2,107 research outputs found
1000 Norms Project: Protocol of a cross-sectional study cataloging human variation
Background Clinical decision-making regarding diagnosis and management largely depends on comparison with healthy or ânormalâ values. Physiotherapists and researchers therefore need access to robust patient-centred outcome measures and appropriate reference values. However there is a lack of high-quality reference data for many clinical measures. The aim of the 1000 Norms Project is to generate a freely accessible database of musculoskeletal and neurological reference values representative of the healthy population across the lifespan. Methods/design In 2012 the 1000 Norms Project Consortium defined the concept of ânormalâ, established a sampling strategy and selected measures based on clinical significance, psychometric properties and the need for reference data. Musculoskeletal and neurological items tapping the constructs of dexterity, balance, ambulation, joint range of motion, strength and power, endurance and motor planning will be collected in this cross-sectional study. Standardised questionnaires will evaluate quality of life, physical activity, and musculoskeletal health. Saliva DNA will be analysed for the ACTN3 genotype (âgene for speedâ). A volunteer cohort of 1000 participants aged 3 to 100 years will be recruited according to a set of self-reported health criteria. Descriptive statistics will be generated, creating tables of mean values and standard deviations stratified for age and gender. Quantile regression equations will be used to generate age charts and age-specific centile values. Discussion This project will be a powerful resource to assist physiotherapists and clinicians across all areas of healthcare to diagnose pathology, track disease progression and evaluate treatment response. This reference dataset will also contribute to the development of robust patient-centred clinical trial outcome measures
A Cautionary Tale: MARVELS Brown Dwarf Candidate Reveals Itself To Be A Very Long Period, Highly Eccentric Spectroscopic Stellar Binary
We report the discovery of a highly eccentric, double-lined spectroscopic
binary star system (TYC 3010-1494-1), comprising two solar-type stars that we
had initially identified as a single star with a brown dwarf companion. At the
moderate resolving power of the MARVELS spectrograph and the spectrographs used
for subsequent radial-velocity (RV) measurements (R ~ <30,000), this particular
stellar binary mimics a single-lined binary with an RV signal that would be
induced by a brown dwarf companion (Msin(i)~50 M_Jup) to a solar-type primary.
At least three properties of this system allow it to masquerade as a single
star with a very low-mass companion: its large eccentricity (e~0.8), its
relatively long period (P~238 days), and the approximately perpendicular
orientation of the semi-major axis with respect to the line of sight (omega~189
degrees). As a result of these properties, for ~95% of the orbit the two sets
of stellar spectral lines are completely blended, and the RV measurements based
on centroiding on the apparently single-lined spectrum is very well fit by an
orbit solution indicative of a brown dwarf companion on a more circular orbit
(e~0.3). Only during the ~5% of the orbit near periastron passage does the
true, double-lined nature and large RV amplitude of ~15 km/s reveal itself. The
discovery of this binary system is an important lesson for RV surveys searching
for substellar companions; at a given resolution and observing cadence, a
survey will be susceptible to these kinds of astrophysical false positives for
a range of orbital parameters. Finally, for surveys like MARVELS that lack the
resolution for a useful line bisector analysis, it is imperative to monitor the
peak of the cross-correlation function for suspicious changes in width or
shape, so that such false positives can be flagged during the candidate vetting
process.Comment: 16 pages, 11 figures, 6 table
Very Low Mass Stellar and Substellar Companions to Solar-Like Stars From MARVELS V: A Low Eccentricity Brown Dwarf from the Driest Part of the Desert, MARVELS-6b
We describe the discovery of a likely brown dwarf (BD) companion with a
minimum mass of 31.7 +/- 2.0 M_Jup to GSC 03546-01452 from the MARVELS radial
velocity survey, which we designate as MARVELS-6b. For reasonable priors, our
analysis gives a probability of 72% that MARVELS-6b has a mass below the
hydrogen-burning limit of 0.072 M_Sun, and thus it is a high-confidence BD
companion. It has a moderately long orbital period of 47.8929 +0.0063/-0.0062
days with a low eccentricty of 0.1442 +0.0078/-0.0073, and a semi-amplitude of
1644 +12/-13 m/s. Moderate resolution spectroscopy of the host star has
