52 research outputs found

    Salvation: Into the Cosmos: Board Game Project Blending 4X and Eurogame Styles

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    This project is an attempt at creating a shorter and simpler 4X strategy game. To do this, the author takes elements of the Eurogame genre and combines aspects of The Settlers of Catan by Klaus Teuber and Shattered Plans by Jagex while following the requirements of the German board game award, the Spiel de Jahres. After following the traditional game design process of conceptualization, prototyping, and repeated testing, analysis, and revision, the author succeeded in creating a core foundation for such a game that also had marketing potential on its own

    Finishing the euchromatic sequence of the human genome

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    The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead

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    This is a zipped folder that contains 1) a CSV formatted file of the herbarium voucher specimens used in this study. 2) an XLSX file of the checklist that summarizes when a species was collected in the study area as well as several traits scored for the species

    Data from: The lichens and allied fungi of Mount Mitchell State Park, North Carolina: a first checklist with comprehensive keys and comparison to historical data

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    A total of 171 species of lichens and allied fungi are reported from the spruce-fir forests of Mount Mitchell State Park, in the Black Mountains of North Carolina, based on both historical and modern records. Comparison of the modern baseline with the historical macrolichen baseline generated in the 1970s revealed potential losses of high-elevation southern Appalachian endemics (2 species), cyanolichens (5 species), species typical of exposed rock outcrops (1 species), and widespread species typical of hardwood substrates at high elevations (8 species). In addition to a checklist and summary of lichen biodiversity, dichotomous keys are provided that include all reported species

    Peptidmimetica für Rezeptorliganden – Entdeckung, Entwicklung und medizinische Perspektiven

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    DUNE Offline Computing Conceptual Design Report

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    This document describes Offline Software and Computing for the Deep Underground Neutrino Experiment (DUNE) experiment, in particular, the conceptual design of the offline computing needed to accomplish its physics goals. Our emphasis in this document is the development of the computing infrastructure needed to acquire, catalog, reconstruct, simulate and analyze the data from the DUNE experiment and its prototypes. In this effort, we concentrate on developing the tools and systems thatfacilitate the development and deployment of advanced algorithms. Rather than prescribing particular algorithms, our goal is to provide resources that are flexible and accessible enough to support creative software solutions as HEP computing evolves and to provide computing that achieves the physics goals of the DUNE experiment

    DUNE Offline Computing Conceptual Design Report

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    International audienceThis document describes Offline Software and Computing for the Deep Underground Neutrino Experiment (DUNE) experiment, in particular, the conceptual design of the offline computing needed to accomplish its physics goals. Our emphasis in this document is the development of the computing infrastructure needed to acquire, catalog, reconstruct, simulate and analyze the data from the DUNE experiment and its prototypes. In this effort, we concentrate on developing the tools and systems thatfacilitate the development and deployment of advanced algorithms. Rather than prescribing particular algorithms, our goal is to provide resources that are flexible and accessible enough to support creative software solutions as HEP computing evolves and to provide computing that achieves the physics goals of the DUNE experiment

    DUNE Offline Computing Conceptual Design Report

    No full text
    This document describes Offline Software and Computing for the Deep Underground Neutrino Experiment (DUNE) experiment, in particular, the conceptual design of the offline computing needed to accomplish its physics goals. Our emphasis in this document is the development of the computing infrastructure needed to acquire, catalog, reconstruct, simulate and analyze the data from the DUNE experiment and its prototypes. In this effort, we concentrate on developing the tools and systems thatfacilitate the development and deployment of advanced algorithms. Rather than prescribing particular algorithms, our goal is to provide resources that are flexible and accessible enough to support creative software solutions as HEP computing evolves and to provide computing that achieves the physics goals of the DUNE experiment

    DUNE Offline Computing Conceptual Design Report

    No full text
    This document describes Offline Software and Computing for the Deep Underground Neutrino Experiment (DUNE) experiment, in particular, the conceptual design of the offline computing needed to accomplish its physics goals. Our emphasis in this document is the development of the computing infrastructure needed to acquire, catalog, reconstruct, simulate and analyze the data from the DUNE experiment and its prototypes. In this effort, we concentrate on developing the tools and systems thatfacilitate the development and deployment of advanced algorithms. Rather than prescribing particular algorithms, our goal is to provide resources that are flexible and accessible enough to support creative software solutions as HEP computing evolves and to provide computing that achieves the physics goals of the DUNE experiment
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