149 research outputs found

    A real-time garbage collection design for embedded systems

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    Spain, Germany, and the Holocaust: Uniting Global Learning and Student Philanthropy through Transdisciplinarity

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    While the atrocities of the Holocaust have been well documented, this catastrophic event has been commonly studied through the lens of a single discipline. In a course co-taught by German and Spanish professors in conjunction with the 70th anniversary of the liberation of WWII concentration camps, advanced students of German and Spanish at Northern Kentucky University engaged with this topic by analyzing, comparing, and contrasting the German-Dutch (Anne Frank) and Spanish-French (Jorge Semprún) experience. To deepen students’ cross-collaboration, the two classes engaged in a philanthropy project called the Mayerson Student Philanthropy Project. The class received a $2,000 grant, researched and advocated for local nonprofits that addressed topics related to the Holocaust, and collectively decided on the final grant recipient. This article discusses the course structure, objectives, and outcomes of a transdisciplinary approach to literature, along with student feedback about the experience

    Differential Effects Of Cardiovascular And Resistance Exercise On Functional Mobility In Individuals With Advanced Cancer: A Randomized Trial

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    Objective: To compare the effects of resistance and cardiovascular exercise on functional mobility in individuals with advanced cancer. Design: Prospective, 2-group pretest-posttest pilot study with randomization to either resistance or cardiovascular exercise mode. Setting: Comprehensive community cancer center and a hospital-based fitness facility. Demographics: Volunteer sample of individuals with advanced cancer recruited through the cancer center, palliative care service, rehabilitation department, and a local hospice. Outcome Measures: Functional mobility was assessed using the Short Physical Performance Battery (SPPB); self-reported pain and fatigue were assessed secondarily using visual analog scales. Data were analyzed using a split plot 2x2 analysis of variance (=.05). Interventions: Ten weeks of individualized resistance or cardiovascular exercise, prescribed and monitored by oncology-trained physical therapists and exercise personnel. Results: Fifty-two patients (78.8%) completed the study: 23 (67.7%) of 34 patients in the resistance arm and 29 (90.6%) of 32 patients in the cardiovascular arm. No participant withdrew because of study adverse events. Ten-week outcomes (n=52) included a significant increase in SPPB total score (P\u3c.001), increase in gait speed (P=.001), and reduction in fatigue (P=.05). Although cardiovascular exercise participants had a modestly greater improvement in SPPB total score than resistance training participants (F1,49=4.21, P=.045), the difference was not confirmed in a subsequent intention-to-treat analysis (N=66). Conclusions: Individuals with advanced cancer appear to benefit from exercise for improving functional mobility. Neither resistance nor cardiovascular exercise appeared to have a strong differential effect on outcome.https://dune.une.edu/pt_facpost/1003/thumbnail.jp

    From in situ to ex vivo: the effect of autolysis and fixation on quantitative MRI markers for myelin

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    Ex vivo histology remains the gold standard against which MRI biophysical models, e.g. the MR g-ratio which characterises the fraction of a fibre’s diameter that is myelinated, are evaluated. The MR g-ratio model requires a measure of myelin density, for which magnetization transfer saturation (MT) has been used as a biomarker. However, changes occurring post mortem, e.g. autolysis, temperature changes and fixation, significantly alter the MRI signal. Here we investigate how these changes impact MT. We found that MT decreased post mortem but greatlyincreased upon fixation. These effects are similar to reported changes of other established MRI myelin-markers

    Erosion Dynamics of Cultivated Kelp, Saccharina latissima, and Implications for Environmental Management and Carbon Sequestration

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    A growing trend of interest for the cultivation of kelp is driven by predictions for high global demands of important commodities, which require the development of alternative supplies of natural resources. In this study the dynamics of loss of biomass from cultivated Saccharina latissima were studied from February to August 2018 at two kelp farms in Northern (69°45.26′N/019°02.18′E) and in Mid-Norway (63°42.28′N/08°52.23′E). Kelp fronds at each farm were individually followed throughout the growing season. Sectional regression was applied for conversion of measured frond lengths to estimated dry weights. The study shows that between 40 and 100% of all individuals in the studied kelp population constantly eroded slightly from their distal ends. However, until June the accumulated loss was only 8% of produced dry weight. Due to dislodgement of whole sporophytes this picture changed in July and August to heavy losses in Mid-Norway. Thus, the overall losses of kelp in terms of accumulated dry weight were only 8–13% of the gross growth until harvest in June in Mid-Norway and August in Northern Norway. Losses increased significantly in Mid-Norway during July and reached 49.4% of the annual production in August. The rates of losses were separated into specific erosion and dislodgement rates. Erosion rates over the whole experimental period for the two sites were not significantly different, while differences in dislodgement rates between farm sites proved to be highly significant. The exported annual amount of carbon was estimated on the basis of lost and measured carbon content in the tissue. From these data a scenario was built for a commercial Norwegian kelp farm growing S. latissima showing a carbon export of 63–88 g C m–2y–1. This is eight times less than has been reported from scenarios for kelp farms in China. This study confirms that optimal timing of harvest is the most important management tool for avoidance of heavy losses from kelp farms. In conclusion, an industry with early harvest will likely have a low carbon export, while a late-harvested bulk production could export four to six times as much carbon with an increased potential for carbon sequestration

