746 research outputs found
What kind of hepatitis
Finding one major hepatotropic virus may not be enough to identify the aetiology of liver disease when risk factors are present, particularly in patients with past or present infection with other viral agents, or chronic liver disease. The pathogenic process in these cases is often complex. In the five cases we report, acute hepatitis (initiated by halothane, cytomegalovirus or Epstein-Barr virus) preceded the reactivation of hepatitis B infection, and these events occurred in patients with chronic hepatitis C infection. Each case demonstrates how several viruses can be implicated in the development of hepatitis, either as single agents or via cross-activation of T cells. The nosography of hepatitis, therefore, and the optimum therapeutic choices, can puzzle the clinical team
The solar neutrino problem after three hundred days of data at SuperKamiokande
We present an updated analysis of the solar neutrino problem in terms of both
Mikheyev-Smirnov-Wolfenstein (MSW) and vacuum neutrino oscillations, with the
inclusion of the preliminary data collected by the SuperKamiokande experiment
during 306.3 days of operation. In particular, the observed energy spectrum of
the recoil electrons from 8B neutrino scattering is discussed in detail and is
used to constrain the mass-mixing parameter space. It is shown that: 1) the
small mixing MSW solution is preferred over the large mixing one; 2) the vacuum
oscillation solutions are strongly constrained by the energy spectrum
measurement; and 3) the detection of a possible semiannual modulation of the 8B
\nu flux due to vacuum oscillations should require at least one more year of
operation of SuperKamiokande.Comment: 15 pages (RevTeX) + 8 figures (postscript). Requires epsfig.st
Model Independent Information On Solar Neutrino Oscillations
We present the results of a Bayesian analysis of solar neutrino data in terms
of nu_e->nu_{mu,tau} oscillations, independent from the Standard Solar Model
predictions for the solar neutrino fluxes. We show that such a model
independent analysis allows to constraint the values of the neutrino mixing
parameters in limited regions around the usual SMA, LMA, LOW and VO regions.
Furthermore, there is a strong indication in favor of large neutrino mixing and
large values of Delta m^2 (LMA region). We calculate also the allowed ranges of
the neutrino fluxes and we show that they are in good agreement with the
Standard Solar Model prediction. In particular, the ratio of the 8B flux with
its Standard Solar Model prediction is constrained in the interval [0.45,1.42]
with 99.73% probability. Finally, we show that the hypothesis of no neutrino
oscillations is strongly disfavored in a model independent way with respect to
the hypothesis of neutrino oscillations.Comment: 40 pages, 20 figures. Added references and improved figure
Does Solar Physics Provide Constraints to Weakly Interacting Massive Particles?
We investigate whether present data on helioseismology and solar neutrino
fluxes may constrain WIMP--matter interactions in the range of WIMP parameters
under current exploration in WIMP searches. We find that, for a WIMP mass of 30
GeV, once the effect of the presence of WIMPs in the Sun's interior is
maximized, the squared isothermal sound speed is modified, with respect to the
standard solar model, by at most 0.4% at the Sun's center. The maximal effect
on the Boron-8 solar neutrino flux is a reduction of 4.5%. Larger masses lead
to smaller effects. These results imply that present sensitivities in the
measurements of solar properties, though greatly improved in recent years, do
not provide information or constraints on WIMP properties of relevance for dark
matter. Furthermore, we show that, when current bounds from direct WIMP
searches are taken into account, the effect induced by WIMPs with dominant
coherent interactions are drastically reduced as compared to the values quoted
above. The case of neutralinos in the minimal supersymmetric standard model is
also discussed.Comment: 31 pages, 2 tables and 9 figures, typeset with ReVTeX4. The paper may
also be found at http://www.to.infn.it/~fornengo/papers/helio.ps.gz or
through http://www.to.infn.it/astropart/index.htm
Biodegradable composite porous poly(dl-lactide-co-glycolide) scaffold supports mesenchymal stem cell differentiation and calcium phosphate deposition
In recent decades, tissue engineering strategies have been proposed for the treatment of musculoskeletal diseases and bone fractures to overcome the limitations of the traditional surgical approaches based on allografts and autografts. In this work we report the development of a composite porous poly(dl-lactide-co-glycolide) scaffold suitable for bone regeneration. Scaffolds were produced by thermal sintering of porous microparticles. Next, in order to improve cell adhesion to the scaffold and subsequent proliferation, the scaffolds were coated with the osteoconductive biopolymers chitosan and sodium alginate, in a process that exploited electrostatic interactions between the positively charged biopolymers and the negatively charged PLGA scaffold. The resulting scaffolds were characterized in terms of porosity, degradation rate, mechanical properties, biocompatibility and suitability for bone regeneration. They were found to have an overall porosity of 3c85% and a degradation half time of 3c2\u2009weeks, considered suitable to support de novo bone matrix deposition from mesenchymal stem cells. Histology confirmed the ability of the scaffold to sustain adipose-derived mesenchymal stem cell adhesion, infiltration, proliferation and osteo-differentiation. Histological staining of calcium and microanalysis confirmed the presence of calcium phosphate in the scaffold sections
Observation of Scaling Violations in Scaled Momentum Distributions at HERA
Charged particle production has been measured in deep inelastic scattering
(DIS) events over a large range of and using the ZEUS detector. The
evolution of the scaled momentum, , with in the range 10 to 1280
, has been investigated in the current fragmentation region of the Breit
frame. The results show clear evidence, in a single experiment, for scaling
violations in scaled momenta as a function of .Comment: 21 pages including 4 figures, to be published in Physics Letters B.
