1,821 research outputs found
Sediment budget possibilities and improbabilities
Problems of constructing a sediment budget for an inlet is often a challenge due to constraints on data collection, quality of data, and assumptions one is willing to consider. Existing literature does not provide a systematic foundation for equations considered and often engineers and geologists typically do not properly consider the mathematical constraints placed on the problem of sediment budget construction. The present technical note presents a simple methodology for assessing sediment budget, i.e. what is possible, and what is not possible via a matrix equation system and linear algebra. It is hoped that engineers and geologists will not impose unrealistic expectations on the sediment budget system via using such an approach. Some simple examples are given of both pitfalls and correct approaches to sediment budget development
Hybrid Rules with Well-Founded Semantics
A general framework is proposed for integration of rules and external first
order theories. It is based on the well-founded semantics of normal logic
programs and inspired by ideas of Constraint Logic Programming (CLP) and
constructive negation for logic programs. Hybrid rules are normal clauses
extended with constraints in the bodies; constraints are certain formulae in
the language of the external theory. A hybrid program is a pair of a set of
hybrid rules and an external theory. Instances of the framework are obtained by
specifying the class of external theories, and the class of constraints. An
example instance is integration of (non-disjunctive) Datalog with ontologies
formalized as description logics.
The paper defines a declarative semantics of hybrid programs and a
goal-driven formal operational semantics. The latter can be seen as a
generalization of SLS-resolution. It provides a basis for hybrid
implementations combining Prolog with constraint solvers. Soundness of the
operational semantics is proven. Sufficient conditions for decidability of the
declarative semantics, and for completeness of the operational semantics are
given
Identification of type III hyperlipoproteinemia by electrophoresis on cellulose acetate and indirect (Schiff's) staining
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/32788/1/0000161.pd
Towards sustainability in European agricultural firms
Agricultural activity plays an important role in all 28 Member States (MS) of the European Union (EU) in terms of:
-Economics,
-Environmental,
-Social, and
-Political activity.
The sector also provides:
-agricultural goods and services to support food security;
-exports and imports at European and World level;
-creation of direct and indirect jobs; and
-the maintenance of population living in rural and regional areas.N/
Catalytic enantioselective syn hydration of enones in water using a DNA-based catalyst
The enantioselective addition of water to olefins in an aqueous environment is a common transformation in biological systems, but was beyond the ability of synthetic chemists. Here, we present the first examples of a non-enzymatic catalytic enantioselective hydration of enones, for which we used a catalyst that comprises a copper complex, based on an achiral ligand, non-covalently bound to (deoxy)ribonucleic acid, which is the only source of chirality present under the reaction conditions. The chiral β-hydroxy ketone product was obtained in up to 82% enantiomeric excess. Deuterium-labelling studies demonstrated that the reaction is diastereospecific, with only the syn hydration product formed. So far, this diastereospecific and enantioselective reaction had no equivalent in conventional homogeneous catalysis
The Luminosity Function of Early-Type Galaxies at z~0.75
We measure the luminosity function of morphologically selected E/S0 galaxies
from to using deep high resolution Advanced Camera for Surveys
imaging data. Our analysis covers an area of 48\Box\arcmin (8 the
area of the HDF-N) and extends 2 magnitudes deeper ( mag) than was
possible in the Deep Groth Strip Survey (DGSS). At , we find
and , and at
, we find . These luminosity
functions are similar in both shape and number density to the luminosity
function using morphological selection (e.g., DGSS), but are much steeper than
the luminosity functions of samples selected using morphological proxies like
the color or spectral energy distribution (e.g., CFRS, CADIS, or COMBO-17). The
difference is due to the `blue', , E/S0 galaxies, which make up to
of the sample at all magnitudes and an increasing proportion of faint
galaxies. We thereby demonstrate the need for {\it both morphological and
structural information} to constrain the evolution of galaxies.
