201 research outputs found

    Dissociable Effects of Reward on Attentional Learning: From Passive Associations to Active Monitoring

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    Visual selective attention (VSA) is the cognitive function that regulates ongoing processing of retinal input in order for selected representations to gain privileged access to perceptual awareness and guide behavior, facilitating analysis of currently relevant information while suppressing the less relevant input. Recent findings indicate that the deployment of VSA is shaped according to past outcomes. Targets whose selection has led to rewarding outcomes become relatively easier to select in the future, and distracters that have been ignored with higher gains are more easily discarded. Although outcomes (monetary rewards) were completely predetermined in our prior studies, participants were told that higher rewards would follow more efficient responses. In a new experiment we have eliminated the illusory link between performance and outcomes by informing subjects that rewards were randomly assigned. This trivial yet crucial manipulation led to strikingly different results. Items that were associated more frequently with higher gains became more difficult to ignore, regardless of the role (target or distracter) they played when differential rewards were delivered. Therefore, VSA is shaped by two distinct reward-related learning mechanisms: one requiring active monitoring of performance and outcome, and a second one detecting the sheer association between objects in the environment (whether attended or ignored) and the more-or-less rewarding events that accompany them

    Integrated CdTe PV glazing into windows: energy and daylight performance for different window-to-wall ratio

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    When integrated photovoltaics into building windows, the solar cells will absorb a fraction of solar radiation that hit on the window surface to generate electrical power and thus obstruct the solar energy and natural daylight that would have penetrated into inside space. In this paper, a window system integrated with thin film CdTe solar cells with 10% transparency was electrically characterised by Sandia model. The annual energy performance of a typical office with this PV window applied to different façade design was investigated using EnergyPlus under five typical climatic conditions in China. The dynamic daylight performance of the office has been assessed using RADIANCE. The result shows that when compared to a conventional double glazed system, the application of PV window can result in significant energy saving potential if the office has a relative large window-to-wall ratio (i.e. WWR≥45%). The simulation results also show that this PV window offers better daylight performance than conventional double-glazing

    Overshadowing depends on cue and reinforcement sensitivity but not schizotypy

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    There is evidence for impaired selective learning mechanisms in individuals high in schizotypy. Overshadowing provides a direct test of selective learning based on cue salience and has previously been reported to be impaired in relation to schizotypy scores. The present study tested for overshadowing using food allergy and Lego construction task variants. Both variants used the same number of conditioned stimulus (CS) cues and the same number of learning trials. CS cues were trained in compound pairs or in isolation and overshadowing was subsequently tested on trials followed by negative versus positive outcomes. Participants also completed the O-LIFE to measure schizotypy and BIS-BAS scales to measure reinforcement sensitivity. Learning was demonstrated for both cue variants; however overshadowing emerged only in the Lego variant and only on the trials followed by the negative outcome. Contrary to expectations, there was no evidence for any relationship between overshadowing and O-LIFE scores. However, there was evidence of a positive relationship between overshadowing and BAS-Drive as well as a negative relationship with BIS-Anxiety, for the trials followed by the positive outcome in the food allergy variant. These results suggest that the development of overshadowing depends on cue and reinforcement sensitivity, but not necessarily on schizotypy

    Thermally Induced Nano-Structural and Optical Changes of nc-Si:H Deposited by Hot-Wire CVD

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    We report on the thermally induced changes of the nano-structural and optical properties of hydrogenated nanocrystalline silicon in the temperature range 200–700 °C. The as-deposited sample has a high crystalline volume fraction of 53% with an average crystallite size of ~3.9 nm, where 66% of the total hydrogen is bonded as ≡Si–H monohydrides on the nano-crystallite surface. A growth in the native crystallite size and crystalline volume fraction occurs at annealing temperatures ≥400 °C, where hydrogen is initially removed from the crystallite grain boundaries followed by its removal from the amorphous network. The nucleation of smaller nano-crystallites at higher temperatures accounts for the enhanced porous structure and the increase in the optical band gap and average gap

    The impact of reward and punishment on skill learning depends on task demands

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    Reward and punishment motivate behavior, but it is unclear exactly how they impact skill performance and whether the effect varies across skills. The present study investigated the effect of reward and punishment in both a sequencing skill and a motor skill context. Participants trained on either a sequencing skill (serial reaction time task) or a motor skill (force-tracking task). Skill knowledge was tested immediately after training, and again 1 hour, 24-48 hours, and 30 days after training. We found a dissociation of the effects of reward and punishment on the tasks, primarily reflecting the impact of punishment. While punishment improved serial reaction time task performance, it impaired force-tracking task performance. In contrast to prior literature, neither reward nor punishment benefitted memory retention, arguing against the common assumption that reward ubiquitously benefits skill retention. Collectively, these results suggest that punishment impacts skilled behavior more than reward in a complex, task dependent fashion

