1,428 research outputs found
Stability and Antioxidant Activity of Hydro-Glyceric Extracts Obtained from Different Grape Seed Varieties Incorporated in Cosmetic Creams
Grape seeds are agro-industrial by-products, which if improperly managed, may be responsible for socioeconomic and environmental problems. Nevertheless, it is possible to effectively valorize them by means of extraction of the bioactive compounds, especially the antioxidant phenolic molecules, using a safe, green, and environmentally-friendly extractive medium (i.e., hydro-glyceric solution). In the present study, the extraction was performed using seeds from two Lebanese varieties, Obeidi and Asswad Karech, and three international varieties, Marselan, Syrah, and Cabernet Franc. The type and amount of phenolic compounds were identified by High-Performance Liquid Chromatography (HPLC). Marselan was the extract richer in catechins (132.99 +/- 9.81 mu g/g of dried matter), and it also contained a higher amount of phenolic compounds (49.08 +/- 0.03 mg of gallic acid equivalent/g of dry matter and 10.02 +/- 0.24 mg of proanthocyanidin content/g of dry matter). The antioxidant capacity of the extracts was assessed using three different colorimetric assays including 2,2-DiPhenyl-1-PicrylHydrazyl (DPPH), CUPRIC ion Reducing Antioxidant Capacity (CUPRAC), and Ferric Reducing Antioxidant Power (FRAP). As expected, Marselan exhibited the highest antioxidant activity; as well, the total phenolic and proanthocyanidin content were the highest. The stability of the Marselan extract incorporated into a commercial cream, was performed at three different temperatures (4, 25, and 50 degrees C), and four different concentrations (5, 4, 3, 2%), over a period of 4 months, using different methods such as centrifugation, Heat-Shock Cycles, pH, and viscosity. All Marselan hydro-glyceric extract formulations were proven to be stable over the entire 4 months, where the highest stability was achieved at 4 degrees C and the least at 50 degrees C. This study supports the suitability of the incorporation of phenolic extracts into commercial creams to enrich the cosmetic industry with effective, natural, and safe skincare products
Valorization of wine‐making by‐products’ extracts in cosmetics
The increased demand for conscious, sustainable and beneficial products by the consumers has pushed researchers from both industries and universities worldwide to search for smart strategies capable of reducing the environmental footprint, especially the ones connected with industrial wastes. Among various by-products, generally considered as waste, those obtained by winemaking industries have attracted the attention of a wide variety of companies, other than the vineries. In particular, grape pomaces are considered of interest due to their high content in bioactive molecules, especially phenolic compounds. The latter can be recovered from grape pomace and used as active ingredients in easily marketable cosmetic products. Indeed, phenolic compounds are well known for their remarkable beneficial properties at the skin level, such as antioxidant, antiaging, anti-hyperpigmentation and photoprotective effects. The exploitation of the bioactives contained in grape pomaces to obtain high value cosmetics may support the growing of innovative start-ups and expand the value chain of grapes. This review aims to describe the strategies for recovery of polyphenols from grape pomace, to highlight the beneficial potential of these extracts, both in vitro and in vivo, and their potential utilization as active ingredients in cosmetic products
Subgap anomaly and above-energy-gap structure in chains of diffusive SNS junctions
We present the results of low-temperature transport measurements on chains of
superconductor--normal-constriction--superconductor (SNS) junctions fabricated
on the basis of superconducting PtSi film. A comparative study of the
properties of the chains, consisting of 3 and 20 SNS junctions in series, and
single SNS junctions reveals essential distinctions in the behavior of the
current-voltage characteristics of the systems: (i) the gradual decrease of the
effective suppression voltage for the excess conductivity observed at zero bias
as the quantity of the SNS junctions increases, (ii) a rich fine structure on
the dependences dV/dI-V at dc bias voltages higher than the superconducting gap
and corresponding to some multiples of 2\Delta/e. A model to explain this
above-energy-gap structure based on energy relaxation of electron via
