outline the prevailing theoretical-operational synergies, the collaborative lines of an instrumental nature, the recent updates of the repertoires of images that attest and nourish the relations among representation, history, semiotics, sciences

La representación verbal y visual de la belleza y la fealdad en dos ensayos editados por Umberto Eco

El presente artículo se propone recorrer algunas etapas del fascinante viaje realizado por Umberto Eco en dos ensayos editados por él, Historia de la belleza (2004) e Historia de la fealdad (2007), y destacar los recursos con los cuales, en un admirable trenzado de imágenes y palabras, realiza un recorrido por la cultura occidental desde un punto de vista iconográfico y la comenta en el plano filosófico y literario. Con un acercamiento interdisciplinar e intertextual y mediante una escritura a partir de caracteres hipertextuales se invita al lector a profundizar en interesantes aspectos temáticos y a reflexionar sobre su modalidad de representación verbal y visual

The Effect of Perceived Salesperson Transparency, as Enabled by Technology, on Unethical Salesperson Behavior

Recent technological developments have enabled sales managers to increase the behavioral transparency of their sales force. This study focuses on the impact that salesperson perceptions of their own transparency has on the ethicality of their behavior. Perceived transparency is broken down into two dimensions: access to and use of information by management. Empirical support is shown that perceived use of information has a mediating effect on the relationship between perceived managerial access to information and the likelihood of unethical salesperson behavior. Further, bothsubjective salesperson job performance and salesperson control beliefs are shown to have moderating effects on the interaction between use of information and likelihood of unethical salesperson behavior