    Synaptic AMPA receptor composition in development, plasticity and disease

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    From drugs to deprivation: a Bayesian framework for understanding models of psychosis

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    Disrupting transitions : qualitatively modelling the impact of Covid-19 on UK food and mobility provision

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    The 2020 Covid-19 pandemic provides an empirical testing ground for assessing the impact of critical events on societal transitions. Such events are typically seen as exogenous to the transition process, an assumption which is investigated in this paper. Using a qualitative system dynamics modelling approach we conceptualize transition pathways as sets of interacting sequences of events. This enables the analysis of event sequences that constitute the evolving pandemic as impacting on those pathways. We apply this approach to the provision of (auto)mobility and food in the UK. This shows the way in which the pandemic has had a differential effect on ongoing transitions in both systems, sometimes slowing them down, and sometimes accelerating them. In addition, it reveals how it has established new transition pathways. The empirical work further shows how qualitative modelling with system dynamics facilitates an explicit and systematic comparative analysis of transition case studies

    Brain connectivity changes occurring following cognitive behavioural therapy for psychosis predict long-term recovery

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    Little is known about the psychobiological mechanisms of cognitive behavioural therapy for psychosis (CBTp) and which specific processes are key in predicting favourable long-term outcomes. Following theoretical models of psychosis, this proof-of-concept study investigated whether the long-term recovery path of CBTp completers can be predicted by the neural changes in threatbased social affective processing that occur during CBTp. We followed up 22 participants who had undergone a social affective processing task during functional magnetic resonance imaging along with self-report and clinician-administered symptom measures, before and after receiving CBTp. Monthly ratings of psychotic and affective symptoms were obtained retrospectively across 8 years since receiving CBTp, plus self-reported recovery at final follow-up. We investigated whether these long-term outcomes were predicted by CBTp-led changes in functional connections with dorsal prefrontal cortical and amygdala during the processing of threatening and prosocial facial affect. Although long-term psychotic symptoms were predicted by changes in prefrontal connections during prosocial facial affective processing, long-term affective symptoms were predicted by threat-related amygdalo-inferior parietal lobule connectivity. Greater increases in dorsolateral prefrontal cortex connectivity with amygdala following CBTp also predicted higher subjective ratings of recovery at long-term follow-up. These findings show that reorganisation occurring at the neural level following psychological therapy can predict the subsequent recovery path of people with psychosis across 8 years. This novel methodology shows promise for further studies with larger sample size, which are needed to better examine the sensitivity of psychobiological processes, in comparison to existing clinical measures, in predicting long-term outcomes.Wellcome Trust; Biomedical Research Centre for Mental Health at the Institute of Psychiatry, Psychology & Neuroscience, King’s College London and South London and Maudsley NHS Foundation Trust, U

    Subsea Blowout Preventer (BOP): Design, Reliability, Testing, Deployment, and Operation and Maintenance Challenges

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    Subsea blowout preventer (BOP) is a safety-related instrumented system that is used in underwater oil drilling to prevent the well to blowout. As oil and gas exploration moves into deeper waters and harsher environments, the setbacks related to reliable functioning of the BOP system and its subsystems remain a major concern for researchers and practitioners. This study aims to systematically review the current state-of-the-art and present a detailed description about some of the recently developed methodologies for through-life management of the BOP system. Challenges associated with the system design, reliability analysis, testing, deployment as well as operability and maintainability are explored, and then the areas requiring further research and development will be identified. A total of 82 documents published since 1980's are critically reviewed and classified according to two proposed frameworks. The first framework categorises the literature based on the depth of water in which the BOP systems operate, with a sub-categorization based on the Macondo disaster. The second framework categorises the literature based on the techniques applied for the reliability analysis of BOP systems, including Failure Mode and Effects Analysis (FMEA), Fault Tree Analysis (FTA), Reliability Block Diagram (RBD), Petri Net (PN), Markov modelling, Bayesian Network (BN), Monte Carlo Simulation (MCS), etc. Our review analysis reveals that the reliability analysis and testing of BOP has received the most attention in the literature, whereas the design, deployment, and operation and maintenance (O&M) of BOPs received the least
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