determined the following parameters: T_eff = 5598 +/- 63, log g = 4.44 +/-
0.17, and [Fe/H] = +0.40 +/- 0.09. Based upon these measurements, GSC
03546-01452 has a probable mass and radius of M_star = 1.11 +/- 0.11 M_Sun and
R_star = 1.06 +/- 0.23 R_Sun with an age consistent with less than ~6 Gyr at a
distance of 219 +/- 21 pc from the Sun. Although MARVELS-6b is not observed to
transit, we cannot definitively rule out a transiting configuration based on
our observations. There is a visual companion detected with Lucky Imaging at
7.7 arcsec from the host star, but our analysis shows that it is not bound to
this system. The minimum mass of MARVELS-6b exists at the minimum of the mass
functions for both stars and planets, making this a rare object even compared
to other BDs.Comment: 15 pages, 15 figures, 5 tables. Accepted for publication in The
Astronomical Journa
A relocatable ocean model in support of environmental emergencies
During the Costa Concordia emergency case, regional, subregional, and relocatable ocean models have been used together with the oil spill model, MEDSLIK-II, to provide ocean currents forecasts, possible oil spill scenarios, and drifters trajectories simulations. The models results together with the evaluation of their performances are presented in this paper. In particular, we focused this work on the implementation of the Interactive Relocatable Nested Ocean Model (IRENOM), based on the Harvard Ocean Prediction System (HOPS), for the Costa Concordia emergency and on its validation using drifters released in the area of the accident. It is shown that thanks to the capability of improving easily and quickly its configuration, the IRENOM results are of greater accuracy than the results achieved using regional or subregional model products. The model topography, and to the initialization procedures, and the horizontal resolution are the key model settings to be configured. Furthermore, the IRENOM currents and the MEDSLIK-II simulated trajectories showed to be sensitive to the spatial resolution of the meteorological fields used, providing higher prediction skills with higher resolution wind forcing.MEDESS4MS Project; TESSA Project; MyOcean2 Projectinfo:eu-repo/semantics/publishedVersio
Very Low-Mass Stellar and Substellar Companions to Solar-Like Stars from MARVELS I: A Low Mass Ratio Stellar Companion to TYC 4110-01037-1 in a 79-day Orbit
TYC 4110-01037-1 has a low-mass stellar companion, whose small mass ratio and
short orbital period are atypical amongst solar-like (Teff ~< 6000 K) binary
systems. Our analysis of TYC 4110-01037-1 reveals it to be a moderately aged
(~<5 Gyr) solar-like star having a mass of 1.07 +/- 0.08 MSun and radius of
0.99 +/- 0.18 RSun. We analyze 32 radial velocity measurements from the
SDSS-III MARVELS survey as well as 6 supporting radial velocity measurements
from the SARG spectrograph on the 3.6m TNG telescope obtained over a period of
~2 years. The best Keplerian orbital fit parameters were found to have a period
of 78.994 +/- 0.012 days, an eccentricity of 0.1095 +/- 0.0023, and a
semi-amplitude of 4199 +/- 11 m/s. We determine the minimum companion mass (if
sin i = 1) to be 97.7 +/- 5.8 MJup. The system's companion to host star mass
ratio, >0.087 +/- 0.003, places it at the lowest end of observed values for
short period stellar companions to solar-like (Teff ~< 6000 K) stars. One
possible way to create such a system would be if a triple-component stellar
multiple broke up into a short period, low q binary during the cluster
dispersal phase of its lifetime. A candidate tertiary body has been identified
in the system via single-epoch, high contrast imagery. If this object is
confirmed to be co-moving, we estimate it would be a dM4 star. We present these
results in the context of our larger-scale effort to constrain the statistics
of low mass stellar and brown dwarf companions to FGK-type stars via the
MARVELS survey.Comment: 22 pages; accepted in A
Ăndice de absenteĂsmo ocupacional da equipe de enfermagem durante os impactos da pandemia de COVID-19 / Nursing staff occupational absenteeism rate during the impacts of the COVID-19 pandemic