Two references adde
Anisotropic flow of charged hadrons, pions and (anti-)protons measured at high transverse momentum in Pb-Pb collisions at TeV
The elliptic, , triangular, , and quadrangular, , azimuthal
anisotropic flow coefficients are measured for unidentified charged particles,
pions and (anti-)protons in Pb-Pb collisions at TeV
with the ALICE detector at the Large Hadron Collider. Results obtained with the
event plane and four-particle cumulant methods are reported for the
pseudo-rapidity range at different collision centralities and as a
function of transverse momentum, , out to GeV/.
The observed non-zero elliptic and triangular flow depends only weakly on
transverse momentum for GeV/. The small dependence
of the difference between elliptic flow results obtained from the event plane
and four-particle cumulant methods suggests a common origin of flow
fluctuations up to GeV/. The magnitude of the (anti-)proton
elliptic and triangular flow is larger than that of pions out to at least
GeV/ indicating that the particle type dependence persists out
to high .Comment: 16 pages, 5 captioned figures, authors from page 11, published
version, figures at http://aliceinfo.cern.ch/ArtSubmission/node/186
Centrality dependence of charged particle production at large transverse momentum in Pb-Pb collisions at TeV
The inclusive transverse momentum () distributions of primary
charged particles are measured in the pseudo-rapidity range as a
function of event centrality in Pb-Pb collisions at
TeV with ALICE at the LHC. The data are presented in the range
GeV/ for nine centrality intervals from 70-80% to 0-5%.
The Pb-Pb spectra are presented in terms of the nuclear modification factor
using a pp reference spectrum measured at the same collision
energy. We observe that the suppression of high- particles strongly
depends on event centrality. In central collisions (0-5%) the yield is most
suppressed with at -7 GeV/. Above
GeV/, there is a significant rise in the nuclear modification
factor, which reaches for GeV/. In
peripheral collisions (70-80%), the suppression is weaker with almost independently of . The measured nuclear
modification factors are compared to other measurements and model calculations.Comment: 17 pages, 4 captioned figures, 2 tables, authors from page 12,
published version, figures at
http://aliceinfo.cern.ch/ArtSubmission/node/284
Two-pion Bose-Einstein correlations in central Pb-Pb collisions at = 2.76 TeV
The first measurement of two-pion Bose-Einstein correlations in central Pb-Pb
collisions at TeV at the Large Hadron Collider is
presented. We observe a growing trend with energy now not only for the
longitudinal and the outward but also for the sideward pion source radius. The
pion homogeneity volume and the decoupling time are significantly larger than
those measured at RHIC.Comment: 17 pages, 5 captioned figures, 1 table, authors from page 12,
published version, figures at
http://aliceinfo.cern.ch/ArtSubmission/node/388
Suppression of charged particle production at large transverse momentum in central Pb-Pb collisions at TeV
Inclusive transverse momentum spectra of primary charged particles in Pb-Pb
collisions at = 2.76 TeV have been measured by the ALICE
Collaboration at the LHC. The data are presented for central and peripheral
collisions, corresponding to 0-5% and 70-80% of the hadronic Pb-Pb cross
section. The measured charged particle spectra in and GeV/ are compared to the expectation in pp collisions at the same
, scaled by the number of underlying nucleon-nucleon
collisions. The comparison is expressed in terms of the nuclear modification
factor . The result indicates only weak medium effects ( 0.7) in peripheral collisions. In central collisions,
reaches a minimum of about 0.14 at -7GeV/ and increases
significantly at larger . The measured suppression of high- particles is stronger than that observed at lower collision energies,
indicating that a very dense medium is formed in central Pb-Pb collisions at
the LHC.Comment: 15 pages, 5 captioned figures, 3 tables, authors from page 10,
published version, figures at http://aliceinfo.cern.ch/ArtSubmission/node/98
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