Comparison of two methods of teaching word meaning through the use of word parts in grades ten, eleven, and twelve

Thesis (Ed.D.)--Boston University

Word service for grades one through six

Thesis (Ed.M.)--Boston Universit

Twenty-One Days of Lunar Environment Alters Muscle Fiber Areas in Mouse Gastrocnemius

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VII. Discours

Introduction: Progress in understanding and management of vascular cognitive impairment (VCI) has been hampered by lack of consensus on diagnosis, reflecting the use of multiple different assessment protocols. A large multinational group of clinicians and researchers participated in a two-phase Vascular Impairment of Cognition Classification Consensus Study (VICCCS) to agree on principles (VICCCS-1) and protocols (VICCCS-2) for diagnosis of VCI. We present VICCCS-2. Methods: We used VICCCS-1 principles and published diagnostic guidelines as points of reference for an online Delphi survey aimed at achieving consensus on clinical diagnosis of VCI. Results: Six survey rounds comprising 65–79 participants agreed guidelines for diagnosis of VICCCS-revised mild and major forms of VCI and endorsed the National Institute of Neurological Disorders–Canadian Stroke Network neuropsychological assessment protocols and recommendations for imaging. Discussion: The VICCCS-2 suggests standardized use of the National Institute of Neurological Disorders–Canadian Stroke Network recommendations on neuropsychological and imaging assessment for diagnosis of VCI so as to promote research collaboration

Progress toward standardized diagnosis of vascular cognitive impairment: Guidelines from the Vascular Impairment of Cognition Classification Consensus Study

INTRODUCTION: Progress in understanding and management of vascular cognitive impairment (VCI) has been hampered by lack of consensus on diagnosis, reflecting the use of multiple different assessment protocols. A large multinational group of clinicians and researchers participated in a two-phase Vascular Impairment of Cognition Classification Consensus Study (VICCCS) to agree on principles (VICCCS-1) and protocols (VICCCS-2) for diagnosis of VCI. We present VICCCS-2. METHODS: We used VICCCS-1 principles and published diagnostic guidelines as points of reference for an online Delphi survey aimed at achieving consensus on clinical diagnosis of VCI. RESULTS: Six survey rounds comprising 65-79 participants agreed guidelines for diagnosis of VICCCS-revised mild and major forms of VCI and endorsed the National Institute of Neurological Disorders-Canadian Stroke Network neuropsychological assessment protocols and recommendations for imaging. DISCUSSION: The VICCCS-2 suggests standardized use of the National Institute of Neurological Disorders-Canadian Stroke Network recommendations on neuropsychological and imaging assessment for diagnosis of VCI so as to promote research collaboration

Mortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection: an international cohort study

Background: The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on postoperative recovery needs to be understood to inform clinical decision making during and after the COVID-19 pandemic. This study reports 30-day mortality and pulmonary complication rates in patients with perioperative SARS-CoV-2 infection. Methods: This international, multicentre, cohort study at 235 hospitals in 24 countries included all patients undergoing surgery who had SARS-CoV-2 infection confirmed within 7 days before or 30 days after surgery. The primary outcome measure was 30-day postoperative mortality and was assessed in all enrolled patients. The main secondary outcome measure was pulmonary complications, defined as pneumonia, acute respiratory distress syndrome, or unexpected postoperative ventilation. Findings: This analysis includes 1128 patients who had surgery between Jan 1 and March 31, 2020, of whom 835 (74·0%) had emergency surgery and 280 (24·8%) had elective surgery. SARS-CoV-2 infection was confirmed preoperatively in 294 (26·1%) patients. 30-day mortality was 23·8% (268 of 1128). Pulmonary complications occurred in 577 (51·2%) of 1128 patients; 30-day mortality in these patients was 38·0% (219 of 577), accounting for 81·7% (219 of 268) of all deaths. In adjusted analyses, 30-day mortality was associated with male sex (odds ratio 1·75 [95% CI 1·28–2·40], p\textless0·0001), age 70 years or older versus younger than 70 years (2·30 [1·65–3·22], p\textless0·0001), American Society of Anesthesiologists grades 3–5 versus grades 1–2 (2·35 [1·57–3·53], p\textless0·0001), malignant versus benign or obstetric diagnosis (1·55 [1·01–2·39], p=0·046), emergency versus elective surgery (1·67 [1·06–2·63], p=0·026), and major versus minor surgery (1·52 [1·01–2·31], p=0·047). Interpretation: Postoperative pulmonary complications occur in half of patients with perioperative SARS-CoV-2 infection and are associated with high mortality. Thresholds for surgery during the COVID-19 pandemic should be higher than during normal practice, particularly in men aged 70 years and older. Consideration should be given for postponing non-urgent procedures and promoting non-operative treatment to delay or avoid the need for surgery. Funding: National Institute for Health Research (NIHR), Association of Coloproctology of Great Britain and Ireland, Bowel and Cancer Research, Bowel Disease Research Foundation, Association of Upper Gastrointestinal Surgeons, British Association of Surgical Oncology, British Gynaecological Cancer Society, European Society of Coloproctology, NIHR Academy, Sarcoma UK, Vascular Society for Great Britain and Ireland, and Yorkshire Cancer Research

