792 research outputs found
Tactical Voting in Plurality Elections
How often will elections end in landslides? What is the probability for a
head-to-head race? Analyzing ballot results from several large countries rather
anomalous and yet unexplained distributions have been observed. We identify
tactical voting as the driving ingredient for the anomalies and introduce a
model to study its effect on plurality elections, characterized by the relative
strength of the feedback from polls and the pairwise interaction between
individuals in the society. With this model it becomes possible to explain the
polarization of votes between two candidates, understand the small margin of
victories frequently observed for different elections, and analyze the polls'
impact in American, Canadian, and Brazilian ballots. Moreover, the model
reproduces, quantitatively, the distribution of votes obtained in the Brazilian
mayor elections with two, three, and four candidates.Comment: 7 pages, 4 figure
Retinal nerve fibre layer thickness profile in normal eyes using third-generation optical coherence tomography
Aims To establish four normal retinal nerve fibre layer (RNFL) thickness radial profiles based on third-generation optical coherence tomography (OCT) and to compare them with previously reported histologic measurements.Methods A total of 20 normal eyes were studied. A circular scan was adjusted to the size of the optic disc and three scans were performed with this radius and every 200 mu m thereafter, up to a distance of 1400 mu m. Four different radial sections (superotemporal, superonasal, inferonasal, and inferotemporal) were studied to establish RNFL thickness OCT profiles. Additionally, two radial scans orientated at 45 and 1351 crossing the optic disc centre were performed in six of 20 eyes, and RNFL thickness was measured at disc margin.Results Quadrant location and distance from disc margin interaction in RNFL thickness was statistically significant (P < 0.001). the RNFL thickness decreased (P < 0.001) as the distance from the disc margin increased for all sections. the measurements automatically generated by the OCT built-in software were thinner (P < 0.001) than histologic ones close to the disc margin.Conclusions Four normal OCT RNFL profiles were established and compared with histological data obtained from the same area. RNFL measurements assessed by OCT 3 were significantly thinner close to the optic disc margin.Hosp Olhos Araraquara, Glaucoma Sect, BR-14802530 Araraquara, SP, BrazilHosp Olhos Araraquara, Retina Diagnost & Treatment Div, BR-14802530 Araraquara, SP, BrazilUniversidade Federal de São Paulo, São Paulo, BrazilUSP, Inst Fis Sao Carlos, Sao Carlos, SP, BrazilUniv So Calif, Doheny Eye Inst, Dept Ophthalmol, Los Angeles, CA USAUniversidade Federal de São Paulo, São Paulo, BrazilWeb of Scienc
Portuguese recommendations for the use of biological therapies in patients with psoriatic arthritis - 2015 update
OBJECTIVE: To update recommendationsforthe treatment
of psoriatic arthritis with biological therapies, endorsed
by the Portuguese Society of Rheumatology (SPR).
METHODS: These treatment recommendations were formulated
by Portuguese rheumatologists based on literature
evidence and consensus opinion. At a national
meeting the 16 recommendations included in this
document were discussed and updated. The level of
agreement among Portuguese Rheumatologists was assessed
using an online survey. A draft of the full text of
the recommendations was then circulated and suggestions
were incorporated. A final version was again circulated
before publication.
RESULTS: A consensus was achieved regarding the initiation,
assessment of response and switching biological
therapies in patients with psoriatic arthritis (PsA).
Specific recommendations were developed for several
disease domains: peripheral arthritis, axial disease, enthesitis
and dactylitis.
CONCLUSION: These recommendations may be used for
guidance in deciding which patients with PsA should be
treated with biological therapies. They cover a rapidly
evolving area oftherapeutic intervention.Asmore evidence
becomes available and more biological therapies are licensed,
these recommendations will have to be updated
Measurement of the t(t)over-bar production cross section in the dilepton channel in pp collisions at √s=8 TeV
The top-antitop quark (t (t) over bar) production cross section is measured in proton-proton collisions at root s = 8 TeV with the CMS experiment at the LHC, using a data sample corresponding to an integrated luminosity of 5.3 fb(-1). The measurement is performed by analysing events with a pair of electrons or muons, or one electron and one muon, and at least two jets, one of which is identified as originating from hadronisation of a bottom quark. The measured cross section is 239 +/- 2 (stat.) +/- 11 (syst.) +/- 6 (lum.) pb, for an assumed top-quark mass of 172.5 GeV, in agreement with the prediction of the standard model
Performance of CMS muon reconstruction in pp collision events at sqrt(s) = 7 TeV
The performance of muon reconstruction, identification, and triggering in CMS
has been studied using 40 inverse picobarns of data collected in pp collisions
at sqrt(s) = 7 TeV at the LHC in 2010. A few benchmark sets of selection
criteria covering a wide range of physics analysis needs have been examined.
For all considered selections, the efficiency to reconstruct and identify a
muon with a transverse momentum pT larger than a few GeV is above 95% over the
whole region of pseudorapidity covered by the CMS muon system, abs(eta) < 2.4,
while the probability to misidentify a hadron as a muon is well below 1%. The
efficiency to trigger on single muons with pT above a few GeV is higher than
90% over the full eta range, and typically substantially better. The overall
momentum scale is measured to a precision of 0.2% with muons from Z decays. The
transverse momentum resolution varies from 1% to 6% depending on pseudorapidity
for muons with pT below 100 GeV and, using cosmic rays, it is shown to be
better than 10% in the central region up to pT = 1 TeV. Observed distributions
of all quantities are well reproduced by the Monte Carlo simulation.Comment: Replaced with published version. Added journal reference and DO
Performance of CMS muon reconstruction in pp collision events at sqrt(s) = 7 TeV
The performance of muon reconstruction, identification, and triggering in CMS
has been studied using 40 inverse picobarns of data collected in pp collisions
at sqrt(s) = 7 TeV at the LHC in 2010. A few benchmark sets of selection
criteria covering a wide range of physics analysis needs have been examined.
