607 research outputs found
Towards Quantum Repeaters with Solid-State Qubits: Spin-Photon Entanglement Generation using Self-Assembled Quantum Dots
In this chapter we review the use of spins in optically-active InAs quantum
dots as the key physical building block for constructing a quantum repeater,
with a particular focus on recent results demonstrating entanglement between a
quantum memory (electron spin qubit) and a flying qubit (polarization- or
frequency-encoded photonic qubit). This is a first step towards demonstrating
entanglement between distant quantum memories (realized with quantum dots),
which in turn is a milestone in the roadmap for building a functional quantum
repeater. We also place this experimental work in context by providing an
overview of quantum repeaters, their potential uses, and the challenges in
implementing them.Comment: 51 pages. Expanded version of a chapter to appear in "Engineering the
Atom-Photon Interaction" (Springer-Verlag, 2015; eds. A. Predojevic and M. W.
Mitchell
Experimental simulation of quantum tunneling in small systems
It is well known that quantum computers are superior to classical computers
in efficiently simulating quantum systems. Here we report the first
experimental simulation of quantum tunneling through potential barriers, a
widespread phenomenon of a unique quantum nature, via NMR techniques. Our
experiment is based on a digital particle simulation algorithm and requires
very few spin-1/2 nuclei without the need of ancillary qubits. The occurrence
of quantum tunneling through a barrier, together with the oscillation of the
state in potential wells, are clearly observed through the experimental
results. This experiment has clearly demonstrated the possibility to observe
and study profound physical phenomena within even the reach of small quantum
computers.Comment: 17 pages and 8 figure
Lithofacies uncertainty modeling in a siliciclastic reservoir setting by incorporating geological contacts and seismic information
Deterministic modeling lonely provides a unique boundary layout, depending on the geological interpretation or interpolation
from the hard available data. Changing the interpreter’s attitude or interpolation parameters leads to displacing the
location of these borders. In contrary, probabilistic modeling of geological domains such as lithofacies is a critical aspect
to providing information to take proper decision in the case of evaluation of oil reservoirs parameters, that is, applicable
for quantification of uncertainty along the boundaries. These stochastic modeling manifests itself dramatically beyond this
occasion. Conventional approaches of probabilistic modeling (object and pixel-based) mostly suffers from consideration
of contact knowledge on the simulated domains. Plurigaussian simulation algorithm, in contrast, allows reproducing the
complex transitions among the lithofacies domains and has found wide acceptance for modeling petroleum reservoirs.
Stationary assumption for this framework has implications on the homogeneous characterization of the lithofacies. In this
case, the proportion is assumed constant and the covariance function as a typical feature of spatial continuity depends only
on the Euclidean distances between two points. But, whenever there exists a heterogeneity phenomenon in the region, this
assumption does not urge model to generate the desired variability of the underlying proportion of facies over the domain.
Geophysical attributes as a secondary variable in this place, plays an important role for generation of the realistic contact
relationship between the simulated categories. In this paper, a hierarchical plurigaussian simulation approach is used to construct
multiple realizations of lithofacies by incorporating the acoustic impedance as soft data through an oil reservoir in Iran.This research was funded by the National Elites Foundation of Iran in collaboration with research Institute Petroleum of Industry in Iran under the project number of 9265005
Search for new phenomena in final states with an energetic jet and large missing transverse momentum in pp collisions at √ s = 8 TeV with the ATLAS detector
Results of a search for new phenomena in final states with an energetic jet and large missing transverse momentum are reported. The search uses 20.3 fb−1 of √ s = 8 TeV data collected in 2012 with the ATLAS detector at the LHC. Events are required to have at least one jet with pT > 120 GeV and no leptons. Nine signal regions are considered with increasing missing transverse momentum requirements between Emiss T > 150 GeV and Emiss T > 700 GeV. Good agreement is observed between the number of events in data and Standard Model expectations. The results are translated into exclusion limits on models with either large extra spatial dimensions, pair production of weakly interacting dark matter candidates, or production of very light gravitinos in a gauge-mediated supersymmetric model. In addition, limits on the production of an invisibly decaying Higgs-like boson leading to similar topologies in the final state are presente
How to evaluate the risk/benefit of trimodality therapy in locally advanced non-small-cell lung cancer
The trimodality approach represented by concurrent chemoradiotherapy followed by surgical resection is a highly effective, but potentially toxic therapy for locally advanced non-small-cell lung cancer (NSCLC). In this review, we discuss the current status of this therapy in patients with mediastinal node-positive (N2) stage III NSCLC or superior sulcus tumor, and present an overview of the principles for optimisation of the risk/benefit. Numerous clinical questions remain, and enrolment of patients into well-designed clinical trials should be encouraged
Computational and mathematical approaches to societal transitions
After an introduction of the theoretical framework and concepts of transition studies, this article gives an overview of how structural change in social systems has been studied from various disciplinary perspectives. This overview first leads to the conclusion that computational and mathematical approaches and their practical form, modeling, up till now, have been almost absent in the research and theorizing of structural change or transitions in social systems. Second, this review of the social science literature suggests numerous theoretical constructs relevant for transition modeling. Relevant concepts include the conceptualization of the micro-to-macro link, the importance of explaining both stability and change, quantitative and qualitative definitions of structural change, the use of dichotomies, synchronic and diachronic reasoning in explaining structural change, definitions of basic patterns of social change, the conceptualization of resistance to change and intentional and normative aspects of social change. This article employs these theoretical concepts to describe and discuss the models presented in this special issue in order to develop an understanding of what exactly entails a computational or mathematical approach to societal transitions
A Common Left Occipito-Temporal Dysfunction in Developmental Dyslexia and Acquired Letter-By-Letter Reading?