Progress toward standardized diagnosis of vascular cognitive impairment : guidelines from the vascular impairment of cognition classification consensus study

Introduction: Progress in understanding and management of vascular cognitive impairment (VCI) has been hampered by lack of consensus on diagnosis, reflecting the use of multiple different assessment protocols. A large multinational group of clinicians and researchers participated in a two-phase Vascular Impairment of Cognition Classification Consensus Study (VICCCS) to agree on principles (VICCCS-1) and protocols (VICCCS-2) for diagnosis of VCI. We present VICCCS-2. Methods: We used VICCCS-1 principles and published diagnostic guidelines as points of reference for an online Delphi survey aimed at achieving consensus on clinical diagnosis of VCI. Results: Six survey rounds comprising 65-79 participants agreed guidelines for diagnosis of VICCCS-revised mild and major forms of VCI and endorsed the National Institute of Neurological Disorders-Canadian Stroke Network neuropsychological assessment protocols and recommendations for imaging. Discussion: The VICCCS-2 suggests standardized use of the National Institute of Neurological Disorders-Canadian Stroke Network recommendations on neuropsychological and imaging assessment for diagnosis of VCI so as to promote research collaboration. (C) 2017 the Alzheimer's Association. Published by Elsevier Inc. All rights reserved.Alzheimer's Society (UK)PfizerAthersysAstraZenecaLundbeckCerevastDaiichi SankyoBoehringer IngelheimGE HealthcareTauRxCytoxAvid/LillyTakedaEli LillyElan/Transition TherapeuticsRocheCognoptixEisaiNovartisUniv Bristol, Translat Hlth Sci, Bristol, Avon, EnglandUniv Toronto, Sunnybrook Res Inst, Toronto, ON, CanadaNatl Univ Singapore, Dept Pharmacol, Singapore, SingaporeUniv Calif Davis, Dept Neurol, Sacramento, CA 95817 USAUniv Calif Davis, Ctr Neurosci, Sacramento, CA 95817 USAUniv Helsinki, Neurol, Helsinki, FinlandHelsinki Univ Hosp, Helsinki, FinlandUniv Oxford, Div Med Sci, Oxford, EnglandNewcastle Univ, Inst Neurosci, Newcastle, EnglandUniv Cambridge, Sch Clin Med, Dept Psychiat, Cambridge, EnglandUniv Florence, NEUROFARBA Dept, Florence, ItalyUniv Lille, INSERM, U1171, Lille, FranceMethodist Neurol Inst, Houston, TX USASahlgrens Univ Hosp, Memory Clin, Dept Neuropsychiat, Molndal, SwedenUniv Gothenburg, Sahlgrenska Acad, Inst Neurosci & Physiol, Gothenburg, SwedenUniv New South Wales, Sch Psychiat, Sydney, NSW, AustraliaPrince Wales Hosp, Neuropsychiat Inst, Randwick, NSW, AustraliaUniv Bristol, Populat Hlth Sci, Bristol, Avon, EnglandQueens Univ Belfast, Inst Clin Sci, Block B, Belfast, Antrim, North IrelandCONICET Natl Res Council, Buenos Aires, DF, ArgentinaCEMIC Univ Hosp, Buenos Aires, DF, ArgentinaUniv Sydney, Sydney, AustraliaMed Univ Graz, Graz, AustriaInst Clin Neurobiol, Graz, AustriaMed Univ Vienna, Graz, AustriaUniv Antwerp, Antwerp, BelgiumRevArte Rehabil Hosp, Antwerp, BelgiumCathol Univ Leuven, Leuven, BelgiumUniv Fed Sao Paulo, Sao Paulo, BrazilUniv Sao Paulo, Sao Paulo, BrazilUniv Fed Minas Gerais, Belo Horizonte, MG, BrazilDept Psychiat Sao Paulo Med Sch, Sao Paulo, BrazilUniv Sherbrooke, Sherbrooke, PQ, CanadaUniv Calgary, Calgary, AB, CanadaUniv British Columbia, Vancouver, BC, CanadaUniv Saskatchewan, Saskatoon, SK, CanadaYork Univ, Glendon Coll, York, N Yorkshire, EnglandHop Maisonneuve, Montreal, PQ, CanadaMcMaster Univ, Hamilton, ON, CanadaFudan Univ, Huashan Hosp, Shanghai, Peoples R ChinaBeijing Univ Chinese Med, Dongzhimen Hosp, Beijing, Peoples R ChinaUniv Fed Sao Paulo, Sao Paulo, BrazilASUK: Ref117Web of Scienc