Introdução: AbsenteĂsmo Ă© um termo usado para nomear a ausĂȘncia do trabalhador nos momentos em que este deveria estar praticando seu trabalho, e o somatĂłrio dos perĂodos em que os empregados se ausentaram, incluindo seus atrasos. As ausĂȘncias possuem uma quantidade demasiada de motivos, podendo ser referida por saĂșde relacionada Ă s condiçÔes fĂsicas, mentais e ambientais. De igual modo, a Enfermagem estĂĄ propensa a se abster pelos mesmos fatores. Objetivo: Identificar o nĂvel de absenteĂsmo nos profissionais da enfermagem em um Serviço de Pronto Atendimento (SPA) de Manaus-AM durante a pandemia de Covid-19. Metodologia: Trata-se de uma pesquisa de campo, exploratĂłria, descritiva e de natureza qualitativa, com dados coletados, os quais continham informaçÔes de prontuĂĄrios que apontavam os elementos que levaram Ă Â falta de profissionais perante o efeito da pandemia, entre o perĂodo de março de 2020 a março de 2021, e que fora realizada em um SESMT da cidade de Manaus, Amazonas, identificando os motivos que causaram o afastamento dos trabalhadores, sendo eles, enfermeiros e tĂ©cnicos de enfermagem, assim, apresentando dados obtidos para anĂĄlise do reflexo no seu dimensionamento. Resultados: Profissionais ausentes por fatores diversos, no entanto, com maior prevalĂȘncia oriundos de casos de Covid-19, acometimento do sistema respiratĂłrio e sistema Ăłsteo, condiçÔes familiares, saĂșde mental e comportamental. Maior incidĂȘncia de ausĂȘncias nos meses de maio, junho e dezembro de 2020, e janeiro de 2021. ConclusĂŁo: AtravĂ©s do estudo, fora permitido averiguar as razĂ”es pelas quais profissionais de saĂșde na ĂĄrea da Enfermagem realizaram absenteĂsmo no perĂodo pandĂȘmico, podendo assim, analisar seus fatores e reflexos no ambiente de trabalho
Search for the standard model Higgs boson in the H to ZZ to 2l 2nu channel in pp collisions at sqrt(s) = 7 TeV
A search for the standard model Higgs boson in the H to ZZ to 2l 2nu decay
channel, where l = e or mu, in pp collisions at a center-of-mass energy of 7
TeV is presented. The data were collected at the LHC, with the CMS detector,
and correspond to an integrated luminosity of 4.6 inverse femtobarns. No
significant excess is observed above the background expectation, and upper
limits are set on the Higgs boson production cross section. The presence of the
standard model Higgs boson with a mass in the 270-440 GeV range is excluded at
95% confidence level.Comment: Submitted to JHE
Combined search for the quarks of a sequential fourth generation
Results are presented from a search for a fourth generation of quarks
produced singly or in pairs in a data set corresponding to an integrated
luminosity of 5 inverse femtobarns recorded by the CMS experiment at the LHC in
2011. A novel strategy has been developed for a combined search for quarks of
the up and down type in decay channels with at least one isolated muon or
electron. Limits on the mass of the fourth-generation quarks and the relevant
Cabibbo-Kobayashi-Maskawa matrix elements are derived in the context of a
simple extension of the standard model with a sequential fourth generation of
fermions. The existence of mass-degenerate fourth-generation quarks with masses
below 685 GeV is excluded at 95% confidence level for minimal off-diagonal
mixing between the third- and the fourth-generation quarks. With a mass
difference of 25 GeV between the quark masses, the obtained limit on the masses
of the fourth-generation quarks shifts by about +/- 20 GeV. These results
significantly reduce the allowed parameter space for a fourth generation of
fermions.Comment: Replaced with published version. Added journal reference and DO
Search for New Physics with Jets and Missing Transverse Momentum in pp collisions at sqrt(s) = 7 TeV
A search for new physics is presented based on an event signature of at least
three jets accompanied by large missing transverse momentum, using a data
sample corresponding to an integrated luminosity of 36 inverse picobarns
collected in proton--proton collisions at sqrt(s)=7 TeV with the CMS detector
at the LHC. No excess of events is observed above the expected standard model
backgrounds, which are all estimated from the data. Exclusion limits are
presented for the constrained minimal supersymmetric extension of the standard
model. Cross section limits are also presented using simplified models with new
particles decaying to an undetected particle and one or two jets
Measurement of the t t-bar production cross section in the dilepton channel in pp collisions at sqrt(s) = 7 TeV
The t t-bar production cross section (sigma[t t-bar]) is measured in
proton-proton collisions at sqrt(s) = 7 TeV in data collected by the CMS
experiment, corresponding to an integrated luminosity of 2.3 inverse
femtobarns. The measurement is performed in events with two leptons (electrons
or muons) in the final state, at least two jets identified as jets originating
from b quarks, and the presence of an imbalance in transverse momentum. The
measured value of sigma[t t-bar] for a top-quark mass of 172.5 GeV is 161.9 +/-
2.5 (stat.) +5.1/-5.0 (syst.) +/- 3.6(lumi.) pb, consistent with the prediction
of the standard model.Comment: Replaced with published version. Included journal reference and DO
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