    To tell or not to tell: Preference elicitation with and without emphasis on scientific uncertainty

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    Decisions about the optimal use of coastal and marine resources must be taken under high uncertainty about environmental impacts and may conflict with public perception of the risk associated with current blue growth initiatives. In a discrete choice experiment conducted in valuation workshops in five communities in Arctic Norway, we examine public preferences for various aquaculture expansion paths. Respondents prefer a smaller expansion in terms of the number of aquaculture sites compared to the planned expansion. Emphasizing scientific uncertainty regarding the negative environmental impacts of aquaculture leads to lower resistance against the planned expansion

    Per Capita Income, Market Access Costs, and Trade Volumes

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    There is strong empirical evidence that countries with lower per capita income tend to have smaller trade volumes even after controlling for aggregate income. Furthermore, poorer countries do not just trade less, but have a lower number of trading partners. In this paper, I construct and estimate a general equilibrium model of trade that captures both these features of the trade data. There are two novelties in the paper. First, I introduce an association between market access costs and countries�development levels, which can account for the effect of per capita income on trade volumes and explain many zeros in bilateral trade �ows. Secondly, I develop an estimation procedure, which allows me to estimate both variable and �fixed costs of trade. I �nd that given the estimated parameters, the model performs well in matching the data. In particular, the predicted trade elasticity with respect to income per capita is close to that in the data

    Data and methods to calculate cut-off values for serum potassium and core temperature at hospital admission for extracorporeal rewarming of avalanche victims in cardiac arrest.

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    The data and estimation methods presented in this article are associated with the research article, "Cut-off values of serum potassium and core temperature at hospital admission for extracorporeal rewarming of avalanche victims in cardiac arrest: a retrospective multi-centre study" [1]. In this article we estimate recommended cut-off values for in-hospital triage with respect to extracorporeal rewarming. With only 6 survivors of 103 patients collected over a period of 20 years the ability to estimate reliable threshold values is limited. In addition, because the number of avalanche victims is also limited, a significantly larger dataset is unlikely to be obtained. We have therefore adapted two non-parametric estimation methods (bootstrapping and exact binomial distribution) to our specific needs and performed a simulations to confirm validity and reliability

    Demand-Driven Structural Change in Applied General Equilibrium Models

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    This chapter analyzes the variations in industrial structure induced by income-sensitive patterns of final consumption, and how these changes can be captured by a multi-sector numerical model with a flexible demand system. We focus, in particular, on the estimation of parameters for an AIDADS (An Implicitly, Directly Additive Demand System) specification. We then test the latter by inserting it in the ENVISAGE global general equilibrium dynamic model, which is run under the SSP2 scenario from 2011 to 2050. It is found that time-varying income elasticity can generate sizable variations in the industrial structure. This finding has important practical implications, particularly when structural models are applied at a medium and long term horizon

    Postoperative pain management in children: Guidance from the pain committee of the European Society for Paediatric Anaesthesiology (ESPA Pain Management Ladder Initiative)

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    The main remit of the European Society for Paediatric Anaesthesiology (ESPA) Pain Committee is to improve the quality of pain management in children. The ESPA Pain Management Ladder is a clinical practice advisory based upon expert consensus to help to ensure a basic standard of perioperative pain management for all children. Further steps are suggested to improve pain management once a basic standard has been achieved. The guidance is grouped by the type of surgical procedure and layered to suggest basic, intermediate, and advanced pain management methods. The committee members are aware that there are marked differences in financial and personal resources in different institutions and countries and also considerable variations in the availability of analgesic drugs across Europe. We recommend that the guidance should be used as a framework to guide best practice
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