From ‘politics of numbers’ to ‘politics of singularisation’:Patients’ activism and engagement in research on rare diseases in France and Portugal

This article investigates how the engagement of patients/' organisations (POs) in research relates to the dynamics of their activism in the area of rare diseases. It traces back how certain concerned families and groups elaborated rareness as an issue of equity and social justice, gave shape to what we call a /`politics of numbers/' for stating the fact of rare diseases as a major public health problem, and promoted patients/' critical involvement in biomedical and therapeutic research as a solution for mainstreaming rare diseases in regular health systems. It then studies three Portuguese and three French POs, which point to the limits of the epidemiological notion of rareness for capturing the compounded and intersecting nature of the bio-psycho-social make-up of their conditions. It finally shows how these critics progressively lead to the emergence of an alternative politics, which we call a /`politics of singularisation/'. At the core of this politics stands a collective and ongoing profiling of conditions and patients, whose similarities and differences relates to the ubiquity of biological pathways and diseases categories. Our contention is that this /`politics of singularisation/' not only pictures a politics of illnesses which questions the rationale for nosological classifications, but also, and consequently, affects the making of social links by suggesting the simultaneous identification of individual patients and constitution of collectives to which they partake while asserting their specificities

The Vascular Impairment of Cognition Classification Consensus Study

Introduction Numerous diagnostic criteria have tried to tackle the variability in clinical manifestations and problematic diagnosis of vascular cognitive impairment (VCI) but none have been universally accepted. These criteria have not been readily comparable, impacting on clinical diagnosis rates and in turn prevalence estimates, research, and treatment.  Methods The Vascular Impairment of Cognition Classification Consensus Study (VICCCS) involved participants (81% academic researchers) from 27 countries in an online Delphi consensus study. Participants reviewed previously proposed concepts to develop new guidelines.  Results VICCCS had a mean of 122 (98–153) respondents across the study and a 67% threshold to represent consensus. VICCCS redefined VCI including classification of mild and major forms of VCI and subtypes. It proposes new standardized VCI-associated terminology and future research priorities to address gaps in current knowledge.  Discussion VICCCS proposes a consensus-based updated conceptualization of VCI intended to facilitate standardization in research