The post-lunch effect of regular and decaffeinated coffee on psychomotor performance: a randomized double-blind cross-over study

Background: This study aimed to compare the effect of regular coffee and decaffeinated coffee on psychomotor performance in healthy volunteers during post-lunch period.Methods: In this randomized double-blind cross-over study, adult healthy volunteers were given hot coffee (3 g each of regular or decaffeinated coffee) during post-lunch period. Psychomotor functions (critical flicker-fusion frequency (CFF), choice reaction time (CRT) and error count in hand-steadiness test (HST)), blood pressure and heart rate were measured pre-lunch, pre-coffee (1-hour post-lunch) and 1-hour post-coffee consumption. Subjective ratings of sleepiness and mood were also assessed during post-lunch sessions.Results: The mean age of the participants (n=16) was 27.4±2.7 years with a male: female ratio of 7:9. There was no significant deterioration in psychomotor performance post-lunch when compared to pre-lunch on both the days. The mean CFF, CRT, errors committed in HST and cardiovascular parameters did not differ significantly between regular coffee and decaffeinated groups during post-lunch sessions. There was no significant difference in values of cardiovascular parameters as well as subjective ratings of sleep and mood between two groups.Conclusions: In healthy adult individuals’ consumption of both regular coffee and decaffeinated coffee during the post-lunch period did not affect psychomotor performance

Effect of Groove Location on Pressure Profile of Twin Axial Groove Journal Bearing

The main aim of current work is to analyze the influence of groove location on the pressure profile of the hybrid journal bearing. The objective is to develop solution algorithm and computer program which will provide pressure profile developed in the space of clearance of bearing having a given value of Somerfield number. The solution algorithm shall also provide three dimensional pressure profiles of the bearing for different groove location. It was found that groove location with respect to the loading line strongly influences the parameters of performance because of the stronger groove interference in the pressurized hydrodynamic field. The comparison of circumferential pressure with angular location from +X-axis is shown for the ratio of length to diameter which comes out to be 0.5, the clearance ratio (C/R) is found to be 0.00294 while 1125 rpm is the speed. The groove axes optimal location lies between 60° to 90° (  g =0°) to the line of loading

Effect of Groove Location on Pressure Profile of Twin Axial Groove Journal Bearing

1049-1052The main aim of current work is to analyze the influence of groove location on the pressure profile of the hybrid journal bearing. The objective is to develop solution algorithm and computer program which will provide pressure profile developed in the space of clearance of bearing having a given value of Somerfield number. The solution algorithm shall also provide three dimensional pressure profiles of the bearing for different groove location. It was found that groove location with respect to the loading line strongly influences the parameters of performance because of the stronger groove interference in the pressurized hydrodynamic field. The comparison of circumferential pressure with angular location from +X-axis is shown for the ratio of length to diameter which comes out to be 0.5, the clearance ratio (C/R) is found to be 0.00294 while 1125 rpm is the speed. The groove axes optimal location lies between 60° to 90° (∝1 g =0°) to the line of loading

Accelerated microwave curing of fibre-reinforced thermoset polymer composites for structural applications: A review of scientific challenges

Accelerated curing of high performance fibre-reinforced polymer (FRP) composites via microwave heating or radiation, which can significantly reduce cure time and increase energy efficiency, has several major challenges (e.g. uneven depth of radiation penetration, reinforcing fibre shielding, uneven curing, introduction of hot spots etc). This article reviews the current scientific challenges with microwave curing of FRP composites considering the underlying physics of microwave radiation absorption in thermoset-matrix composites. The fundamental principles behind efficient accelerated curing of composites using microwave radiation heating are reviewed and presented, especially focusing on the relation between penetration depth, microwave frequency, dielectric properties and cure degree. Based on this review, major factors influencing microwave curing of thermoset-matrix composites are identified, and recommendations for efficient cure cycle design are provided

Induction of regulatory T cells: A role for probiotics and prebiotics to suppress autoimmunity.

Regulatory T cells (Tregs) are comprised of a heterogeneous population of cells that play a vital role in suppressing inflammation and maintaining immune tolerance. Given the crucial role of Tregs in maintaining immune homeostasis, it is probably not surprising that many microbial species and their metabolites have the potential to induce Tregs. There is now great interest in the therapeutic potential of probiotics and prebiotics based strategies for a range of autoimmune disorders. This review will summarise recent findings concerning the role of probiotics and prebiotics in induction of Tregs to ameliorate the autoimmune conditions. In addition, the article is focused to explain the different mechanisms of Treg induction and function by these probiotics and prebiotics, based on the available studies till date. The article further proposes that induction of Tregs by probiotics and prebiotics could lead to the development of new therapeutic approach towards curbing the autoimmune response and as an alternative to detrimental immunosuppressive drugs

Impact of COVID-19 on cardiovascular testing in the United States versus the rest of the world

Objectives: This study sought to quantify and compare the decline in volumes of cardiovascular procedures between the United States and non-US institutions during the early phase of the coronavirus disease-2019 (COVID-19) pandemic. Background: The COVID-19 pandemic has disrupted the care of many non-COVID-19 illnesses. Reductions in diagnostic cardiovascular testing around the world have led to concerns over the implications of reduced testing for cardiovascular disease (CVD) morbidity and mortality. Methods: Data were submitted to the INCAPS-COVID (International Atomic Energy Agency Non-Invasive Cardiology Protocols Study of COVID-19), a multinational registry comprising 909 institutions in 108 countries (including 155 facilities in 40 U.S. states), assessing the impact of the COVID-19 pandemic on volumes of diagnostic cardiovascular procedures. Data were obtained for April 2020 and compared with volumes of baseline procedures from March 2019. We compared laboratory characteristics, practices, and procedure volumes between U.S. and non-U.S. facilities and between U.S. geographic regions and identified factors associated with volume reduction in the United States. Results: Reductions in the volumes of procedures in the United States were similar to those in non-U.S. facilities (68% vs. 63%, respectively; p = 0.237), although U.S. facilities reported greater reductions in invasive coronary angiography (69% vs. 53%, respectively; p < 0.001). Significantly more U.S. facilities reported increased use of telehealth and patient screening measures than non-U.S. facilities, such as temperature checks, symptom screenings, and COVID-19 testing. Reductions in volumes of procedures differed between U.S. regions, with larger declines observed in the Northeast (76%) and Midwest (74%) than in the South (62%) and West (44%). Prevalence of COVID-19, staff redeployments, outpatient centers, and urban centers were associated with greater reductions in volume in U.S. facilities in a multivariable analysis. Conclusions: We observed marked reductions in U.S. cardiovascular testing in the early phase of the pandemic and significant variability between U.S. regions. The association between reductions of volumes and COVID-19 prevalence in the United States highlighted the need for proactive efforts to maintain access to cardiovascular testing in areas most affected by outbreaks of COVID-19 infection

THE MATHEMATICAL ANALYSIS OF COLUMN ORIENTED DATABASE

There are two obvious ways to map a two-dimension relational database table onto a one-dimensional storage interface: store the table row-by-row, or store the table column-by-column. Historically, database system implementations and research have focused on the row-by row data layout, since it performs best on the most common application for database systems: business transactional data processing. However, there are a set of emerging applications for database systems for which the row-by-row layout performs poorly. These applications are more analytical in nature, whose goal is to read through the data to gain new insight and use it to drive decision making and planning. In this paper, we study about the facts responsible for making Column Oriented database when traditional Row-oriented databases are already present, analysis of generation of Column Oriented databases, etc. Finally It will be conclude by giving a probabilistic analysis of Column Oriented database