Universal Spin Transport in a Strongly Interacting Fermi Gas

Transport of fermions is central in many elds of physics. Electron transport runs modern technology, de ning states of matter such as superconductors and insulators, and electron spin, rather than charge, is being explored as a new carrier of information [1]. Neutrino transport energizes supernova explosions following the collapse of a dying star [2], and hydrodynamic transport of the quark-gluon plasma governed the expansion of the early Universe [3]. However, our understanding of non-equilibrium dynamics in such strongly interacting fermionic matter is still limited. Ultracold gases of fermionic atoms realize a pristine model for such systems and can be studied in real time with the precision of atomic physics [4, 5]. It has been established that even above the super uid transition such gases ow as an almost perfect uid with very low viscosity [3, 6] when interactions are tuned to a scattering resonance. However, here we show that spin currents, as opposed to mass currents, are maximally damped, and that interactions can be strong enough to reverse spin currents, with opposite spin components reflecting off each other. We determine the spin drag coefficient, the spin di usivity, and the spin susceptibility, as a function of temperature on resonance and show that they obey universal laws at high temperatures. At low temperatures, the spin di usivity approaches a minimum value set by ħ/m, the quantum limit of di usion, where ħ is the reduced Planck's constant and m the atomic mass. For repulsive interactions, our measurements appear to exclude a metastable ferromagnetic state [7{9].National Science Foundation (U.S.)United States. Office of Naval ResearchUnited States. Army Research Office (DARPA OLE programme)Alfred P. Sloan FoundationUnited States. Air Force Office of Scientific Research. Multidisciplinary University Research InitiativeUnited States. Army Research Office. Multidisciplinary University Research InitiativeUnited States. Defense Advanced Research Projects Agency. Young Faculty AwardDavid & Lucile Packard Foundatio

Association of Variants in the SPTLC1 Gene With Juvenile Amyotrophic Lateral Sclerosis

Importance: Juvenile amyotrophic lateral sclerosis (ALS) is a rare form of ALS characterized by age of symptom onset less than 25 years and a variable presentation.Objective: To identify the genetic variants associated with juvenile ALS.Design, Setting, and Participants: In this multicenter family-based genetic study, trio whole-exome sequencing was performed to identify the disease-associated gene in a case series of unrelated patients diagnosed with juvenile ALS and severe growth retardation. The patients and their family members were enrolled at academic hospitals and a government research facility between March 1, 2016, and March 13, 2020, and were observed until October 1, 2020. Whole-exome sequencing was also performed in a series of patients with juvenile ALS. A total of 66 patients with juvenile ALS and 6258 adult patients with ALS participated in the study. Patients were selected for the study based on their diagnosis, and all eligible participants were enrolled in the study. None of the participants had a family history of neurological disorders, suggesting de novo variants as the underlying genetic mechanism.Main Outcomes and Measures: De novo variants present only in the index case and not in unaffected family members.Results: Trio whole-exome sequencing was performed in 3 patients diagnosed with juvenile ALS and their parents. An additional 63 patients with juvenile ALS and 6258 adult patients with ALS were subsequently screened for variants in the SPTLC1 gene. De novo variants in SPTLC1 (p.Ala20Ser in 2 patients and p.Ser331Tyr in 1 patient) were identified in 3 unrelated patients diagnosed with juvenile ALS and failure to thrive. A fourth variant (p.Leu39del) was identified in a patient with juvenile ALS where parental DNA was unavailable. Variants in this gene have been previously shown to be associated with autosomal-dominant hereditary sensory autonomic neuropathy, type 1A, by disrupting an essential enzyme complex in the sphingolipid synthesis pathway.Conclusions and Relevance: These data broaden the phenotype associated with SPTLC1 and suggest that patients presenting with juvenile ALS should be screened for variants in this gene.</p

Search for dark matter produced in association with bottom or top quarks in √s = 13 TeV pp collisions with the ATLAS detector

A search for weakly interacting massive particle dark matter produced in association with bottom or top quarks is presented. Final states containing third-generation quarks and miss- ing transverse momentum are considered. The analysis uses 36.1 fb−1 of proton–proton collision data recorded by the ATLAS experiment at √s = 13 TeV in 2015 and 2016. No significant excess of events above the estimated backgrounds is observed. The results are in- terpreted in the framework of simplified models of spin-0 dark-matter mediators. For colour- neutral spin-0 mediators produced in association with top quarks and decaying into a pair of dark-matter particles, mediator masses below 50 GeV are excluded assuming a dark-matter candidate mass of 1 GeV and unitary couplings. For scalar and pseudoscalar mediators produced in association with bottom quarks, the search sets limits on the production cross- section of 300 times the predicted rate for mediators with masses between 10 and 50 GeV and assuming a dark-matter mass of 1 GeV and unitary coupling. Constraints on colour- charged scalar simplified models are also presented. Assuming a dark-matter particle mass of 35 GeV, mediator particles with mass below 1.1 TeV are excluded for couplings yielding a dark-matter relic density consistent with measurements