For all considered selections, the efficiency to reconstruct and identify a
muon with a transverse momentum pT larger than a few GeV is above 95% over the
whole region of pseudorapidity covered by the CMS muon system, abs(eta) < 2.4,
while the probability to misidentify a hadron as a muon is well below 1%. The
efficiency to trigger on single muons with pT above a few GeV is higher than
90% over the full eta range, and typically substantially better. The overall
momentum scale is measured to a precision of 0.2% with muons from Z decays. The
transverse momentum resolution varies from 1% to 6% depending on pseudorapidity
for muons with pT below 100 GeV and, using cosmic rays, it is shown to be
better than 10% in the central region up to pT = 1 TeV. Observed distributions
of all quantities are well reproduced by the Monte Carlo simulation.Comment: Replaced with published version. Added journal reference and DO
Effect of age, sex and gender on pain sensitivity: A narrative review
© 2017 Eltumi And Tashani. Introduction: An increasing body of literature on sex and gender differences in pain sensitivity has been accumulated in recent years. There is also evidence from epidemiological research that painful conditions are more prevalent in older people. The aim of this narrative review is to critically appraise the relevant literature investigating the presence of age and sex differences in clinical and experimental pain conditions. Methods: A scoping search of the literature identifying relevant peer reviewed articles was conducted on May 2016. Information and evidence from the key articles were narratively described and data was quantitatively synthesised to identify gaps of knowledge in the research literature concerning age and sex differences in pain responses. Results: This critical appraisal of the literature suggests that the results of the experimental and clinical studies regarding age and sex differences in pain contain some contradictions as far as age differences in pain are concerned. While data from the clinical studies are more consistent and seem to point towards the fact that chronic pain prevalence increases in the elderly findings from the experimental studies on the other hand were inconsistent, with pain threshold increasing with age in some studies and decreasing with age in others. Conclusion: There is a need for further research using the latest advanced quantitative sensory testing protocols to measure the function of small nerve fibres that are involved in nociception and pain sensitivity across the human life span. Implications: Findings from these studies should feed into and inform evidence emerging from other types of studies (e.g. brain imaging technique and psychometrics) suggesting that pain in the older humans may have unique characteristics that affect how old patients respond to intervention
Reverse micelles with spines: L-2 phases of surfactant ion-polyion complex salts, n-alcohols and water investigated by rheology, NMR diffusion and SAXS measurements
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Homogeneous alcoholic isotropic solutions (L-2 phases) of "complex salts'' of hexadecyltrimethylammonium neutralized by polyacrylate CTAPA(n) (n = 30 or 6000), in the presence of water were examined at 25 degrees C by means of small-angle X-ray scattering (SAXS), rheology and NMR self-diffusion measurements for different n-alcohols (octanol, hexanol and butanol) and at varying water contents. The greater water solubility and the slower water self-diffusion coefficients in these L-2 phases, when compared to results with surfactant-free alcohols, suggested that these phases are composed of reverse aggregates with water in their cores. A comparatively rapid self-diffusion of the surfactant ion in butanol suggested a significant fraction of "free'' surfactant ions, dissociated from the reverse aggregates. Rheological data confirmed that the obtained viscoelastic properties were consistent with a system containing entangled elongated micelles, whose properties were controlled by the polyion chain length. NMR diffusion measurements for complex salt solutions with the shorter counter-polyion (CTAPA(30)) produced estimates of the aggregate lengths that were close to the extended length of one PA(30) chain. In summary, these results support the formation of aggregates composed by surfactant decorated polyion chains with a water core, whose properties are determined by the polyion chain length, behaving like reverse micelles with spines.61144153Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Swedish Research CouncilFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP
From global to local: reshoring for sustainability
The UK clothing industry has seen the extensive offshoring of manufacturing, which has created fragmented global supply chains; these present a range of supply issues and challenges, including many related to sustainability. Reshoring is a reversion of a previous offshoring decision, thereby ‘bringing manufacturing back home’ (Gray et al. J Supply Chain Management 49(2):27–33, 2013), and can be motivated by increased costs and supply management problems. While not a new phenomenon, the reshoring of activities is growing in practice and there is an imperative for academic research (Fratocchi et al. J Purch Supply Manag 20:54–59, 2014). Through an in-depth longitudinal case study, this paper explores how sustainability can be addressed through reshoring; the studied UK-based clothing SME has strong principles and is explicitly committed to bringing its supply chain ‘home’. There is a recognised need for more OM research using a social lens (Burgess and Singh Oper Manag Res 5:57–68, 2012), so Social Network Theory (SNT) is employed to examine the reshoring decision-making process. SNT applies a relational, qualitative approach to understand the interactions between network actors, and focuses on the types and strengths of relationships and how they provide context for decisions (Galaskiewicz J Supply Chain Manag 47(1):4–8, 2011). The findings demonstrate the importance of socially complex, long-term relationships in managing a sustainable supply network. These relationships contribute to the resources that a firm can harness in its supply practices, and SNT extends this with its emphasis on the strength of ties with suppliers, and the trust, reciprocity and shared meanings it engenders. For the studied firm these advantages are derived through its localised supply chain, and collaborative supplier relationships, and its progressive reshoring of activities is integral to achieving its sustainability principles
Search for new physics in the multijet and missing transverse momentum final state in proton-proton collisions at √s=8 Tev
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