Skin cancers are the most frequent cancers in fair-skinned populations, but we can prevent them

: Cancers of the skin are the most commonly occurring cancers in humans. In fair-skinned populations, up to 95% of keratinocyte skin cancers and 70-95% of cutaneous melanomas are caused by ultraviolet radiation and are thus theoretically preventable. Currently, however, there is no comprehensive global advice on practical steps to be taken to reduce the toll of skin cancer. To address this gap, an expert working group comprising clinicians and researchers from Africa, America, Asia, Australia, and Europe, together with learned societies (European Association of Dermato-Oncology, Euromelanoma, Euroskin, European Union of Medical Specialists, and the Melanoma World Society) reviewed the extant evidence and issued the following evidence-based recommendations for photoprotection as a strategy to prevent skin cancer. Fair skinned people, especially children, should minimise their exposure to ultraviolet radiation, and are advised to use protective measures when the UV index is forecast to reach 3 or higher. Protective measures include a combination of seeking shade, physical protection (e.g. clothing, hat, sunglasses), and applying broad-spectrum, SPF 30 + sunscreens to uncovered skin. Intentional exposure to solar ultraviolet radiation for the purpose of sunbathing and tanning is considered an unhealthy behaviour and should be avoided. Similarly, use of solaria and other artificial sources of ultraviolet radiation to encourage tanning should be strongly discouraged, through regulation if necessary. Primary prevention of skin cancer has a positive return on investment. We encourage policymakers to communicate these messages to the general public and promote their wider implementation

Psychometric Properties and Correlates of Precarious Manhood Beliefs in 62 Nations

Precarious manhood beliefs portray manhood, relative to womanhood, as a social status that is hard to earn, easy to lose, and proven via public action. Here, we present cross-cultural data on a brief measure of precarious manhood beliefs (the Precarious Manhood Beliefs scale [PMB]) that covaries meaningfully with other cross-culturally validated gender ideologies and with country-level indices of gender equality and human development. Using data from university samples in 62 countries across 13 world regions (N = 33,417), we demonstrate: (1) the psychometric isomorphism of the PMB (i.e., its comparability in meaning and statistical properties across the individual and country levels); (2) the PMB’s distinctness from, and associations with, ambivalent sexism and ambivalence toward men; and (3) associations of the PMB with nation-level gender equality and human development. Findings are discussed in terms of their statistical and theoretical implications for understanding widely-held beliefs about the precariousness of the male gender role

Congenital dystrophy-like myopathy in a Brittany Spaniel puppy

A congenital myopathy is reported in the only male puppy from a litter of Brittany Spaniels. The condition was manifested clinically as generalized weakness, mild generalized muscle atrophy and difficulty in eating due to tongue muscle hypertrophy. Creatine kinase values were extremely high. Electromyographically, there were complex repetitive discharges that persisted (pseudomyotonia). Histopathologic examination revealed muscle fiber degeneration, size variation, hyalinization, mineralization, necrosis, and regeneration. Clinical signs, serum biochemistry, electrophysiological and pathological findings of this myopathy have much in common with the canine X-linked muscular dystrophies and with Duchenne muscular dystrophy in humans

Project management and institutional repositories : a case study at University College Dublin Library

This paper describes University College Dublin Library's participation in a series of parallel projects including building a national open access portal, Rian.ie; developing an international subject based portal, EconomistsOnline.org; and the planning, development and management of a university institutional repository (IR) service. Particular emphasis is placed on the use of the PMBOK® project management methodology. While much of the literature on IRs concentrates on critical success factors, only a few papers suggest applying standard methodologies to IR project planning, and very few papers detail the complex process of planning an IR using these methodologies. This paper addresses this gap in the literature and describes the practical experience of participating in two OAI-PMH harvesting projects at national and international levels and the effect that this has had on local IR development. Participating in the two services can be shown to have had a positive effect on all aspects of project management.Not applicableEmail from publisher confirms - Because this issue will be published online only as open access there will be no embargo period. TS 18.11.1