We used fMRI to examine functional brain abnormalities of German-speaking dyslexics who suffer from slow effortful reading but not from a reading accuracy problem. Similar to acquired cases of letter-by-letter reading, the developmental cases exhibited an abnormal strong effect of length (i.e., number of letters) on response time for words and pseudowords.Corresponding to lesions of left occipito-temporal (OT) regions in acquired cases, we found a dysfunction of this region in our developmental cases who failed to exhibit responsiveness of left OT regions to the length of words and pseudowords. This abnormality in the left OT cortex was accompanied by absent responsiveness to increased sublexical reading demands in phonological inferior frontal gyrus (IFG) regions. Interestingly, there was no abnormality in the left superior temporal cortex which--corresponding to the onological deficit explanation--is considered to be the prime locus of the reading difficulties of developmental dyslexia cases.The present functional imaging results suggest that developmental dyslexia similar to acquired letter-by-letter reading is due to a primary dysfunction of left OT regions
Seasonal and Ontogenetic Changes in Movement Patterns of Sixgill Sharks
Understanding movement patterns is fundamental to population and conservation biology. The way an animal moves through its environment influences the dynamics of local populations and will determine how susceptible it is to natural or anthropogenic perturbations. It is of particular interest to understand the patterns of movement for species which are susceptible to human activities (e.g. fishing), or that exert a large influence on community structure, such as sharks.We monitored the patterns of movement of 34 sixgill sharks Hexanchus griseus using two large-scale acoustic arrays inside and outside Puget Sound, Washington, USA. Sixgill sharks were residents in Puget Sound for up to at least four years before making large movements out of the estuary. Within Puget Sound, sixgills inhabited sites for several weeks at a time and returned to the same sites annually. Across four years, sixgills had consistent seasonal movements in which they moved to the north from winter to spring and moved to the south from summer to fall. Just prior to leaving Puget Sound, sixgills altered their behavior and moved twice as fast among sites. Nineteen of the thirty-four sixgills were detected leaving Puget Sound for the outer coast. Three of these sharks returned to Puget Sound.For most large marine predators, we have a limited understanding of how they move through their environment, and this clouds our ability to successfully manage their populations and their communities. With detailed movement information, such as that being uncovered with acoustic monitoring, we can begin to quantify the spatial and temporal impacts of large predators within the framework of their ecosystems
The Inflammatory Kinase MAP4K4 Promotes Reactivation of Kaposi's Sarcoma Herpesvirus and Enhances the Invasiveness of Infected Endothelial Cells
Kaposi's sarcoma (KS) is a mesenchymal tumour, which is caused by Kaposi's sarcoma herpesvirus (KSHV) and develops under inflammatory conditions. KSHV-infected endothelial spindle cells, the neoplastic cells in KS, show increased invasiveness, attributed to the elevated expression of metalloproteinases (MMPs) and cyclooxygenase-2 (COX-2). The majority of these spindle cells harbour latent KSHV genomes, while a minority undergoes lytic reactivation with subsequent production of new virions and viral or cellular chemo- and cytokines, which may promote tumour invasion and dissemination. In order to better understand KSHV pathogenesis, we investigated cellular mechanisms underlying the lytic reactivation of KSHV. Using a combination of small molecule library screening and siRNA silencing we found a STE20 kinase family member, MAP4K4, to be involved in KSHV reactivation from latency and to contribute to the invasive phenotype of KSHV-infected endothelial cells by regulating COX-2, MMP-7, and MMP-13 expression. This kinase is also highly expressed in KS spindle cells in vivo. These findings suggest that MAP4K4, a known mediator of inflammation, is involved in KS aetiology by regulating KSHV lytic reactivation, expression of MMPs and COX-2, and, thereby modulating invasiveness of KSHV-infected endothelial cells. © 2013 Haas et al
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