Cooper-pair-breaking in superconducting island connecting normal metal
electrods is proposed.Comment: RevTex, 5 pages, 4 figure
Two-dimensional array of diffusive SNS junctions with high-transparent interfaces
We report the first comparative study of the properties of two-dimensional
arrays and single superconducting film - normal wire - superconducting film
(SNS) junctions. The NS interfaces of our SNS junctions are really high
transparent, for superconducting and normal metal parts are made from the same
material (superconducting polycrystalline PtSi film). We have found that the
two-dimensional arrays reveal some novel features: (i) the significant
narrowing of the zero bias anomaly (ZBA) in comparison with single SNS
junctions, (ii) the appearance of subharmonic energy gap structure (SGS), with
up to n=16 (eV=\pm 2\Delta/n), with some numbers being lost, (iii) the
transition from 2D logarithmic weak localization behavior to metallic one. Our
experiments show that coherent phenomena governed by the Andreev reflection are
not only maintained over the macroscopic scale but manifest novel pronounced
effects as well. The behavior of the ZBA and SGS in 2D array of SNS junctions
strongly suggests that the development of a novel theoretical approach is
needed which would self-consistently take into account the distribution of the
currents, the potentials, and the superconducting order parameter.Comment: RevTex, 5 pages, 5 figure
Full Current Statistics in Diffusive Normal-Superconductor Structures
We study the current statistics in normal diffusive conductors in contact
with a superconductor. Using an extension of the Keldysh Green's function
method we are able to find the full distribution of charge transfers for all
temperatures and voltages. For the non-Gaussian regime, we show that the
equilibrium current fluctuations are enhanced by the presence of the
superconductor. We predict an enhancement of the nonequilibrium current noise
for temperatures below and voltages of the order of the Thouless energy
E_Th=D/L^2. Our calculation fully accounts for the proximity effect in the
normal metal and agrees with experimental data. We demonstrate that the
calculation of the full current statistics is in fact simpler than a concrete
calculation of the noise.Comment: 4 pages, 2 figures (included
Coherent low-energy charge transport in a diffusive S-N-S junction
We have studied the current voltage characteristics of diffusive mesoscopic
Nb-Cu-Nb Josephson junctions with highly-transparent Nb-Cu interfaces. We
consider the low-voltage and high-temperature regime eV<\epsilon_{c}<k_{B}T
where epsilon_{c} is the Thouless energy. The observed excess current as well
as the observed sub-harmonic Shapiro steps under microwave irradiation suggest
the occurrence of low-energy coherent Multiple Andreev Reflection (MAR).Comment: 4 pages, 4 figures, final versio
Complete Mitochondrial Genome and Phylogeny of Pleistocene MammothMammuthus primigenius
Phylogenetic relationships between the extinct woolly mammoth(Mammuthus primigenius), and the Asian(Elephas maximus) and African savanna(Loxodonta africana) elephants remain unresolved. Here, we report the sequence of the complete mitochondrial genome (16,842 base pairs) of a woolly mammoth extracted from permafrost-preserved remains from the Pleistocene epoch—the oldest mitochondrial genome sequence determined to date. We demonstrate that well-preserved mitochondrial genome fragments, as long as ~1,600–1700 base pairs, can be retrieved from pre-Holocene remains of an extinct species. Phylogenetic reconstruction of the Elephantinae clade suggests thatM. primigenius andE. maximus are sister species that diverged soon after their common ancestor split from theL. africana lineage. Low nucleotide diversity found between independently determined mitochondrial genomic sequences of woolly mammoths separated geographically and in time suggests that north-eastern Siberia was occupied by a relatively homogeneous population ofM. primigenius throughout the late Pleistocene
Search for new physics with dijet angular distributions in proton-proton collisions at root S = 13 TeV
Peer reviewe
Search for narrow resonances in dilepton mass spectra in proton-proton collisions at root s=13 TeV and combination with 8 TeV data
Peer reviewe
Search for light bosons in decays of the 125 GeV Higgs boson in proton-proton collisions at root s=8 TeV
Peer reviewe
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