We find that the `blue' E/S0 galaxies have the same average sizes and Sersic
parameters as the `red', , E/S0 galaxies at brighter luminosities
(), but are increasingly different at fainter magnitudes where
`blue' galaxies are both smaller and have lower Sersic parameters. Fits of the
colors to stellar population models suggest that most E/S0 galaxies have short
star-formation time scales ( Gyr), and that galaxies have formed at an
increasing rate from until after which there has been a
gradual decline.Comment: 39 pages, 21 figures, accepted in A
Evaluation of rK39 rapid diagnostic tests for canine visceral leishmaniasis : longitudinal study and meta-analysis
Canine visceral leishmaniasis is a vector-borne disease caused by the intracellular parasite Leishmania infantum. It is an important veterinary disease, and dogs are also the main animal reservoir for human infection. The disease is widespread in the Mediterranean area, and parts of Asia and South and Central America, and is potentially fatal in both dogs and humans unless treated. Diagnosis of canine infections requires serological or molecular tests. Detection of infection in dogs is important prior to treatment, and in epidemiological studies and control programmes, and a sensitive and specific rapid diagnostic test would be very useful. Rapid diagnostic tests (RDTs) have been developed, but their diagnostic performance has been reported to be variable. We evaluated the sensitivity of a RDT based on serological detection of the rK39 antigen in a cohort of naturally infected Brazilian dogs. The sensitivity of the test to detect infection was relatively low, but increased with time since infection and the severity of infection. We then carried out a meta-analysis of published studies of rK39 RDTs, evaluating the sensitivity to detect disease and infection. The results suggest that rK39 RDTs may be useful in a veterinary clinical setting, but the sensitivity to detect infection is too low for operational control programmes
Effects of intrauterine exposure to synthetic glucocorticoids on fetal, newborn, and infant hypothalamic-pituitary-adrenal axis function in humans : a systematic review
BACKGROUND: Synthetic glucocorticoids are commonly used in reproductive medicine. Fetal organ systems are highly sensitive to changes in the intrauterine environment, including overexposure to glucocorticoids. Structural and functional alterations resulting from such changes may persist throughout life and have been associated with diverse diseases. One system that could be particularly sensitive to fetal glucocorticoid overexposure is the hypothalamic-pituitary-adrenal (hpa) axis. Many human studies have investigated this possibility, but a systematic review to identify consistent, emergent findings is lacking. METHODS: We systematically review 49 human studies, assessing the effects of intrauterine exposure to synthetic glucocorticoids on fetal, neonate, and infant hpa function. RESULTS: Study quality varied considerably, but the main findings held true after restricting the analyses to higher-quality studies: intrauterine exposure to synthetic glucocorticoids reduces offspring hpa activity under unstimulated conditions after pain but not pharmacological challenge. Although reduced unstimulated hpa function appears to recover within the first 2 wk postpartum, blunted hpa reactivity to pain is likely to persist throughout the first 4 months of life. There is some evidence that the magnitude of the effects is correlated with the total amount of glucocorticoids administered and varies with the time interval between glucocorticoid exposure and hpa assessment. CONCLUSIONS: This systematic review has allowed the demonstration of the way in which intrauterine exposure to various regimens of synthetic glucocorticoids affects various forms of hpa function. As such, it guides future studies in terms of which variables need to be focused on in order to further strengthen the understanding of such therapy, whilst continuing to profit from its clinical benefits
How do African grey parrots (Psittacus erithacus) perform on a delay of gratification task?
Humans and other animals often find it difficult to choose a delayed reward over an immediate one, even when the delay leads to increased pay-offs. Using a visible incremental reward procedure, we tested the ability of three grey parrots to maintain delay of gratification for an increasingly valuable food pay-off. Up to 5 sunflower seeds were placed within the parrot’s reach, one at a time, at a rate of 1 seed per second. When the parrot took a seed the trial was ended and the birds consumed the accumulated seeds. Parrots were first tested in daily sessions of 10 trials and then with single daily trials. For multiple trial sessions, all three parrots showed some limited improvement across 30 sessions. For single trial sessions, only one parrot showed any increase in seed acquisition across trials. This parrot was also able to consistently obtain two or more seeds per trial (across both multiple and single trial conditions) but was unable to able to wait 5 seconds to obtain the maximum number of seeds. This parrot was also tested on a slower rate of seed presentation, and this significantly reduced her mean seed acquisition in both multiple and single trial conditions, suggesting that both value of reward available and delay duration impact upon self-control. Further manipulation of both the visibility and proximity of seeds during delay maintenance had little impact upon tolerance of delays for both parrots tested in this condition. This task demanded not just a choice of delayed reward but the maintenance of delayed gratification and was clearly difficult for the parrots to learn; additional training or alternative paradigms are required to better understand the capacity for self-control in this species
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